Systematic evaluation of biocompatibility of magnetic Fe3O 4 nanoparticles with six different mammalian cell lines

Journal of Nanoparticle Research

Volumn 13, Issue 1, 2011, Pages 199-212

  Liu, Yingxun ^a   Chen, Zhongping ^a   Wang, Jinke ^a  

^a SOUTHEAST UNIVERSITY   (China)

Author keywords

Apoptosis; Biocompatibility; Health and safety; Magnetic nanoparticles; Oxidative stress; Uptake

Indexed keywords

APOPTOSIS; CELL CYCLE; CELL LABELING; CELL VIABILITY; CLINICAL APPLICATION; HEALTH AND SAFETY; HEPG2 CELLS; HUMAN STUDY; IMAGING AGENT; INTRAVASCULAR; IRON LOADING; MAGNETIC NANOPARTICLES; MAMMALIAN CELL LINES; SUPER OXIDE DISMUTASE; SYSTEMATIC EVALUATION; UPTAKE; XANTHINE OXIDASE;

BIOCOMPATIBILITY; CELL CULTURE; CELL DEATH; MAMMALS; NANOPARTICLES; OXIDATIVE STRESS; OXYGEN; STRESS ANALYSIS;

NANOMAGNETICS;

MAGNETITE; MALONALDEHYDE; NANOPARTICLE; SUCCIMER; SUPEROXIDE DISMUTASE; XANTHINE OXIDASE;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL LABELING; CELL LINE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 79551593302     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-010-0019-y     Document Type: Article

References (59)

1. PE Adams 1995 Determining iron content in foods by spectrophotometry J Chem Educ 72 7 649 665 1:CAS:528:DyaK2MXnt1arsLs%3D 10.1021/ed072p649
2. M Auffan L Decome J Rose T Orsiere M De Meo V Briois C Chaneac L Olivi JL Berge-Lefranc A Botta MR Wiesner JY Bottero 2006 In vitro interactions between DMSA-coated maghemite nanoparticles and human fibroblasts: a physicochemical and cyto-genotoxical study Environ Sci Technol 40 4367 4373 1:CAS:528: DC%2BD28Xkslymtrs%3D 10.1021/es060691k
3. BR Bacon DD Stark CH Park S Saini EV Groman PF Hahn CC Compton JT Ferrucci 1987 Ferrite particles: a new magnetic resonance imaging contrast agent. Lack of acute or chronic hepatotoxicity after intravenous administration J Lab Clin Med 110 164 171 1:CAS:528:DyaL2sXltFWrt70%3D
4. CC Berry S Wells S Charles AS Curtis 2003 Dextran and albumin derivatised iron oxide nanoparticles: influence on fibroblasts in vitro Biomaterials 24 4551 4557 1:CAS:528:DC%2BD3sXmvVanu7g%3D 10.1016/S0142-9612(03)00237-0
5. CC Berry S Wells S Charles G Aitchison ASG Curds 2004 Cell response to dextran-derivatised iron oxide nanoparticles post internalisation Biomaterials 25 23 5405 5413 1:CAS:528:DC%2BD2cXjslemt7c%3D 10.1016/j.biomaterials.2003.12. 046
6. WF Beyer I Fridovich 1991 Phosphate, not superoxide dismutase, facilitates electron transfer from ferrous salts to cytochrome c Arch Biochem Biophys 285 60 63 1:CAS:528:DyaK3MXnslegtg%3D%3D 10.1016/0003-9861(91)90328-G
7. R Brayner 2008 The toxicological impact of nanoparticles Nano Today 3 48 55 10.1016/S1748-0132(08)70015-X
8. JW Bulte T Douglas B Witwer SC Zhang E Strable BK Lewis H Zywicke B Miller P van Gelderen BM Moskowitz ID Duncan JA Frank 2001 Magnetodendrimers allow endosomal magnetic labeling and in vivo tracking of stem cells Nat Biotechnol 19 1141 1147 1:CAS:528:DC%2BD3MXptV2rt7Y%3D 10.1038/nbt1201-1141
9. ZP Chen RZ Xu Y Zhang N Gu 2005 Effects of proteins from culture medium on surface property of silanes-functionalized magnetic nanoparticles Nanoscale Res Lett 40 2 83 91 1:CAS:528:DC%2BD28XhtlWgur8%3D
10. ZP Chen Y Zhang S Zhang JG Xia JW Liu K Xu N Gu 2008 Preparation and characterization of water-soluble monodisperse magnetic iron oxide nanoparticles via surface double-exchange with DMSA Colloids Surf A Physicochem Eng Asp 316 210 216 1:CAS:528:DC%2BD1cXhsVCqtLk%3D 10.1016/j.colsurfa.2007.09.017
11. 4 nanoparticles and their biomedical applications Biomaterials 26 7 729 738 1:CAS:528:DC%2BD2cXnt1Gqurc%3D 10.1016/j.biomaterials.2004.03.016
12. E Duguet S Vasseur S Mornet JM Devoisselle 2006 Magnetic nanoparticles and their applications in medicine Nanomedicine 1 2 157 168 1:CAS:528: DC%2BD28XpsFKis7Y%3D 10.2217/17435889.1.2.157
13. MD Dunning A Lakatos L Loizou M Kettunen C Ffrench-Constant KM Brindle RJ Franklin 2004 Superparamagnetic iron oxide-labeled Schwann cells and olfactory ensheathing cells can be traced in vivo by magnetic resonance imaging and retain functional properties after transplantation into the CNS J Neurosci 24 44 9799 9810 1:CAS:528:DC%2BD2cXhtVWhtrfK 10.1523/JNEUROSCI.3126-04.2004
14. E Farrell P Wielopolski P Pavljasevic N Kops H Weinans MR Bernsen GJ van Osch 2009 Cell labelling with superparamagnetic iron oxide has no effect on chondrocyte behaviour Osteoarthritis Cartilage 17 7 961 967 1:STN:280: DC%2BD1MzpslSmsw%3D%3D 10.1016/j.joca.2008.11.016
15. WW Fish 1988 Rapid colorimetric micromethod for the quantitation of complexed iron in biological samples Methods Enzymol 158 357 364 1:CAS:528:DyaL1cXktlCks7Y%3D 10.1016/0076-6879(88)58067-9
16. A Gajdosíková A Gajdosík M Koneracká V Závisová S Stvrtina V Krchnárová P Kopcanský N Tomasovicová S Stolc M Timko 2006 Acute toxicity of magnetic nanoparticles in mice Neuro Endocrinol Lett 27 Suppl 2 96 99
17. T Green-Sadan Y Kuttner T Lublin-Tennenbaum N Kinor Y Boguslavsky S Margel G Yadid 2005 Glial cell line-derived neurotrophic factor-conjugated nanoparticles suppress acquisition of cocaine self-administration in rats Exp Neurol 194 1 97 105 1:CAS:528:DC%2BD2MXkt1Gis7s%3D 10.1016/j.expneurol.2005.01. 020
18. AK Gupta AS Curtis 2004 Surface modified superparamagnetic nanoparticles for drug delivery: interaction studies with human fibroblasts in culture J Mater Sci Mater Med 15 4 493 496 1:CAS:528:DC%2BD2cXisVWlsr8%3D 10.1023/B:JMSM. 0000021126.32934.20
19. UO Häfeli GJ Pauer 1999 In vitro and in vivo toxicity of magnetic microspheres J Magn Magn Mater 194 76 82 10.1016/S0304-8853(98)00560-5
20. UO Häfeli JS Riffle L Harris-Shekhawat A Carmichael-Baranauskas F Mark JP Dailey D Bardenstein 2009 Cell uptake and in vitro toxicity of magnetic nanoparticles suitable for drug delivery Mol Pharm 6 5 1417 1428 10.1021/mp900083m
21. MG Harisinghani J Barentsz PF Hahn WM Deserno S Tabatabaei CH van de Kaa J de la Rosette R Weissleder 2003 Noninvasive detection of clinically occult lymph-node metastases in prostate cancer N Engl J Med 348 2491 2499 10.1056/NEJMoa022749
22. HC Huang PY Chang K Chang CY Chen CW Lin JH Chen CY Mou ZF Chang FH Chang 2009 Formulation of novel lipid-coated magnetic nanoparticles as the probe for in vivo imaging J Biomed Sci 16 1 86 10.1186/1423-0127-16-86
23. SM Hussain KL Hess JM Gearhart KT Geiss JJ Schlager 2005 In vitro toxicity of nanoparticles in BRL 3A rat liver cells Toxicol In Vitro 19 7 975 983 1:CAS:528:DC%2BD2MXhtFOhtLnE 10.1016/j.tiv.2005.06.034
24. A Ito M Shinkai H Honda T Kobayashi 2005 Medical application of functionalized magnetic nanoparticles J Biosci Bioeng 100 1 1 11 1:CAS:528:DC%2BD2MXhtVaqu7vM 10.1263/jbb.100.1
25. TK Jain MA Morales SK Sahoo DL Leslie-Pelecky V Labhasetwar 2005 Iron oxide nanoparticles for sustained delivery of anticancer agents Mol Pharm 2 194 205 1:CAS:528:DC%2BD2MXjtl2jt7Y%3D 10.1021/mp0500014
26. TK Jain MK Reddy MA Morales DL Leslie-Pelecky V Labhasetwar 2008 Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats Mol Pharm 5 2 316 327 1:CAS:528:DC%2BD1cXhtVyitbg%3D 10.1021/mp7001285
27. HA Jeng J Swanson 2006 Toxicity of metal oxide nanoparticles in mammalian cells J Environ Sci Health A Tox Hazard Subst Environ Eng 41 12 2699 2711 1:CAS:528:DC%2BD28Xht1yksbnO
28. SH Ju GJ Teng Y Zhang M Ma F Chen YY Ni 2006 In vitro labeling and MRI of mesenchymal stem cells from human umbilical cord blood Magn Reson Imaging 24 5 611 617 10.1016/j.mri.2005.12.017
29. VS Kalambur EK Longmire JC Bischof 2007 Cellular level loading and heating of superparamagnetic iron oxide nanoparticles Langmuir 23 24 12329 12336 1:CAS:528:DC%2BD2sXht1WmtLrL 10.1021/la701100r
30. JS Kim TJ Yoon KN Yu BG Kim SJ Park HW Kim KH Lee SB Park JK Lee MH Cho 2006 Toxicity and tissue distribution of magnetic nanoparticles in mice Toxicol Sci 89 1 338 347 1:CAS:528:DC%2BD2MXhtlagtLfI 10.1093/toxsci/kfj027
31. LM Lacava VAP Garcia S Kückelhaus RB Azevedo N Sadeghiani N Buske PC Morais ZGM Lacava 2004 Long-term retention of dextran-coated magnetite nanoparticles in the liver and spleen J Magn Magn Mater 272 2434 2435 10.1016/j.jmmm.2003.12.852
32. 4 in anticancer drug carriers with target-orientation and sustained-release properties Biomed Mater 2 2 132 134 1:CAS:528: DC%2BD2sXnvVamu7Y%3D 10.1088/1748-6041/2/2/011
33. S Liu L Long Z Yuan L Yin R Liu 2009 Effect and intracellular uptake of pure magnetic Fe3O4 nanoparticles in the cells and organs of lung and liver Chinese Med J 122 15 1821 1825 1:CAS:528:DC%2BD1MXhtV2qur%2FE
34. DJ Maxwell J Bonde DA Hess SA Hohm R Lahey P Zhou MH Creer D Piwnica-Worms JA Nolta 2008 Fluorophore-conjugated iron oxide nanoparticle labeling and analysis of engrafting human hematopoietic stem cells Stem Cells 26 2 517 524 1:CAS:528:DC%2BD1cXjt1Wls7w%3D 10.1634/stemcells.2007-0016
35. K Muller J Skeppera M Posfaib R Trivedi S Howarth C Corot E Lancelot P Thompson A Brown J Gillard 2007 Effect of ultrasmall superparamagnetic iron oxide nanoparticles (Ferumoxtran-10) on human monocyte-macrophages in vitro Biomaterials 28 9 1629 1642 10.1016/j.biomaterials.2006.12.003
36. C Nebot M Moutet P Huet JZ Xu JC Yadan J Chaudiere 1993 Spectrophotometric assay of superoxide dismutase activity based on the activated autoxidation of a tetracyclic catechol Anal Biochem 214 442 451 1:CAS:528:DyaK2cXnt1Shsw%3D%3D 10.1006/abio.1993.1521
37. QA Pankhurst J Connolly SK Jones J Dobson 2003 Applications of magnetic nanoparticles in biomedicine J Phys D Appl Phys 36 13 167 181 10.1088/0022-3727/36/13/201
38. R Pieters DR Huismans A Leyva AJP Veerman 1989 Comparison of the rapid automated MTT-assay with a dye exclusion assay for chemosensitivity testing in childhood leukaemia Br J Cancer 59 217 220 1:STN:280:DyaL1M7psVSmsQ%3D%3D 10.1038/bjc.1989.44
39. TR Pisanic JD Blackwell VI Shubayev RR Finones S Jin 2007 Nanotoxicity of iron oxide nanoparticle internalization in growing neurons Biomaterials 28 16 2572 2581 1:CAS:528:DC%2BD2sXis1CrsLk%3D 10.1016/j.biomaterials.2007.01.043
40. AM Rad B Janic ASM Iskander H Soltanian-Zadeh AS Arbab 2007 Measurement of quantity of iron in magnetically labeled cells: comparison among different UV/VIS spectrometric methods Biotechniques 43 627 636 1:CAS:528: DC%2BD2sXhtl2ntbnE 10.2144/000112599
41. C Rivière FP Boudghène F Gazeau J Roger JN Pons JP Laissy E Allaire JB Michel D Letourneur JF Deux 2005 Iron oxide nanoparticle-labeled rat smooth muscle cells: cardiac MR imaging for cell graft monitoring and quantitation Radiology 235 959 967 10.1148/radiol.2353032057
42. N Sadeghiani LS Barbosa LP Silva RB Azevedo PC Morais ZGM Lacava 2005 Genotoxicity and inflammatory investigation in mice treated with magnetite nanoparticles surface coated with polyaspartic acid J Magn Magn Mater 289 466 468 1:CAS:528:DC%2BD2MXitlSmurk%3D 10.1016/j.jmmm.2004.11.131
43. S Schwarz F Fernandes L Sanroman M Hodenius C Lang U Himmelreich T Schmitz-Rode D Schueler M Hoehn M Zenke T Hieronymus 2009 Synthetic and biogenic magnetite nanoparticles for tracking of stem cells and dendritic cells J Magn Magn Mater 321 1533 1538 1:CAS:528:DC%2BD1MXks12iur8%3D 10.1016/j.jmmm.2009.02. 081
44. SY Shaw EC Westly MJ Pittet A Subramanian SL Schreiber R Weissleder 2008 Perturbational profiling of nanomaterial biologic activity Proc Natl Acad Sci USA 105 21 7387 7392 1:CAS:528:DC%2BD1cXmvFOlt7k%3D 10.1073/pnas.0802878105
45. VI Shubayev TR Pisanic S Jin 2009 Magnetic nanoparticles for theragnostics Adv Drug Deliv Rev 6 467 477 10.1016/j.addr.2009.03.007
46. M Song WK Moon Y Kim D Lim IC Song BW Yoon 2007 Labeling efficacy of superparamagnetic iron oxide nanoparticles to human neural stem cells: comparison of ferumoxides, monocrystalline iron oxide, cross-linked iron oxide (CLIO)-NH2 and tat-CLIO Korean J Radiol 8 365 371 10.3348/kjr.2007.8.5.365
47. A Stroh C Zimmer C Gutzeit M Jakstadt F Marschinke T Jung H Pilgrimm T Grune 2004 Iron oxide particles for molecular magnetic resonance imaging cause transient oxidative stress in rat macrophages Free Radic Biol Med 36 976 984 1:CAS:528:DC%2BD2cXis1Wnsbw%3D 10.1016/j.freeradbiomed.2004.01.016
48. Tiefenauer LX (2007) Chapter 29: Magnetic nanoparticles as contrast agents for medical diagnosis. In: Vo-Dinh T (ed) Nanotechnology in biology and medicine: methods, devices, and applications. CRC Press, Boca Raton, pp 1-20
49. BA Tucker M Rahimtula KM Mearow 2005 A procedure for selecting and culturing subpopulations of neurons from rat dorsal root ganglia using magnetic beads Brain Res Brain Res Protoc 16 1-3 50 57 10.1016/j.brainresprot.2005.10.004
50. M Valko CJ Rhodes J Moncol M Izakovic M Mazur 2006 Free radicals, metals and antioxidants in oxidative stress-induced cancer Chem Biol Interact 160 1 40 1:CAS:528:DC%2BD28XhsF2hsrY%3D 10.1016/j.cbi.2005.12.009
51. Weber C, Falkenhagen D (1997) Specific blood purification by means of antibody-conjugated magnetic microspheres. In: Hafeli U, Shutt W, Teller J, Zborowski M (eds) Scientific and clinical applications of magnetic carriers. Plenum Press, New York, pp 371-378
52. R Weissleder DD Stark BL Engelstad BR Bacon CC Compton DL White P Jacobs J Lewis 1989 Superparamagnetic iron oxide: pharmacokinetics and toxicity Am J Roentgenol 152 167 173 1:STN:280:DyaL1M%2FnsVCruw%3D%3D
53. R Weissleder A Moore U Mahmood R Bhorade H Benveniste EA Chiocca JP Basilion 2000 In vivo magnetic resonance imaging of transgene expression Nat Med 6 3 351 355 1:CAS:528:DC%2BD3cXhslygs7c%3D 10.1038/73219
54. LJ Wesselius WL Williams K Bailey S Vamos AR O'Brien-Ladner T Wiegmann 1999 Iron uptake promotes hyperoxic injury to alveolar macrophages Am J Respir Crit Care Med 159 1 100 106 1:STN:280:DyaK1M%2FptFygug%3D%3D
55. C Wilhelm F Gazeau 2008 Universal cell labelling with anionic magnetic nanoparticles Biomaterials 29 3161 3174 1:CAS:528:DC%2BD1cXmt1ejtL0%3D 10.1016/j.biomaterials.2008.04.016
56. C Wilhelm F Gazeau JC Bacri 2002 Magnetophoresis and ferromagnetic resonance of magnetically labeled cells Eur Biophys J 31 2 118 125 1:CAS:528:DC%2BD38XjtlKqsbs%3D 10.1007/s00249-001-0200-4
57. C Wilhelm F Gazeau J Roger JN Pons JC Bacri 2002 Interaction of anionic superparamagnetic nanoparticles with cells: kinetic analyses of membrane adsorption and subsequent internalization Langmuir 18 21 8148 8155 1:CAS:528:DC%2BD38XmvVGmsLs%3D 10.1021/la0257337
58. C Wilhelm C Billotey J Roger JN Pons JC Bacri F Gazeau 2003 Intracellular uptake of anionic superparamagnetic nanoparticles as a function of their surface coating Biomaterials 24 1001 1011 1:CAS:528:DC%2BD38Xps1Omsro%3D 10.1016/S0142-9612(02)00440-4
59. Z Yu W Xiaoliang W Xuman X Hong G Hongchen 2008 Acute toxicity and irritation of water-based dextran-coated magnetic fluid injected in mice J Biomed Mater Res 85 3 582 587 10.1002/jbm.a.31189