Histological examination of collagen and proteoglycan changes in osteoarthritic menisci

Open Rheumatology Journal

Volumn 6, Issue 1, 2012, Pages 24-32

  Sun, Yubo ^a   Mauerhan, David R ^a   Kneisl, Jeffrey S ^a   James Norton, H ^a   Zinchenko, Natalia ^a   Ingram, Jane ^a   Hanley, Edward N ^a   Gruber, Helen E ^a  

^a CAROLINAS MEDICAL CENTER   (United States)

Author keywords

Aggrecan; Collagen I; Collagen II; Meniscus; Osteoarthritis; Proteoglycan

Indexed keywords

AGGRECAN; ALCIAN BLUE; COLLAGEN TYPE 1; COLLAGEN TYPE 2; DYE; EOSIN; HEMATOXYLIN; PROTEOGLYCAN; SAFRANIN O; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOCHEMISTRY; IMMUNOHISTOCHEMISTRY; KNEE ARTHROPLASTY; KNEE MENISCUS; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

EID: 84860696591     PISSN: None     EISSN: 18743129     Source Type: Journal    
DOI: 10.2174/1874312901206010024     Document Type: Article

References (26)

1. Noble J, Hamblen DL. The pathology of the degenerate meniscus lesion. J Bone Joint Surg Br 1975; 57: 180-186.
2. Englund M, Guermazi A, Gale D, et al. Incidental meniscal findings on knee MRI in middle-aged and elderly persons. N Engl J Med 2008; 359: 1108-1115.
3. Chan WP, Lang P, Stevens MP, et al. Osteoarthritis of the knee: comparison of radiography, CT, and MR imaging to assess extent and severity. Am J Roentgenol 1991; 157: 799-806.
4. Bennett LD, Buckland-Wright JC. Meniscal and articular cartilage changes in knee osteoarthritis: a cross-sectional double-contrast macroradiographic study. Rheumatology 2002; 41: 917-923.
5. Englund M. Meniscal tear--a feature of osteoarthritis. Acta Orthop Scand 2004; 75: 1-45.
6. Englund M, Guermazi A, Roemer FW, et al. Meniscal tear in knees without surgery and the development of radiographic osteoarthritis among middle-aged and elderly persons: the Multicenter Osteoarthritis Study. Arthritis Rheum 2009; 60: 831-839.
7. Fukuta S, Kuge A, Korai F. Clinical significance of meniscal abnormalities on magnetic resonance imaging in an older population. Knee 2009; 16: 187-190.
8. Crema MD, Guermazi A, Li L, et al. The association of prevalent medial meniscal pathology with cartilage loss in the medial tibiofemoral compartment over a 2-year period. Osteoarthritis Cartilage 2010; 18: 336-343.
9. Kai B, Mann SA, King C, Forster BB. Integrity of articular cartilage on T2 mapping associated with meniscal signal change. Eur J Radiol 2011; 79: 421-427.
10. Kan A, Oshida M, Oshida S, Imada M, Nakagawa T, Okinaga S. Anatomical significance of a posterior horn of medial meniscus: the relationship between its radial tear and cartilage degradation of joint surface. Sports Med Arthrosc Rehabil Ther Technol 2010; 2:1.
11. Sun Y, Mauerhan DR, Honeycutt PR, et al. Calcium deposition in osteoarthritic menisci and meniscal cell culture. Arthritis Res Ther 2010; 12: R56.
12. Sun Y, Mauerhan DR, Honeycutt PR, et al. Analysis of meniscal degeneration and meniscal gene expression. BMC Musculoskelet Disord 2010; 11: 19.
13. Squires GR, Okouneff S, Ionescu M, Poole AR. The pathobiology of focal lesion development in aging human articular cartilage and molecular matrix changes characteristic of osteoarthritis. Arthritis Rheum 2003; 48: 1261-1270.
14. Lahm A, Mrosek E, Spank H, et al. Changes in content and synthesis of collagen types and proteoglycans in osteoarthritis of the knee joint and comparison of quantitative analysis with Photoshop-based image analysis. Arch Orthop Trauma Surg 2010; 130: 557-564.
15. Saarakkala S, Julkunen P, Kiviranta P, Makitalo J, Jurvelin JS, Korhonen RK. Depth-wise progression of osteoarthritis in human articular cartilage: investigation of composition, structure and biomechanics. Osteoarthritis Cartilage 2010; 18: 73-81.
16. Kambic HE, McDevitt CA. Spatial organization of types I and II collagen in the canine meniscus. J Orthop Res 2005; 23: 142-149.
17. Videman T, Eronen I, Friman C, Langenskiold A. Glycosaminoglycan metabolism of the medial meniscus, the medial collateral ligament and the hip joint capsule in experimental osteoarthritis caused by immobilization of the rabbit knee. Acta Orthop Scand 1979; 50: 465-470.
18. Djurasovic M, Aldridge JW, Grumbles R, Rosenwasser MP, Howell D, Ratcliffe A. Knee joint immobilization decreases aggrecan gene expression in the meniscus. Am J Sports Med 1998; 26; 460-466.
19. Adams ME, Billingham ME, Muir H. The glycosaminoglycans in menisci in experimental and natural osteoarthritis. Arthritis Rheum 1983; 26: 69-76.
20. Peters TJ, Smillie IS. Studies on the chemical composition of the menisci of the knee joint with special reference to the horizontal cleavage lesion. Clin Orthop Relat Res 1972; 86: 245-252.
21. Herwig J, Egner E, Buddecke E. Chemical changes of human knee joint menisci in various stages of degeneration. Ann Rheum Dis 1984; 43: 635-640.
22. Ghosh P, Ingman AM, Taylor TK. Variations in collagen, non-collagenous proteins, and hexosamine in menisci derived from osteoarthritic and rheumatoid arthritic knee joints. J Rheumatol 1975; 2: 100-107.
23. Bhattacharyya T, Gale D, Dewire P, et al. The clinical importance of meniscal tears demonstrated by magnetic resonance imaging in osteoarthritis of the knee. J Bone Joint Surg Am 2003; 85-A: 4-9.
24. Berthiaume MJ, Raynauld JP, Martel-Pelletier J, et al. Meniscal tear and extrusion are strongly associated with progression of symptomatic knee osteoarthritis as assessed by quantitative magnetic resonance imaging. Ann Rheum Dis 2005; 64: 556-563.
25. Hunter DJ, Zhang YQ, Niu JB, et al. The association of meniscal pathologic changes with cartilage loss in symptomatic knee osteoarthritis. Arthritis Rheum 2006; 54: 795-801.
26. Roemer FW, Zhang Y, Niu J, et al. Tibiofemoral joint osteoarthritis: risk factors for MR-depicted fast cartilage loss over a 30-month period in the multicenter osteoarthritis study. Radiology 2009; 252: 772-780