Development and validation of a LC-ESI-MS/MS method for the determination of swertiamarin in rat plasma and its application in pharmacokinetics

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 19, 2011, Pages 1653-1658

  Li, Hong Liang ^a,b   Peng, Xiao Jin ^c   He, Jian Chang ^a   Feng, En Fu ^a   Xu, Gui Li ^a,b   Rao, Gao Xiong ^c  

^a KUNMING GENERAL HOSPITAL   (China)

^b KUNMING MEDICAL UNIVERSITY   (China)

^c YUNNAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

LC ESI MS MS; Pharmacokinetics; Rat plasma; Swertiamarin

Indexed keywords

AGILENT; APPARENT VOLUME; ASSAY METHODS; BIOACTIVE SUBSTANCES; CHEMICAL STRUCTURE; FREEZE/THAW; INTERNAL DIAMETERS; INTERNAL STANDARDS; ION ELECTROSPRAY; IONISATION; LC-ESI-MS/MS; LIMIT OF DETECTION; LINEAR RANGE; LOWER LIMIT OF QUANTIFICATIONS; MOBILE PHASE; MULTIPLE-REACTION MONITORING MODES; ORAL ADMINISTRATION; PHARMACOKINETIC PARAMETERS; PHARMACOKINETIC PROPERTIES; PLASMA CONCENTRATION; RAT PLASMA; SAMPLE CLEAN-UP; SOLID-PHASE EXTRACTION; SWERTIAMARIN;

ACETIC ACID; CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; EXTRACTION; MASS SPECTROMETRY; METHANOL; PHARMACOKINETICS; PLASMA (HUMAN); PLASMAS; STANDARDIZATION;

DRUG PRODUCTS;

ACETIC ACID; GENTIOPICRIN; METHANOL; SWERTIAMARIN; WATER;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG TRAFFIC; ELECTROSPRAY; FEMALE; FLOW RATE; FREEZE THAWING; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PLASMA; PRIORITY JOURNAL; RAT; SAMPLE; SOLID; SOLID PHASE EXTRACTION; SWERTIA; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; VALIDATION STUDY;

ANIMALS; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; FEMALE; HYDROGEN-ION CONCENTRATION; IRIDOID GLUCOSIDES; LINEAR MODELS; MALE; PYRONES; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

RATTUS; SWERTIA;

EID: 79955909249     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.04.003     Document Type: Article

References (16)

1. Ma L.N., Tian C.W., Zhang T.J., Zhang L.J., Xu X.H. Chin. Tradit. Herbal Drugs 2008, 39:790.
2. Ramesh N., Viswanathan M.B., Saraswathy A., Balakrishna K., Brindha P., Lakshmanaperumalsamy P. Fitoterapia 2002, 73:160.
3. Xiao L., Jiao N., He J., Sun W.J. Chin. J. Pharm. Anal. 2009, 29:876.
4. Suryawanshi S., Mehrotra N., Asthana R.K., Gupta R.C. Rapid. Commun. Mass Spectrom. 2006, 20:3761.
5. Kumarasamy Y., Nahar L., Cox P.J., Jaspars M., Sarker S.D. Phytomedicine 2003, 10:344.
6. Vaidya H., Rajani M., Sudarsanam V., Padh H., Goyal R. J. Nat. Med. 2009, 63:437.
7. Vaidya H., Rajani M., Sudarsanam V., Padh H., Goyal R. Eur. J. Pharmacol. 2009, 617:108.
8. Jaishree V., Badami S., RupeshKumar M., Tamizhmani T. Phytomedicine 2009, 16:227.
9. Vaijanathappa J., Badami S. Planta Med. 2009, 75:12.
10. Jaishree V., Badami S. J. Ethnopharmacol. 2010, 130:103.
11. Xu K., Shen J., Li F., Liu J., Liu G., Tan J., Tan G. Zhongguo Zhong Yao Za Zhi 2009, 34:1384.
12. Huang W.Z., Xu C.H., Zhou D.C., Tong L.H., Ye Z.G. Zhongguo Zhong Yao Za Zhi 2007, 32:2494.
13. Takei H., Nakauchi K., Yoshizaki F. Anal. Sci. 2001, 17:885.
14. Aberham A., Schwaiger S., Stuppner H., Ganzera M. J. Pharm. Biomed. Anal. 2007, 45:437.
15. Suryawanshi S., Asthana R.K., Gupta R.C. J. Chromatogr. B 2007, 858:211.
16. Guidance for Industry, Bioanalytical Method Validation, US Department of Health and Human Services Food and Drug Administration, Center for Drug Evaluation and Research (CDER), 2001 Center for Veterinary Medicine (CV), May 2001. http://www/fda.gov/cder/guidance/index.htm.