Fibrinogen γ-chain peptide-coated, ADP-encapsulated liposomes rescue thrombocytopenic rabbits from non-compressible liver hemorrhage

Journal of Thrombosis and Haemostasis

Volumn 10, Issue 10, 2012, Pages 2137-2148

  Nishikawa, K ^a   Hagisawa, K ^a   Kinoshita, M ^a   Shono, S ^a   Katsuno, S ^b   Doi, M ^b   Yanagawa, R ^a   Suzuki, H ^c   Iwaya, K ^a   Saitoh, D ^a   Sakamoto, T ^a   Seki, S ^a   Takeoka, S ^b   Handa, M ^d  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^b WASEDA UNIVERSITY   (Japan)

^c NIPPON MEDICAL SCHOOL   (Japan)

^d KEIO UNIVERSITY   (Japan)

Author keywords

Hemostasis; Liver hemorrhage; Nanotechnology; Platelet substitute; Rabbits; Thrombocytopenia

Indexed keywords

ADENOSINE DIPHOSPHATE; FIBRINOGEN GAMMA CHAIN PEPTIDE; FIBRINOGEN RECEPTOR; LIPOSOME; PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLEEDING TIME; ERYTHROCYTE TRANSFUSION; EXCHANGE BLOOD TRANSFUSION; KIDNEY; LIVER HEMORRHAGE; LIVER HISTOLOGY; LIVER INJURY; LUNG; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RABBIT; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTE POOR PLASMA; THROMBOCYTE RICH PLASMA; THROMBOCYTOPENIA;

ACUTE DISEASE; ADENOSINE DIPHOSPHATE; ANIMALS; BLOOD COAGULATION TESTS; BLOOD PLATELETS; DISEASE MODELS, ANIMAL; FEASIBILITY STUDIES; FIBRINOGEN; HEMORRHAGE; HEMOSTASIS; HEMOSTATICS; LIPOSOMES; LIVER DISEASES; MALE; MICROSCOPY, IMMUNOELECTRON; OLIGOPEPTIDES; PLATELET AGGREGATION; PLATELET COUNT; RABBITS; THROMBOCYTOPENIA; TIME FACTORS; WOUNDS, PENETRATING;

EID: 84866840260     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2012.04889.x     Document Type: Article

References (30)

1. Sauaia A, Moore FA, Moore EE, Moser KS, Brennan R, Read RA, Pons PT. Epidemiology of trauma deaths: a reassessment. J Trauma 1995; 38: 185-93.
2. Holcomb JB, McMullin NR, Pearse L, Caruso J, Wade CE, Oetjen-Gerdes L, Champion HR, Lawnick M, Farr W, Rodriguez S, Butler FK. Causes of death in US Special Operations Forces in the global war on terrorism: 2001-2004. Ann Surg 2007; 245: 986-91.
3. Como JJ, Dutton RP, Scalea TM, Edelman BB, Hess JR. Blood transfusion rates in the care of acute trauma. Transfusion 2004; 44: 809-13.
4. Gonzalez EA, Moore FA, Holcomb JB, Miller CC, Kozar RA, Todd SR, Cocanour CS, Balldin BC, McKinley BA. Fresh frozen plasma should be given earlier to patients requiring massive transfusion. J Trauma 2007; 62: 112-19.
5. Ho AM, Karmakar MK, Dion PW. Are we giving enough coagulation factors during major trauma resuscitation? Am J Surg 2005; 190: 479-84.
6. Cinat ME, Wallace WC, Nastanski F, West J, Sloan S, Ocariz J, Wilson SE. Improved survival following massive transfusion in patients who have undergone trauma. Arch Surg 1999; 134: 964-8; discussion 8-70.
7. Johansson PI, Stensballe J, Rosenberg I, Hilslov TL, Jorgensen L, Secher NH. Proactive administration of platelets and plasma for patients with a ruptured abdominal aortic aneurysm: evaluating a change in transfusion practice. Transfusion 2007; 47: 593-8.
8. Stinger HK, Spinella PC, Perkins JG, Grathwohl KW, Salinas J, Martini WZ, Hess JR, Dubick MA, Simon CD, Beekley AC, Wolf SE, Wade CE, Holcomb JB. The ratio of fibrinogen to red cells transfused affects survival in casualties receiving massive transfusions at an army combat support hospital. J Trauma 2008; 64: S79-85.
9. Kirkman E, Watts S, Hodgetts T, Mahoney P, Rawlinson S, Midwinter M. A proactive approach to the coagulopathy of trauma: the rationale and guidelines for treatment. J R Army Med Corps 2007; 153: 302-6.
10. Miller RD, Robbins TO, Tong MJ, Barton SL. Coagulation defects associated with massive blood transfusions. Ann Surg 1971; 174: 794-801.
11. Miller RD. Massive blood transfusions: the impact of Vietnam military data on modern civilian transfusion medicine. Anesthesiology 2009; 110: 1412-16.
12. Blajchman MA. Substitutes for success. Nat Med 1999; 5: 17-18.
13. Vamvakas E. Risk-reduction strategies for platelet transfusion in the United States. ScientificWorldJournal 2011; 11: 624-40.
14. Nogami Y, Kinoshita M, Takase B, Ogata Y, Saitoh D, Kikuchi M, Ishihara M, Maehara T. Liposome-encapsulated hemoglobin transfusion rescues rats undergoing progressive hemodilution from lethal organ hypoxia without scavenging nitric oxide. Ann Surg 2008; 248: 310-19.
15. Bertram JP, Williams CA, Robinson R, Segal SS, Flynn NT, Lavik EB. Intravenous hemostat: nanotechnology to halt bleeding. Sci Transl Med 2009; 1: 11-22.
16. Levi M, Friederich PW, Middleton S, de Groot PG, Wu YP, Harris R, Biemond BJ, Heijnen HF, Levin J, ten Cate JW. Fibrinogen-coated albumin microcapsules reduce bleeding in severely thrombocytopenic rabbits. Nat Med 1999; 5: 107-11.
17. Takeoka S, Okamura Y, Teramura Y, Watanabe N, Suzuki H, Tsuchida E, Handa M, Ikeda Y. Function of fibrinogen gamma-chain dodecapeptide-conjugated latex beads under flow. Biochem Biophys Res Commun 2003; 312: 773-9.
18. Andrieux A, Hudry-Clergeon G, Ryckewaert JJ, Chapel A, Ginsberg MH, Plow EF, Marguerie G. Amino acid sequences in fibrinogen mediating its interaction with its platelet receptor, GPIIbIIIa. J Biol Chem 1989; 264: 9258-65.
19. Weisel JW, Nagaswami C, Vilaire G, Bennett JS. Examination of the platelet membrane glycoprotein IIb-IIIa complex and its interaction with fibrinogen and other ligands by electron microscopy. J Biol Chem 1992; 267: 16637-43.
20. Okamura Y, Katsuno S, Suzuki H, Maruyama H, Handa M, Ikeda Y, Takeoka S. Release abilities of adenosine diphosphate from phospholipid vesicles with different membrane properties and their hemostatic effects as a platelet substitute. J Control Release 2010; 148: 373-9.
21. Okamura Y, Takeoka S, Eto K, Maekawa I, Fujie T, Maruyama H, Ikeda Y, Handa M. Development of fibrinogen gamma-chain peptide-coated, adenosine diphosphate-encapsulated liposomes as a synthetic platelet substitute. J Thromb Haemost 2009; 7: 470-7.
22. Suzuki H, Okamura Y, Ikeda Y, Takeoka S, Handa M. Ultrastructural analysis of thrombin-induced interaction between human platelets and liposomes carrying fibrinogen gamma-chain dodecapeptide as a synthetic platelet substitute. Thromb Res 2011; 128: 552-9.
23. Tokuyasu KT. Use of poly(vinylpyrrolidone) and poly(vinyl alcohol) for cryoultramicrotomy. Histochem J 1989; 21: 163-71.
24. Suzuki H, Nakamura S, Itoh Y, Tanaka T, Yamazaki H, Tanoue K. Immunocytochemical evidence for the translocation of alpha-granule membrane glycoprotein IIb/IIIa (integrin alpha IIb beta 3) of human platelets to the surface membrane during the release reaction. Histochemistry 1992; 97: 381-8.
25. Hiippala ST, Myllyla GJ, Vahtera EM. Hemostatic factors and replacement of major blood loss with plasma-poor red cell concentrates. Anesth Analg 1995; 81: 360-5.
26. Malone DL, Hess JR, Fingerhut A. Massive transfusion practices around the globe and a suggestion for a common massive transfusion protocol. J Trauma 2006; 60: S91-6.
27. Spinella PC, Perkins JG, McLaughlin DF, Niles SE, Grathwohl KW, Beekley AC, Salinas J, Mehta S, Wade CE, Holcomb JB. The effect of recombinant activated factor VII on mortality in combat-related casualties with severe trauma and massive transfusion. J Trauma 2008; 64: 286-93; discussion 93-4.
28. Wade CE, Eastridge BJ, Jones JA, West SA, Spinella PC, Perkins JG, Dubick MA, Blackbourne LH, Holcomb JB. Use of recombinant factor VIIa in US military casualties for a five-year period. J Trauma 2010; 69: 353-9.
29. Hawksworth JS, Elster EA, Fryer D, Sheppard F, Morthole V, Krishnamurthy G, Tomori T, Brown TS, Tadaki DK. Evaluation of lyophilized platelets as an infusible hemostatic agent in experimental non-compressible hemorrhage in swine. J Thromb Haemost 2009; 7: 1663-71.
30. Tokutomi K, Tagawa T, Korenaga M, Chiba M, Asai T, Watanabe N, Takeoka S, Handa M, Ikeda Y, Oku N. Decoration of fibrinogen gamma-chain peptide on adenosine diphosphate-encapsulated liposomes enhances binding of the liposomes to activated platelets. Int J Pharm 2011; 407: 151-7.