Kif18A uses a microtubule binding site in the tail for plus-end localization and spindle length regulation

Current Biology

Volumn 21, Issue 17, 2011, Pages 1500-1506

  Weaver, Lesley N ^a,c   Ems McClung, Stephanie C ^a   Stout, Jane R ^a   Leblanc, Chantal ^a   Shaw, Sidney L ^a   Gardner, Melissa K ^b,c   Walczak, Claire E ^a  

^a INDIANA UNIVERSITY   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c MARINE BIOLOGICAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KIF18A PROTEIN, HUMAN; KINESIN;

ARTICLE; BINDING SITE; BIOLOGICAL MODEL; CELL NUCLEUS; CHROMOSOME POSITIONING; COMPUTER SIMULATION; GENETICS; HELA CELL; HUMAN; METABOLISM; MICROTUBULE; MITOSIS; MITOSIS SPINDLE; PHYSIOLOGY; PROTEIN BINDING;

BINDING SITES; CELL NUCLEUS; CHROMOSOME POSITIONING; COMPUTER SIMULATION; HELA CELLS; HUMANS; KINESIN; MICROTUBULES; MITOSIS; MITOTIC SPINDLE APPARATUS; MODELS, BIOLOGICAL; PROTEIN BINDING;

EID: 80052209594     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2011.08.005     Document Type: Article

References (27)

1. G. Goshima, and J.M. Scholey Control of mitotic spindle length Annu. Rev. Cell Dev. Biol. 26 2010 21 57
2. G. Goshima, R. Wollman, N. Stuurman, J.M. Scholey, and R.D. Vale Length control of the metaphase spindle Curr. Biol. 15 2005 1979 1988 (Pubitemid 41654610)
3. M.L. Gupta Jr., P. Carvalho, D.M. Roof, and D. Pellman Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle Nat. Cell Biol. 8 2006 913 923 (Pubitemid 44314722)
4. M.I. Mayr, S. Hümmer, J. Bormann, T. Grüner, S. Adio, G. Woehlke, and T.U. Mayer The human kinesin Kif18A is a motile microtubule depolymerase essential for chromosome congression Curr. Biol. 17 2007 488 498 (Pubitemid 46401386)
5. M.S. Savoian, M.K. Gatt, M.G. Riparbelli, G. Callaini, and D.M. Glover Drosophila Klp67A is required for proper chromosome congression and segregation during meiosis I J. Cell Sci. 117 2004 3669 3677 (Pubitemid 39206406)
6. M.S. Savoian, and D.M. Glover Drosophila Klp67A binds prophase kinetochores to subsequently regulate congression and spindle length J. Cell Sci. 123 2010 767 776
7. J. Stumpff, G. von Dassow, M. Wagenbach, C. Asbury, and L. Wordeman The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment Dev. Cell 14 2008 252 262 (Pubitemid 351189173)
8. V. Varga, J. Helenius, K. Tanaka, A.A. Hyman, T.U. Tanaka, and J. Howard Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner Nat. Cell Biol. 8 2006 957 962 (Pubitemid 44314726)
9. K. Jaqaman, E.M. King, A.C. Amaro, J.R. Winter, J.F. Dorn, H.L. Elliott, N. McHedlishvili, S.E. McClelland, I.M. Porter, and M. Posch Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases J. Cell Biol. 188 2010 665 679
10. L.E. Hough, A. Schwabe, M.A. Glaser, J.R. McIntosh, and M.D. Betterton Microtubule depolymerization by the Kinesin-8 motor Kip3p: A mathematical model Biophys. J. 96 2009 3050 3064
11. V. Varga, C. Leduc, V. Bormuth, S. Diez, and J. Howard Kinesin-8 motors act cooperatively to mediate length-dependent microtubule depolymerization Cell 138 2009 1174 1183
12. Y. Du, C.A. English, and R. Ohi The kinesin-8 Kif18A dampens microtubule plus-end dynamics Curr. Biol. 20 2010 374 380
13. M. Wühr, Y. Chen, S. Dumont, A.C. Groen, D.J. Needleman, A. Salic, and T.J. Mitchison Evidence for an upper limit to mitotic spindle length Curr. Biol. 18 2008 1256 1261
14. S. Cai, L.N. Weaver, S.C. Ems-McClung, and C.E. Walczak Kinesin-14 family proteins HSET/XCTK2 control spindle length by cross-linking and sliding microtubules Mol. Biol. Cell 20 2009 1348 1359
15. A.L. Manning, S.F. Bakhoum, S. Maffini, C. Correia-Melo, H. Maiato, and D.A. Compton CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity EMBO J. 29 2010 3531 3543
16. R. Chandra, E.D. Salmon, H.P. Erickson, A. Lockhart, and S.A. Endow Structural and functional domains of the Drosophila ncd microtubule motor protein J. Biol. Chem. 268 1993 9005 9013 (Pubitemid 23118696)
17. S.C. Ems-McClung, Y. Zheng, and C.E. Walczak Importin alpha/beta and Ran-GTP regulate XCTK2 microtubule binding through a bipartite nuclear localization signal Mol. Biol. Cell 15 2004 46 57 (Pubitemid 38044942)
18. J.S. Weinger, M. Qiu, G. Yang, and T.M. Kapoor A nonmotor microtubule binding site in kinesin-5 is required for filament crosslinking and sliding Curr. Biol. 21 2011 154 160
19. C. Tischer, D. Brunner, and M. Dogterom Force- and kinesin-8-dependent effects in the spatial regulation of fission yeast microtubule dynamics Mol. Syst. Biol. 5 2009 250
20. R. Loughlin, R. Heald, and F. Nédélec A computational model predicts Xenopus meiotic spindle organization J. Cell Biol. 191 2010 1239 1249
21. C.N. Newton, M. Wagenbach, Y. Ovechkina, L. Wordeman, and L. Wilson MCAK, a Kin I kinesin, increases the catastrophe frequency of steady-state HeLa cell microtubules in an ATP-dependent manner in vitro FEBS Lett. 572 2004 80 84 (Pubitemid 39092517)
22. C.E. Walczak, T.J. Mitchison, and A. Desai XKCM1: A Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly Cell 84 1996 37 47 (Pubitemid 26031459)
23. M.K. Gardner, D.J. Odde, and K. Bloom Kinesin-8 molecular motors: Putting the brakes on chromosome oscillations Trends Cell Biol. 18 2008 307 310
24. J. Stumpff, Y. Du, C.A. English, Z. Maliga, M. Wagenbach, C.L. Asbury, L. Wordeman, and R. Ohi A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A Mol. Cell 43 2011 764 775
25. X. Su, W. Qui, M.L. Gupta Jr., J.B. Pereira-Leal, S.L. Reck-Peterson, and D. Pellman Mechanisms underlying the dual-mode regulation of microtubule dynamics by Kip3/kinesin-8 Mol. Cell 43 2011 751 763
26. A. Unsworth, H. Masuda, S. Dhut, and T. Toda Fission yeast kinesin-8 Klp5 and Klp6 are interdependent for mitotic nuclear retention and required for proper microtubule dynamics Mol. Biol. Cell 19 2008 5104 5115
27. N.R. Gliksman, S.F. Parsons, and E.D. Salmon Okadaic acid induces interphase to mitotic-like microtubule dynamic instability by inactivating rescue J. Cell Biol. 119 1992 1271 1276