Tuning ligand density on intravenous hemostatic nanoparticles dramatically increases survival following blunt trauma

Biomacromolecules

Volumn 14, Issue 8, 2013, Pages 2790-2797

  Shoffstall, Andrew J ^a   Everhart, Lydia M ^a   Varley, Matthew E ^a   Soehnlen, Eric S ^a   Shick, Adam M ^a   Ustin, Jeffrey S ^b   Lavik, Erin B ^a  

^a Case Western Reserve University   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODISTRIBUTIONS; DOSE-RESPONSE STUDY; LIGAND CONCENTRATION; POLY LACTIC-CO-GLYCOLIC ACID; SYNTHETIC PLATELETS; TARGETED NANOPARTICLE; TARGETING LIGANDS; TARGETING PEPTIDES;

AMINO ACIDS; BLOOD SUBSTITUTES; COPOLYMERS; LIGANDS; MEDICAL APPLICATIONS; PEPTIDES; PLATELETS; POLYETHYLENE GLYCOLS;

NANOPARTICLES;

ARGINYLGLYCYLASPARTYLSERINE; COPOLYMER; FIBRINOGEN RECEPTOR; GLYCYLARGINYLGLYCYLASPARTYLSERINE; INTERCELLULAR ADHESION MOLECULE 1; LIGAND; MACROGOL; NANOPARTICLE; POLYGLACTIN; POLYLYSINE; GLYCYL-ARGINYL-GLYCYL-ASPARTYL-SERINE; HEMOSTATIC AGENT; MACROGOL DERIVATIVE; OLIGOPEPTIDE;

AMINO ACID ANALYSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY INJURY; ARTICLE; BLEEDING; BLOOD CLOTTING PARAMETERS; BLOOD CLOTTING TIME; BLUNT TRAUMA; CONTROLLED STUDY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG DOSE COMPARISON; DRUG MEGADOSE; FEMORAL ARTERY; HEMOSTASIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOLOGY; IN VITRO STUDY; KIDNEY; LIVER INJURY; LUNG; NANOMEDICINE; NONHUMAN; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SURVIVAL TIME; SYNTHESIS; THROMBOCYTE; THROMBOCYTE AGGREGATION INHIBITION; TISSUE DISTRIBUTION; ZETA POTENTIAL; ANIMAL; CHEMISTRY; HEMORRHAGE; INTRAVENOUS DRUG ADMINISTRATION; LIVER; LIVER DISEASES; PARTICLE SIZE; SPRAGUE DAWLEY RAT; THROMBOELASTOGRAPHY; ULTRASTRUCTURE; WOUNDS, NONPENETRATING;

ADMINISTRATION, INTRAVENOUS; ANIMALS; HEMORRHAGE; HEMOSTATICS; LIGANDS; LIVER; LIVER DISEASES; NANOPARTICLES; OLIGOPEPTIDES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; THROMBELASTOGRAPHY; TISSUE DISTRIBUTION; WOUNDS, NONPENETRATING;

EID: 84881605199     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm400619v     Document Type: Article

References (53)

1. Bhattacharyya, S.; Kudgus, R. A.; Bhattacharya, R.; Mukherjee, P. Pharm. Res. 2011, 28, 237-259
2. Danhier, F.; Ansorena, E.; Silva, J. M.; Coco, R.; Le Breton, A.; Preat, V. J. Controlled Release 2012, 161, 505-522
3. Prabhu, P.; Patravale, V. J Biomed Nanotechnol 2012, 8, 859-82
4. Thibault, G.; Tardif, P.; Lapalme, G. J. Pharmacol. Exp. Ther. 2001, 296, 690-696
5. Modery, C. L.; Ravikumar, M.; Wong, T. L.; Dzuricky, M. J.; Durongkaveroj, N.; Sen Gupta, A. Biomaterials 2011, 32, 9504-9514
6. Beer, J. H.; Springer, K. T.; Coller, B. S. Blood 1992, 79, 117-128
7. Ng, Q. K.; Sutton, M. K.; Soonsawad, P.; Xing, L.; Cheng, H.; Segura, T. Mol. Ther. 2009, 17, 828-836
8. Sancey, L.; Garanger, E.; Foillard, S.; Schoehn, G.; Hurbin, A.; Albiges-Rizo, C.; Boturyn, D.; Souchier, C.; Grichine, A.; Dumy, P.; Coll, J. L. Mol. Ther. 2009, 17, 837-843
9. Gu, F.; Zhang, L.; Teply, B. A.; Mann, N.; Wang, A.; Radovic-Moreno, A. F.; Langer, R.; Farokhzad, O. C. Proc. Natl. Acad. Sci. U. S. A. 2008, 105, 2586-2591
10. Garg, A.; Tisdale, A. W.; Haidari, E.; Kokkoli, E. Int. J. Pharm. 2009, 366, 201-210
11. Gindy, M. E.; Ji, S.; Hoye, T. R.; Panagiotopoulos, A. Z.; Prud'homme, R. K. Biomacromolecules 2008, 9, 2705-2711
12. Olivier, V.; Meisen, I.; Meckelein, B.; Hirst, T. R.; Peter-Katalinic, J.; Schmidt, M. A.; Frey, A. Bioconjugate Chem. 2003, 14, 1203-1208
13. Fakhari, A.; Baoum, A.; Siahaan, T. J.; Le, K. B.; Berkland, C. J. Pharm. Sci. 2011, 100, 1045-1056
14. Modery-Pawlowski, C. L.; Tian, L. L.; Ravikumar, M.; Wong, T. L.; Sen Gupta, A. Biomaterials 2013, 34, 3031-3041
15. Coller, B. S.; Kutok, J. L.; Scudder, L. E.; Galanakis, D. K.; West, S. M.; Rudomen, G. S.; Springer, K. T. J. Clin. Invest. 1993, 92, 2796-2806
16. Shoffstall, A. J.; Atkins, K. T.; Groynom, R. E.; Varley, M. E.; Everhart, L. M.; Lashof-Sullivan, M. M.; Martyn-Dow, B.; Butler, R. S.; Ustin, J. S.; Lavik, E. B. Biomacromolecules 2012, 13, 3850-3857
17. Bertram, J. P.; Williams, C. A.; Robinson, R.; Segal, S. S.; Flynn, N. T.; Lavik, E. B. Sci. Transl. Med. 2009, 1, 11ra22
18. Alving, B. M.; Reid, T. J.; Fratantoni, J. C.; Finlayson, J. S. Transfusion (Paris) 1997, 37, 866-876
19. Coller, B. S.; Springer, K. T.; Beer, J. H.; Mohandas, N.; Scudder, L. E.; Norton, K. J.; West, S. M. J. Clin. Invest. 1992, 89, 546-555
20. Levi, M.; Friederich, P. W.; Middleton, S.; de Groot, P. G.; Wu, Y. P.; Harris, R.; Biemond, B. J.; Heijnen, H. F.; Levin, J.; ten Cate, J. W. Nat. Med. 1999, 5, 107-111
21. Okamura, Y.; Maekawa, I.; Teramura, Y.; Maruyama, H.; Handa, M.; Ikeda, Y.; Takeoka, S. Bioconjugate Chem. 2005, 16, 1589-1596
22. Okamura, Y.; Eto, K.; Maruyama, H.; Handa, M.; Ikeda, Y.; Takeoka, S. Nanomedicine 2010, 6, 391-396
23. Blajchman, M. A. Vox Sang. 2000, 78 (Suppl 2) 183-186
24. Blajchman, M. A. Transfus. Clin. Biol. 2001, 8, 267-271
25. Davies, A. R.; Judge, H. M.; May, J. A.; Glenn, J. R.; Heptinstall, S. Platelets 2002, 13, 197-205
26. Ravikumar, M.; Modery, C. L.; Wong, T. L.; Dzuricky, M.; Sen Gupta, A. Bioconjugate Chem. 2012, 23, 1266-1275
27. Nishikawa, K.; Hagisawa, K.; Kinoshita, M.; Shono, S.; Katsuno, S.; Doi, M.; Yanagawa, R.; Suzuki, H.; Iwaya, K.; Saitoh, D.; Sakamoto, T.; Seki, S.; Takeoka, S.; Handa, M. J. Thromb. Haemostasis 2012, 10, 2137-2148
28. Ravikumar, M.; Modery, C. L.; Wong, T. L.; Gupta, A. S. Biomacromolecules 2012, 13, 1495-1502
29. Kauvar, D. S.; Lefering, R.; Wade, C. E. J. Trauma 2006, 60 (6 Suppl) S3-11
30. Holcomb, J. B.; McMullin, N. R.; Pearse, L.; Caruso, J.; Wade, C. E.; Oetjen-Gerdes, L.; Champion, H. R.; Lawnick, M.; Farr, W.; Rodriguez, S.; Butler, F. K. Ann. Surg. 2007, 245, 986-991
31. Champion, H. R.; Bellamy, R. F.; Roberts, C. P.; Leppaniemi, A. J. Trauma 2003, 54 (5 Suppl) S13-9
32. Johannigman, J.; Rhee, P.; Jenkins, D.; Holcomb, J. Modern Combat Casualty Care. In Trauma, 7 th ed.; Mattox, K. L.; Moore, E. E.; Feliciano, D. V., Eds.; McGraw-Hill Professional: New York, 2012.
33. Kelly, J. F.; Ritenour, A. E.; McLaughlin, D. F.; Bagg, K. A.; Apodaca, A. N.; Mallak, C. T.; Pearse, L.; Lawnick, M. M.; Champion, H. R.; Wade, C. E.; Holcomb, J. B. J. Trauma 2008, 64 (2 Suppl) S21-6
34. 2008, discussion S26-7.
35. Clifford, C. C. Mil. Med. 2004, 169 (12 Suppl) 8-10
36. Lavik, E. B.; Hrkach, J. S.; Lotan, N.; Nazarov, R.; Langer, R. J. Biomed. Mater. Res. 2001, 58, 291-294
37. Bertram, J. P.; Jay, S. M.; Hynes, S. R.; Robinson, R.; Criscione, J. M.; Lavik, E. B. Acta Biomater. 2009, 5, 2860-2871
38. Holcomb, J. B.; McClain, J. M.; Pusateri, A. E.; Beall, D.; Macaitis, J. M.; Harris, R. A.; MacPhee, M. J.; Hess, J. R. J. Trauma 2000, 49, 246-250
39. Ryan, K. L.; Cortez, D. S.; Dick, E. J., Jr.; Pusateri, A. E. Resuscitation 2006, 70, 133-144
40. Matsuoka, T.; Wisner, D. H. J. Trauma 1996, 41, 439-445
41. Matsuoka, T.; Hildreth, J.; Wisner, D. H. J. Trauma 1995, 39, 674-680
42. Siller-Matula, J. M.; Plasenzotti, R.; Spiel, A.; Quehenberger, P.; Jilma, B. Thromb. Haemostasis 2008, 100, 397-404
43. Probst, R. J.; Lim, J. M.; Bird, D. N.; Pole, G. L.; Sato, A. K.; Claybaugh, J. R. J. Am. Assoc. Lab. Anim. Sci. 2006, 45, 49-52
44. Nunez, T. C.; Cotton, B. A. Curr. Opin. Crit. Care 2009, 15, 536-541
45. Martinowitz, U.; Zaarur, M.; Yaron, B. L.; Blumenfeld, A.; Martonovits, G. Mil. Med. 2004, 169 (12 Suppl) 16-8
46. Hess, J. R.; Holcomb, J. B. Transfus. Med. 2008, 18, 143-150
47. Grislain, L.; Couvreur, P.; Lenaerts, V.; Roland, M.; Deprezdecampeneere, D.; Speiser, P. Int. J. Pharm. 1983, 15, 335-345
48. Martin, F. J.; Melnik, K.; West, T.; Shapiro, J.; Cohen, M.; Boiarski, A. A.; Ferrari, M. Drugs R&D 2005, 6, 71-81
49. Decuzzi, P.; Godin, B.; Tanaka, T.; Lee, S. Y.; Chiappini, C.; Liu, X.; Ferrari, M. J. Controlled Release 2010, 141, 320-327
50. Guo, G.; Kang, Y.; Li, X.; Cai, Z. H.; Chen, J. H.; Wang, G.; Pei, G. X. Chin. J. Traumatol. 2007, 10, 237-241
51. Knudson, M. M.; Ikossi, D. G.; Khaw, L.; Morabito, D.; Speetzen, L. S. Ann. Surg. 2004, 240, 490-6
52. 2004, discussion 496-8.
53. Ali, M. M.; Zale, S. E. Cancer Cell Targeting Using Nanoparticles. U.S. Patent 8,236,330, Mar 30, 2007.