A novel small-molecule thienoquinolin urea transporter inhibitor acts as a potential diuretic

Kidney International

Volumn 83, Issue 6, 2013, Pages 1076-1086

  Li, Fei ^a,b   Lei, Tianluo ^a,b   Zhu, Juanjuan ^a,b   Wang, Weiling ^a,b   Sun, Yi ^a,b   Chen, Jihui ^a,b   Dong, Zixun ^a,b   Zhou, Hong ^a,b   Yang, Baoxue ^a,b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

Diuretics; Electrolytes; Physiology; Renal; Urea; Water electrolyte balance

Indexed keywords

1 (3 AMINO 6 METHYLTHIENO[2,3 B]QUINOLIN 2 YL)ETHANONE; DIURETIC AGENT; HYDROCHLOROTHIAZIDE; MEMBRANE PROTEIN; PU 14; THIENOQUINOLIN DERIVATIVE; UNCLASSIFIED DRUG; UREA; UREA TRANSPORTER A; UREA TRANSPORTER B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIURETIC ACTIVITY; DRUG EFFICACY; DRUG SCREENING; DRUG STRUCTURE; ELECTROLYTE METABOLISM; ERYTHROCYTE; HUMAN; HUMAN CELL; KIDNEY CLEARANCE; KIDNEY CONCENTRATING CAPACITY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RABBIT; RAT; STRUCTURE ACTIVITY RELATION; URINE OSMOLALITY; URINE VOLUME; WATER METABOLISM;

EID: 84882284543     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.62     Document Type: Article

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