Emodin induces cytotoxic effect in human breast carcinoma MCF-7 cell through modulating the expression of apoptosis-related genes

Pharmaceutical Biology

Volumn 51, Issue 9, 2013, Pages 1175-1181

  Li, Wing Yan ^a   Chan, Robbie Yat Kan ^b   Yu, Peter Hoi Fu ^a,c   Chan, Shun Wan ^a,c  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b BNU HKBU UNITED INTERNATIONAL COLLEGE   (China)

^c State Key Laboratory of Chinese Medicine and Molecular Pharmacology   (China)

Author keywords

Anthraquinone; Cell cycle arrest; Growth inhibition; Programmed cell death

Indexed keywords

CYCLIN D1; EMODIN; FAS LIGAND; PROTEIN MCL 1;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN MCF 7; COLONY FORMATION; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYCLIN D1 GENE; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG MECHANISM; FAS LIGAND GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MCL1 GENE; MITOSIS INHIBITION; NUCLEOTIDE SEQUENCE; ONCOGENE C MYC; REAL TIME POLYMERASE CHAIN REACTION; SINGLE STRANDED DNA BREAK;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BREAST NEOPLASMS; CARCINOMA; CATHARTICS; CELL PROLIFERATION; CYCLIN D1; DNA BREAKS, SINGLE-STRANDED; DNA FRAGMENTATION; EMODIN; FAS LIGAND PROTEIN; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INHIBITORY CONCENTRATION 50; MCF-7 CELLS; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; NEOPLASTIC STEM CELLS; PROTO-ONCOGENE PROTEINS C-MYC;

EID: 84882294417     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2013.782322     Document Type: Article

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