Enhancement of fluid filtration across tumor vessels: Implication for delivery of macromolecules

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 6, 1999, Pages 3137-3142

  Netti, Paolo A ^a   Hamberg, Leena M ^a   Babich, John W ^a   Kierstead, Diane ^a   Graham, Wendy ^a   Hunter, George J ^a   Wolf, Gerald L ^a   Fischman, Alan ^a   Boucher, Yves ^a   Jain, Rakesh K ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ANTIBODY; HYDRAZINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; CANCER THERAPY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG UPTAKE; ENDOTHELIUM; EXTRAVASATION; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; MACROMOLECULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOLID TUMOR; TISSUE PRESSURE; TUMOR BLOOD FLOW; TUMOR VASCULARIZATION;

EID: 13044292648     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.6.3137     Document Type: Article

References (51)

1. Jain, R. K. (1997) Microcirculation 4, 1-23.
2. Jain, R. K. (1994) Sci. Am. 271, 58-65.
3. Sands, H. (1992) J. Nucl. Med. 33, 29-32.
4. Hall, S. S. (1995) Science 270, 915-916.
5. Jain, R. K. (1996) Science 271, 1079-1080.
6. Bobo, H. R., Laske, D. W., Akbasac, A., Morrison, P. F., Dedrick, R. L. & Oldfield, E. H. (1994) Proc. Natl. Acad. Sci. USA 91, 2076-2080.
7. Langer, R. (1998) Nature (London) 392, 5-10.
8. Jain, R. K. (1998) Nat. Med. 4, 655-657.
9. Rippe, B. & Haraldsson, B. (1994) Phys. Rev. 74, 163-218.
10. Flessner, M. F. & Dedrick, R. L. (1994) Cancer Res. 54, 4376-4384.
11. Boucher, Y., Baxter, L. T. & Jain, R. K. (1990) Cancer Res. 50, 4478-4484.
12. Young, J. S., Lumsden, C. E. & Stalker, A. L. (1950) J. Pathol. Bacteriol. 62, 313-333.
13. Gullino, P. M., Clark, S. H. & Grantham, F. H. (1964) Cancer Res. 24, 780-797.
14. Jain, R. K. & Baxter, L. T. (1988) Cancer Res. 48, 7022-7032.
15. Bakir, M. A., Eccles, S. A., Babich, J. W., Aftab, N., Styles, J. M., Dean, C. J. & Ott, R. J. (1992) J. Nucl. Med. 33, 2154-2160.
16. Boucher, Y., Kirkwood, J., Opacic, D., DeSantis, M. & Jain, R. K. (1991) Cancer Res. 51, 6691-6694.
17. Boucher, Y. & Jain, R. K. (1992) Cancer Res. 52, 5110-5114.
18. Less, R. J., Posner, M. C., Boucher, Y., Borochovitz, D., Wolmark, N. & Jain, R. K. (1992) Cancer Res. 52, 6371-6374.
19. Netti, P. A., Roberge, S., Boucher, Y., Baxter, L. T. & Jain, R. K. (1996) Microvascular Res. 52, 27-46.
20. Netti, P. A., Baxter, L. T., Boucher, Y., Skalak, R. & Jain, R. K. (1995) Cancer Res. 55, 5451-5458.
21. Hori, K., Suzuki, M., Abe, I., Saito, S. & Sato, H. (1985) J. Natl. Cancer Inst. 74, 453-459.
22. Zlotecki, R. A., Boucher, Y., Lee, I., Baxter, L. T. & Jain, R. K. (1993) Cancer Res. 53, 2466-2468.
23. Jain, R. K. (1988) Cancer Res. 48, 2641-2658.
24. Krylova, N. V. (1969) Bibl. Anat. 10, 301-303.
25. Zlotecki, R. A., Baxter, L. T., Boucher, Y. & Jain, R. K. (1995) Microvasc. Res. 50, 429-443.
26. Hori, K., Suzuki, M., Saito, S., Tanda, S., Zhang, Q.-H. & Li, H.-C. (1994) Microvasc. Res. 48, 246-256.
27. Kristjansen, P. E. G., Roberge, S., Lee, I. & Jain, R. K. (1994) Microvasc. Res. 48, 389-402.
28. Leunig, M., Yuan, F., Menger, D. M., Boucher, Y., Goetz, A. F., Messmer, K. & Jain, R. K. (1992) Cancer Res. 52, 6553-6560.
29. Yuan, F., Dellian, M., Fukumura, D., Leunig, M., Berk, D. A., Torchilin, V. P. & Jain, R. K. (1995) Cancer Res. 55, 3752-3756.
30. Yuan, F., Leunig, M., Berk, D. A. & Jain, R. K. (1993) Microvasc. Res. 45, 269-289.
31. Milenic, D. E., Yokota, T., Filpula, D. R., Finkelman, M. A. J., Dodd, S. W., Wood, J. F., Whitlow, M., Snoy, P. & Schlom, J. (1991) Cancer Res. 51, 6363-6371.
32. Abrams, M. J., Juweid, M., tenKate, C. I., Schwartz, D. A., Hauser, M. M., Gaul, F. E., Fuccello, A. J., Rubin, R. H., Strauss, H. W. & Fischman, A. J. (1990) J. Nucl. Med. 31, 2022-2028.
33. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254.
34. Fraker, P. J. & Speck, J. C. (1978) Biochem. Biophys. Res. Commun. 80, 849-853.
35. Intaglietta, M., Pawula, R. F. & Tompkins, W. R. (1970) Microvasc. Res. 2, 212-220.
36. Hori, K., Zhang, Q., Saito, S., Tanda, S., Li, H. & Suzuki, M. (1993) Cancer Res. 53, 5528-5534.
37. Less, J. R., Skalak, T. C., Sevick, E. M. & Jain, R. K. (1991) Cancer Res. 51, 265-273.
38. Baxter, L. T., Zhu, H., Mackensen, D. G. & Jain, R. K. (1994) Cancer Res. 54, 1517-1528.
39. Hori, K., Suzuki, M., Tanda, S., Saito, S. & Zhang, Q. H. (1993) Int. J. Oncol. 2, 289-296.
40. Jain, R. K. (1987) Cancer Metastasis Rev. 6, 559-593.
41. Fung, Y. C. (1990) in Biomechanics: Motion, Flow, Stress and Growth (Springer, New York).
42. Abe, I., Hori, K., Saito, S., Tanda, S., Li, Y. & Suzuki, M. (1988) Jpn. J. Cancer Res. 79, 874-879.
43. Elizondo, F. G. J. & Sung, C. (1996) Cancer Chemother. Pharmacol. 39, 113-121.
44. Li, C. J., Miyamoto, Y., Kojima, Y. & Maeda, H. (1993) Br. J. Cancer 67, 975-980.
45. Noguchi, A., Takahashi, T., Yamaguchi, T., Kitamura, K., Noguchi, A., Tsumuri, H., Takashina, K. & Maeda, H. (1992) Jpn. J. Cancer Res. 83, 240-243.
46. Takeda, A., Kikuki, T., Ozaki, M., Ariga, T., Nagashima, T., Isono, K. & Miyoski, T. (1991) Nippon Ega Cakkai Zasshi 92, 475.
47. Hansen, T. N., Le Blanc, A. L. & Gest, A. L. (1985) J. Appl. Physiol. 58, 812-818.
48. Roy, B. J., Pitts, V. H. & Townsley, M. I. (1996) Am. J. Physiol. 271, H222-H227.
49. Suzuki, M., Hori, K., Abe, I., Saito, S. & Sato, H. (1981) J. Natl. Canc. Inst. 67, 663-669.
50. Reed, R. K., Rubin, K., Wiig, H. & Rodt, S. A. (1992) Circulation Res. 71, 978-983.
51. Znati, C. A., Rosenstein, M., Boucher, Y., Epperly, M. W., Bloomer, W. D. & Jain, R. K. (1996) Cancer Res. 56, 964-968.