Isolation, characterization, and hepatoprotective effects of the raffinose family oligosaccharides from rehmannia glutinosa libosch

Journal of Agricultural and Food Chemistry

Volumn 61, Issue 32, 2013, Pages 7786-7793

  Zhang, Ruijun ^a   Zhao, Yan ^b   Sun, Yanfei ^a   Lu, Xinshan ^a   Yang, Xingbin ^a  

^a SHAANXI NORMAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

carbon tetrachloride; hepatoprotective effect; HPLC; raffinose family oligosaccharides; Rehmannia glutinosa Libosch

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; GLUTATHIONE PEROXIDASE; HEPATOPROTECTIVE EFFECTS; HPLC; RAFFINOSE FAMILY OLIGOSACCHARIDES; REHMANNIA GLUTINOSA; TOTAL ANTIOXIDANT CAPACITY;

AMINO ACIDS; CARBON TETRACHLORIDE; MAMMALS; OXYGEN; PEPTIDES;

PLANTS (BOTANY);

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; PLANT EXTRACT; PROTECTIVE AGENT; RAFFINOSE;

ANIMAL; ARTICLE; BLOOD; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; HUMAN; ISOLATION AND PURIFICATION; LIVER; MALE; METABOLISM; MOUSE; OXIDATIVE STRESS; REHMANNIA; TOXIC HEPATITIS;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CARBON TETRACHLORIDE; DRUG-INDUCED LIVER INJURY; GLUTATHIONE PEROXIDASE; HUMANS; LIVER; MALE; MALONDIALDEHYDE; MICE; OXIDATIVE STRESS; PLANT EXTRACTS; PROTECTIVE AGENTS; RAFFINOSE; REHMANNIA;

EID: 84881645100     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf4018492     Document Type: Article

References (33)

1. Backhed, F.; Ley, R. E.; Sonnenburg, J. L.; Peterson, D. A.; Gordon, J. I. Host-bacterial mutualism in the human intestine Science 2005, 307, 1915-1920
2. Servin, A. L. Antagonistic activities of lactobacilli and bifidobacteria against microbial pathogens FEMS Microbiol. Rev. 2004, 28, 405-440
3. Yang, X. B.; Zhao, Y.; He, N. W.; Crof, K. D. Isolation, characterization, and immunological effects of α-galacto-oligosaccharides from a new source, the herb Lycopus lucidus turcz J. Agric. Food Chem. 2010, 58, 8253-8258
4. Liebregts, T.; Adam, B.; Bredack, C.; Röth, A.; Heinzel, S.; Lester, S.; Downie, D. S.; Smith, E.; Drew, P.; Talley, N. J.; Holtman, G. Immune activation in patients with irritable bowel syndrome Gastroenterology 2007, 132, 913-920
5. Mussatto, S. I.; Mancilha, I. M. Non-digestible oligosaccharides: a review Carbohydr. Polym. 2007, 68, 587-597
6. Crittenden, R. G.; Playne, M. J. Production, properties and applications of food-grade oligosaccharides Trends Food Sci. Technol. 1996, 7, 353-361
7. Xu, Q.; Chao, Y. L.; Wan, Q. B. Health benefit application of functional oligosaccharides Carbohydr. Polym. 2009, 77, 435-441
8. Rastall, R. A. Functional oligosaccharides: Application and manufacture Annu. Rev. Food Sci. Technol. 2010, 1, 305-339
9. Yao, H. T.; Luo, M. N.; Hung, L. B.; Chiang, M. T.; Lin, J. H.; Lii, C. K.; Huang, C. Y. Effects of chitosan oligosaccharides on drug-metabolizing enzymes in rat liver and kidneys Food Chem. Toxicol. 2012, 50, 1171-1177
10. Chen, H. M.; Yan, X. J. Antioxidant activities of agaro-oligosaccharides with different degrees of polymerization in cell-based system Biochim. Biophys. Acta 2005, 1722, 103-111
11. Chen, H.; Yan, X. J.; Zhu, P.; Lin, J. Antioxidant activity and hepatoprotective potential of agaro-oligosaccharides in vitro and in vivo Nutr. J. 2006, 5, 31-43
12. Zhang, R. X.; Li, M. X.; Jia, Z. P. Rehmannia glutinosa: Review of botany, chemistry and pharmacology J. Ethnopharmacol. 2008, 117, 199-214
13. Zhang, R. X.; Zhou, J. H.; Jia, Z. P.; Zhang, Y. X.; Gu, G. M. Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism J. Ethnopharmacol. 2004, 90, 39-43
14. Wu, P. S.; Wu, S. J.; Tsai, Y. H.; Lin, Y. H.; Chao, J. C. Hot water extracted Lycium barbarumand and Rehmannia glutinosa inhibit liver inflammation and fibrosis in rats Am. J. Chin. Med. 2011, 39, 1173-1191
15. Liu, Y. F.; Liang, D.; Luo, H.; Hao, Z. Y.; Wang, Y.; Zhang, C. L.; Zhang, Q. J.; Chen, R. Y.; Yu, D. Q. Hepatoprotective iridoid glycosides from the roots of Rehmannia glutinosa J. Nat. Prod. 2012, 75, 1625-1631
16. Zhang, Y.; Wang, Y. H.; Wang, L.; Zhang, Y. Q.; Qin, Y. H.; Chen, T.; Hang, W. D.; Cheng, G. H. Effects of Rehmannia glutinosa oligosaccharide on human adipose-derived mesenchymal stem cells in vitro Life Sci. 2012, 91, 1323-1327
17. Halliwell, B.; Gutteridge, J. M. C.; Cross, C. E. Free-radicals, antioxidants, and human disease: where are we now? J. Lab. Clin. Med. 1992, 119, 598-620
18. Wang, D. Y.; Zhao, Y.; Jiao, Y. D.; Yu, L. H.; Yang, S.; Yang, X. B. Antioxidative and hepatoprotective effects of the polysaccharides from Zizyphus jujube cv. Shaanbeitanzao Carbohydr. Polym. 2012, 88, 1453-1459
19. Xiang, X. L.; Yang, L. Y.; Hua, S.; Li, W.; Sun, Y.; Ma, H.; Zhang, J. S.; Zeng, X. X. Determination of oligosaccharide contents in 19 cultivars of chickpea (Cicer arietinum L) seeds by high performance liquid chromatography Food Chem. 2008, 111, 215-219
20. 4-induced acute liver damage in mice J. Agric. Food Chem. 2010, 58, 6525-6531
21. Beena, R. K.; Krishna, S. K.; Pattabiraman, T. N. A short-duration colorimetric method based on phenol-sulfuric acid reaction for the estimation of glucoseylhemoglobin Biochem. Med. 1984, 31, 65-72
22. Tian, L. M.; Shi, X. L.; Yu, L. H.; Zhu, J.; Ma, R.; Yang, X. B. Chemical composition and hepatoprotective effects of polyphenol-rich extract from Houttuynia cordata tea J. Agric. Food Chem. 2012, 60, 4641-4648
23. Martianez-villaluenga, C.; Frias, J.; Gulewicz, K.; Vidal-valverde, C. Improved method to obtain pure α-galactosides from lupin seeds J. Agric. Food Chem. 2004, 52, 6920-6922
24. Vulevic, J.; Drakoularakou, A.; Yaqoob, P.; Tzortzis, G.; Gibson, G. R. Modulation of the fecal microflora profile and immune function by a novel trans -galactooligosaccharide mixture (B-GOS) in healthy elderly volunteers Am. J. Clin. Nutr. 2008, 88, 1438-1446
25. Chau, C. F.; Wu, S. H. The development of regulations of Chinese herbal medicines for both medicinal and food uses Trends. Food Sci. Technol. 2006, 17, 313-323
26. Tosh, S. M.; Yada, S. Dietary fibres in pulse seeds and fractions: Characterization, functional attributes, and applications Food Res. Int. 2010, 43, 450-460
27. Fernandez-Checa, J. C.; Kaplowitz, N. Hepatic mitochondrial glutathione: transport and role in disease and toxicity Toxicol. Appl. Pharmacol. 2005, 204, 263-273
28. Johnston, D. E.; Kroening, C. Mechanism of early carbon tetrachloride toxicity in cultured rat hepatocytes Pharmacol. Toxicol. 1998, 83, 231-239
29. Hamza, R. G.; El-Shennawy, H. M. Role of vitamin E and/or high protein diet in modulating antioxidant status and certain biochemical changes in gamma-irradiated rats J. Rad. Res. Appl. Sci. 2009, 2, 31-48
30. 4-induced acute liver damage in mice Food Chem. Toxicol. 2013, 55, 234-240
31. Mihailovic, V.; Mihailovic, M.; Uskokovic, A.; Arambašic, J.; Mišic, D.; Stankovic, V.; Katanic, J.; Mladenovic, M.; Solujic, S.; Matic, S. Hepatoprotective effects of Gentiana asclepiadea L. extracts against carbon tetrachloride induced liver injury in rats Food Chem. Toxicol. 2013, 52, 83-90
32. Fang, Y. Z.; Yang, S.; Wu, G. Y. Free radicals, antioxidants, and nutrition Nutrition 2002, 18, 872-879
33. Kankofer, M.; Lipko, J.; Zdunczyk, S. Total antioxidant capacity of bovine spontaneously released and retained placenta Pathophysiology 2005, 11, 215-219