Mechanics of airflow in the human nasal airways

Respiratory Physiology and Neurobiology

Volumn 163, Issue 1-3, 2008, Pages 100-110

  Doorly, D J ^a   Taylor, D J ^a   Schroter, R C ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Computational biomechanics; Nasal airways; Particle image velocimetry; Physiological flows

Indexed keywords

AIRWAY DYNAMICS; ARTICLE; BIOMECHANICS; COMPUTER MODEL; COMPUTER SIMULATION; NOSE AIRFLOW; NOSE CAVITY; PHYSICAL MODEL; PRIORITY JOURNAL; SHEAR STRESS;

COMPUTER SIMULATION; HUMANS; MECHANICS; MODELS, BIOLOGICAL; NASAL CAVITY; PULMONARY VENTILATION;

EID: 54049108391     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2008.07.027     Document Type: Article

References (79)

1. Bailie N., Hanna B., Watterson J., and Gallagher G. An overview of numerical modelling of nasal airflow. Rhinology 44 1 (2006) 53-57
2. Blum H. A transformation for extracting new descriptors of shape. Models for the Perception of Speech and Visual Form (1967), M.I.T. Press pp. 362-380
3. Brucker C., and Park K. Experimental study of velocity fields in a model of human nasal cavity by DPIV. In: Banerjee S., and Eaton K. (Eds). Proceedings 1st International Symposium on Turbulence and Shear Phenomena. September, 12-15, Begell House, Santa Barbara, California (1999) 831-836
4. Cakmak O., Coskun M., Celik H., Buyuklu F., and Ozluoglu L.N. Value of acoustic rhinometry for measuring nasal valve area. Laryngoscope 113 (2003) 295-302
5. Carey J.W., and Steegmann A.T.J. Human nasal protrusion, latitude, and climate. Am. J. Phys. Anthropol. 56 (1981) 313-319
6. Chung S.K., and Kim S.K. Digital particle image velocimetry studies of nasal airflow. Respir. Physiol. Neurobiol. (2008)
7. Churchill S.E., Shackelford L.L., Georgi J.N., and Black M.T. Morphological variation and airflow dynamics in the human nose. Am. J. Hum. Biol. 16 (2004) 625-638
8. Cole P. Biophysics of nasal airflow: a review. Am. J. Rhinol. (2000) 245-249
9. Cotter, C.J., 2008. The variational particle-mesh method for matching curves. J. Phys. A. 41 344003 (18 pp.) doi:10.1088/1751-8113/41/34/344003.
10. Croce C., Fodil R., Durand M., Sbirlea-Apiou G., Caillibotte G., Papon J.F., Blondeau J.R., Coste A., Isabey D., and Louis B. In vitro experiments and numerical simulations of airflow in realistic nasal airway geometry. Ann. Biomed. Eng. 34 (2006) 997-1007
11. Doorly D.J., Taylor D.J., Franke P., and Schroter R.C. Experimental investigation of nasal airflow. Proc. Inst. Mech. Eng. H: J. Eng. Med. 222 (2008) 439-453 10.1243/09544119jeim330
12. Doorly D.J., Taylor D.J., Gambaruto A.M., Schroter R.C., and Tolley N. Nasal architecture: form and flow. Philos. Trans. R. Soc. A 366 (2008) 3225-3246 10.1098/rsta.2008.0083
13. Eccles R. Nasal airflow in health and disease. Acta Otolaryngol. 120 5 (2000) 580-595
14. Elad D., Naftali S., Rosenfeld M., and Wolf M. Physical stresses at the air-wall interface of the human nasal cavity during breathing. J. Appl. Physiol. 100 (2006) 1003-1010
15. Elad D., Wolf M., and Keck T. Air-conditioning in the human nasal cavity. Respir. Physiol. Neurobiol. (2008)
16. Finck M., Hanel D., and Wlokas I. Simulation of nasal flow by lattice Boltzmann methods. Comput. Biol. Med. 37 (2007) 739-749
17. Fodil R., Brugel-Ribere L., Croce C., Sbirlea-Apiou G., Larger C., Papon J.F., Delclaux C., Coste A., Isabey D., and Louis B. Inspiratory flow in the nose: a model coupling flow and vasoerectile tissue distensibility. J. Appl. Physiol. 98 (2005) 288-295
18. Franke V.E., Franke P.T., Doorly D.J., Schroter R.C., Giordana S., and Almeyda R. Computational modelling of flow in the nasal cavities. Proceedings of the ASME SBC05 Summer Bioengineering Meeting. June 22-26, 2005, Colorado, USA (2005)
19. Gambaruto, A.M., 2007. Form and flow in anatomical conduits: bypass graft and nasal cavity. Ph.D. Thesis, Department of Aeronautics, Imperial College London.
20. Gambaruto A.M., Taylor D.J., and Doorly D.J. Modelling nasal airflow using a Fourier descriptor representation of geometry. Int. J. Numer. Methods Fluids (2008) 10.1002/fld.1866
21. Garcia G.J.M., Bailie N., Martins D.A., and Kimbell J.S. Atrophic rhinitis: a CFD study of air conditioning in the nasal cavity. J. Appl. Physiol. 103 (2007) 1082-1092
22. Girardin M., Bilgen E., and Arbour P. Experimental study of velocity fields in a human nasal fossa by laser anemometry. Ann. Otol. Rhinol. Laryngol. 92 (1983) 231-236
23. Guilmette R.A., Birchall A., and Jarvis N.S. Effect of uncertainty in nasal airway deposition of radioactive particles on effective dose. Radiat. Prot. Dosim. 79 1-4 (1998) 245-248
24. Hahn I., Scherer P.W., and Mozell M.M. Velocity profiles measured for airflow through a large-scale model of the human nasal cavity. Model. Physiol. 75 (1993) 2273-2287
25. Hanif J., Jawad S.S.M., and Eccles R. The nasal cycle in health and disease. Clin. Otolaryngol. 25 6 (2000) 461-467
26. Hopkins L.M., Kelly J.T., Wexler A.S., and Prasad A.K. Particle image velocimetry measurements in complex geometries. Exp. Fluids 29 1 (2000) 91-95
27. Hornung D.E., Leopold D.A., Youngentob S.L., Sheehe P.R., Gagne G.M., Thomas F.D., and Mozell M.M. Airflow patterns in a human nasal model. Arch. Otolaryngol. Head Neck Surg. 113 (1987) 169-172
28. Horschler I., Brucker C., Schroder W., and Meinke M. Investigation of the impact of the geometry on the nose flow. Eur. J. Mech. Fluids 25 (2006) 471-490
29. Horschler I., Meinke M., and Schroder W. Numerical simulation of the flow field in a model of the nasal cavity. Comput. Fluids 32 (2003) 39-45
30. Inthavong K., Tian Z., Li H., Tu J., Yang W., Xue C., and Li C. A numerical study of spray particle deposition in a human nasal cavity. Aerosol Sci. Technol. 40 11 (2006) 1034-1045
31. Inthavong K., Tiana Z.F., Tua J.Y., Yangb W., and Xuec C. Optimising nasal spray parameters for efficient drug delivery using computational fluid dynamics. Comput. Biol. Med. 38 6 (2008) 713-726
32. Ishikawa S., Nakayama T., Watanabe M., and Matsuzawa T. Visualization of flow resistance in physiological nasal respiration. Arch. Otolaryngol. Head Neck Surg. 132 (2006) 1203-1209
33. Jain A.K. Fundamentals of Digital Image Processing (1988), Prentice-Hall International Editions pp. 370-374, 382-383
34. Kelly J.T., Asgharian B., Kimbell J., and Wong B.A. Particle deposition in human nasal airway replicas manufactured by different methods. Part I. Inertial regime particles. Aerosol Sci. Technol. 38 (2004) 1072-1079
35. Kelly J.T., Asgharian B., Kimbell J., and Wong B.A. Particle deposition in human nasal airway replicas manufactured by different methods. Part II. Ultrafine particles. Aerosol Sci. Technol. 38 (2004) 1072-1079
36. Keyhani K., Scherer P.W., and Mozell M.M. Numerical simulation of airflow in the human nasal cavity. J. Biomech. Eng. 117 (1995) 429-441
37. Keyhani K., Scherer P.W., and Mozell M.M. A numerical model of nasal odorant transport for the analysis of human olfaction. J. Theor. Biol. 186 3 (1997) 279-301
38. Kim J.K., Yoon J.H., Kim C.H., Nam T.W., Shim D.B., and Shin H.A. Particle image velocimetry measurements for the study of nasal airflow. Acta Otolaryngol. 126 3 (2006) 282-287
39. Kim S.K., and Chung S.K. An investigation on airflow in disordered nasal cavity and its corrected models by tomographic PIV. Meas. Sci. Technol. 15 (2004) 1090-1096
40. Kimbell J.S., Segal R., Asgharian B., Wong B.A., Schroeter J.D., Southall J.P., Dickens C.J., Brace G., and Miller F.J. Characterization of deposition from nasal spray devices using a computational fluid dynamics model of the human nasal passages. J. Aerosol Med. 20 (2007) 59-74
41. Kleven M., MeLaaen M.C., Reimers M., Rotnes J.S., Aurdal L., and Djupesland P.G. Using Computational Fluid Dynamics (CFD) to improve the bi-directional nasal drug delivery concept. Food Bioprod. Process. 83 C2 (2005) 107-117
42. Kobbelt L., Campagna S., Vorsatz J., and Seidel P.H. Interactive multi-resolution modeling on arbitrary meshes. Proceedings of the International Conference on Computer Graphics and Interactive Techniques (1998) 105-114
43. Lang J. Clinical Anatomy of the Nose, Nasal Cavity and Paranasal Sinuses (1989), George Thieme Verlag, New York
44. Lindemann J., Keck T., Wiesmiller K.M., Rettinger G., Brambs H.J., and Pless D. Numerical simulation of intranasal air flow and temperature after resection of the turbinates. Rhinology 43 (2005) 24-28
45. Lindemann J., Brambs H.J., Keck T., Wiesmiller K.M., Rettinger G., and Pless D. Numerical simulation of intranasal airflow after radical sinus surgery. Am. J. Otolaryngol. 26 3 (2005) 175-180
46. Lindemann J., Keck T., Wiesmiller K., Sander B., Brambs H.J., Rettinger G., and Pless D. A numerical simulation of intranasal air temperature during inspiration. Laryngoscope 114 (2004) 1037-1041
47. Márquez Dorsch F., Cenjor Español C., and Gutiérrez Fonseca R. Acoustic rhinometry in a normal population. Acta Otorrinolaringol. Esp. 47 2 (1996) 121-124
48. Mygind N., and Dahl R. Anatomy, physiology and function of the nasal cavities in health and disease. Adv. Drug Deliv. Rev. 29 1/2 (1998) 3-12
49. Naftali S., Rosenfeld M., Wolf M., and Elad D. The air-conditioning capacity of the human nose. Ann. Biomed. Eng. 33 (2005) 545-553
50. Naftali S., Schroter R.C., Shiner R.J., and Elad D. Transport phenomena in the human nasal cavity: a computational model. Ann. Biomed. Eng. 26 (1998) 831-839
51. Negus V. Comparative Anatomy and Physiology of the Nose and Paranasal Sinuses (1958), F. and S. Livingstone Ltd., Edinburgh/London
52. Numminem J. Clinical Validation of Rhinometric Measurements, Academic Dissertation (2003), University of Tampere, Tampere, Finland
53. Ohki M., Naito K., and Cole P. Dimension and resistance of the human nose: racial differences. Laryngoscope 101 (1991) 276-278
54. Proctor D.F. The upper airways: nasal physiology and defense of the lungs. Am. Rev. Respir. Dis. 115 (1977) 97-129
55. Proctor D.F. Form and function in the upper airways and larynx (Chapter 6). In: Fishman A.P. (Ed). The Handbook of Physiology Section 3: The Respiratory System Volume III. Mechanics of Breathing, Part 1 (1986), The American Physiological Society, Maryland 63-73
56. Proetz A.W. Air currents in the upper respiratory tract and their clinical importance. Ann. Otol. Rhinol. Laryngol. 60 (1951) 439-467
57. Schreck S., Sullivan K.J., Ho C.M., and Chang H.K. Correlations between flow resistance and geometry in a model of the human nose. J. Appl. Physiol. 75 (1993) 1767-1775
58. Schroeter J.D., Kimbell J.S., and Asgharian B. Analysis of particle deposition in the turbinate and olfactory regions using a human nasal computational fluid dynamics model. J. Aerosol Med.-Deposition Clearance and Effects in the Lung 19 3 (2006) 301-313
59. Schwab K.H., and v Hagens G. Freeze substitution of macroscopic specimens for plastination. Abstract: Sixth European Anatomical Congress. Acta Anat. 111 12 (1981) 399
60. Shaida A.M., and Kenyon G.S. The nasal valves: changes in anatomy and physiology in normal subjects. Rhinology 38 (2000) 7-12
61. Shi H., Kleinstreuer C., and Zhang Z. Laminar airflow and nanoparticle or vapor deposition in a human nasal cavity model. ASME J. Biomech. Eng. 128 (2006) 697-706
62. Shi H., Kleinstreuer C., and Zhang Z. Modeling of inertial particle transport and deposition in human nasal cavities with wall roughness. J. Aerosol Sci. 38 (2007) 398-419
63. Simmen D., Scherrer J.L., Moe K., and Heinz H. A dynamic and direct visualization model for the study of nasal airflow. Arch. Otolaryngol. Head Neck Surg. 125 (1999) 1015-1021
64. Sonka M. Image Processing, Analysis and Machine Vision (1995), Chapman and Hall Computing pp. 422-442, 192-242
65. Subramaniam R.P., Richardson R.B., Morgan K.T., and Kimbell J.S. Computational fluid dynamics simulations of inspiratory airflow in the human nose and nasopharynx. Inhal. Toxicol. 10 2 (1998) 91-120
66. Suzina A.H., Hamzah M., and Samsudin A.R. Active anterior rhinomanometry analysis in normal adult Malays. J. Laryngol. Otol. 117 (2003) 605-608
67. Swift D.L., and Proctor D.F. Access of air to the respiratory tract. Respir. Defense Mech. (1977) 63-91
68. Taylor D.J., Franke V.E., Doorly D.J., and Schroter R.C. Airflow in the human nasal cavity. Proceedings of the ASME SBC05 Summer Bioengineering Meeting. June 22-26, 2005, Colorado, USA (2005)
69. Taylor, D.J., Doorly, D.J., Schroter, R.C., 2008a. Inflow boundary profile effects on numerical simulations of nasal airflow, Imperial College Aeronautics Report IC 08-01. Extended account also to be published.
70. Taylor, D.J., Gambaruto, A.M., Tebutt, G., Doorly, D.J., Schroter, R.C., 2008. Computational simulation of nasal airflow: convergence and sensitivity. To be published.
71. von Hagens G., Tiedemann K., and Kriz W. The current potential of plastination. Anat. Embryol. 175 (1987) 41-421
72. Weeks Jr. A.R. Fundamentals of Electronic Image Processing (1996), SPIE/IEEE Series on Image Science and Engineering pp. 333-359, 452-470
73. Weinhold I., and Mlynski G. Numerical simulation of airflow in the human nose. Eur. Arch. Otorhinolaryngol. 261 (2004) 452-455
74. Wen J., Inthavong K., Tu J., and Wang S. Numerical simulations for detailed airflow dynamics in a human nasal cavity. Respir. Physiol. Neurobiol. 161 2 (2008) 125-135
75. Wexler D., Segal R., and Kimbell J. Aerodynamic effects of inferior turbinate reduction computational fluid dynamics simulation. Arch. Otolaryngol. Head Neck Surg. 131 (2005) 1102-1107
76. Wolf M., Naftali S., Schroter R.C., and Elad D. Air-conditioning characteristics of the human nose. J. Laryngol. Otol. 118 (2004) 87-92
77. Zhang Z., and Kleinstreuer C. Airflow structures and nano-particle deposition in a human upper airway model. J. Comput. Phys. 198 (2004) 178-210
78. Zhao Z., Scherer P.W., Hajiloo S.A., and Dalton P. Effect of anatomy on human nasal air flow and odorant transport patterns: implications for olfaction. Chem. Senses 29 (2004) 365-379
79. Zhao K., Dalton P., Yang G.C., and Scherer P.W. Numerical modeling of turbulent and laminar airflow and odorant transport during sniffing in the human and rat nose. Chem. Senses 31 2 (2006) 107-118