메뉴 건너뛰기




Volumn 438, Issue 1, 2013, Pages 97-102

Targeted deletion of Kif18a protects from colitis-associated colorectal (CAC) tumors in mice through impairing Akt phosphorylation

Author keywords

Akt; AOM DSS model; Colitis associated cancer; Kinesin 8 Kif18a; Knock out mice; Tumorigenesis

Indexed keywords

AZOXYMETHANE; DOCUSATE SODIUM; KIF18A PROTEIN; KINESIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 84881548206     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.07.032     Document Type: Article
Times cited : (24)

References (36)
  • 1
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • Jordan M.A., Wilson L. Microtubules as a target for anticancer drugs. Nat. Rev. Cancer 2004, 4:253-265.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 2
    • 0345688612 scopus 로고    scopus 로고
    • Mechanisms of taxol resistance related to microtubules
    • Orr G.A., Verdier-Pinard P., McDaid H., Horwitz S.B. Mechanisms of taxol resistance related to microtubules. Oncogene 2003, 22:7280-7295.
    • (2003) Oncogene , vol.22 , pp. 7280-7295
    • Orr, G.A.1    Verdier-Pinard, P.2    McDaid, H.3    Horwitz, S.B.4
  • 3
    • 77649191871 scopus 로고    scopus 로고
    • Microtubules and resistance to tubulin-binding agents
    • Kavallaris M. Microtubules and resistance to tubulin-binding agents. Nat. Rev. Cancer 2010, 10:194-204.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 194-204
    • Kavallaris, M.1
  • 4
    • 0035433029 scopus 로고    scopus 로고
    • Past and future of the mitotic spindle as an oncology target
    • Wood K.W., Cornwell W.D., Jackson J.R. Past and future of the mitotic spindle as an oncology target. Curr. Opin. Pharmacol. 2001, 1:370-377.
    • (2001) Curr. Opin. Pharmacol. , vol.1 , pp. 370-377
    • Wood, K.W.1    Cornwell, W.D.2    Jackson, J.R.3
  • 7
    • 70349437416 scopus 로고    scopus 로고
    • Kinesin superfamily motor proteins and intracellular transport
    • Hirokawa N., Noda Y., Tanaka Y., Niwa S. Kinesin superfamily motor proteins and intracellular transport. Nat. Rev. Mol. Cell Biol. 2009, 10:682-696.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 682-696
    • Hirokawa, N.1    Noda, Y.2    Tanaka, Y.3    Niwa, S.4
  • 8
    • 77949540170 scopus 로고    scopus 로고
    • How kinesin motor proteins drive mitotic spindle function: lessons from molecular assays
    • Wordeman L. How kinesin motor proteins drive mitotic spindle function: lessons from molecular assays. Semin. Cell Dev. Biol. 2010, 21:260-268.
    • (2010) Semin. Cell Dev. Biol. , vol.21 , pp. 260-268
    • Wordeman, L.1
  • 9
    • 24344465919 scopus 로고    scopus 로고
    • Analysis of the kinesin superfamily: insights into structure and function
    • Miki H., Okada Y., Hirokawa N. Analysis of the kinesin superfamily: insights into structure and function. Trends Cell Biol. 2005, 15:467-476.
    • (2005) Trends Cell Biol. , vol.15 , pp. 467-476
    • Miki, H.1    Okada, Y.2    Hirokawa, N.3
  • 10
    • 33746328114 scopus 로고    scopus 로고
    • KIF14 mRNA expression is a predictor of grade and outcome in breast cancer
    • Corson T.W., Gallie B.L. KIF14 mRNA expression is a predictor of grade and outcome in breast cancer. Int. J. Cancer 2006, 119:1088-1094.
    • (2006) Int. J. Cancer , vol.119 , pp. 1088-1094
    • Corson, T.W.1    Gallie, B.L.2
  • 12
    • 34547882734 scopus 로고    scopus 로고
    • Clinicopathological and biological significance of mitotic centromere-associated kinesin overexpression in human gastric cancer
    • Nakamura Y., Tanaka F., Haraguchi N., Mimori K., Matsumoto T., Inoue H., Yanaga K., Mori M. Clinicopathological and biological significance of mitotic centromere-associated kinesin overexpression in human gastric cancer. Br. J. Cancer 2007, 97:543-549.
    • (2007) Br. J. Cancer , vol.97 , pp. 543-549
    • Nakamura, Y.1    Tanaka, F.2    Haraguchi, N.3    Mimori, K.4    Matsumoto, T.5    Inoue, H.6    Yanaga, K.7    Mori, M.8
  • 13
    • 11244284210 scopus 로고    scopus 로고
    • Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell
    • Taniuchi K., Nakagawa H., Nakamura T., Eguchi H., Ohigashi H., Ishikawa O., Katagiri T., Nakamura Y. Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell. Cancer Res. 2005, 65:105-112.
    • (2005) Cancer Res. , vol.65 , pp. 105-112
    • Taniuchi, K.1    Nakagawa, H.2    Nakamura, T.3    Eguchi, H.4    Ohigashi, H.5    Ishikawa, O.6    Katagiri, T.7    Nakamura, Y.8
  • 19
    • 76749091008 scopus 로고    scopus 로고
    • The kinesin-8 Kif18A dampens microtubule plus-end dynamics
    • Du Y., English C.A., Ohi R. The kinesin-8 Kif18A dampens microtubule plus-end dynamics. Curr. Biol. 2010, 20:374-380.
    • (2010) Curr. Biol. , vol.20 , pp. 374-380
    • Du, Y.1    English, C.A.2    Ohi, R.3
  • 20
    • 46049112667 scopus 로고    scopus 로고
    • Kinesin-8 molecular motors: putting the brakes on chromosome oscillations
    • Gardner M.K., Odde D.J., Bloom K. Kinesin-8 molecular motors: putting the brakes on chromosome oscillations. Trends Cell Biol. 2008, 18:307-310.
    • (2008) Trends Cell Biol. , vol.18 , pp. 307-310
    • Gardner, M.K.1    Odde, D.J.2    Bloom, K.3
  • 21
    • 33947111858 scopus 로고    scopus 로고
    • The human kinesin Kif18A is a motile microtubule depolymerase essential for chromosome congression
    • Mayr M.I., Hummer S., Bormann J., Gruner T., Adio S., Woehlke G., Mayer T.U. The human kinesin Kif18A is a motile microtubule depolymerase essential for chromosome congression. Curr. Biol. 2007, 17:488-498.
    • (2007) Curr. Biol. , vol.17 , pp. 488-498
    • Mayr, M.I.1    Hummer, S.2    Bormann, J.3    Gruner, T.4    Adio, S.5    Woehlke, G.6    Mayer, T.U.7
  • 22
    • 80052230972 scopus 로고    scopus 로고
    • A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A
    • Stumpff J., Du Y., English C.A., Maliga Z., Wagenbach M., Asbury C.L., Wordeman L., Ohi R. A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A. Mol. Cell 2011, 43:764-775.
    • (2011) Mol. Cell , vol.43 , pp. 764-775
    • Stumpff, J.1    Du, Y.2    English, C.A.3    Maliga, Z.4    Wagenbach, M.5    Asbury, C.L.6    Wordeman, L.7    Ohi, R.8
  • 23
    • 38849201167 scopus 로고    scopus 로고
    • The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment
    • Stumpff J., von Dassow G., Wagenbach M., Asbury C., Wordeman L. The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment. Dev. Cell 2008, 14:252-262.
    • (2008) Dev. Cell , vol.14 , pp. 252-262
    • Stumpff, J.1    von Dassow, G.2    Wagenbach, M.3    Asbury, C.4    Wordeman, L.5
  • 24
    • 84860893886 scopus 로고    scopus 로고
    • Kif18A and chromokinesins confine centromere movements via microtubule growth suppression and spatial control of kinetochore tension
    • Stumpff J., Wagenbach M., Franck A., Asbury C.L., Wordeman L. Kif18A and chromokinesins confine centromere movements via microtubule growth suppression and spatial control of kinetochore tension. Dev. Cell 2012, 22:1017-1029.
    • (2012) Dev. Cell , vol.22 , pp. 1017-1029
    • Stumpff, J.1    Wagenbach, M.2    Franck, A.3    Asbury, C.L.4    Wordeman, L.5
  • 25
    • 34247394226 scopus 로고    scopus 로고
    • Chromosome congression: the kinesin-8-step path to alignment
    • Stumpff J., Wordeman L. Chromosome congression: the kinesin-8-step path to alignment. Curr. Biol. 2007, 17:R326-328.
    • (2007) Curr. Biol. , vol.17
    • Stumpff, J.1    Wordeman, L.2
  • 26
  • 32
    • 34548162712 scopus 로고    scopus 로고
    • An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression
    • Neufert C., Becker C., Neurath M.F. An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression. Nat. Protoc. 2007, 2:1998-2004.
    • (2007) Nat. Protoc. , vol.2 , pp. 1998-2004
    • Neufert, C.1    Becker, C.2    Neurath, M.F.3
  • 35
    • 13844273087 scopus 로고    scopus 로고
    • PI3K-Akt pathway: its functions and alterations in human cancer
    • Osaki M., Oshimura M., Ito H. PI3K-Akt pathway: its functions and alterations in human cancer. Apoptosis 2004, 9:667-676.
    • (2004) Apoptosis , vol.9 , pp. 667-676
    • Osaki, M.1    Oshimura, M.2    Ito, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.