To live or die - A cell's choice

Essays in Biochemistry

Volumn 37, Issue , 2001, Pages 109-120

  Link, Martyn ^a   Harrison, David J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ANIMAL; APOPTOSIS; BIOLOGICAL MODEL; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; REVIEW; SIGNAL TRANSDUCTION;

ANIMAL; APOPTOSIS; GENE EXPRESSION REGULATION; HUMAN; MODELS, BIOLOGICAL; PROTEIN P53; SIGNAL TRANSDUCTION;

EID: 0035542557     PISSN: 00711365     EISSN: None     Source Type: Journal    
DOI: 10.1042/bse0370109     Document Type: Article

References (25)

1. Hengartner, M.O., Ellis, R.E. & Horvitz, H.R. (1992) C. elgans gene ced-9 protects cells from programmed cell death. Nature (London) 356, 494-499
2. Vaux, D.L., Weissman, I.L. & Kim, S.K. (1992) Prevention of programmed cell death in C. elegans by human bcl-2. Science 258, 1955-1957
3. Amundson, S.A., Myers, T.G. & Fornace, Jr, A.J. (1998) Roles for p53 in growth arrest and apoptosis: putting the breaks on after genotoxic stress. Oncogene 17, 3287-3299
4. Thompson, B.E. (1998) The many roles of c-Myc in apoptosis. Annu. Rev. Physiol. 60, 575-600
5. Prives, C. & Hall, P.A. (1999) The p53 pathway. J. Pathol. 187, 112-126
6. Giaccia, A.J. & Kastan, M.B. (1998) The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev. 12, 2973-2983
7. Hengstschlager, M., Holzl, G. & Hengstschlager-Ottnad, E. (1999) Different regulation of c-Myc and E2F-1-induced apoptosis during the ongoing cell cycle. Oncogene 18, 843-848
8. Shan, B. & Lee, W.H. (1994) Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cell. Biol. 14, 8166-8176
9. MacLeod, K.F., Hu, Y. & Jacks, T. (1996) Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO J. 15, 6178-6188
10. Spyridopolous, I., Principe, N., Krasinski, K.L., Shu-hua, X., Kearney, M., Magner, M., Isner, J.M. & Losordo, D.W. (1998) Restoration of E2F expression rescues vascular endothelial cells from TNFa-induced apoptosis. Circulation 98, 2883-2890
11. Field, S.J., Tsai, F.Y., Kuo, F., Zubiaga, A.M., Kaelin, Jr, W.G., Livingston, D.M., Orkin, S.H. & Greenberg, M.E. (1996) E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell 85, 549-561
12. Hoffman, B. & Liebermann, D.A. (1998) The proto-oncogene c-myc and apoptosis. Oncogene 17, 3351-3357
13. Evan, G.I., Wyllie, A.M., Gilbert, C.S., Littlewood, T.D., Land, H., Brooks, M., Waters, C.M., Penn, L.Z. & Hancock, D.C. (1992) Induction of apoptosis in fibroblasts by c-Myc protein. Cell 69, 119-128
14. Sakamuro, D., Eviner, V., Showe, L., White, E. & Predergast, G.C. (1995) c-Myc induces apoptosis in epithelial cells by both p53-dependent and p53-independent mechanisms. Oncogene 11, 2411-2418
15. Reed, J.C. (1998) Bcl-2 family proteins. Oncogene 17, 3225-3236
16. Mizuno, N., Yoshitomi, H., Ishida, H., Kuromi, H., Kawaki, J., Seino, Y. & Seino, S. (1998) Altered bcl-2 and bax expression and intracellular calcium signalling in apoptosis of pancreatic cells and the impairment of glucose-induced insulin secretion. Endocrinology 139, 1429-1439
17. 2: senescence-like growth arrest or apoptosis? Cell Growth Differ. 8, 589-598
18. McCarthy, N.J., Whyte, M.K., Gilbert, C.S. & Evan, G.I. (1997) Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage or the Bcl-2 homologue Bak. J. Cell Biol. 136, 215-227
19. Sun, X.-M., MacFarlane, M., Zhuang, J., Wolf, B.B., Green, D.R. & Cohen, G.M. (1999) Distinct chemical cascades are initiated in receptor-mediated and chemical-induced apoptosis. J. Biol. Chem. 274, 5053-5060
20. Hammill, A.K., Uhr, J.W. & Scheuermann, R.H. (1999) Annexin V staining due to loss of membrane asymmetry can be reversible and precede commitment to apoptotic death. Exp. Cell Res. 251, 16-21
21. Harvey, K.J., Blomquist, J.F. & Ucker, D.S. (1998) Commitment and effector phases of the physiological cell death pathway elucidated with respect to Bcl-2, caspase and cyclin-dependent kinase activities. Mol. Cell. Biol. 18, 2912-2922
22. Dragovich, T., Rudin, C.M. & Thompson, C.B. (1998) Signal transduction pathways that regulate cell survival and cell death. Oncogene 17, 3207-3213
23. Nunez, G., Benedict, M.A., Yuanming, H. & Inohara, N. (1998) Caspases: the proteases of the apoptotic pathway. Oncogene 17, 3237-3245
24. Green, D.R. & Amarante-Mendes, G.P. (1998) The point of no return: mitochondria, caspases and the commitment to cell death. Results Probl. Cell Differ. 24, 45-61
25. Scorrano, L., Petronilli, V., Lisa, F.D. & Bernardi, P. (1999) Commitment to apoptosis by GD3 ganglioside depends on opening of the mitochondrial permeability transition pore. J. Biol. Chem. 274, 22581-22585