-
2
-
-
0344688272
-
Tau phosphorylation, tangles, and neurodegeneration: The chicken or the egg?
-
D.H. Geschwind Tau phosphorylation, tangles, and neurodegeneration: the chicken or the egg? Neuron 40 2003 457 460
-
(2003)
Neuron
, vol.40
, pp. 457-460
-
-
Geschwind, D.H.1
-
5
-
-
0034996076
-
Microglial activation parallels system degeneration in progressive supranuclear palsy and corticobasal degeneration
-
K. Ishizawa, and D.W. Dickson Microglial activation parallels system degeneration in progressive supranuclear palsy and corticobasal degeneration J Neuropathol Exp Neurol 60 2001 647 657
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 647-657
-
-
Ishizawa, K.1
Dickson, D.W.2
-
6
-
-
25644456097
-
Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5 mediated pathways in a transgenic model of Alzheimer's disease
-
M. Kitazawa, S. Oddo, T.R. Yamasaki, K.N. Green, and F. Laferla Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5 mediated pathways in a transgenic model of Alzheimer's disease J Neurosci 25 2005 8843 8853
-
(2005)
J Neurosci
, vol.25
, pp. 8843-8853
-
-
Kitazawa, M.1
Oddo, S.2
Yamasaki, T.R.3
Green, K.N.4
Laferla, F.5
-
7
-
-
77957321869
-
Regulation of tau pathology by microglial fractalkine receptor
-
K. Bhaskar, M. Konerth, O. Kokiko-Cochran, A. Cardona, R. Ransohoff, and B. Lamb Regulation of tau pathology by microglial fractalkine receptor Neuron 68 2010 19 31
-
(2010)
Neuron
, vol.68
, pp. 19-31
-
-
Bhaskar, K.1
Konerth, M.2
Kokiko-Cochran, O.3
Cardona, A.4
Ransohoff, R.5
Lamb, B.6
-
8
-
-
33846538660
-
Synapse loss and microglial activation precede tangle in a P301S tauopathy mouse model
-
Y. Yoshima, M. Higuchi, B. Zhang, S.M. Huang, N. Iwata, and T.C. Saido Synapse loss and microglial activation precede tangle in a P301S tauopathy mouse model Neuron 53 2007 337 351
-
(2007)
Neuron
, vol.53
, pp. 337-351
-
-
Yoshima, Y.1
Higuchi, M.2
Zhang, B.3
Huang, S.M.4
Iwata, N.5
Saido, T.C.6
-
9
-
-
34447565153
-
The 5-Lipoxygenase enzymatic pathways in the mouse brain: Young versus old
-
C. Chinnici, Y. Yao, and D. Praticò The 5-Lipoxygenase enzymatic pathways in the mouse brain: Young versus old Neurobiol Aging 28 2007 1457 1462
-
(2007)
Neurobiol Aging
, vol.28
, pp. 1457-1462
-
-
Chinnici, C.1
Yao, Y.2
Praticò, D.3
-
10
-
-
56449106689
-
Increased 5-lipoxygenase immunoreactivity in hippocampus of patients with Alzheimer's disease
-
M.D. Ikonomovic, E.E. Abrahamson, T. Uz, H. Manev, and S.T. Dekosky Increased 5-lipoxygenase immunoreactivity in hippocampus of patients with Alzheimer's disease J Histochem Cytochem 56 2008 1065 1073
-
(2008)
J Histochem Cytochem
, vol.56
, pp. 1065-1073
-
-
Ikonomovic, M.D.1
Abrahamson, E.E.2
Uz, T.3
Manev, H.4
Dekosky, S.T.5
-
11
-
-
42049114647
-
5-Lipoxygenase gene disruption reduces amyloid-{beta} pathology in a mouse model of Alzheimer's disease
-
O. Firuzi, J. Zhou, C.M. Chinnici, T. Wisnieski, and D. Praticò 5-Lipoxygenase gene disruption reduces amyloid-{beta} pathology in a mouse model of Alzheimer's disease FASEB J 22 2008 1169 1178
-
(2008)
FASEB J
, vol.22
, pp. 1169-1178
-
-
Firuzi, O.1
Zhou, J.2
Chinnici, C.M.3
Wisnieski, T.4
Praticò, D.5
-
12
-
-
79953660461
-
Pharmacologic blockade of 5-Lipoxygenase improves the amyloidotic phenotype of an AD transgenic mouse model: Involvement of γ-secretase
-
J. Chu, and D. Pratico Pharmacologic blockade of 5-Lipoxygenase improves the amyloidotic phenotype of an AD transgenic mouse model: Involvement of γ-secretase Am J Pathol 178 2011 1762 1769
-
(2011)
Am J Pathol
, vol.178
, pp. 1762-1769
-
-
Chu, J.1
Pratico, D.2
-
13
-
-
84855414647
-
Adeno-associated virus-mediated brain delivery of 5-Lipoxygenase modulates the AD-like phenotype of APP mice
-
J. Chu, P.J. Giannopoulos, C. Ceballos-Diaz, T. Golde, and D. Pratico Adeno-associated virus-mediated brain delivery of 5-Lipoxygenase modulates the AD-like phenotype of APP mice Mol Neurodegen 7 2012 1
-
(2012)
Mol Neurodegen
, vol.7
, pp. 1
-
-
Chu, J.1
Giannopoulos, P.J.2
Ceballos-Diaz, C.3
Golde, T.4
Pratico, D.5
-
14
-
-
33751111439
-
Intracranial adeno-associated virus mediated delivery of antipan amylodi Aβ, amyloid β40, and amyloid β42 single-chain variable fragments attenuates plaque pathology in amyloid precursor protein mice
-
Y. Levites, K. Jansen, L.A. Smithson, R. Dakin, V.M. Holloway, P. Das, and T.E. Golde Intracranial adeno-associated virus mediated delivery of antipan amylodi Aβ, amyloid β40, and amyloid β42 single-chain variable fragments attenuates plaque pathology in amyloid precursor protein mice J Neurosci 26 2006 11923 11928
-
(2006)
J Neurosci
, vol.26
, pp. 11923-11928
-
-
Levites, Y.1
Jansen, K.2
Smithson, L.A.3
Dakin, R.4
Holloway, V.M.5
Das, P.6
Golde, T.E.7
-
15
-
-
44949217679
-
BRI2(ITM2b) inhibits Abeta deposition in vivo
-
J. Kim, V.M. Miller, Y. Levites, K. Jansen West, G.W. Zwiziski, and B.D. Moore BRI2(ITM2b) inhibits Abeta deposition in vivo J Neurosci 28 2008 6030 6036
-
(2008)
J Neurosci
, vol.28
, pp. 6030-6036
-
-
Kim, J.1
Miller, V.M.2
Levites, Y.3
Jansen West, K.4
Zwiziski, G.W.5
Moore, B.D.6
-
16
-
-
0041803006
-
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
-
C. Andorfer, Y. Kress, M. Espinoza, R. de Silva, K.L. Tucker, and Y. Barde Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms J Neurochem 86 2003 582 590
-
(2003)
J Neurochem
, vol.86
, pp. 582-590
-
-
Andorfer, C.1
Kress, Y.2
Espinoza, M.3
De Silva, R.4
Tucker, K.L.5
Barde, Y.6
-
17
-
-
84863887275
-
Stress hormone leads to memory deficits and altered tau phosphorylation in a mouse model of Alzheimer's disease
-
Y. Joshi, J. Chu, and D. Pratico Stress hormone leads to memory deficits and altered tau phosphorylation in a mouse model of Alzheimer's disease J Alz Dis 31 2012 167 176
-
(2012)
J Alz Dis
, vol.31
, pp. 167-176
-
-
Joshi, Y.1
Chu, J.2
Pratico, D.3
-
18
-
-
65649098041
-
An immunohistochemical study of GABA receptor gamma subunits in Alzheimer's disease hippocampus: Relationship to neurofibrillary tangle progression
-
M. Iwakiri, K. Mizukami, M. Ikonomovic, M. Ishikawa, E. Abrahamson, S. Dekosky, and T. Asada An immunohistochemical study of GABA receptor gamma subunits in Alzheimer's disease hippocampus: Relationship to neurofibrillary tangle progression Neuropathology 29 2009 263 269
-
(2009)
Neuropathology
, vol.29
, pp. 263-269
-
-
Iwakiri, M.1
Mizukami, K.2
Ikonomovic, M.3
Ishikawa, M.4
Abrahamson, E.5
Dekosky, S.6
Asada, T.7
-
19
-
-
55249086251
-
Hyperphosphorylation of microtubule-associated protein tau: A promising therapeutic target for Alzheimer disease
-
C.X. Gong, and K. Iqbal Hyperphosphorylation of microtubule-associated protein tau: A promising therapeutic target for Alzheimer disease Curr Med Chem 15 2008 2321 2328
-
(2008)
Curr Med Chem
, vol.15
, pp. 2321-2328
-
-
Gong, C.X.1
Iqbal, K.2
-
20
-
-
70449336472
-
Five lipoxygenase activating protein inhibitors for the treatment of inflammatory disease
-
A.P. Sampson Five lipoxygenase activating protein inhibitors for the treatment of inflammatory disease Curr Opin Investig Drugs 10 2009 1163 1172
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 1163-1172
-
-
Sampson, A.P.1
-
21
-
-
0034991806
-
5-Lipoxygenase (5-LOX) promoter polymorphism in patients with early-onset and late-onset Alzheimer's disease
-
T. Qu, R. Manev, and H. Manev 5-Lipoxygenase (5-LOX) promoter polymorphism in patients with early-onset and late-onset Alzheimer's disease J Neuropsychiatry Clin Neurosci 13 2001 304 305
-
(2001)
J Neuropsychiatry Clin Neurosci
, vol.13
, pp. 304-305
-
-
Qu, T.1
Manev, R.2
Manev, H.3
-
22
-
-
84867095666
-
5-Lipoxygenase gene transfer worsens memory, amyloid and tau brain pathologies in a mouse model of Alzheimer disease
-
J. Chu, P.J. Giannopoulos, C. Ceballos-Diaz, T. Golde, and D. Pratico 5-Lipoxygenase gene transfer worsens memory, amyloid and tau brain pathologies in a mouse model of Alzheimer disease Ann Neurol 72 2012 442 454
-
(2012)
Ann Neurol
, vol.72
, pp. 442-454
-
-
Chu, J.1
Giannopoulos, P.J.2
Ceballos-Diaz, C.3
Golde, T.4
Pratico, D.5
-
23
-
-
79952105548
-
Post-translational modifications of tau protein: Implications for Alzheimer's disease
-
L. Martin, X. Latypova, and F. Terro Post-translational modifications of tau protein: Implications for Alzheimer's disease Neurochem Int 58 2011 458 471
-
(2011)
Neurochem Int
, vol.58
, pp. 458-471
-
-
Martin, L.1
Latypova, X.2
Terro, F.3
-
24
-
-
0035208849
-
Activation of JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis
-
C. Atzori, B. Ghetti, R. Piva, A.N. Srinivasan, P. Zolo, and M.B. Delisle Activation of JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis J Neuropathol Exp Neurol 60 2001 1190 1197
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 1190-1197
-
-
Atzori, C.1
Ghetti, B.2
Piva, R.3
Srinivasan, A.N.4
Zolo, P.5
Delisle, M.B.6
-
25
-
-
0036580703
-
Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition
-
M.J. Savage, Y.G. Lin, J.R. Ciallela, D.G. Flood, and R.W. Scott Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition J Neurosci 22 2002 3376 3385
-
(2002)
J Neurosci
, vol.22
, pp. 3376-3385
-
-
Savage, M.J.1
Lin, Y.G.2
Ciallela, J.R.3
Flood, D.G.4
Scott, R.W.5
-
26
-
-
0037023679
-
Glycogen synthase kinase-beta is complexed with tau protein in brain microtubules
-
W. Sun, H.Y. Qureshi, P.W. Cafferty, K. Sobue, A. Agarwal-Mawal, K.D. Neufield, and H.K. Paudel Glycogen synthase kinase-beta is complexed with tau protein in brain microtubules J Biol Chem 277 2002 11933 11940
-
(2002)
J Biol Chem
, vol.277
, pp. 11933-11940
-
-
Sun, W.1
Qureshi, H.Y.2
Cafferty, P.W.3
Sobue, K.4
Agarwal-Mawal, A.5
Neufield, K.D.6
Paudel, H.K.7
-
27
-
-
0346434153
-
Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory
-
S.J. Liu, A.H. Zhang, H.L. Li, Q. Wang, H.M. Deng, and W.J. Netzer Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory J Neurochem 87 2003 1333 1344
-
(2003)
J Neurochem
, vol.87
, pp. 1333-1344
-
-
Liu, S.J.1
Zhang, A.H.2
Li, H.L.3
Wang, Q.4
Deng, H.M.5
Netzer, W.J.6
-
28
-
-
0038030381
-
P39 activates cdk5 in neurons, and is associated with the actin cytoskeleton
-
S. Humbert, R. Dhavan, and L. Tsai p39 activates cdk5 in neurons, and is associated with the actin cytoskeleton J Cell Sci 113 2000 975 983
-
(2000)
J Cell Sci
, vol.113
, pp. 975-983
-
-
Humbert, S.1
Dhavan, R.2
Tsai, L.3
-
29
-
-
0038705066
-
Cdk5: One of the links between senile plaques and neurofibrillary tangles?
-
M.S. Lee, and L.H. Tsai Cdk5: One of the links between senile plaques and neurofibrillary tangles? J Alz Dis 5 2003 127 137
-
(2003)
J Alz Dis
, vol.5
, pp. 127-137
-
-
Lee, M.S.1
Tsai, L.H.2
-
30
-
-
84862813753
-
Amelioration of social isolation-triggered onset of early Alzheimer's disease-related cognitive deficit by N-acetylcysteine in a transgenic mouse model
-
Y.H. Hsiao, J.R. Kuo, S.H. Chen, and P.W. Gean Amelioration of social isolation-triggered onset of early Alzheimer's disease-related cognitive deficit by N-acetylcysteine in a transgenic mouse model Neurobiol Dis 45 2012 1111 1120
-
(2012)
Neurobiol Dis
, vol.45
, pp. 1111-1120
-
-
Hsiao, Y.H.1
Kuo, J.R.2
Chen, S.H.3
Gean, P.W.4
-
31
-
-
34147094108
-
5-Lipoxygenase inhibitor MK-886 increases GluR1 phosphorylation in neuronal cultures in vitro and in the mouse cortex in vivo
-
M. Imbesi, I. Zavoreo, T. Uz, R.P. Sharma, N. Dimitrijevic, H. Manev, and R. Manev 5-Lipoxygenase inhibitor MK-886 increases GluR1 phosphorylation in neuronal cultures in vitro and in the mouse cortex in vivo Brain Res 1147 2007 148 153
-
(2007)
Brain Res
, vol.1147
, pp. 148-153
-
-
Imbesi, M.1
Zavoreo, I.2
Uz, T.3
Sharma, R.P.4
Dimitrijevic, N.5
Manev, H.6
Manev, R.7
|