Correlation between topographic N400 anomalies and reduced cerebral blood flow in the anterior temporal lobes of patients with dementia

Journal of Alzheimer's Disease

Volumn 36, Issue 4, 2013, Pages 711-731

  Grieder, Matthias ^a   Crinelli, Raffaella M ^b   Jann, Kay ^a,c   Federspiel, Andrea ^a   Wirth, Miranka ^d   Koenig, Thomas ^a   Stein, Maria ^a   Wahlund, Lars Olof ^b   Dierks, Thomas ^a  

^a University Hospital of Psychiatry   (Switzerland)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; cerebral blood flow; event related potential; magnetic resonance imaging; N400; semantic dementia; semantic memory; volumetry

Indexed keywords

AGED; ALZHEIMER DISEASE; ARTICLE; AUTOMATION; BRAIN BLOOD FLOW; BRAIN MAPPING; ELECTROENCEPHALOGRAM; EVENT RELATED POTENTIAL; HUMAN; INCIDENTAL FINDING; MENTAL DETERIORATION; MINI MENTAL STATE EXAMINATION; N400 TOPOGRAPHY; NEUROLOGIC EXAMINATION; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SEMANTIC DEMENTIA; SEMANTIC MEMORY; TEMPORAL LOBE;

AGED; CEREBROVASCULAR CIRCULATION; DEMENTIA; ELECTROENCEPHALOGRAPHY; EVOKED POTENTIALS; FEMALE; HUMANS; MALE; MIDDLE AGED; TEMPORAL LOBE;

EID: 84881446380     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-121690     Document Type: Article

References (82)

1. Castellani RJ, Rolston RK, Smith MA (2010) Alzheimer disease. Dis Mon 56, 484-546.
2. Lopes MA, Hototian SR, Bustamante SE, Azevedo D, Tatsch M, Bazzarella MC, Litvoc J, BottinoCM(2007) Prevalence of cognitive and functional impairment in a community sample in Ribeirao Preto, Brazil. Int J Geriatr Psychiatry 22, 770-776.
3. Fratiglioni L, De Ronchi D, Aguero-Torres H (1999) Worldwide prevalence and incidence of dementia. Drugs Aging 15, 365-375.
4. Brugger P, Monsch AU, Salmon DP, Butters N (1996) Random number generation in dementia of the Alzheimer type: A test of frontal executive functions. Neuropsychologia 34, 97-103.
5. Sebastian GasconMV, Hernandez-GilL(2010)Acomparison of memory and executive functions in Alzheimer disease and the frontal variant of frontotemporal dementia. Psicothema 22, 424-429.
6. Nyatsanza S, Shetty T, Gregory C, Lough S, Dawson K, Hodges JR (2003) A study of stereotypic behaviours in Alzheimer's disease and frontal and temporal variant frontotemporal dementia. J Neurol Neurosurg Psychiatry 74, 1398-1402.
7. Hodges JR (2001) Frontotemporal dementia (Pick's disease): Clinical features and assessment. Neurology 56, S6-10.
8. Snowden JS, Neary D, Mann DM, Goulding PJ, Testa HJ (1992) Progressive language disorder due to lobar atrophy. Ann Neurol 31, 174-183.
9. Gorno-Tempini ML, Hillis AE, Weintraub S, Kertesz A, Mendez M, Cappa SF, Ogar JM, Rohrer JD, Black S, Boeve BF, Manes F, Dronkers NF, Vandenberghe R, Rascovsky K, Patterson K, Miller BL, Knopman DS, Hodges JR, Mesulam MM, Grossman M (2011) Classification of primary progressive aphasia and its variants. Neurology 76, 1006-1014.
10. Jack CR, Albert MS, Knopman DS, McKhann GM, Sperling RA, Carrillo MC, Thies B, Phelps CH (2011) Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 257-262.
11. Perrin RJ, FaganAM, HoltzmanDM(2009) Multimodal techniques for diagnosis and prognosis of Alzheimer's disease. Nature 461, 916-922.
12. Neary D, Snowden JS, Gustafson L, Passant U, Stuss D, Black S, Freedman M, Kertesz A, Robert PH, Albert M, Boone K, Miller BL, Cummings J, Benson DF (1998) Frontotemporal lobar degeneration: A consensus on clinical diagnostic criteria. Neurology 51, 1546-1554.
13. Pengas G, Patterson K, Arnold RJ, Bird CM, Burgess N, Nestor PJ (2010) Lost and found: Bespoke memory testing for Alzheimer's disease and semantic dementia. J Alzheimers Dis 21, 1347-1365.
14. Austin BP, Nair VA, Meier TB, Xu G, Rowley HA, Carlsson CM, Johnson SC, Prabhakaran V (2011) Effects of hypoperfusion in Alzheimer's disease. J Alzheimers Dis 26(Suppl 3), 123-133.
15. Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM, Iwatsubo T, Jack CR Jr, Kaye J, Montine TJ, Park DC, Reiman EM, Rowe CC, Siemers E, Stern Y, Yaffe K, Carrillo MC, Thies B, Morrison-Bogorad M, Wagster MV, Phelps CH (2011) Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 280-292.
16. Blackwell AD, Sahakian BJ, Vesey R, Semple JM, Robbins TW, Hodges JR (2004) Detecting dementia: Novel neuropsychological markers of preclinical Alzheimer's disease. Dement Geriatr Cogn Disord 17, 42-48.
17. Vogel A, Gade A, Stokholm J, Waldemar G (2005) Semantic memory impairment in the earliest phases of Alzheimer's disease. Dement Geriatr Cogn Disord 19, 75-81.
18. Ober BA (2002) RT and non-RT methodology for semantic priming research with Alzheimer's disease patients: A critical review. J Clin Exp Neuropsychol 24, 883-911.
19. Giffard B, Laisney M, Mezenge F, de la Sayette V, Eustache F, Desgranges B (2008) The neural substrates of semantic memory deficits in early Alzheimer's disease: Clues from semantic priming effects and FDG-PET. Neuropsychologia 46, 1657-1666.
20. Ober BA, Shenaut GK (1988) Lexical decision and priming in Alzheimer's disease. Neuropsychologia 26, 273-286.
21. Nebes RD, Martin DC, Horn LC (1984) Sparing of semantic memory in Alzheimer's disease. J Abnorm Psychol 93, 321-330.
22. Rogers SL, Friedman RB (2008) The underlying mechanisms of semantic memory loss in Alzheimer's disease and semantic dementia. Neuropsychologia 46, 12-21.
23. Chertkow H, Bub D, Bergman H, Bruemmer A, Merling A, Rothfleisch J (1994) Increased semantic priming in patients with dementia of the Alzheimer's type. J Clin Exp Neuropsychol 16, 608-622.
24. Grieder M, Crinelli RM, Koenig T, Wahlund LO, Dierks T, Wirth M (2012) Electrophysiological and behavioral correlates of stable automatic semantic retrieval in aging. Neuropsychologia 50, 160-171.
25. Wirth M, Horn H, Koenig T, Stein M, Federspiel A, Meier B, Michel CM, Strik W (2007) Sex differences in semantic processing: Event-related brain potentials distinguish between lower and higher order semantic analysis duringword reading. Cereb Cortex 17, 1987-1997.
26. Kutas M, Federmeier KD (2000) Electrophysiology reveals semantic memory use in language comprehension. Trends Cogn Sci 4, 463-470.
27. Khateb A, Pegna AJ, Landis T, Mouthon MS, Annoni JM (2010) On the origin of the N400 effects: An ERP waveform and source localization analysis in three matching tasks. Brain Topogr 23, 311-320.
28. Taylor JR, Olichney JM (2007) From amnesia to dementia: ERP studies of memory and language. Clin EEG Neurosci 38, 8-17.
29. Schwartz TJ, Kutas M, Butters N, Paulsen JS, Salmon DP (1996) Electrophysiological insights into the nature of the semantic deficit in Alzheimer's disease. Neuropsychologia 34, 827-841.
30. Iragui V, Kutas M, Salmon DP (1996) Event-related brain potentials during semantic categorization in normal aging and senile dementia of the Alzheimer's type. Electroencephalogr Clin Neurophysiol 100, 392-406.
31. Ford JM, Woodward SH, Sullivan EV, Isaacks BG, Tinklenberg JR, Yesavage JA, Roth WT (1996) N400 evidence of abnormal responses to speech in Alzheimer's disease. Electroencephalogr Clin Neurophysiol 99, 235-246.
32. Hurley RS, Paller KA, Rogalski EJ, Mesulam MM (2012) Neural mechanisms of object naming and word comprehension in primary progressive aphasia. J Neurosci 32, 4848-4855.
33. Revonsuo A, Portin R, Juottonen K, Rinne JO (1998) Semantic processing of spoken words in Alzheimer's disease: An electrophysiological study. J Cogn Neurosci 10, 408-420.
34. Ford JM, Askari N, Mathalon DH, Menon V, Gabrieli JD, Tinklenberg JR, Yesavage J (2001) Event-related brain potential evidence of spared knowledge in Alzheimer's disease. Psychol Aging 16, 161-176.
35. Auchterlonie S, Phillips NA, Chertkow H (2002) Behavioral and electrical brain measures of semantic priming in patients with Alzheimer's disease: Implications for access failure versus deterioration hypotheses. Brain Cogn 48, 264-267.
36. Olichney JM, Yang JC, Taylor J, Kutas M (2011) Cognitive event-related potentials: Biomarkers of synaptic dysfunction across the stages of Alzheimer's disease. J Alzheimers Dis 26(Suppl 3), 215-228.
37. Olichney JM, Taylor JR, Gatherwright J, Salmon DP, Bressler AJ, Kutas M, Iragui-Madoz VJ (2008) Patients with MCI and N400 or P600 abnormalities are at very high risk for conversion to dementia. Neurology 70, 1763-1770.
38. Hamberger MJ, Friedman D, Ritter W, Rosen J (1995) Event-related potential and behavioral correlates of semantic processing in Alzheimer's patients and normal controls. Brain Lang 48, 33-68.
39. Boxer AL, Rankin KP, Miller BL, Schuff N, Weiner M, Gorno-Tempini ML, Rosen HJ (2003) Cinguloparietal atrophy distinguishes Alzheimer disease from semantic dementia. Arch Neurol 60, 949-956.
40. Galton CJ, Patterson K, Graham K, Lambon-Ralph MA, Williams G, Antoun N, Sahakian BJ, Hodges JR (2001) Differing patterns of temporal atrophy in Alzheimer's disease and semantic dementia. Neurology 57, 216-225.
41. Rami L, Gomez-Anson B, Monte GC, Bosch B, Sanchez-Valle R, Molinuevo JL (2009) Voxel based morphometry features and follow-up of amnestic patients at high risk for Alzheimer's disease conversion. Int J Geriatr Psychiatry 24, 875-884.
42. MummeryCJ, Patterson K, Price CJ, Ashburner J, Frackowiak RS, Hodges JR (2000) A voxel-based morphometry study of semantic dementia: Relationship between temporal lobe atrophy and semantic memory. Ann Neurol 47, 36-45.
43. Rosen HJ, Gorno-Tempini ML, Goldman WP, Perry RJ, Schuff N,Weiner M, Feiwell R, Kramer JH, Miller BL (2002) Patterns of brain atrophy in frontotemporal dementia and semantic dementia. Neurology 58, 198-208.
44. Frings L, Mader I, Landwehrmeyer BG, Weiller C, Hull M, Huppertz HJ (2012) Quantifying change in individual subjects affected by frontotemporal lobar degeneration using automated longitudinal MRI volumetry. Hum Brain Mapp 33, 1526-1535.
45. Luckhaus C, Janner M, Cohnen M, Fluss MO, Teipel SJ, Grothe M, Hampel H, Kornhuber J, Ruther E, Peters O, Supprian T, Gaebel W, Modder U, Wittsack HJ (2010) A novel MRI-biomarker candidate for Alzheimer's disease composed of regional brain volume and perfusion variables. Eur J Neurol 17, 1437-1444.
46. Alsop DC, Dai W, Grossman M, Detre JA (2010) Arterial spin labeling blood flow MRI: Its role in the early characterization of Alzheimer's disease. J Alzheimers Dis 20, 871-880.
47. Chen Y, Wolk DA, Reddin JS, Korczykowski M, Martinez PM,Musiek ES, Newberg AB, Julin P, Arnold SE, Greenberg JH, Detre JA (2011) Voxel-level comparison of arterial spinlabeled perfusion MRI and FDG-PET in Alzheimer disease. Neurology 77, 1977-1985.
48. Johnson NA, Jahng GH, Weiner MW, Miller BL, Chui HC, Jagust WJ, Gorno-Tempini ML, Schuff N (2005) Pattern of cerebral hypoperfusion in Alzheimer disease and mild cognitive impairment measured with arterial spinlabelingMRimaging: Initial experience. Radiology 234, 851-859.
49. Alsop DC, Casement M, de Bazelaire C, Fong T, Press DZ (2008) Hippocampal hyperperfusion in Alzheimer's disease. Neuroimage 42, 1267-1274.
50. Dai W, Lopez OL, Carmichael OT, Becker JT, Kuller LH, Gach HM (2009) Mild cognitive impairment and alzheimer disease: Patterns of altered cerebral blood flow at MR imaging. Radiology 250, 856-866.
51. Fleisher AS, Podraza KM, Bangen KJ, Taylor C, Sherzai A, Sidhar K, Liu TT, Dale AM, Buxton RB (2009) Cerebral perfusion and oxygenation differences in Alzheimer's disease risk. Neurobiol Aging 30, 1737-1748.
52. Diehl J, Grimmer T, Drzezga A, Riemenschneider M, Forstl H, Kurz A (2004) Cerebral metabolic patterns at early stages of frontotemporal dementia and semantic dementia. A PET study. Neurobiol Aging 25, 1051-1056.
53. Michel CM, Seeck M, MurrayMM(2004) The speed of visual cognition. Suppl Clin Neurophysiol 57, 617-627.
54. Halgren E, Baudena P, Heit G, Clarke JM, Marinkovic K, Clarke M (1994) Spatio-temporal stages in face and word processing. I. Depth-recorded potentials in the human occipital, temporal and parietal lobes [corrected]. J Physiol Paris 88, 1-50.
55. Halgren E, Dhond RP, Christensen N, Van Petten C, Marinkovic K, Lewine JD, Dale AM (2002) N400-like magnetoencephalography responses modulated by semantic context, word frequency, and lexical class in sentences. Neuroimage 17, 1101-1116.
56. The ICD-10 Classification of Mental and Behavioral Disorders (1992) World Health Organization Geneva.
57. Haatveit BC, Sundet K, Hugdahl K, Ueland T, Melle I, Andreassen OA (2010) The validity of d prime as a working memory index: Results from the "Bergen n-back task". J Clin Exp Neuropsychol 32, 871-880.
58. Tran Y, Craig A, Boord P, Craig D (2004) Using independent component analysis to remove artifact from electroencephalographic measured during stuttered speech. Med Biol Eng Comput 42, 627-633.
59. Lehmann D, Skrandies W (1980) Reference-free identification of components of checkerboard-evoked multichannel potential fields. Electroencephalogr Clin Neurophysiol 48, 609-621.
60. Murray MM, Brunet D, Michel CM (2008) Topographic ERP analyses: A step-by-step tutorial review. Brain Topogr 20, 249-264.
61. Koenig T, KottlowM, Stein M, Melie-Garcia L (2011) Ragu: A free tool for the analysis of EEG and MEG event-related scalp field data using global randomization statistics. Comput Intell Neurosci 2011, 938925.
62. Koenig T, Melie-Garcia L (2009) Statistical analysis of multichannel scalp field data. In Electrical Neuroimaging, Michel CM, Koenig T, Brandeis D, Gianotti LRR, Wackermann J, eds. Cambridge University Press, New York, pp. 169-190.
63. Pascual-Marqui RD, Michel CM, Lehmann D (1995) Segmentation of brain electrical activity into microstates: Model estimation and validation. IEEE Trans Biomed Eng 42, 658-665.
64. Brandeis D, Naylor H, Halliday R, Callaway E, Yano L (1992) Scopolamine effects on visual information processing, attention, and event-related potential map latencies. Psychophysiology 29, 315-336.
65. Wu WC, Fernandez-Seara M, Detre JA, Wehrli FW, Wang J (2007) A theoretical and experimental investigation of the tagging efficiency of pseudocontinuous arterial spin labeling. Magn Reson Med 58, 1020-1027.
66. Dai W, Garcia D, de Bazelaire C, Alsop DC (2008) Continuous flow-driven inversion for arterial spin labeling using pulsed radio frequency and gradient fields. Magn Reson Med 60, 1488-1497.
67. Ashburner J, Friston KJ (2000) Voxel-based morphometry-the methods. Neuroimage 11, 805-821.
68. Good CD, Johnsrude IS, Ashburner J, Henson RN, Friston KJ, Frackowiak RS (2001) A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage 14, 21-36.
69. Wang J, Alsop DC, Song HK, Maldjian JA, Tang K, Salvucci AE, Detre JA (2003) Arterial transit time imaging with flow encoding arterial spin tagging (FEAST). Magn Reson Med 50, 599-607.
70. Federspiel A, Muller TJ, Horn H, Kiefer C, Strik WK (2006) Comparison of spatial and temporal pattern for fMRI obtained with BOLD and arterial spin labeling. J Neural Transm 113, 1403-1415.
71. Luh WM,Wong EC, Bandettini PA, Hyde JS (1999) QUIPSS II with thin-slice TI1 periodic saturation: A method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling. Magn Reson Med 41, 1246-1254.
72. Wang J,Wang Z, Aguirre GK, Detre JA (2005) To smooth or not to smooth?. ROC analysis of perfusion fMRI data. Magn Reson Imaging 23, 75-81.
73. Focke NK, Helms G, Kaspar S, Diederich C, Toth V, Dechent P, Mohr A, Paulus W (2011) Multi-site voxel-based morphometry-not quite there yet. Neuroimage 56, 1164-1170.
74. Jann K, Koenig T, Dierks T, Boesch C, Federspiel A (2010) Association of individual resting state EEG alpha frequency and cerebral blood flow. Neuroimage 51, 365-372.
75. Pulvermuller F, Assadollahi R, Elbert T (2001) Neuromagnetic evidence for early semantic access in word recognition. Eur J Neurosci 13, 201-205.
76. Hill H, Strube M, Roesch-Ely D, Weisbrod M (2002) Automatic vs. controlled processes in semantic priming-differentiation by event-related potentials. Int J Psychophysiol 44, 197-218.
77. Ober BA, Shenaut GK, Jagust WJ, Stillman RC (1991) Automatic semantic priming with various category relations in Alzheimer's disease and normal aging. Psychol Aging 6, 647-660.
78. Nebes RD (1989) Semantic memory in Alzheimer's disease. Psychol Bull 106, 377-394.
79. Fennema-Notestine C, Hagler DJ, Jr., McEvoy LK, Fleisher AS,Wu EH, Karow DS, Dale AM, Alzheimer's Disease Neuroimaging, Initiative (2009) Structural MRI biomarkers for preclinical and mild Alzheimer's disease. Hum Brain Mapp 30, 3238-3253.
80. Peters F, Majerus S, Collette F, Degueldre C, Del Fiore G, Laureys S, Moonen G, Salmon E (2009) Neural substrates of phonological and lexicosemantic representations in Alzheimer's disease. Hum Brain Mapp 30, 185-199.
81. McCarthy G, Nobre AC, Bentin S, Spencer DD (1995) Language-related field potentials in the anterior-medial temporal lobe: I. Intracranial distribution and neural generators. J Neurosci 15, 1080-1089.
82. Bobes MA, Garcia YF, Lopera F, Quiroz YT, Galan L, Vega M, Trujillo N, Valdes-Sosa M, Valdes-Sosa P (2010) ERP generator anomalies in presymptomatic carriers of the Alzheimer's disease E280A PS-1 mutation. Hum Brain Mapp 31, 247-265.