The role of positive charges on G-quadruplex binding small molecules: Learning from bisaryldiketene derivatives

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 11, 2013, Pages 5006-5013

  Chen, Shuo Bin ^a   Shi, Qiu Xia ^a   Peng, Dan ^a   Huang, Si Yuan ^a   Ou, Tian Miao ^a   Li, Ding ^a   Tan, Jia Heng ^a   Gu, Lian Quan ^a   Huang, Zhi Shu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

G quadruplex Bisaryldiketene derivative Positive charge Biophysical study Molecular modeling

Indexed keywords

BISARYLDIKETENE DERIVATIVE; GUANINE QUADRUPLEX; KETENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CIRCULAR DICHROISM; CONTROLLED STUDY; DNA BINDING; ELECTRIC POTENTIAL; ISOTHERMAL TITRATION CALORIMETRY; LIGAND BINDING; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POSITIVE CHARGE; PRIORITY JOURNAL; SURFACE CHARGE; ULTRAVIOLET SPECTROSCOPY;

BIOPHYSICAL STUDY; BISARYLDIKETENE DERIVATIVE; G-QUADRUPLEX; MOLECULAR MODELING; POSITIVE CHARGE;

CALORIMETRY; CIRCULAR DICHROISM; DNA; G-QUADRUPLEXES; KINETICS; LACTONES; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; SMALL MOLECULE LIBRARIES; SPECTROPHOTOMETRY, ULTRAVIOLET; THERMODYNAMICS;

EID: 84881526464     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.07.012     Document Type: Article

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