Comparative pharmacokinetics of swertiamarin in rats after oral administration of swertiamarin alone, Qing Ye Dan tablets and co-administration of swertiamarin and oleanolic acid

Journal of Ethnopharmacology

Volumn 149, Issue 1, 2013, Pages 49-54

  Xu, Gui Li ^a,b   Li, Hong Liang ^b,c   He, Jian Chang ^b   Feng, En Fu ^b   Shi, Pan Pan ^b   Liu, Yue Qiong ^b   Liu, Chang Xiao ^a,b  

^a TIANJIN UNIVERSITY   (China)

^b KUNMING GENERAL HOSPITAL   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Interactions; Oleanolic acid; Pharmacokinetics; Qing Ye Dan tablet; Swertiamarin

Indexed keywords

AURANTIIN; CHINESE DRUG; OLEANOLIC ACID; QING YE DAN; SWERTIAMARIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; COMPARTMENT MODEL; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG ISOLATION; DRUG PURITY; DRUG STRUCTURE; ELECTROSPRAY; ENVIRONMENTAL TEMPERATURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MAXIMUM PLASMA CONCENTRATION; MEASUREMENT ACCURACY; NONHUMAN; PHARMACOKINETICS; QUALITY CONTROL; RAT; SIGNAL NOISE RATIO; SOLID PHASE EXTRACTION; TABLET; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION;

RATTUS;

INTERACTIONS; OLEANOLIC ACID; PHARMACOKINETICS; QING YE DAN TABLET; SWERTIAMARIN;

ADMINISTRATION, ORAL; ANIMALS; CHINA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; ETHNOPHARMACOLOGY; HERB-DRUG INTERACTIONS; IRIDOID GLUCOSIDES; MOLECULAR STRUCTURE; OLEANOLIC ACID; PYRONES; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SWERTIA; TABLETS;

EID: 84882246176     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.05.016     Document Type: Article

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