Validation of computational fluid dynamics methodology used for human upper airway flow simulations

Journal of Biomechanics

Volumn 42, Issue 10, 2009, Pages 1553-1559

  Mylavarapu, Goutham ^a   Murugappan, Shanmugam ^b   Mihaescu, Mihai ^a   Kalra, Maninder ^c   Khosla, Sid ^b   Gutmark, Ephraim ^a,c  

^a University of Cincinnati   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

CFD; Obstructive sleep apnea; Pharyngeal airway; Validation

Indexed keywords

COMPUTER PROGRAMMING; COMPUTER SOFTWARE; LARGE EDDY SIMULATION; MAGNETIC RESONANCE IMAGING; NAVIER STOKES EQUATIONS; RESPIRATORY MECHANICS; SHEAR STRESS; SLEEP RESEARCH; TURBULENCE MODELS; WALL FLOW; WALLS (STRUCTURAL PARTITIONS);

COMPUTATIONAL FLUID DYNAMICS SIMULATIONS; HUMAN UPPER AIRWAY MODEL; OBSTRUCTIVE SLEEP APNEA; PHARYNGEAL AIRWAY; REYNOLDS-AVERAGED NAVIER-STOKES; STATIC PRESSURE MEASUREMENTS; TWO-EQUATION TURBULENCE MODELS; VALIDATION;

COMPUTATIONAL FLUID DYNAMICS;

ACCURACY; ADOLESCENT; ANATOMICAL VARIATION; ARTICLE; COMPUTATIONAL FLUID DYNAMICS; COMPUTER SIMULATION; CONTROLLED STUDY; EXPERIMENTAL STUDY; EXPIRATORY FLOW RATE; FLOW MEASUREMENT; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PEAK EXPIRATORY FLOW; PRESSURE MEASUREMENT; PRIORITY JOURNAL; RESPIRATORY AIRFLOW; TURBULENT FLOW; UPPER RESPIRATORY TRACT; VALIDITY;

EID: 67649464214     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2009.03.035     Document Type: Article

References (22)

1. Aittokallio T., Gyllenberg M., and Polo O. A model of a snorer's upper airway. Mathematical Biosciences 170 1 (2001) 79-90
2. Allen G.M., Shortall B.P., Gemci T., Corcoran T.E., and Chigier N.A. Computational simulations of airflow in an in-vitro model of the pediatric upper airways. Journal of Biomechanical Engineering 126 5 (2004) 604-613
3. Arens R., McDonough J.M., Corbin A.M., Rubin N.K., Carroll M.E., Pack A.I., Liu J., and Udupa J.K. Upper airway size analysis by magnetic resonance imaging of children with obstructive sleep apnea syndrome. American Journal of Respiratory and Critical Care Medicine 167 1 (2003) 65-70
4. Arens R., McDonough J.M., Costarino A.T., Mahboubi S., Tayag-Kier C.E., Maislin G., Schwab R.J., and Pack A.I. Magnetic resonance imaging of the upper airway structure of children with obstructive sleep apnea syndrome. American Journal of Respiratory and Critical Care Medicine 164 4 (2001) 698-703
5. Ayappa I., and Rapoport D.M. The upper airway in sleep: physiology of the pharynx. Sleep Medicine Reviews 7 1 (2003) 9-33
6. Croce C., Fodil R., Durand M., Sbirlea-Apiou G., Caillibotte G., Papon J.-F., Blondeau J.-R., Coste A., Isabey D., and Louis B. In-vitro experiments and numerical simulations of airflow in realistic Nasal airway geometry. Annals of Biomedical Engineering 34 6 (2006) 997-1007
7. De Backer J.W., Vanderveken O.M., Vos W.G., Devolder A., Verhulst S.L., Verbraecken J.A., Parizel P.M., Braem M.J., Van de Heyning P.H., and De Backer W.A. Functional imaging using computational fluid dynamics to predict treatment success of mandibular advancement devices in sleep-disordered breathing. Journal of Biomechanics 40 16 (2007) 3708-3714
8. Gemci T., Ponyavin V., Chen Y., Chen H., and Collins R. Computational model of airflow in upper 17 generations of human respiratory tract. Journal of Biomechanics 41 9 (2008) 2047-2054
9. Guilleminault C., Tilkian A., and Dement W.C. The sleep apnea syndromes. Annual Review of Medicine 27 1 (1976) 465-484
10. Jeong S.-J., Kim W.-S., and Sung S.-J. Numerical investigation on the flow characteristics and aerodynamic force of the upper airway of patient with obstructive sleep apnea using computational fluid dynamics. Medical Engineering & Physics 29 6 (2007) 637-651
11. Keyhani K., Scherer P.W., and Mozell M.M. Numerical simulation of airflow in the human nasal cavity. Journal of Biomechanical Engineering 117 4 (1995) 429-441
12. Malhotra A., Huang Y., Fogel R.B., Pillar G., Edwards J.K., Kikinis R., Loring S.H., and White D.P. The male predisposition to pharyngeal collapse: importance of airway length. American Journal of Respiratory and Critical Care Medicine 166 10 (2002) 1388-1395
13. Mihaescu M., Murugappan S., Gutmark E., Donnelly L.F., Khosla S., and Kalra M. Computational fluid dynamics analysis of upper airway reconstructed from magnetic resonance imaging data. Annals of Otology, Rhinology and Laryngology 117 4 (2008) 303-309
14. Mihaescu M., Murugappan S., Kalra M., Khosla S., and Gutmark E. Large eddy simulation and Reynolds-averaged Navier-stokes modeling of flow in a realistic pharyngeal airway model: an investigation of obstructive sleep apnea. Journal of Biomechanics 41 10 (2008) 2279-2288
15. Pope S.B. Turbulent Flows (2000), Cambridge University Press, Cambridge
16. Ryan C.M., and Bradley T.D. Pathogenesis of obstructive sleep apnea. Journal of Applied Physiology 99 6 (2005) 2440-2450
17. Sung S.J., Jeong S.J., Yu Y.S., Hwang C.J., and Pae E.K. Customized three-dimensional computational fluid dynamics simulation of the upper airway of obstructive sleep apnea. Angle Orthodontics. 76 5 (2006) 791-799
18. Van Doormaal J.P., and Raithby G.D. Enhancements of the SIMPLE method for predicting incompressible fluid flows. Numerical Heat Transfer, Part A: Applications 7 2 (1984) 147-163
19. van Ertbruggen C., Corieri P., Theunissen R., Riethmuller M.L., and Darquenne C. Validation of CFD predictions of flow in a 3D-alveolated bend with experimental data. Journal of Biomechanics 41 2 (2008) 399-405
20. Wilcox D.C. Turbulence Modeling for CFD (1993), DCW Industries, Inc., La Cãnada, CA
21. Xu C., Sin S., McDonough J.M., Udupa J.K., Guez A., Arens R., and Wootton D.M. Computational fluid dynamics modeling of the upper airway of children with obstructive sleep apnea syndrome in steady flow. Journal of Biomechanics 39 11 (2006) 2043-2054
22. Young T., Palta M., Dempsey J., Skatrud J., Weber S., and Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. The New England Journal of Medicine 328 17 (1993) 1230-1235