Numerical analysis of respiratory flow patterns within human upper airway

Acta Mechanica Sinica/Lixue Xuebao

Volumn 25, Issue 6, 2009, Pages 737-746

  Wang, Ying ^a   Liu, Yingxi ^a   Sun, Xiuzhen ^a,b   Yu, Shen ^a   Gao, Fei ^a  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^b DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Airflow distribution; Computational fluid dynamics; Resistance; Upper airway

Indexed keywords

AIRFLOW DISTRIBUTION; CLINICAL MEASURE; COMPUTATIONAL RESULTS; CT IMAGE; FLOW CHARACTERISTIC; FLOW-INDUCED DEFORMATION; HIGH SHEAR; NASAL CAVITY; RESPIRATORY AIRFLOW; RESPIRATORY CYCLE; RESPIRATORY FLOW; SIMULATION RESULT; TIME LEVEL; UPPER AIRWAY; WALL DEFORMATION; WALL SHEAR STRESS;

BIFURCATION (MATHEMATICS); COMPUTERIZED TOMOGRAPHY; DEFORMATION; FLOW PATTERNS; FLOW SIMULATION; FLUID DYNAMICS; FLUID STRUCTURE INTERACTION; FLUIDS; RESPIRATORY MECHANICS; SHEAR STRESS; SIMULATORS; STRENGTH OF MATERIALS; WALLS (STRUCTURAL PARTITIONS);

COMPUTATIONAL FLUID DYNAMICS;

EID: 71249147214     PISSN: 05677718     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10409-009-0283-1     Document Type: Article

References (49)

1. Kong W.J., Wang B.Q.: Otolaryngology. People's Medical Publishing House, Beijing (2002)
2. I. Hörschler M. Meinke W. Schröder 2003 Numerical simulation of the flow field in a model of the nasal cavity Comput. fluids 32 1 39 45 1009.76528 10.1016/S0045-7930(01)00097-4
3. Proctor D.F., Andersen I.: The Nose, Upper Airway Physiology and the Atmospheric Environment. Elsevier Biomedical Press, Amsterdam (1982)
4. S.K. Kim S.K. Chung 2004 An investigation on airflow in disordered nasal cavity and its corrected models by tomographic PIV Meas. Sci. Technol. 15 6 1090 1096 10.1088/0957-0233/15/6/007 2061528 (Pubitemid 38767985)
5. L. Zheng C. Kleinstreuer Z. Zhang 2007 Simulation of airflow fields and microparticle deposition in realistic human lung airway models. Part I: Airflow patterns Eur. J. Mech. B-FLUID 26 5 632 649 1117.76076 10.1016/j.euromechflu. 2007.02.003 (Pubitemid 47048728)
6. R.P. Subramaniam R.B. Richardson K.T. Morgan, et al. 1998 Computational fluid dynamics simulations of inspiratory airflow in the human nose and nasopharynx Inhal. Toxicol. 10 5 473 502 10.1080/089583798197637
7. C. Renotte V. Bouffioux F. Wilquem 2000 Numerical 3D analysis of oscillatory flow in the time-varying laryngeal channel J. Biomech. 33 12 1637 1644 10.1016/S0021-9290(00)00134-2 (Pubitemid 30690191)
8. C.L. Lin M.H. Tawhai G. McLennan, et al. 2007 Characteristics of the turbulent laryngeal jet and its effect on airflow in the human intra-thoracic airways Respir. Physiol. Neurobiol. 157 2-3 295 309 10.1016/j.resp.2007.02.006 (Pubitemid 46777492)
9. M. Girardin E. Bilgen P. Arbour 1983 Experimental study of velocity fields in a human nasal fossa by laser anemometry Ann. Otol. Rhinol. Laryngol. 92 3 pt 1 231 236
10. Y. Zhao B.B. Lieber 1994 Steady inspiratory flow in a model symmetric bifurcation J. Biomech. Eng. 116 4 488 496 10.1115/1.2895800 (Pubitemid 24376580)
11. T.E. Corcoran N. Chigier 2000 Characterization of the laryngeal jet using phase doppler interferometry J. Aerosol. Med. 13 2 125 137 10.1089/ 089426800418659
12. K.W. Stapleton E. Guentsch M.K. Hoskinson, et al. 2000 On the suitability of K-ε turbulence modeling for aerosol deposition in the mouth and throat: a comparison with experiment J. Aerosol. Sci. 31 6 739 749 10.1016/S0021- 8502(99)00547-9 (Pubitemid 30173204)
13. R.K. Calay J. Kurujareon A.E. Holdø 2002 Numerical simulation of respiratory flow patterns within human lung Respir. Physiol. Neurobiol. 130 2 201 221 10.1016/S0034-5687(01)00337-1 (Pubitemid 34848242)
14. I. Weinhold G. Mlynski 2004 Numerical simulation of airflow in the human nose Eur. Arch. Otorhinolaryngol. 261 8 452 455 10.1007/s00405-003-0675-y (Pubitemid 39304403)
15. S. Yu Y.X. Liu X.Z. Sun, et al. 2008 Influence of nasal structure on the distribution of airflow in nasal cavity Rhinology 46 2 137 143
16. D.J. Doorly D.J. Taylor R.C. Schroter 2008 Mechanics of airflow in the human nasal airways Respir. Physiol. Neurobiol. 163 1-3 100 110 10.1016/j.resp.2008.07.027
17. Z. Zhang C. Kleinstreuer 2002 Transient airflow structures and particle transport in a sequentially branching lung airway model Phys. Fluids 14 2 862 880 10.1063/1.1433495 (Pubitemid 34143782)
18. R.K. Freitas W. Schröder 2008 Numerical investigation of the three-dimensional flow in a human lung model J. Biomech. 41 11 2446 2457 10.1016/j.jbiomech.2008.05.016
19. X.Z. Sun C. Yu Y. Wang, et al. 2007 Numerical simulation of soft palate movement and airflow in human upper airway by fluid-structure interaction method Acta. Mech. Sin. 23 4 359 367 10.1007/s10409-007-0083-4 (Pubitemid 47255731)
20. C. Xu S.H. Sin J.M. McDonough, et al. 2006 Computational fluid dynamics modeling of the upper airway of children with obstructive sleep apnea syndrome in steady flow J. Biomech. 39 11 2043 2054 10.1016/j.jbiomech.2005.06.021 (Pubitemid 44038724)
21. S.J. Jeong W.S. Kim S.J. Sung 2007 Numerical investigation on the flow characteristics and aerodynamic force of the upper airway of patient with obstructive sleep apnea using computational fluid dynamics Med. Eng. Phys. 29 6 637 651 10.1016/j.medengphy.2006.08.017 (Pubitemid 46467482)
22. K. Banno M.H. Kryger 2007 Sleep apnea: Clinical investigations in humans Sleep Med. 8 4 400 426 10.1016/j.sleep.2007.03.003 (Pubitemid 46706354)
23. M.E. Ezzie J.P. Parsons J.G. Mastronarde 2008 Sleep and obstructive lung diseases Sleep Med. Clin. 3 4 505 515 10.1016/j.jsmc.2008.07.003
24. M.E. Klink R. Dodge S.F. Quan 1994 The relation of sleep complaints to respiratory symptoms in a general population Chest 105 1 151 154 10.1378/chest.105.1.151
25. L.G. Larsson B. Lundbäck A.C. Jonsson, et al. 1997 Symptoms related to snoring and sleep apnoea in subjects with chronic bronchitis: report from the obstructive lung disease in northern Sweden study Respir. Med. 91 1 5 12 10.1016/S0954-6111(97)90131-1 (Pubitemid 27105516)
26. L.G. Larsson A. Lindberg K.A. Franklin, et al. 2001 Symptoms related to obstructive sleep apnoea are common in subjects with asthma, chronic bronchitis and rhinitis in a general population Respir. Med. 95 5 423 429 10.1053/rmed.2001.1054 (Pubitemid 32624490)
27. Z. Zhang C. Kleinstreuer 2004 Airflow structures and nano-particle deposition in a human upper airway model J. Comput. Phys. 198 1 178 210 1108.76373 10.1016/j.jcp.2003.11.034 (Pubitemid 38881876)
28. Weibel E.R.: Morphometry of the Human Lung. Academic Press, New York (1963)
29. H.H. Jin J.R. Fan M.J. Zeng, et al. 2007 Large eddy simulation of inhaled particle deposition within the human upper respiratory tract J. Aerosol Sci. 38 3 257 268 10.1016/j.jaerosci.2006.09.008 (Pubitemid 46365707)
30. B. Ma K. Lutchen 2009 CFD simulation of aerosol deposition in an anatomically based human large-medium airway model Ann. Biomed. Eng. 37 2 271 285 10.1007/s10439-008-9620-y
31. C. Céline F. Redouane D. Marc, et al. 2006 In vitro experiments and numerical simulations of airflow in realistic nasal airway geometry Ann. Biomed. Eng. 34 6 997 1007 10.1007/s10439-006-9094-8 (Pubitemid 43954332)
32. C.G. Philips S.R. Kaye 1997 On the asymmetry of bifurcation in the bronchial tree Respir. Physiol. 107 1 85 98 10.1016/S0034-5687(96)02506-6 (Pubitemid 27143823)
33. H.K. Chang 1989 Flow dynamics in the respiratory tract Lung Biol. Health Dis. 40 57 138
34. Y. Liu R.M. So C.H. Zhang 2003 Modeling the bifurcating flow in an asymmetric human lung airway J. Biomech. 36 7 951 959 10.1016/S0021-9290(03) 00064-2 (Pubitemid 36566634)
35. Yang G.T., Che W.Y., Xu J.B.: Biomechanics. Chongqing Press, Chongqing (1999)
36. Huang X.Z., Wang J.B.: Practical Otorhinalaryngology. People's Medical Publishing House, Beijing (1998)
37. B. Shome L.P. Wang M.H. Santare, et al. 1998 Modeling of airflow in the pharynx with application to sleep apnea J. Biomech. Eng. 120 3 416 422 10.1115/1.2798009
38. I.M. Katz B.M. Davis T.B. Martonen 1999 A numerical study of particle motion within the human larynx and trachea J. Aerosol. Sci. 30 2 173 183 10.1016/S0021-8502(98)00043-3 (Pubitemid 28491123)
39. S.E. Churchill L.L. Shackelford J.N. Georgi, et al. 2004 Morphological variation and airflow dynamics in the human nose Am. J. Hum. Biol. 16 6 625 638 10.1002/ajhb.20074 (Pubitemid 39517310)
40. Wilcox D.C.: Turbulence Modeling for CFD. DCW Industries Inc, La Canada (1993)
41. I. Hahn P.W. Scherer M.M. Mozell 1993 Velocity profiles measured for airflow through a large-scale model of the human nasal cavity J. Appl. Physiol. 75 5 2273 2287
42. K. Keyhani P.W. Scherer M.M. Mozell 1995 Numerical simulation of airflow in the human nasal cavity J. Biomech. Eng. 117 4 429 441 10.1115/1.2794204
43. R. Chowdhary V. Singh A.E. Tattersfield, et al. 1999 Relationship of flow and cross-sectional area to frictional stress in airway models of asthma J. Asthma 36 5 419 426 10.3109/02770909909087284
44. A.S. Green 2004 Modelling of peak-flow wall shear stress in major airways of the lung J. Biomech. 37 5 661 667 10.1016/j.jbiomech.2003.09.024 (Pubitemid 38445028)
45. Y.Q. Huang A. Malhotra D.P. White 2005 Computational simulation of human upper airway collapse using a pressure-/state-dependent model of genioglossal muscle contraction under laminar flow conditions J. Appl. Physiol. 99 3 1138 1148 10.1152/japplphysiol.00668.2004 (Pubitemid 41214533)
46. F. Chouly A.V. Hirtum P.Y. Lagrée, et al. 2008 Numerical and experimental study of expiratory flow in the case of major upper airway obstructions with fluid-structure interaction J. Fluid. Struct. 24 2 250 269 10.1016/j.jfluidstructs.2007.08.004 (Pubitemid 351292466)
47. Fung Y.C.: Biomechanics-Mechanical Properties of Living Tissues. Springer, New York (1993)
48. A. Malhortra Y. Huang R.B. Fogel, et al. 2002 The male predisposition to pharyngeal collapse: importance of airway length Am. J. Respir. Crit. Care Med. 166 10 1388 1395 10.1164/rccm.2112072 (Pubitemid 35292707)
49. Chun X.: Computational mechanics models for studying the pathogenesis of obstructive sleep apnea (OSA). Ph.D. Dissertation, Drexel University, Philadelphia (2005)