메뉴 건너뛰기




Volumn 39, Issue 6, 2011, Pages 1173-1191

Hot water extracted Lycium barbarum and Rehmannia glutinosa inhibit liver inflammation and fibrosis in rats

Author keywords

Cytokines; Herbal Extract; Hydroxyproline; Liver Injury; Polysaccharides; Transforming Growth Factor 1

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; HOT WATER; HYDROXYPROLINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; LYCIUM BARBARUM EXTRACT; OLIVE OIL; REHMANNIA GLUTINOSA EXTRACT; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

EID: 81155153692     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X11009482     Document Type: Article
Times cited : (41)

References (59)
  • 1
    • 58649100911 scopus 로고    scopus 로고
    • Lycium barbarum (goji) juice improves in vivo antioxidant biomarkers in serum of healthy adults
    • Amagase, H., B. Sun and C. Borek. Lycium barbarum (goji) juice improves in vivo antioxidant biomarkers in serum of healthy adults. Nutr. Res. 29: 19-25, 2009.
    • (2009) Nutr. Res. , vol.29 , pp. 19-25
    • Amagase, H.1    Sun, B.2    Borek, C.3
  • 2
    • 0004202155 scopus 로고
    • Association of Official Analytical Chemists 16th edn. AOAC International, Gaithersburg
    • Association of Official Analytical Chemists. In: Official Methods of Analysis of AOAC International, 16th edn. AOAC International, Gaithersburg, 1995.
    • (1995) Official Methods of Analysis of AOAC International
  • 5
    • 76449096111 scopus 로고    scopus 로고
    • Hepatoprotective effect of shidagonglao on acute liver injury induced by carbon tetrachloride
    • Chao, J., M.S. Lee, S. Amagaya, J.W. Liao, J.B. Wu, L.K. Ho and W.H. Peng. Hepatoprotective effect of shidagonglao on acute liver injury induced by carbon tetrachloride. Am. J. Chin. Med. 37: 1085-1097, 2009.
    • (2009) Am. J. Chin. Med. , vol.37 , pp. 1085-1097
    • Chao, J.1    Lee, M.S.2    Amagaya, S.3    Liao, J.W.4    Wu, J.B.5    Ho, L.K.6    Peng, W.H.7
  • 6
    • 33747516825 scopus 로고    scopus 로고
    • Hot water-extracted Lycium barbarum and Rehmannia glutinosa inhibit proliferation and induce apoptosis of hepatocellular carcinoma cells
    • Chao, J.C., S.W. Chiang, C.C. Wang, Y.H. Tsai and M.S. Wu. Hot water-extracted Lycium barbarum and Rehmannia glutinosa inhibit proliferation and induce apoptosis of hepatocellular carcinoma cells. World J. Gastroenterol. 12: 4478-4484, 2006.
    • (2006) World J. Gastroenterol. , vol.12 , pp. 4478-4484
    • Chao, J.C.1    Chiang, S.W.2    Wang, C.C.3    Tsai, Y.H.4    Wu, M.S.5
  • 7
    • 0027221660 scopus 로고
    • Immuno-tumoricidal effect of Rehmannia glutinosa polysaccharides b and its mechanism
    • Chen, M.S., X.W. Feng, J.H. Zhou and J.F. Tand. Immuno-tumoricidal effect of Rehmannia glutinosa polysaccharides b and its mechanism. Chin. J. Oncol. 7: 153-156, 1993.
    • (1993) Chin. J. Oncol. , vol.7 , pp. 153-156
    • Chen, M.S.1    Feng, X.W.2    Zhou, J.H.3    Tand, J.F.4
  • 8
    • 0029003179 scopus 로고
    • Effects of Rehmannia glutinosa polysaccharide b on T-lymphocytes in mice bearing sarcoma 180
    • Chen, L.Z., X.W. Feng and J.H. Zhou. Effects of Rehmannia glutinosa polysaccharide b on T-lymphocytes in mice bearing sarcoma 180. Zhongguo Yao Li Xue Bao 16: 337-340, 1995.
    • (1995) Zhongguo Yao Li Xue Bao , vol.16 , pp. 337-340
    • Chen, L.Z.1    Feng, X.W.2    Zhou, J.H.3
  • 9
    • 65449134760 scopus 로고    scopus 로고
    • Polysaccharide-protein complex from Lycium barbarum L. is a novel stimulus of dendritic cell immunogenicity
    • Chen, Z., J. Lu, N. Srinivasan, B.K. Tan and S.H. Chan. Polysaccharide-protein complex from Lycium barbarum L. is a novel stimulus of dendritic cell immunogenicity. J. Immunol. 182: 3503-3509, 2009a.
    • (2009) J. Immunol. , vol.182 , pp. 3503-3509
    • Chen, Z.1    Lu, J.2    Srinivasan, N.3    Tan, B.K.4    Chan, S.H.5
  • 10
    • 68049114319 scopus 로고    scopus 로고
    • Activation of macrophages by polysaccharide-protein complex from Lycium barbarum L
    • Chen, Z., M.Y. Soo, N. Srinivasan, B.K. Tan and S.H. Chan. Activation of macrophages by polysaccharide-protein complex from Lycium barbarum L. Phytother. Res. 23: 1116-1122, 2009b.
    • (2009) Phytother. Res. , vol.23 , pp. 1116-1122
    • Chen, Z.1    Soo, M.Y.2    Srinivasan, N.3    Tan, B.K.4    Chan, S.H.5
  • 12
    • 15444369928 scopus 로고    scopus 로고
    • Implications of oxidative stress and hepatic cytokine (TNF-a and IL-6) response in the pathogenesis of hepatic collagenesis in chronic arsenic toxicity
    • Das, S., A. Santra, S. Lahiri and D.N. Guha Mazumder. Implications of oxidative stress and hepatic cytokine (TNF-a and IL-6) response in the pathogenesis of hepatic collagenesis in chronic arsenic toxicity. Toxicol. Appl. Pharmacol. 204: 18-26, 2005.
    • (2005) Toxicol. Appl. Pharmacol. , vol.204 , pp. 18-26
    • Das, S.1    Santra, A.2    Lahiri, S.3    Guha Mazumder, D.N.4
  • 14
    • 0025127633 scopus 로고
    • Determination of aldehydic lipid peroxidation products: Mal- onaldehyde and 4-hydroxynonenal
    • Esterbauer, H. and K.H. Cheeseman. Determination of aldehydic lipid peroxidation products: mal- onaldehyde and 4-hydroxynonenal. Methods Enzymol. 186: 407-421, 1990.
    • (1990) Methods Enzymol. , vol.186 , pp. 407-421
    • Esterbauer, H.1    Cheeseman, K.H.2
  • 15
    • 0034723290 scopus 로고    scopus 로고
    • Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
    • Friedman, SL. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J. Biol. Chem. 275: 2247-2250, 2000.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2247-2250
    • Friedman, S.L.1
  • 16
    • 13844291152 scopus 로고    scopus 로고
    • Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum
    • Gan, L., S.H. Zhang, XL. Yang and H.B. Xu. Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum. Int. Immunopharmacol. 4: 563-569, 2004.
    • (2004) Int. Immunopharmacol. , vol.4 , pp. 563-569
    • Gan, L.1    Zhang, S.H.2    Yang, X.L.3    Xu, H.B.4
  • 17
    • 79956226372 scopus 로고    scopus 로고
    • Government Information Office. Public Health
    • Government Information Office. Public Health. In: The Republic of China Yearbook 2009.
    • (2009) The Republic of China Yearbook
  • 18
    • 81155146784 scopus 로고    scopus 로고
    • Government Information Office, Taipei, 2009
    • Government Information Office, Taipei, 2009.
  • 19
    • 77954594570 scopus 로고    scopus 로고
    • A study on the preventive effect of Lycium barbarum polysaccharide on the development of alcoholic fatty liver in rats and its possible mechanisms
    • Gu, S., PL. Wang and R. Jiang. A study on the preventive effect of Lycium barbarum polysaccharide on the development of alcoholic fatty liver in rats and its possible mechanisms. Zhonghua Gan Zang Bing Za Zhi 15: 204-208, 2007.
    • (2007) Zhonghua Gan Zang Bing Za Zhi , vol.15 , pp. 204-208
    • Gu, S.1    Wang, P.L.2    Jiang, R.3
  • 20
    • 0037485382 scopus 로고
    • The research of Lycium barbarum and Lycium barbarum polysaccharides ( I)
    • He, J. and S.H. Zhang. The research of Lycium barbarum and Lycium barbarum polysaccharides (I). Food Sci. 16: 14-21, 1995.
    • (1995) Food Sci. , vol.16 , pp. 14-21
    • He, J.1    Zhang, S.H.2
  • 21
    • 0036083181 scopus 로고    scopus 로고
    • TGF-ß isoform release and activation during in vitro bronchial epithelial wound repair
    • Howat, W.J., S.T. Holgate and P.M. Lackie. TGF-ß isoform release and activation during in vitro bronchial epithelial wound repair. Am. J. Physiol. Lung. Cell Mol. Physiol. 282: L115-123, 2002.
    • (2002) Am. J. Physiol. Lung. Cell Mol. Physiol. , vol.282
    • Howat, W.J.1    Holgate, S.T.2    Lackie, P.M.3
  • 22
    • 1842868414 scopus 로고    scopus 로고
    • The protective effects of total flavonoids from Lycium barbarum L. on lipid peroxidation of liver mitochondria and red blood cell in rats
    • Huang, Y., J. Lu, Y. Shen and J. Lu. The protective effects of total flavonoids from Lycium barbarum L. on lipid peroxidation of liver mitochondria and red blood cell in rats. Wei Sheng Yan Jiu 28: 115-116, 1999a.
    • (1999) Wei Sheng Yan Jiu , vol.28 , pp. 115-116
    • Huang, Y.1    Lu, J.2    Shen, Y.3    Lu, J.4
  • 23
    • 0033304389 scopus 로고    scopus 로고
    • Structure elucidation of glycan of glycoconjugate LbGp3 isolated from the fruit of Lycium barbarum L
    • Huang, L.J., G.Y. Tian and G.Z. Ji. Structure elucidation of glycan of glycoconjugate LbGp3 isolated from the fruit of Lycium barbarum L. J. Asian Nat. Prod. Res. 1: 259-267, 1999b.
    • (1999) J. Asian Nat. Prod. Res. , vol.1 , pp. 259-267
    • Huang, L.J.1    Tian, G.Y.2    Ji, G.Z.3
  • 27
    • 0032767110 scopus 로고    scopus 로고
    • Rehmannia glutinosa inhibits tumour necrosis factor-alpha and interleukin-1 secretion from mouse astrocytes
    • Kim, H.M., C.S. An, K.Y. Jung, Y.K. Choo, J.K. Park and S.Y. Nam. Rehmannia glutinosa inhibits tumour necrosis factor-alpha and interleukin-1 secretion from mouse astrocytes. Pharmacol. Res. 40: 171-176, 1999a.
    • (1999) Pharmacol. Res. , vol.40 , pp. 171-176
    • Kim, H.M.1    An, C.S.2    Jung, K.Y.3    Choo, Y.K.4    Park, J.K.5    Nam, S.Y.6
  • 28
    • 0032859450 scopus 로고    scopus 로고
    • A novel cerebroside from Lycii fructus preserves the hepatic glutathione redox system in primary cultures of rat hepatocytes
    • Kim, S.Y., E.J. Lee, H.P. Kim, Y.C. Kim, A. Moon and Y.C. Kim. A novel cerebroside from Lycii fructus preserves the hepatic glutathione redox system in primary cultures of rat hepatocytes. Biol. Pharm. Bull. 22: 873-875, 1999b.
    • (1999) Biol. Pharm. Bull. , vol.22 , pp. 873-875
    • Kim, S.Y.1    Lee, E.J.2    Kim, H.P.3    Kim, Y.C.4    Moon, A.5    Kim, Y.C.6
  • 29
    • 0033812532 scopus 로고    scopus 로고
    • LCC, a cerebroside from Lycium chinense, protects primary cultured rat hepatocytes exposed to galactosamine
    • Kim, S.Y., E.J. Lee, H.P. Kim, H.S. Lee and Y.C. Kim. LCC, a cerebroside from Lycium chinense, protects primary cultured rat hepatocytes exposed to galactosamine. Phytother. Res. 14: 448-451, 2000.
    • (2000) Phytother. Res. , vol.14 , pp. 448-451
    • Kim, S.Y.1    Lee, E.J.2    Kim, H.P.3    Lee, H.S.4    Kim, Y.C.5
  • 30
    • 59849113986 scopus 로고    scopus 로고
    • Rehmannia glutinosa ameliorates the progressive renal failure induced by 5/6 nephrectomy
    • Lee, B.C., J.B. Choi, H.J. Cho and Y.S. Kim. Rehmannia glutinosa ameliorates the progressive renal failure induced by 5/6 nephrectomy. J. Ethnopharmacol. 122: 131-135, 2009.
    • (2009) J. Ethnopharmacol. , vol.122 , pp. 131-135
    • Lee, B.C.1    Choi, J.B.2    Cho, H.J.3    Kim, Y.S.4
  • 31
    • 0030756676 scopus 로고    scopus 로고
    • The lipid peroxidation end product 4-hydroxy-2,3-nonenal up-regulates transforming growth factor beta1 expression in the macrophage lineage: A link between oxidative injury and fibrosclerosis
    • Leonarduzzi, G., A. Scavazza, F. Biasi, E. Chiarpotto, S. Camandola, S. Vogel, R. Dargel and G. Poli. The lipid peroxidation end product 4-hydroxy-2,3-nonenal up-regulates transforming growth factor beta1 expression in the macrophage lineage: a link between oxidative injury and fibrosclerosis. FASEB J. 11: 851-857, 1997.
    • (1997) FASEB J. , vol.11 , pp. 851-857
    • Leonarduzzi, G.1    Scavazza, A.2    Biasi, F.3    Chiarpotto, E.4    Camandola, S.5    Vogel, S.6    Dargel, R.7    Poli, G.8
  • 35
    • 0035680610 scopus 로고    scopus 로고
    • Activation of Kupffer cells during the course of carbon tetrachloride-induced liver injury and fibrosis in rats
    • Luckey, S.W. and D.R. Petersen. Activation of Kupffer cells during the course of carbon tetrachloride-induced liver injury and fibrosis in rats. Exp. Mol. Pathol. 71: 226-240, 2001.
    • (2001) Exp. Mol. Pathol. , vol.71 , pp. 226-240
    • Luckey, S.W.1    Petersen, D.R.2
  • 36
    • 7044271148 scopus 로고    scopus 로고
    • Hypoglycemic and hypolipidemic effects and antioxidant activity of fruit extracts from Lycium barbarum
    • Luo, Q., Y. Cai, J. Yan, M. Sun and H. Corke. Hypoglycemic and hypolipidemic effects and antioxidant activity of fruit extracts from Lycium barbarum. Life Sci. 76: 137-149, 2004.
    • (2004) Life Sci. , vol.76 , pp. 137-149
    • Luo, Q.1    Cai, Y.2    Yan, J.3    Sun, M.4    Corke, H.5
  • 37
    • 36949018944 scopus 로고    scopus 로고
    • Effect of Rehmannia glutinosa water extraction on insulin resistance and gene expression of resistin in type 2 diabetes mellitus rats
    • Lv, X.F., Q.Y. Meng and X.M. Guo. Effect of Rehmannia glutinosa water extraction on insulin resistance and gene expression of resistin in type 2 diabetes mellitus rats. Zhongguo Zhong Yao Za Zhi 32: 2182-2184, 2007.
    • (2007) Zhongguo Zhong Yao Za Zhi , vol.32 , pp. 2182-2184
    • Lv, X.F.1    Meng, Q.Y.2    Guo, X.M.3
  • 38
    • 0027509770 scopus 로고
    • A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates
    • Miller, N.J., C. Rice-Evans, M.J. Davies, V. Gopinathan and A. Milner. A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin. Sci. 84: 407-412, 1993.
    • (1993) Clin. Sci. , vol.84 , pp. 407-412
    • Miller, N.J.1    Rice-Evans, C.2    Davies, M.J.3    Gopinathan, V.4    Milner, A.5
  • 39
    • 0035131899 scopus 로고    scopus 로고
    • Anti-fibrotic effects of a hot-water extract from Salvia miltiorrhiza roots on liver fibrosis induced by biliary obstruction in rats
    • Nan, J.X., E.J. Park, H.C. Kang, P.H. Park, J.Y. Kim and D.H. Sohn. Anti-fibrotic effects of a hot-water extract from Salvia miltiorrhiza roots on liver fibrosis induced by biliary obstruction in rats. J. Pharm. Pharmacol. 53: 197-204, 2001.
    • (2001) J. Pharm. Pharmacol. , vol.53 , pp. 197-204
    • Nan, J.X.1    Park, E.J.2    Kang, H.C.3    Park, P.H.4    Kim, J.Y.5    Sohn, D.H.6
  • 40
    • 33846182255 scopus 로고    scopus 로고
    • Hepatocellular carcinoma development in cirrhosis
    • Okuda, H. Hepatocellular carcinoma development in cirrhosis. Best Pract. Res. Clin. Gastroenterol. 21: 161-173, 2007.
    • (2007) Best Pract. Res. Clin. Gastroenterol. , vol.21 , pp. 161-173
    • Okuda, H.1
  • 41
    • 0035831361 scopus 로고    scopus 로고
    • Structural characterization of the glycan part of glycoconjugate LbGp2 from Lycium barbarum L
    • Peng, X. and G. Tian. Structural characterization of the glycan part of glycoconjugate LbGp2 from Lycium barbarum L. Carbohydr. Res. 331: 95-99, 2001.
    • (2001) Carbohydr. Res. , vol.331 , pp. 95-99
    • Peng, X.1    Tian, G.2
  • 42
    • 0033013042 scopus 로고    scopus 로고
    • Water-extracted polysaccharides of selected cereals and influence of temperature on the extractability of polysaccharides in sorghum
    • Ramesh, H.P. and R.N. Tharanathan. Water-extracted polysaccharides of selected cereals and influence of temperature on the extractability of polysaccharides in sorghum. Food Chem. 64: 345-350, 1999.
    • (1999) Food Chem. , vol.64 , pp. 345-350
    • Ramesh, H.P.1    Tharanathan, R.N.2
  • 43
    • 0014098827 scopus 로고
    • Carbon tetrachloride hepatotoxicity
    • Recknagel, R.O. Carbon tetrachloride hepatotoxicity. Pharmacol. Rev. 19: 145-208, 1967.
    • (1967) Pharmacol. Rev. , vol.19 , pp. 145-208
    • Recknagel, R.O.1
  • 44
    • 0020614088 scopus 로고
    • A new direction in the study of carbon tetrachloride hepatotoxicity
    • Recknagel, R.O. A new direction in the study of carbon tetrachloride hepatotoxicity. Life Sci. 33: 401-408, 1983.
    • (1983) Life Sci. , vol.33 , pp. 401-408
    • Recknagel, R.O.1
  • 46
    • 0028111118 scopus 로고
    • Structural features and anti-complementary activity of rehmannan SA, a polysaccharide from the root of Rehmannia glutinosa
    • Tomoda, M., H. Miyamoto and N. Shimizu. Structural features and anti-complementary activity of rehmannan SA, a polysaccharide from the root of Rehmannia glutinosa. Chem. Pharma. Bull. (Tokyo) 42: 1666-1668, 1994.
    • (1994) Chem. Pharma. Bull. (Tokyo) , vol.42 , pp. 1666-1668
    • Tomoda, M.1    Miyamoto, H.2    Shimizu, N.3
  • 47
    • 77954586488 scopus 로고    scopus 로고
    • Hepatoprotective effect of Scoparia dulcis on carbon tetrachloride induced acute liver injury in mice
    • Tsai, J.C., W.H. Peng, T.H. Chiu, S.C. Huang, T.H. Huang, S.C. Lai, Z.R. Lai and C.Y. Lee. Hepatoprotective effect of Scoparia dulcis on carbon tetrachloride induced acute liver injury in mice. Am. J. Chin. Med. 38: 761-775, 2010.
    • (2010) Am. J. Chin. Med. , vol.38 , pp. 761-775
    • Tsai, J.C.1    Peng, W.H.2    Chiu, T.H.3    Huang, S.C.4    Huang, T.H.5    Lai, S.C.6    Lai, Z.R.7    Lee, C.Y.8
  • 48
    • 33845618610 scopus 로고    scopus 로고
    • Excess mortality of hepatocellular carcinoma and morbidity of liver cirrhosis and hepatitis in HCV-endemic areas in an HBV-endemic country: Geographic variations among 502 villages in southern Taiwan
    • Tsai, M.C., K.M. Kee, Y.D. Chen, L.C. Lin, L.S. Tsai, H.H. Chen and S.N. Lu. Excess mortality of hepatocellular carcinoma and morbidity of liver cirrhosis and hepatitis in HCV-endemic areas in an HBV-endemic country: geographic variations among 502 villages in southern Taiwan. J. Gastroenterol. Hepatol. 22: 92-98, 2007.
    • (2007) J. Gastroenterol. Hepatol. , vol.22 , pp. 92-98
    • Tsai, M.C.1    Kee, K.M.2    Chen, Y.D.3    Lin, L.C.4    Tsai, L.S.5    Chen, H.H.6    Lu, S.N.7
  • 49
    • 57349135217 scopus 로고    scopus 로고
    • Characterization of the anti-diabetic and antioxidant effects of Rehmannia glutinosa in streptozotocin-induced diabetic Wistar rats
    • Waisundara, V.Y., M. Huang, A. Hsu, D. Huang and B.K. Tan. Characterization of the anti-diabetic and antioxidant effects of Rehmannia glutinosa in streptozotocin-induced diabetic Wistar rats. Am. J. Chin. Med. 36: 1083-1104, 2008.
    • (2008) Am. J. Chin. Med. , vol.36 , pp. 1083-1104
    • Waisundara, V.Y.1    Huang, M.2    Hsu, A.3    Huang, D.4    Tan, B.K.5
  • 50
    • 0037256608 scopus 로고    scopus 로고
    • Hepatotoxicity and mechanism of action of haloalkanes: Carbon tetrachloride as a toxicological model
    • Weber, L.W., M. Boll and A. Stampfl. Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model. Crit. Rev. Toxicol. 33: 105-136, 2003.
    • (2003) Crit. Rev. Toxicol. , vol.33 , pp. 105-136
    • Weber, L.W.1    Boll, M.2    Stampfl, A.3
  • 51
    • 0030792840 scopus 로고    scopus 로고
    • Effects of low-molecular-weight Rehmannia glutinosa polysaccharides on p53 gene expression
    • Wei, X.L. and X.B. Ru. Effects of low-molecular-weight Rehmannia glutinosa polysaccharides on p53 gene expression. Zhongguo Yao Li Xue Bao 18: 471-474, 1997.
    • (1997) Zhongguo Yao Li Xue Bao , vol.18 , pp. 471-474
    • Wei, X.L.1    Ru, X.B.2
  • 52
    • 33745996622 scopus 로고
    • The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid
    • Woessner, J.F. The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch. Biochem. Biophys. 93: 440-447, 1961.
    • (1961) Arch. Biochem. Biophys. , vol.93 , pp. 440-447
    • Woessner, J.F.1
  • 53
    • 0027992229 scopus 로고
    • Hepatitis B and C viruses in the development of hepatocellular carcinoma
    • Yu, M.W. and C.J. Chen. Hepatitis B and C viruses in the development of hepatocellular carcinoma. Crit. Rev. Oncol. Hematol. 17: 71-91, 1994.
    • (1994) Crit. Rev. Oncol. Hematol. , vol.17 , pp. 71-91
    • Yu, M.W.1    Chen, C.J.2
  • 55
    • 33748520251 scopus 로고    scopus 로고
    • Protective effect of Rehmannia glutinosa on the cisplatin-induced damage of HEI-OC1 auditory cells through scavenging free radicals
    • Yu, H.H., S.J. Seo, Y.H. Kim, H.Y. Lee, R.K. Park, H.S. So, S.L. Jang and Y.O. You. Protective effect of Rehmannia glutinosa on the cisplatin-induced damage of HEI-OC1 auditory cells through scavenging free radicals. J. Ethnopharmacol. 107: 383-388, 2006b.
    • (2006) J. Ethnopharmacol. , vol.107 , pp. 383-388
    • Yu, H.H.1    Seo, S.J.2    Kim, Y.H.3    Lee, H.Y.4    Park, R.K.5    So, H.S.6    Jang, S.L.7    You, Y.O.8
  • 56
    • 0031261250 scopus 로고    scopus 로고
    • The injury of Xenopus laevis oocytes membrane and its acetylcholine receptor by free radical and the protection of Lycium barbarum polysaccharide
    • Zhang, B., X. Zhang and W. Li. The injury of Xenopus laevis oocytes membrane and its acetylcholine receptor by free radical and the protection of Lycium barbarum polysaccharide. Zhongguo Ying Yong Sheng Li Xue Za Zhi 13: 322-325, 1997.
    • (1997) Zhongguo Ying Yong Sheng Li Xue Za Zhi , vol.13 , pp. 322-325
    • Zhang, B.1    Zhang, X.2    Li, W.3
  • 57
    • 0347123329 scopus 로고    scopus 로고
    • Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism
    • Zhang, R., J. Zhou, Z. Jia, Y. Zhang and G. Gu. Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism. J. Ethnopharmacol. 90: 39-43, 2004.
    • (2004) J. Ethnopharmacol. , vol.90 , pp. 39-43
    • Zhang, R.1    Zhou, J.2    Jia, Z.3    Zhang, Y.4    Gu, G.5
  • 58
    • 34548498101 scopus 로고    scopus 로고
    • Catalpol ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by D-galactose
    • Zhang, X.L., B. Jiang, Z.B. Li, S. Hao and L.J. An. Catalpol ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by D-galactose. Pharmacol. Biochem. Behav. 88: 64-72, 2007.
    • (2007) Pharmacol. Biochem. Behav. , vol.88 , pp. 64-72
    • Zhang, X.L.1    Jiang, B.2    Li, Z.B.3    Hao, S.4    An, L.J.5
  • 59
    • 26044442367 scopus 로고    scopus 로고
    • Study on the extraction process of polysaccharide from Lycium barbarum
    • Zhi, F., W. Zheng, P. Chen and M. He. Study on the extraction process of polysaccharide from Lycium barbarum. Zhong Yao Cai 27: 948-950, 2004.
    • (2004) Zhong Yao Cai , vol.27 , pp. 948-950
    • Zhi, F.1    Zheng, W.2    Chen, P.3    He, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.