메뉴 건너뛰기




Volumn 74, Issue 5, 2013, Pages 321-328

The influence of 5-lipoxygenase on Alzheimer's disease-related tau pathology: In vivo and in vitro evidence

Author keywords

5 Lipoxygenase; Alzheimer's disease; amyloid beta; cyclin dependent kinase 5; tau protein; transgenic mouse model

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; CYCLIN DEPENDENT KINASE 5; MICROTUBULE ASSOCIATED PROTEIN 2; POSTSYNAPTIC DENSITY PROTEIN 95; SYNAPTOPHYSIN; TAU PROTEIN;

EID: 84882256181     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2012.12.012     Document Type: Article
Times cited : (27)

References (31)
  • 2
    • 0344688272 scopus 로고    scopus 로고
    • Tau phosphorylation, tangles, and neurodegeneration: The chicken or the egg?
    • D.H. Geschwind Tau phosphorylation, tangles, and neurodegeneration: the chicken or the egg? Neuron 40 2003 457 460
    • (2003) Neuron , vol.40 , pp. 457-460
    • Geschwind, D.H.1
  • 3
  • 4
    • 80053212816 scopus 로고    scopus 로고
    • The role of tau in Alzheimer's disease and related disorders
    • R. Mederios, D. Baglietto-Vargas, and F. Laferla The role of tau in Alzheimer's disease and related disorders CNS Neurosci Ther 17 2011 514 524
    • (2011) CNS Neurosci Ther , vol.17 , pp. 514-524
    • Mederios, R.1    Baglietto-Vargas, D.2    Laferla, F.3
  • 5
    • 0034996076 scopus 로고    scopus 로고
    • Microglial activation parallels system degeneration in progressive supranuclear palsy and corticobasal degeneration
    • K. Ishizawa, and D.W. Dickson Microglial activation parallels system degeneration in progressive supranuclear palsy and corticobasal degeneration J Neuropathol Exp Neurol 60 2001 647 657
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 647-657
    • Ishizawa, K.1    Dickson, D.W.2
  • 6
    • 25644456097 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5 mediated pathways in a transgenic model of Alzheimer's disease
    • M. Kitazawa, S. Oddo, T.R. Yamasaki, K.N. Green, and F. Laferla Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5 mediated pathways in a transgenic model of Alzheimer's disease J Neurosci 25 2005 8843 8853
    • (2005) J Neurosci , vol.25 , pp. 8843-8853
    • Kitazawa, M.1    Oddo, S.2    Yamasaki, T.R.3    Green, K.N.4    Laferla, F.5
  • 8
    • 33846538660 scopus 로고    scopus 로고
    • Synapse loss and microglial activation precede tangle in a P301S tauopathy mouse model
    • Y. Yoshima, M. Higuchi, B. Zhang, S.M. Huang, N. Iwata, and T.C. Saido Synapse loss and microglial activation precede tangle in a P301S tauopathy mouse model Neuron 53 2007 337 351
    • (2007) Neuron , vol.53 , pp. 337-351
    • Yoshima, Y.1    Higuchi, M.2    Zhang, B.3    Huang, S.M.4    Iwata, N.5    Saido, T.C.6
  • 9
    • 34447565153 scopus 로고    scopus 로고
    • The 5-Lipoxygenase enzymatic pathways in the mouse brain: Young versus old
    • C. Chinnici, Y. Yao, and D. Praticò The 5-Lipoxygenase enzymatic pathways in the mouse brain: Young versus old Neurobiol Aging 28 2007 1457 1462
    • (2007) Neurobiol Aging , vol.28 , pp. 1457-1462
    • Chinnici, C.1    Yao, Y.2    Praticò, D.3
  • 10
    • 56449106689 scopus 로고    scopus 로고
    • Increased 5-lipoxygenase immunoreactivity in hippocampus of patients with Alzheimer's disease
    • M.D. Ikonomovic, E.E. Abrahamson, T. Uz, H. Manev, and S.T. Dekosky Increased 5-lipoxygenase immunoreactivity in hippocampus of patients with Alzheimer's disease J Histochem Cytochem 56 2008 1065 1073
    • (2008) J Histochem Cytochem , vol.56 , pp. 1065-1073
    • Ikonomovic, M.D.1    Abrahamson, E.E.2    Uz, T.3    Manev, H.4    Dekosky, S.T.5
  • 11
    • 42049114647 scopus 로고    scopus 로고
    • 5-Lipoxygenase gene disruption reduces amyloid-{beta} pathology in a mouse model of Alzheimer's disease
    • O. Firuzi, J. Zhou, C.M. Chinnici, T. Wisnieski, and D. Praticò 5-Lipoxygenase gene disruption reduces amyloid-{beta} pathology in a mouse model of Alzheimer's disease FASEB J 22 2008 1169 1178
    • (2008) FASEB J , vol.22 , pp. 1169-1178
    • Firuzi, O.1    Zhou, J.2    Chinnici, C.M.3    Wisnieski, T.4    Praticò, D.5
  • 12
    • 79953660461 scopus 로고    scopus 로고
    • Pharmacologic blockade of 5-Lipoxygenase improves the amyloidotic phenotype of an AD transgenic mouse model: Involvement of γ-secretase
    • J. Chu, and D. Pratico Pharmacologic blockade of 5-Lipoxygenase improves the amyloidotic phenotype of an AD transgenic mouse model: Involvement of γ-secretase Am J Pathol 178 2011 1762 1769
    • (2011) Am J Pathol , vol.178 , pp. 1762-1769
    • Chu, J.1    Pratico, D.2
  • 13
    • 84855414647 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated brain delivery of 5-Lipoxygenase modulates the AD-like phenotype of APP mice
    • J. Chu, P.J. Giannopoulos, C. Ceballos-Diaz, T. Golde, and D. Pratico Adeno-associated virus-mediated brain delivery of 5-Lipoxygenase modulates the AD-like phenotype of APP mice Mol Neurodegen 7 2012 1
    • (2012) Mol Neurodegen , vol.7 , pp. 1
    • Chu, J.1    Giannopoulos, P.J.2    Ceballos-Diaz, C.3    Golde, T.4    Pratico, D.5
  • 14
    • 33751111439 scopus 로고    scopus 로고
    • Intracranial adeno-associated virus mediated delivery of antipan amylodi Aβ, amyloid β40, and amyloid β42 single-chain variable fragments attenuates plaque pathology in amyloid precursor protein mice
    • Y. Levites, K. Jansen, L.A. Smithson, R. Dakin, V.M. Holloway, P. Das, and T.E. Golde Intracranial adeno-associated virus mediated delivery of antipan amylodi Aβ, amyloid β40, and amyloid β42 single-chain variable fragments attenuates plaque pathology in amyloid precursor protein mice J Neurosci 26 2006 11923 11928
    • (2006) J Neurosci , vol.26 , pp. 11923-11928
    • Levites, Y.1    Jansen, K.2    Smithson, L.A.3    Dakin, R.4    Holloway, V.M.5    Das, P.6    Golde, T.E.7
  • 16
    • 0041803006 scopus 로고    scopus 로고
    • Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
    • C. Andorfer, Y. Kress, M. Espinoza, R. de Silva, K.L. Tucker, and Y. Barde Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms J Neurochem 86 2003 582 590
    • (2003) J Neurochem , vol.86 , pp. 582-590
    • Andorfer, C.1    Kress, Y.2    Espinoza, M.3    De Silva, R.4    Tucker, K.L.5    Barde, Y.6
  • 17
    • 84863887275 scopus 로고    scopus 로고
    • Stress hormone leads to memory deficits and altered tau phosphorylation in a mouse model of Alzheimer's disease
    • Y. Joshi, J. Chu, and D. Pratico Stress hormone leads to memory deficits and altered tau phosphorylation in a mouse model of Alzheimer's disease J Alz Dis 31 2012 167 176
    • (2012) J Alz Dis , vol.31 , pp. 167-176
    • Joshi, Y.1    Chu, J.2    Pratico, D.3
  • 18
    • 65649098041 scopus 로고    scopus 로고
    • An immunohistochemical study of GABA receptor gamma subunits in Alzheimer's disease hippocampus: Relationship to neurofibrillary tangle progression
    • M. Iwakiri, K. Mizukami, M. Ikonomovic, M. Ishikawa, E. Abrahamson, S. Dekosky, and T. Asada An immunohistochemical study of GABA receptor gamma subunits in Alzheimer's disease hippocampus: Relationship to neurofibrillary tangle progression Neuropathology 29 2009 263 269
    • (2009) Neuropathology , vol.29 , pp. 263-269
    • Iwakiri, M.1    Mizukami, K.2    Ikonomovic, M.3    Ishikawa, M.4    Abrahamson, E.5    Dekosky, S.6    Asada, T.7
  • 19
    • 55249086251 scopus 로고    scopus 로고
    • Hyperphosphorylation of microtubule-associated protein tau: A promising therapeutic target for Alzheimer disease
    • C.X. Gong, and K. Iqbal Hyperphosphorylation of microtubule-associated protein tau: A promising therapeutic target for Alzheimer disease Curr Med Chem 15 2008 2321 2328
    • (2008) Curr Med Chem , vol.15 , pp. 2321-2328
    • Gong, C.X.1    Iqbal, K.2
  • 20
    • 70449336472 scopus 로고    scopus 로고
    • Five lipoxygenase activating protein inhibitors for the treatment of inflammatory disease
    • A.P. Sampson Five lipoxygenase activating protein inhibitors for the treatment of inflammatory disease Curr Opin Investig Drugs 10 2009 1163 1172
    • (2009) Curr Opin Investig Drugs , vol.10 , pp. 1163-1172
    • Sampson, A.P.1
  • 21
    • 0034991806 scopus 로고    scopus 로고
    • 5-Lipoxygenase (5-LOX) promoter polymorphism in patients with early-onset and late-onset Alzheimer's disease
    • T. Qu, R. Manev, and H. Manev 5-Lipoxygenase (5-LOX) promoter polymorphism in patients with early-onset and late-onset Alzheimer's disease J Neuropsychiatry Clin Neurosci 13 2001 304 305
    • (2001) J Neuropsychiatry Clin Neurosci , vol.13 , pp. 304-305
    • Qu, T.1    Manev, R.2    Manev, H.3
  • 22
    • 84867095666 scopus 로고    scopus 로고
    • 5-Lipoxygenase gene transfer worsens memory, amyloid and tau brain pathologies in a mouse model of Alzheimer disease
    • J. Chu, P.J. Giannopoulos, C. Ceballos-Diaz, T. Golde, and D. Pratico 5-Lipoxygenase gene transfer worsens memory, amyloid and tau brain pathologies in a mouse model of Alzheimer disease Ann Neurol 72 2012 442 454
    • (2012) Ann Neurol , vol.72 , pp. 442-454
    • Chu, J.1    Giannopoulos, P.J.2    Ceballos-Diaz, C.3    Golde, T.4    Pratico, D.5
  • 23
    • 79952105548 scopus 로고    scopus 로고
    • Post-translational modifications of tau protein: Implications for Alzheimer's disease
    • L. Martin, X. Latypova, and F. Terro Post-translational modifications of tau protein: Implications for Alzheimer's disease Neurochem Int 58 2011 458 471
    • (2011) Neurochem Int , vol.58 , pp. 458-471
    • Martin, L.1    Latypova, X.2    Terro, F.3
  • 24
    • 0035208849 scopus 로고    scopus 로고
    • Activation of JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis
    • C. Atzori, B. Ghetti, R. Piva, A.N. Srinivasan, P. Zolo, and M.B. Delisle Activation of JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis J Neuropathol Exp Neurol 60 2001 1190 1197
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 1190-1197
    • Atzori, C.1    Ghetti, B.2    Piva, R.3    Srinivasan, A.N.4    Zolo, P.5    Delisle, M.B.6
  • 25
    • 0036580703 scopus 로고    scopus 로고
    • Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition
    • M.J. Savage, Y.G. Lin, J.R. Ciallela, D.G. Flood, and R.W. Scott Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition J Neurosci 22 2002 3376 3385
    • (2002) J Neurosci , vol.22 , pp. 3376-3385
    • Savage, M.J.1    Lin, Y.G.2    Ciallela, J.R.3    Flood, D.G.4    Scott, R.W.5
  • 27
    • 0346434153 scopus 로고    scopus 로고
    • Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory
    • S.J. Liu, A.H. Zhang, H.L. Li, Q. Wang, H.M. Deng, and W.J. Netzer Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory J Neurochem 87 2003 1333 1344
    • (2003) J Neurochem , vol.87 , pp. 1333-1344
    • Liu, S.J.1    Zhang, A.H.2    Li, H.L.3    Wang, Q.4    Deng, H.M.5    Netzer, W.J.6
  • 28
    • 0038030381 scopus 로고    scopus 로고
    • P39 activates cdk5 in neurons, and is associated with the actin cytoskeleton
    • S. Humbert, R. Dhavan, and L. Tsai p39 activates cdk5 in neurons, and is associated with the actin cytoskeleton J Cell Sci 113 2000 975 983
    • (2000) J Cell Sci , vol.113 , pp. 975-983
    • Humbert, S.1    Dhavan, R.2    Tsai, L.3
  • 29
    • 0038705066 scopus 로고    scopus 로고
    • Cdk5: One of the links between senile plaques and neurofibrillary tangles?
    • M.S. Lee, and L.H. Tsai Cdk5: One of the links between senile plaques and neurofibrillary tangles? J Alz Dis 5 2003 127 137
    • (2003) J Alz Dis , vol.5 , pp. 127-137
    • Lee, M.S.1    Tsai, L.H.2
  • 30
    • 84862813753 scopus 로고    scopus 로고
    • Amelioration of social isolation-triggered onset of early Alzheimer's disease-related cognitive deficit by N-acetylcysteine in a transgenic mouse model
    • Y.H. Hsiao, J.R. Kuo, S.H. Chen, and P.W. Gean Amelioration of social isolation-triggered onset of early Alzheimer's disease-related cognitive deficit by N-acetylcysteine in a transgenic mouse model Neurobiol Dis 45 2012 1111 1120
    • (2012) Neurobiol Dis , vol.45 , pp. 1111-1120
    • Hsiao, Y.H.1    Kuo, J.R.2    Chen, S.H.3    Gean, P.W.4
  • 31
    • 34147094108 scopus 로고    scopus 로고
    • 5-Lipoxygenase inhibitor MK-886 increases GluR1 phosphorylation in neuronal cultures in vitro and in the mouse cortex in vivo
    • M. Imbesi, I. Zavoreo, T. Uz, R.P. Sharma, N. Dimitrijevic, H. Manev, and R. Manev 5-Lipoxygenase inhibitor MK-886 increases GluR1 phosphorylation in neuronal cultures in vitro and in the mouse cortex in vivo Brain Res 1147 2007 148 153
    • (2007) Brain Res , vol.1147 , pp. 148-153
    • Imbesi, M.1    Zavoreo, I.2    Uz, T.3    Sharma, R.P.4    Dimitrijevic, N.5    Manev, H.6    Manev, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.