Spinocerebellar ataxia-13 Kv3.3 potassium channels: Arginine-to-histidine mutations affect both functional and protein expression on the cell surface

Biochemical Journal

Volumn 454, Issue 2, 2013, Pages 259-265

  Zhao, Jian ^a   Zhu, Jing ^a   Thornhill, William B ^a  

^a FORDHAM UNIVERSITY   (United States)

Author keywords

Potassium channel; Protein expression; Protein stability; Side chain; Spinocerebellar ataxia type 13 (SCA13); Trafficking

Indexed keywords

ALANINE; ARGININE; HISTIDINE; MUTANT PROTEIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL KV3.3; PROTEASOME; TRIMETHYLAMINE OXIDE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BIOTINYLATION; CELL SURFACE; CONTROLLED STUDY; GENE MUTATION; GENETIC TRANSFECTION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; OOCYTE; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN STABILITY; SPINOCEREBELLAR ATAXIA TYPE 13; SPINOCEREBELLAR DEGENERATION; XENOPUS;

AMINO ACID SUBSTITUTION; ANIMALS; CELL MEMBRANE; CHO CELLS; CRICETINAE; CRICETULUS; GENE EXPRESSION REGULATION; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; OXIDANTS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEASOME INHIBITORS; PROTEIN ISOFORMS; PROTEIN STABILITY; PROTEIN SYNTHESIS INHIBITORS; RECOMBINANT PROTEINS; SHAW POTASSIUM CHANNELS; SPINOCEREBELLAR ATAXIAS; SURFACE PROPERTIES;

EID: 84881485140     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20130034     Document Type: Article

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