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Angewandte Chemie - International Edition

Volumn 40, Issue 24, 2001, Pages 4749-4751

Recognition and stabilization of quadruplex DNA by a potent new telomerase inhibitor: NMR studies of the 2:1 complex of a pentacyclic methylacridinium cation with d(TTAGGGT)4

(4) Gavathiotis, Evripidis a Heald, Robert A a Stevens, Malcolm F G a Searle, Mark S a

a UNIVERSITY OF NOTTINGHAM (United Kingdom)

Author keywords

DNA recognition; G quadruplex; NMR spectroscopy; Telomerase

Indexed keywords

COMPUTER SIMULATION; ENZYME INHIBITION; ENZYMES; NUCLEAR MAGNETIC RESONANCE; POSITIVE IONS; POTASSIUM;

LOW-ENERGY STRUCTURES;

DNA;

ACRIDINE DERIVATIVE; DNA; GUANINE DERIVATIVE; METHYLACRIDINIUM; TELOMERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; DNA DETERMINATION; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; MITOSIS INHIBITION; NUCLEAR MAGNETIC RESONANCE; TANDEM REPEAT; TELOMERE;

EID: 0035905416 PISSN: 14337851 EISSN: None Source Type: Journal
DOI: 10.1002/1521-3773(20011217)40:24<4749::AID-ANIE4749>3.0.CO;2-I Document Type: Article

Times cited : (81)

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