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Volumn 39, Issue 4, 2013, Pages 494-504

Novel cell-based assay reveals associations of circulating serum AhR-ligands with metabolic syndrome and mitochondrial dysfunction

Author keywords

Alternative test method development; Aryl hydrocarbon receptor; Dioxins; Insulin resistance; Metabolic syndrome; Mitochondrial dysfunction; Obesity; POPs

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ADENOSINE TRIPHOSPHATE; AROMATIC HYDROCARBON RECEPTOR; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; GLUCOSE BLOOD LEVEL; POLLUTANT; TRIACYLGLYCEROL;

EID: 84881662568     PISSN: 09516433     EISSN: 18728081     Source Type: Journal    
DOI: 10.1002/biof.1092     Document Type: Article
Times cited : (42)

References (39)
  • 1
    • 33745918689 scopus 로고    scopus 로고
    • Introduction: globalization and the non-communicable disease epidemic
    • Zimmet, P. Z. and Alberti, K. G. (2006) Introduction: globalization and the non-communicable disease epidemic. Obesity (Silver Spring) 14, 1-3.
    • (2006) Obesity (Silver Spring) , vol.14 , pp. 1-3
    • Zimmet, P.Z.1    Alberti, K.G.2
  • 2
    • 79960202841 scopus 로고    scopus 로고
    • Type 2 diabetes across generations: from pathophysiology to prevention and management
    • Nolan, C. J., Damm, P., and Prentki, M. (2011) Type 2 diabetes across generations: from pathophysiology to prevention and management. Lancet 378, 169-181.
    • (2011) Lancet , vol.378 , pp. 169-181
    • Nolan, C.J.1    Damm, P.2    Prentki, M.3
  • 3
    • 0035344913 scopus 로고    scopus 로고
    • Peripheral blood mitochondrial DNA content is related to insulin sensitivity in offspring of type 2 diabetic patients
    • Song, J., Oh, J. Y., Sung, Y. A., Pak, Y. K., Park, K. S., et al. (2001) Peripheral blood mitochondrial DNA content is related to insulin sensitivity in offspring of type 2 diabetic patients. Diab. Care 24, 865-869.
    • (2001) Diab. Care , vol.24 , pp. 865-869
    • Song, J.1    Oh, J.Y.2    Sung, Y.A.3    Pak, Y.K.4    Park, K.S.5
  • 4
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • Lowell, B. B. and Shulman, G. I. (2005) Mitochondrial dysfunction and type 2 diabetes. Science 307, 384-387.
    • (2005) Science , vol.307 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 5
    • 70449484092 scopus 로고    scopus 로고
    • The role of mitochondria in health and disease
    • Johannsen, D. L. and Ravussin, E. (2009) The role of mitochondria in health and disease. Curr. Opin. Pharmacol. 9, 780-786.
    • (2009) Curr. Opin. Pharmacol. , vol.9 , pp. 780-786
    • Johannsen, D.L.1    Ravussin, E.2
  • 6
    • 44449122886 scopus 로고    scopus 로고
    • Environmental pollution and diabetes: a neglected association
    • Jones, O. A., Maguire, M. L., and Griffin, J. L. (2008) Environmental pollution and diabetes: a neglected association. Lancet 371, 287-288.
    • (2008) Lancet , vol.371 , pp. 287-288
    • Jones, O.A.1    Maguire, M.L.2    Griffin, J.L.3
  • 7
    • 80052084488 scopus 로고    scopus 로고
    • The paradox of progress: environmental disruption of metabolism and the diabetes epidemic
    • Neel, B. A. and Sargis, R. M. (2011) The paradox of progress: environmental disruption of metabolism and the diabetes epidemic. Diabetes 60, 1838-1848.
    • (2011) Diabetes , vol.60 , pp. 1838-1848
    • Neel, B.A.1    Sargis, R.M.2
  • 8
    • 33746422641 scopus 로고    scopus 로고
    • A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999-2002
    • Lee, D. H., Lee, I. K., Song, K., Steffes, M., Toscano, W., et al. (2006) A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999-2002. Diab. Care 29, 1638-1644.
    • (2006) Diab. Care , vol.29 , pp. 1638-1644
    • Lee, D.H.1    Lee, I.K.2    Song, K.3    Steffes, M.4    Toscano, W.5
  • 9
    • 33847653870 scopus 로고    scopus 로고
    • Association between serum concentrations of persistent organic pollutants and insulin resistance among nondiabetic adults: results from the National Health and Nutrition Examination Survey 1999-2002
    • Lee, D. H., Lee, I. K., Jin, S. H., Steffes, M., and Jacobs, D. R. Jr. (2007) Association between serum concentrations of persistent organic pollutants and insulin resistance among nondiabetic adults: results from the National Health and Nutrition Examination Survey 1999-2002. Diab. Care 30, 622-628.
    • (2007) Diab. Care , vol.30 , pp. 622-628
    • Lee, D.H.1    Lee, I.K.2    Jin, S.H.3    Steffes, M.4    Jacobs, D.R.5
  • 10
    • 67349154088 scopus 로고    scopus 로고
    • Endocrine disrupters as obesogens
    • Grun, F. and Blumberg, B. (2009) Endocrine disrupters as obesogens. Mol. Cell Endocrinol. 304, 19-29.
    • (2009) Mol. Cell Endocrinol. , vol.304 , pp. 19-29
    • Grun, F.1    Blumberg, B.2
  • 11
    • 79953205215 scopus 로고    scopus 로고
    • Obesity and persistent organic pollutants: possible obesogenic effect of organochlorine pesticides and polychlorinated biphenyls
    • Dirinck, E., Jorens, P. G., Covaci, A., Geens, T., Roosens, L., et al. (2011) Obesity and persistent organic pollutants: possible obesogenic effect of organochlorine pesticides and polychlorinated biphenyls. Obesity (Silver Spring) 19, 709-714.
    • (2011) Obesity (Silver Spring) , vol.19 , pp. 709-714
    • Dirinck, E.1    Jorens, P.G.2    Covaci, A.3    Geens, T.4    Roosens, L.5
  • 12
    • 79551515105 scopus 로고    scopus 로고
    • Low dose organochlorine pesticides and polychlorinated biphenyls predict obesity, dyslipidemia, and insulin resistance among people free of diabetes
    • Lee, D. H., Steffes, M. W., Sjodin, A., Jones, R. S., Needham, L. L., et al. (2011) Low dose organochlorine pesticides and polychlorinated biphenyls predict obesity, dyslipidemia, and insulin resistance among people free of diabetes. PLoS One 6, e15977.
    • (2011) PLoS One , vol.6
    • Lee, D.H.1    Steffes, M.W.2    Sjodin, A.3    Jones, R.S.4    Needham, L.L.5
  • 13
    • 77957371033 scopus 로고    scopus 로고
    • Polychlorinated biphenyls (PCBs) contamination and aryl hydrocarbon receptor (AhR) agonist activity of Omega-3 polyunsaturated fatty acid supplements: implications for daily intake of dioxins and PCBs
    • Bourdon, J. A., Bazinet, T. M., Arnason, T. T., Kimpe, L. E., Blais, J. M., et al. (2010) Polychlorinated biphenyls (PCBs) contamination and aryl hydrocarbon receptor (AhR) agonist activity of Omega-3 polyunsaturated fatty acid supplements: implications for daily intake of dioxins and PCBs. Food Chem. Toxicol 48, 3093-3097.
    • (2010) Food Chem. Toxicol , vol.48 , pp. 3093-3097
    • Bourdon, J.A.1    Bazinet, T.M.2    Arnason, T.T.3    Kimpe, L.E.4    Blais, J.M.5
  • 14
    • 77649225956 scopus 로고    scopus 로고
    • Association of low-dose exposure to persistent organic pollutants with global DNA hypomethylation in healthy Koreans
    • Kim, K. Y., Kim, D. S., Lee, S. K., Lee, I. K., Kang, J. H., et al. (2010) Association of low-dose exposure to persistent organic pollutants with global DNA hypomethylation in healthy Koreans. Environ. Health Perspect. 118, 370-374.
    • (2010) Environ. Health Perspect. , vol.118 , pp. 370-374
    • Kim, K.Y.1    Kim, D.S.2    Lee, S.K.3    Lee, I.K.4    Kang, J.H.5
  • 15
    • 0036737088 scopus 로고    scopus 로고
    • Combining xenoestrogens at levels below individual no-observed-effect concentrations dramatically enhances steroid hormone action
    • Rajapakse, N., Silva, E., and Kortenkamp, A. (2002) Combining xenoestrogens at levels below individual no-observed-effect concentrations dramatically enhances steroid hormone action. Environ. Health Perspect. 110, 917-921.
    • (2002) Environ. Health Perspect. , vol.110 , pp. 917-921
    • Rajapakse, N.1    Silva, E.2    Kortenkamp, A.3
  • 16
    • 79953753361 scopus 로고    scopus 로고
    • Persistent organic pollutants and epidemic of diabetes and metabolic syndrome
    • Lee, H. K. (2010) Persistent organic pollutants and epidemic of diabetes and metabolic syndrome. J. Diab. Invest. 1, 121-122.
    • (2010) J. Diab. Invest. , vol.1 , pp. 121-122
    • Lee, H.K.1
  • 17
    • 0038768712 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
    • Denison, M. S. and Nagy, S. R. (2003) Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol. 43, 309-334.
    • (2003) Annu. Rev. Pharmacol. Toxicol. , vol.43 , pp. 309-334
    • Denison, M.S.1    Nagy, S.R.2
  • 18
    • 71449114195 scopus 로고    scopus 로고
    • An overview of the effects of dioxins and dioxin-like compounds on vertebrates, as documented in human and ecological epidemiology
    • White, S. S. and Birnbaum, L. S. (2009) An overview of the effects of dioxins and dioxin-like compounds on vertebrates, as documented in human and ecological epidemiology. J. Environ. Sci. Health C Environ. Carcinog. Ecotoxicol. Rev. 27, 197-211.
    • (2009) J. Environ. Sci. Health C Environ. Carcinog. Ecotoxicol. Rev. , vol.27 , pp. 197-211
    • White, S.S.1    Birnbaum, L.S.2
  • 19
    • 0034064338 scopus 로고    scopus 로고
    • Development and modification of a recombinant cell bioassay to directly detect halogenated and polycyclic aromatic hydrocarbons in serum
    • Ziccardi, M. H., Gardner, I. A., and Denison, M. S. (2000) Development and modification of a recombinant cell bioassay to directly detect halogenated and polycyclic aromatic hydrocarbons in serum. Toxicol. Sci. 54, 183-193.
    • (2000) Toxicol. Sci. , vol.54 , pp. 183-193
    • Ziccardi, M.H.1    Gardner, I.A.2    Denison, M.S.3
  • 20
    • 77951738343 scopus 로고    scopus 로고
    • Direct assessment of cumulative aryl hydrocarbon receptor agonist activity in sera from experimentally exposed mice and environmentally exposed humans
    • Schlezinger, J. J., Bernard, P. L., Haas, A., Grandjean, P., Weihe, P., et al (2010) Direct assessment of cumulative aryl hydrocarbon receptor agonist activity in sera from experimentally exposed mice and environmentally exposed humans. Environ Health Perspect. 118, 693-698.
    • (2010) Environ Health Perspect. , vol.118 , pp. 693-698
    • Schlezinger, J.J.1    Bernard, P.L.2    Haas, A.3    Grandjean, P.4    Weihe, P.5
  • 21
    • 77952886949 scopus 로고    scopus 로고
    • Determinants of AhR-mediated transcriptional activity induced by plasma extracts from Nunavik Inuit adults
    • Medehouenou, T. C., Larochelle, C., Dumas, P., Dewailly, E., and Ayotte, P. (2010) Determinants of AhR-mediated transcriptional activity induced by plasma extracts from Nunavik Inuit adults. Chemosphere 80, 75-82.
    • (2010) Chemosphere , vol.80 , pp. 75-82
    • Medehouenou, T.C.1    Larochelle, C.2    Dumas, P.3    Dewailly, E.4    Ayotte, P.5
  • 22
    • 2342489432 scopus 로고    scopus 로고
    • Comparison of recombinant cell bioassays for the detection of Ah receptor agonists
    • Han, D., Nagy, S. R., and Denison, M. S. (2004) Comparison of recombinant cell bioassays for the detection of Ah receptor agonists. Biofactors 20, 11-22.
    • (2004) Biofactors , vol.20 , pp. 11-22
    • Han, D.1    Nagy, S.R.2    Denison, M.S.3
  • 23
    • 61649109754 scopus 로고    scopus 로고
    • Dioxin and dioxin-like PCB profiles in the serum of industrial and municipal waste incinerator workers in Korea
    • Park, H., Ikonomou, M. G., Kim, H. S., Choi, J. W., and Chang, Y. S. (2009) Dioxin and dioxin-like PCB profiles in the serum of industrial and municipal waste incinerator workers in Korea. Environ. Int. 35, 580-587.
    • (2009) Environ. Int. , vol.35 , pp. 580-587
    • Park, H.1    Ikonomou, M.G.2    Kim, H.S.3    Choi, J.W.4    Chang, Y.S.5
  • 24
    • 77950300655 scopus 로고    scopus 로고
    • Relative importance of polychlorinated naphthalenes compared to dioxins, and polychlorinated biphenyls in human serum from Korea: contribution to TEQs and potential sources
    • Park, H., Kang, J. H., Baek, S. Y., and Chang, Y. S. (2010) Relative importance of polychlorinated naphthalenes compared to dioxins, and polychlorinated biphenyls in human serum from Korea: contribution to TEQs and potential sources. Environ. Pollut. 158, 1420-1427.
    • (2010) Environ. Pollut. , vol.158 , pp. 1420-1427
    • Park, H.1    Kang, J.H.2    Baek, S.Y.3    Chang, Y.S.4
  • 25
    • 84859422737 scopus 로고    scopus 로고
    • Overexpression of TFAM, NRF-1 and myr-AKT protects the MPP(+)-induced mitochondrial dysfunctions in neuronal cells
    • Piao, Y., Kim, H. G., Oh, M. S., and Pak, Y. K. (2012) Overexpression of TFAM, NRF-1 and myr-AKT protects the MPP(+)-induced mitochondrial dysfunctions in neuronal cells. Biochim. Biophys. Acta 1820, 577-585.
    • (2012) Biochim. Biophys. Acta , vol.1820 , pp. 577-585
    • Piao, Y.1    Kim, H.G.2    Oh, M.S.3    Pak, Y.K.4
  • 26
    • 79954526957 scopus 로고    scopus 로고
    • Shot-gun proteomic analysis of mitochondrial D-loop DNA binding proteins: identification of mitochondrial histones
    • Choi, Y. S., Jeong, J. H., Min, H. K., Jung, H. J., Hwang, D., et al. (2011) Shot-gun proteomic analysis of mitochondrial D-loop DNA binding proteins: identification of mitochondrial histones. Mol Biosyst 7, 1523-1536.
    • (2011) Mol Biosyst , vol.7 , pp. 1523-1536
    • Choi, Y.S.1    Jeong, J.H.2    Min, H.K.3    Jung, H.J.4    Hwang, D.5
  • 27
    • 79551521189 scopus 로고    scopus 로고
    • A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells
    • Birket, M. J., Orr, A. L., Gerencser, A. A., Madden, D. T., Vitelli, C., et al. (2011) A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells. J Cell Sci 124, 348-358.
    • (2011) J Cell Sci , vol.124 , pp. 348-358
    • Birket, M.J.1    Orr, A.L.2    Gerencser, A.A.3    Madden, D.T.4    Vitelli, C.5
  • 28
    • 77954071572 scopus 로고    scopus 로고
    • Endocrine disruptor, dioxin (TCDD)-induced mitochondrial dysfunction and apoptosis in human trophoblast-like JAR cells
    • Chen, S. C., Liao, T. L., Wei, Y. H., Tzeng, C. R., and Kao, S. H., (2010) Endocrine disruptor, dioxin (TCDD)-induced mitochondrial dysfunction and apoptosis in human trophoblast-like JAR cells. Mol. Hum. Reprod. 16, 361-372.
    • (2010) Mol. Hum. Reprod. , vol.16 , pp. 361-372
    • Chen, S.C.1    Liao, T.L.2    Wei, Y.H.3    Tzeng, C.R.4    Kao, S.H.5
  • 29
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • Kelley, D. E., He, J., Menshikova, E. V., and Ritov, V. B. (2002) Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 51, 2944-2950.
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 30
    • 57749100271 scopus 로고    scopus 로고
    • Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells
    • Park, K. S., Wiederkehr, A., Kirkpatrick, C., Mattenberger, Y., Martinou, J. C., et al. (2008) Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells. J. Biol. Chem. 283, 33347-33356.
    • (2008) J. Biol. Chem. , vol.283 , pp. 33347-33356
    • Park, K.S.1    Wiederkehr, A.2    Kirkpatrick, C.3    Mattenberger, Y.4    Martinou, J.C.5
  • 31
    • 76749110211 scopus 로고    scopus 로고
    • Mitochondrial dysfunction enhances the migration of vascular smooth muscles cells via suppression of Akt phosphorylation
    • Ahn, S. Y., Choi, Y. S., Koo, H. J., Jeong, J. H., Park, W. H., et al. (2010) Mitochondrial dysfunction enhances the migration of vascular smooth muscles cells via suppression of Akt phosphorylation. Biochim. Biophys. Acta 1800, 275-281.
    • (2010) Biochim. Biophys. Acta , vol.1800 , pp. 275-281
    • Ahn, S.Y.1    Choi, Y.S.2    Koo, H.J.3    Jeong, J.H.4    Park, W.H.5
  • 32
    • 77951668711 scopus 로고    scopus 로고
    • Persistent organic pollutant exposure leads to insulin resistance syndrome
    • Ruzzin, J., Petersen, R., Meugnier, E., Madsen, L., Lock, E. J., et al (2010) Persistent organic pollutant exposure leads to insulin resistance syndrome. Environ Health Perspect 118, 465-471.
    • (2010) Environ Health Perspect , vol.118 , pp. 465-471
    • Ruzzin, J.1    Petersen, R.2    Meugnier, E.3    Madsen, L.4    Lock, E.J.5
  • 33
    • 23044434517 scopus 로고    scopus 로고
    • Association between cigarette smoking and metabolic syndrome: the Korea National Health and Nutrition Examination Survey
    • Oh, S. W., Yoon, Y. S., Lee, E. S., Kim, W. K., Park, C., et al. (2005) Association between cigarette smoking and metabolic syndrome: the Korea National Health and Nutrition Examination Survey. Diab. Care 28, 2064-2066.
    • (2005) Diab. Care , vol.28 , pp. 2064-2066
    • Oh, S.W.1    Yoon, Y.S.2    Lee, E.S.3    Kim, W.K.4    Park, C.5
  • 34
    • 84862833090 scopus 로고    scopus 로고
    • Polychlorinated biphenyls and organochlorine pesticides in plasma predict development of type 2 diabetes in the elderly: the prospective investigation of the vasculature in Uppsala Seniors (PIVUS) study
    • Lee, D. H., Lind, P. M., Jacobs, D. R. Jr., Salihovic, S., van Bavel, B., et al. (2011) Polychlorinated biphenyls and organochlorine pesticides in plasma predict development of type 2 diabetes in the elderly: the prospective investigation of the vasculature in Uppsala Seniors (PIVUS) study. Diab. Care 34, 1778-1784.
    • (2011) Diab. Care , vol.34 , pp. 1778-1784
    • Lee, D.H.1    Lind, P.M.2    Jacobs, D.R.3    Salihovic, S.4    van Bavel, B.5
  • 35
    • 84863122866 scopus 로고    scopus 로고
    • Chronic alcohol exposure stimulates adipose tissue lipolysis in mice: role of reverse triglyceride transport in the pathogenesis of alcoholic steatosis
    • Zhong, W., Zhao, Y., Tang, Y., Wei, X., Shi, X., et al. (2012) Chronic alcohol exposure stimulates adipose tissue lipolysis in mice: role of reverse triglyceride transport in the pathogenesis of alcoholic steatosis. Am. J. Pathol. 180, 998-1007.
    • (2012) Am. J. Pathol. , vol.180 , pp. 998-1007
    • Zhong, W.1    Zhao, Y.2    Tang, Y.3    Wei, X.4    Shi, X.5
  • 36
    • 80052538342 scopus 로고    scopus 로고
    • Environmental pollutants and type 2 diabetes: a review of mechanisms that can disrupt beta cell function
    • van der
    • Hectors, T. L., Vanparys, C., van derVen, K., Martens, G. A., Jorens, P. G., et al. (2011) Environmental pollutants and type 2 diabetes: a review of mechanisms that can disrupt beta cell function. Diabetologia 54, 1273-1290.
    • (2011) Diabetologia , vol.54 , pp. 1273-1290
    • Hectors, T.L.1    Vanparys, C.2    Ven, K.3    Martens, G.A.4    Jorens, P.G.5
  • 37
    • 84866384189 scopus 로고    scopus 로고
    • The association between obesity and mortality in the elderly differs by serum concentrations of persistent organic pollutants: a possible explanation for the obesity paradox
    • Hong, N. S., Kim, K. S., Lee, I. K., Lind, P. M., Lind, L., et al. (2012) The association between obesity and mortality in the elderly differs by serum concentrations of persistent organic pollutants: a possible explanation for the obesity paradox. Int. J. Obes. (Lond) 36, 1170-1175.
    • (2012) Int. J. Obes. (Lond) , vol.36 , pp. 1170-1175
    • Hong, N.S.1    Kim, K.S.2    Lee, I.K.3    Lind, P.M.4    Lind, L.5
  • 38
    • 84856220489 scopus 로고    scopus 로고
    • Associations of persistent organic pollutants with abdominal obesity in the elderly: the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study
    • Lee, D. H., Lind, L., Jacobs, D. R., Jr., Salihovic, S., B. van Bavel, et al. (2012) Associations of persistent organic pollutants with abdominal obesity in the elderly: the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Environ. Int. 40, 170-178.
    • (2012) Environ. Int. , vol.40 , pp. 170-178
    • Lee, D.H.1    Lind, L.2    Jacobs, D.R.3    Salihovic, S.4    van Bavel, B.5
  • 39
    • 80054041992 scopus 로고    scopus 로고
    • An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
    • Opitz, C. A., Litzenburger, U. M., Sahm, F., Ott, M., Tritschler, I., et al. (2011) An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature 478, 197-203.
    • (2011) Nature , vol.478 , pp. 197-203
    • Opitz, C.A.1    Litzenburger, U.M.2    Sahm, F.3    Ott, M.4    Tritschler, I.5


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