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Volumn 68, Issue , 2013, Pages 38-46
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Hybrid benzofuran-bisindole derivatives: New prototypes with promising anti-hyperlipidemic activities
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Author keywords
Benzofuran bisindole; LCAT activity; Lipid lowering activity; Lipoprotein metabolism; Triton model
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Indexed keywords
(4 CHLOROPHENYL)[5 [DI (1H INDOL 3 YL)METHYL] 7 METHYL BENZOFURAN 2 YL]METHANONE;
(4 CHLOROPHENYL)[5 [DI(1H INDOL 3 YL)METHYL] 7 ETHYLBENZO FURAN 2 YL]METHANONE;
(4 CHLOROPHENYL)[5 [DI(1H INDOL 3 YL)METHYL] 7 ISOPROPYL BENZOFURAN 2 YL]METHANONE;
4 [5 [DI (1H INDOL 3 YL)METHYL] 7 ISOPROPYLBENZOFURAN 2 CARBONYL]BENZONITRILE;
4 [5 [DI (1H INDOL 3 YL)METHYL] 7 METHYLBENZOFURAN 2 CARBONYL]BENZONITRILE;
ANTILIPEMIC AGENT;
BENZOFURAN DERIVATIVE;
CHOLESTEROL;
HIGH DENSITY LIPOPROTEIN;
INDOLE DERIVATIVE;
LOW DENSITY LIPOPROTEIN;
PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE;
PHOSPHOLIPID;
TRIACYLGLYCEROL;
TYLOXAPOL;
UNCLASSIFIED DRUG;
VERY LOW DENSITY LIPOPROTEIN;
[5 [BIS (5 HYDROXY 1H INDOL 3 YL)METHYL] 7 PROPYLBENZO URAN 2 YL](4 METHOXYPHENYL)METHANONE;
[5 [BIS (5 METHOXY 1H INDOL 3 YL)METHYL] 7 CHLOROBENZO FURAN 2 YL](4 METHOXY PHENYL)METHANONE;
[5 [BIS (5 METHOXY 1H INDOL 3 YL)METHYL] 7 ETHYLBENZO FURAN 2 YL](4 METHOXYPHENYL)METHANONE;
[5 [BIS (5 METHOXY 1H INDOL 3 YL)METHYL] 7 PROPYLBENZO FURAN 2 YL](4 METHOXYPHENYL)METHANONE;
[5 [BIS (5 NITRO 1H INDOL 3 YL)METHYL] 7 ETHYLBENZOFURAN 2 YL](4 METHOXYPHENYL)METHANONE;
[5 [BIS (5 NITRO 1H INDOL 3 YL)METHYL] 7 ISOPROPYLBENZO FURAN 2 YL](4 METHOXYPHENYL)METHANONE;
[5 [BIS(5 METHOXY 1H INDOL 3 YL)METHYL] 7 METHYLBENZOFURAN 2 YL](4 METHOXYPHENY)METHANONE;
[5 [BIS(5 METHOXY 1H INDOL 3 YL)METHYL] 7 TERT BUTYLBENZO FURAN 2 YL](4 METHOXY PHENYL)METHANONE;
[5 [DI (1H INDOL 3 YL)METHYL] 7 ETHYLBENZOFURAN 2 YL](4 METHOXYPHENYL)METHANONE;
[5 [DI (1H INDOL 3 YL)METHYL] 7 METHYLBENZOFURAN 2 YL](4 METHOXYPHENYL)METHANONE;
[5 [DI (1H INDOL 3 YL)METHYL] 7 METHYLBENZOFURAN 2 YL](4 TOLYL)METHANONE;
[5 [DI(1H INDOL 3 YL)METHYL] 7 ISOPROPYLBENZOFURAN 2 YL](4 METHOXYPHENYL)METHANONE;
[7 TERT BUTYL 5 [DI (1H INDOL 3 YL)METHYL]BENZOFURAN 2 YL](4 CHLOROPHENYL)METHANONE;
[7 TERT BUTYL 5 [DI (1H INDOL 3 YL)METHYL]BENZOFURAN 2 YL](4 METHOXYPHENYL)METHANONE;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANTIOXIDANT ACTIVITY;
ARTICLE;
CHOLESTEROL BLOOD LEVEL;
CONTROLLED STUDY;
DRUG SYNTHESIS;
ENZYME ACTIVITY;
HYPERLIPIDEMIA;
IN VITRO STUDY;
IN VIVO STUDY;
LIPOLYSIS;
LIPOPROTEIN METABOLISM;
MALE;
NONHUMAN;
RAT;
BENZOFURAN-BISINDOLE;
LCAT ACTIVITY;
LIPID LOWERING ACTIVITY;
LIPOPROTEIN METABOLISM;
TRITON MODEL;
ANIMALS;
ANTIOXIDANTS;
BENZOFURANS;
CHOLESTEROL;
ENZYME ACTIVATION;
HYPOLIPIDEMIC AGENTS;
INDOLES;
LIPOLYSIS;
MALE;
MOLECULAR STRUCTURE;
PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE;
PHOSPHOLIPIDS;
RATS;
TRIGLYCERIDES;
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EID: 84881531754
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2013.07.009 Document Type: Article |
Times cited : (53)
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References (32)
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