Preconditioning with soluble guanylate cyclase activation prevents postischemic inflammation and reduces nitrate tolerance in heme oxygenase-1 knockout mice

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 305, Issue 4, 2013, Pages

  Wang, Walter Z ^a   Jones, Allan W ^a,b   Wang, Meifang ^a   Durante, William ^a   Korthuis, Ronald J ^a,b  

^a University of Missouri   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

BAY 41 2272; BAY 60 2770; Endothelial nitric oxide synthase; Ischemia reperfusion; Leukocyte rolling and adhesion; Protein kinase G; Vascular smooth muscle

Indexed keywords

4 AMINO 5 CYCLOPROPYL 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL]PYRIMIDINE; ACETYLCHOLINE; BAY 60 2270; CARDIOVASCULAR AGENT; CYCLIC GMP DEPENDENT PROTEIN KINASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GUANYLATE CYCLASE; HEME OXYGENASE 1; NITRATE; NITROPRUSSIDE SODIUM; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; FLUORESCENCE MICROSCOPY; HEART PROTECTION; ISCHEMIC PRECONDITIONING; KNOCKOUT MOUSE; LEUKOCYTE ADHERENCE; LEUKOCYTE ROLLING; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; SMALL INTESTINE; SUPERIOR MESENTERIC ARTERY; WESTERN BLOTTING;

BAY 41-2272; BAY 60-2770; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ISCHEMIA-REPERFUSION; LEUKOCYTE ROLLING AND ADHESION; PROTEIN KINASE G; VASCULAR SMOOTH MUSCLE;

ANIMALS; BENZOATES; BIPHENYL COMPOUNDS; CYCLIC GMP-DEPENDENT PROTEIN KINASES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME ACTIVATORS; GUANYLATE CYCLASE; HEME OXYGENASE-1; HYDROCARBONS, FLUORINATED; HYDROGEN SULFIDE; INFLAMMATION; INFLAMMATION MEDIATORS; INTESTINE, SMALL; ISCHEMIA; LEUKOCYTE ROLLING; MEMBRANE PROTEINS; MESENTERIC ARTERY, SUPERIOR; MESENTERIC VASCULAR OCCLUSION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PYRAZOLES; PYRIDINES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR DISEASES; VASODILATION; VENULES;

EID: 84881657340     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00810.2012     Document Type: Article

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