메뉴 건너뛰기




Volumn 42, Issue 1, 2012, Pages 39-49

Numerical analysis of micro- and nano-particle deposition in a realistic human upper airway

Author keywords

CFD; Human Upper Airway; Micro particle; Nano particle

Indexed keywords

3D MODELS; COMPUTATIONAL MODEL; CT-SCAN IMAGES; DEPOSITION FRACTIONS; EULERIAN APPROACH; HOT SPOT; HUMAN UPPER AIRWAY; INHALED PARTICLES; LAGRANGIAN; MICRO-PARTICLE; MICRO-PARTICLES; NASAL CAVITY; OROPHARYNX; PARTICLE DEPOSITIONS; UPPER AIRWAY;

EID: 83855162774     PISSN: 00104825     EISSN: 18790534     Source Type: Journal    
DOI: 10.1016/j.compbiomed.2011.10.005     Document Type: Article
Times cited : (103)

References (41)
  • 1
    • 18544398517 scopus 로고    scopus 로고
    • Local particle deposition patterns may play a key role in the development of lung cancer
    • Balásházy I., Hofmann W., Heistracher T. Local particle deposition patterns may play a key role in the development of lung cancer. J. Appl. Physiol. 2003, 94:1719-1725.
    • (2003) J. Appl. Physiol. , vol.94 , pp. 1719-1725
    • Balásházy, I.1    Hofmann, W.2    Heistracher, T.3
  • 3
    • 0034837420 scopus 로고    scopus 로고
    • Systemic and cardiovascular effects of airway injury and inflammation: ultrafine particle exposure in humans
    • Frampton M.W. Systemic and cardiovascular effects of airway injury and inflammation: ultrafine particle exposure in humans. Environ. Health Persp. 2001, 109:529-532.
    • (2001) Environ. Health Persp. , vol.109 , pp. 529-532
    • Frampton, M.W.1
  • 5
    • 0035140471 scopus 로고    scopus 로고
    • Pulmonary effects of inhaled ultrafine particles
    • Oberdörster G. Pulmonary effects of inhaled ultrafine particles. Int. Arch. Occup. Env. Health 2001, 74:1-8.
    • (2001) Int. Arch. Occup. Env. Health , vol.74 , pp. 1-8
    • Oberdörster, G.1
  • 6
    • 0032101028 scopus 로고    scopus 로고
    • Engines and nanoparticles: a review
    • Kittelson D.B. Engines and nanoparticles: a review. J. Aerosol Sci. 1998, 29(5-6):575-588.
    • (1998) J. Aerosol Sci. , vol.29 , Issue.5-6 , pp. 575-588
    • Kittelson, D.B.1
  • 7
    • 4344594118 scopus 로고    scopus 로고
    • A review of the influence of particle size, puff volume and inhalation pattern on the deposition of cigarette smoke particles in the respiratory tract
    • Bernstein G.M. A review of the influence of particle size, puff volume and inhalation pattern on the deposition of cigarette smoke particles in the respiratory tract. Inhalation Toxicol. 2004, 16:675-689.
    • (2004) Inhalation Toxicol. , vol.16 , pp. 675-689
    • Bernstein, G.M.1
  • 8
    • 0001312553 scopus 로고
    • Particle size studies on tobacco smoke
    • Keith C.H. Particle size studies on tobacco smoke. Beitr. Tabakforsch. 1982, 11(3):123-131.
    • (1982) Beitr. Tabakforsch. , vol.11 , Issue.3 , pp. 123-131
    • Keith, C.H.1
  • 11
    • 33846059406 scopus 로고    scopus 로고
    • Validity of in vitro tests on aqueous spray pumps as surrogates for nasal deposition, absorption, and biologic response
    • Suman J.D., Laube B.L., Dalby R. Validity of in vitro tests on aqueous spray pumps as surrogates for nasal deposition, absorption, and biologic response. J. Aerosol Med. 2006, 19(4):510-521.
    • (2006) J. Aerosol Med. , vol.19 , Issue.4 , pp. 510-521
    • Suman, J.D.1    Laube, B.L.2    Dalby, R.3
  • 12
    • 33845571480 scopus 로고    scopus 로고
    • Computational investigation of particle inertia effects on submicron aerosol deposition in the respiratory tract
    • Longest P.W., Xi J. Computational investigation of particle inertia effects on submicron aerosol deposition in the respiratory tract. J. Aerosol Sci. 2007, 38(1):111-130.
    • (2007) J. Aerosol Sci. , vol.38 , Issue.1 , pp. 111-130
    • Longest, P.W.1    Xi, J.2
  • 13
    • 33749006561 scopus 로고    scopus 로고
    • CFD simulation of nasal airflow: towards treatment planning for functional rhinosurgery
    • Zachow S., Steinmann A., Hildebrandt T., Weber R., Heppt W. CFD simulation of nasal airflow: towards treatment planning for functional rhinosurgery. Int. Congr. Ser. 2006, 165-167.
    • (2006) Int. Congr. Ser. , pp. 165-167
    • Zachow, S.1    Steinmann, A.2    Hildebrandt, T.3    Weber, R.4    Heppt, W.5
  • 14
    • 42249097561 scopus 로고    scopus 로고
    • Numerical simulations for detailed airflow dynamics in a human nasal cavity
    • Wen J., Inthavong K., Tu J.Y., Wang S. Numerical simulations for detailed airflow dynamics in a human nasal cavity. Respir. Physiol. Neurobiol. 2008, 125-135.
    • (2008) Respir. Physiol. Neurobiol. , pp. 125-135
    • Wen, J.1    Inthavong, K.2    Tu, J.Y.3    Wang, S.4
  • 16
    • 53049088434 scopus 로고    scopus 로고
    • Numerical predictions of submicronmeter aerosol deposition in the nasal cavity using a novel drift flux approach
    • Xi J., Longest P.W. Numerical predictions of submicronmeter aerosol deposition in the nasal cavity using a novel drift flux approach. Int. J. Heat Mass Transfer 2008, 51:5562-5577.
    • (2008) Int. J. Heat Mass Transfer , vol.51 , pp. 5562-5577
    • Xi, J.1    Longest, P.W.2
  • 17
    • 67349115950 scopus 로고    scopus 로고
    • Comparison of micron and nano particle deposition patterns in a realistic human nasal cavity
    • Wang S., Inthavong K., Wen J., Tu J.Y., Xue C.L. Comparison of micron and nano particle deposition patterns in a realistic human nasal cavity. Respir. Physiol. Neurobiol. 2009, 166:142-151.
    • (2009) Respir. Physiol. Neurobiol. , vol.166 , pp. 142-151
    • Wang, S.1    Inthavong, K.2    Wen, J.3    Tu, J.Y.4    Xue, C.L.5
  • 18
    • 77149169388 scopus 로고    scopus 로고
    • Inhalability of micron particles through the nose and mouth
    • Se C.M., Inthavong K., Tu J.Y. Inhalability of micron particles through the nose and mouth. Inhalation Toxicol. 2010, 22(4):287-300.
    • (2010) Inhalation Toxicol. , vol.22 , Issue.4 , pp. 287-300
    • Se, C.M.1    Inthavong, K.2    Tu, J.Y.3
  • 19
    • 79954824167 scopus 로고    scopus 로고
    • Numerical investigation of septal deviation effect on deposition of nano/micro particles in human nasal passage
    • Moghadas H., Abouali O., Faramarzi A., Ahmadi G. Numerical investigation of septal deviation effect on deposition of nano/micro particles in human nasal passage. Respir. Physiol. Neurobiol. 2011, 177:9-18.
    • (2011) Respir. Physiol. Neurobiol. , vol.177 , pp. 9-18
    • Moghadas, H.1    Abouali, O.2    Faramarzi, A.3    Ahmadi, G.4
  • 20
    • 0027487191 scopus 로고
    • Velocity profiles measured for airflow through a large-scale model of the human nasal cavity
    • Hahn I., Scherer P.W., Mozell M.M. Velocity profiles measured for airflow through a large-scale model of the human nasal cavity. J. Appl. Physiol. 1993, 75:2273-2287.
    • (1993) J. Appl. Physiol. , vol.75 , pp. 2273-2287
    • Hahn, I.1    Scherer, P.W.2    Mozell, M.M.3
  • 23
    • 11344277827 scopus 로고    scopus 로고
    • Particle deposition in human nasal airway replicas manufactured by different methods, part I: inertial regime particle
    • Kelly J.T., Asgharian B., Kimbell J.S., Wong B.A. Particle deposition in human nasal airway replicas manufactured by different methods, part I: inertial regime particle. Aerosol Sci. Technol. 2004, 38:1063-1071.
    • (2004) Aerosol Sci. Technol. , vol.38 , pp. 1063-1071
    • Kelly, J.T.1    Asgharian, B.2    Kimbell, J.S.3    Wong, B.A.4
  • 24
    • 11344288915 scopus 로고    scopus 로고
    • Particle deposition in human nasal airway replicas manufactured by different methods, part II: ultrafine particles
    • Kelly J.T., Asgharian B., Kimbell J.S., Wong B.A. Particle deposition in human nasal airway replicas manufactured by different methods, part II: ultrafine particles. Aerosol Sci. Technol. 2004, 38:1072-1079.
    • (2004) Aerosol Sci. Technol. , vol.38 , pp. 1072-1079
    • Kelly, J.T.1    Asgharian, B.2    Kimbell, J.S.3    Wong, B.A.4
  • 25
    • 0036852833 scopus 로고    scopus 로고
    • Micro-particle transport and deposition in a human oral airway model
    • Zhang Z., Kleinstreuer C., Kim C.S. Micro-particle transport and deposition in a human oral airway model. J. Aerosol Sci. 2002, 33:1635-1652.
    • (2002) J. Aerosol Sci. , vol.33 , pp. 1635-1652
    • Zhang, Z.1    Kleinstreuer, C.2    Kim, C.S.3
  • 26
    • 0037323228 scopus 로고    scopus 로고
    • Laminar-to-turbulent fluid-particle flows in a human airway model
    • Kleinstreuer C., Zhang Z. Laminar-to-turbulent fluid-particle flows in a human airway model. Int. J. Multiphase Flow 2003, 29:271-289.
    • (2003) Int. J. Multiphase Flow , vol.29 , pp. 271-289
    • Kleinstreuer, C.1    Zhang, Z.2
  • 27
    • 34249053835 scopus 로고    scopus 로고
    • Fluid flow and particle deposition analysis in a realistic extrathoracic airway model using unstructured grids
    • Jayaraju S.T., Brouns M., Verbanck S., Lacor C. Fluid flow and particle deposition analysis in a realistic extrathoracic airway model using unstructured grids. J. Aerosols Sci. 2007, 38:494-508.
    • (2007) J. Aerosols Sci. , vol.38 , pp. 494-508
    • Jayaraju, S.T.1    Brouns, M.2    Verbanck, S.3    Lacor, C.4
  • 28
    • 83855165481 scopus 로고    scopus 로고
    • Micro/nano particles transport and deposition in realistic geometry of human upper airways, FEDSM2009, Vail, Colorado, USA, August
    • B. Tavakkoli, O. Abouali, M. Yazdi, M.H. Bagheri, G. Ahamdi, Micro/nano particles transport and deposition in realistic geometry of human upper airways, FEDSM2009, Vail, Colorado, USA, August, 2009.
    • (2009)
    • Tavakkoli, B.1    Abouali, O.2    Yazdi, M.3    Bagheri, M.H.4    Ahamdi, G.5
  • 29
    • 71249147214 scopus 로고    scopus 로고
    • Numerical analysis of respiratory flow patterns within human upper airway
    • Wang Y., Liu Y., Sun X., Yu Sh., Gao F. Numerical analysis of respiratory flow patterns within human upper airway. Acta Mech. Sin. 2009, 25:737-746.
    • (2009) Acta Mech. Sin. , vol.25 , pp. 737-746
    • Wang, Y.1    Liu, Y.2    Sun, X.3    Yu, S.4    Gao, F.5
  • 30
    • 67649464214 scopus 로고    scopus 로고
    • Validation of computational fluid dynamics methodology used for human upper airway flow simulations
    • Mylavarapu G., Murugappan Sh., Mihaescu M., Kalra M., Khosla S., Gutmark E. Validation of computational fluid dynamics methodology used for human upper airway flow simulations. J. Biomech. 2009, 42:1553-1559.
    • (2009) J. Biomech. , vol.42 , pp. 1553-1559
    • Mylavarapu, G.1    Murugappan, S.2    Mihaescu, M.3    Kalra, M.4    Khosla, S.5    Gutmark, E.6
  • 31
    • 78651540144 scopus 로고    scopus 로고
    • Simulation of airflow and aerosol deposition in the nasal cavity of a 5-year-old child
    • Xi J., Si X., WonKim J., Berlinski A. Simulation of airflow and aerosol deposition in the nasal cavity of a 5-year-old child. J. Aerosol Sci. 2011, 42:156-173.
    • (2011) J. Aerosol Sci. , vol.42 , pp. 156-173
    • Xi, J.1    Si, X.2    WonKim, J.3    Berlinski, A.4
  • 32
    • 37549046051 scopus 로고    scopus 로고
    • Focusing on children's inhalation dosimetry and health effects for risk assessment: an introduction, Part A: current issues
    • Foos B., Marty M., Schwartz J., Bennett W., Moya J., Jarabek A.M. Focusing on children's inhalation dosimetry and health effects for risk assessment: an introduction, Part A: current issues. J. Toxicol. Environ. Health 2008, 71(3):149-165.
    • (2008) J. Toxicol. Environ. Health , vol.71 , Issue.3 , pp. 149-165
    • Foos, B.1    Marty, M.2    Schwartz, J.3    Bennett, W.4    Moya, J.5    Jarabek, A.M.6
  • 33
    • 83855163805 scopus 로고    scopus 로고
    • G. U.S. General surgeon report. The health consequences of involuntary exposure to tobacco smoke: A report of the surgeon general-executive summary. U.S. department of health and human services, centers for disease control and prevention, coordination center for health promotion national center for chronic disease prevention and health promotion, office on smoking and health
    • G. U.S. General surgeon report. The health consequences of involuntary exposure to tobacco smoke: A report of the surgeon general-executive summary. U.S. department of health and human services, centers for disease control and prevention, coordination center for health promotion national center for chronic disease prevention and health promotion, office on smoking and health, 2006.
    • (2006)
  • 34
    • 33847771467 scopus 로고    scopus 로고
    • Transport and deposition of micro-aerosols in realistic and simplified models of the oral airway
    • Xi J., Longest P.W. Transport and deposition of micro-aerosols in realistic and simplified models of the oral airway. Annu. Biomed. Eng. 2007, 35(4):560-581.
    • (2007) Annu. Biomed. Eng. , vol.35 , Issue.4 , pp. 560-581
    • Xi, J.1    Longest, P.W.2
  • 35
    • 0029825339 scopus 로고    scopus 로고
    • Assessment of regional deposition of inhaled particles in human lungs by serial bolus delivery method
    • Kim Ch.S., Hu S.C., Dewitt P., Gerrity T.R. Assessment of regional deposition of inhaled particles in human lungs by serial bolus delivery method. J. Appl. Physiol. 1996, 81:2203-2213.
    • (1996) J. Appl. Physiol. , vol.81 , pp. 2203-2213
    • Kim, C.1    Hu, S.C.2    Dewitt, P.3    Gerrity, T.R.4
  • 38
    • 0001460459 scopus 로고
    • Diffusional deposition of ultrafine aerosols in a human nasal cast
    • Cheng Y.S., Yamada Y., Yeh H.C., Swift D.L. Diffusional deposition of ultrafine aerosols in a human nasal cast. J. Aerosol Sci. 1988, 19:741.
    • (1988) J. Aerosol Sci. , vol.19 , pp. 741
    • Cheng, Y.S.1    Yamada, Y.2    Yeh, H.C.3    Swift, D.L.4
  • 39
    • 78650607389 scopus 로고    scopus 로고
    • Effects of surface smoothness on inertial particle deposition in human nasal models
    • Schroeter J.D., Garcia G.J.M., Kimbell J.S. Effects of surface smoothness on inertial particle deposition in human nasal models. J. Aerosol Sci. 2011, 42:52-63.
    • (2011) J. Aerosol Sci. , vol.42 , pp. 52-63
    • Schroeter, J.D.1    Garcia, G.J.M.2    Kimbell, J.S.3
  • 40
    • 79955974555 scopus 로고    scopus 로고
    • In vitro deposition measurement of inhaled micrometer-sized particles in extrathoracic airways of children and adolescents during nose breathing, doi:10.1016/j.jaerosci.2011.04.002
    • L. Golshahi, M.L. Noga, R.B. Thompson, W.H. Finlay, In vitro deposition measurement of inhaled micrometer-sized particles in extrathoracic airways of children and adolescents during nose breathing, J. Aerosol Sci. doi:10.1016/j.jaerosci.2011.04.002.
    • J. Aerosol Sci.
    • Golshahi, L.1    Noga, M.L.2    Thompson, R.B.3    Finlay, W.H.4
  • 41
    • 0001575722 scopus 로고
    • The deposition of aerosol particles in the nasopharyngeal region of the human respiratory tract
    • Hounam R.F., Black A., Walsh M. The deposition of aerosol particles in the nasopharyngeal region of the human respiratory tract. J. Aerosol Sci. 1971, 2:47-61.
    • (1971) J. Aerosol Sci. , vol.2 , pp. 47-61
    • Hounam, R.F.1    Black, A.2    Walsh, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.