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Volumn 73, Issue 15, 2013, Pages 4697-4710

Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; K RAS PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PLACEBO; PROGESTERONE; PROGESTERONE RECEPTOR;

EID: 84881416118     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-0930     Document Type: Article
Times cited : (60)

References (49)
  • 1
    • 84860436812 scopus 로고    scopus 로고
    • Hormonal therapy in breast cancer: A model disease for the personalization of cancer care
    • Puhalla S, Bhattacharya S, Davidson NE. Hormonal therapy in breast cancer: a model disease for the personalization of cancer care. Mol Oncol 2012;6:222-36.
    • (2012) Mol Oncol , vol.6 , pp. 222-236
    • Puhalla, S.1    Bhattacharya, S.2    Davidson, N.E.3
  • 3
    • 84867551392 scopus 로고    scopus 로고
    • Landmarks in hormonal therapy for prostate cancer
    • Hammerer P, Madersbacher S. Landmarks in hormonal therapy for prostate cancer. BJU Int 2012;110(Suppl 1):23-9.
    • (2012) BJU Int , vol.110 , Issue.SUPPL. 1 , pp. 23-29
    • Hammerer, P.1    Madersbacher, S.2
  • 5
    • 78650194056 scopus 로고    scopus 로고
    • Endometrioid carcinoma of the endometrium: Pathologic and molecular features
    • Azueta A, Gatius S, Matias-Guiu X. Endometrioid carcinoma of the endometrium: pathologic and molecular features. Semin Diagn Pathol 2010;27:226-40.
    • (2010) Semin Diagn Pathol , vol.27 , pp. 226-240
    • Azueta, A.1    Gatius, S.2    Matias-Guiu, X.3
  • 6
    • 33750576103 scopus 로고    scopus 로고
    • Molecular and pathologic aspects of endometrial carcinogenesis
    • Hecht JL, Mutter GL. Molecular and pathologic aspects of endometrial carcinogenesis. J Clin Oncol 2006;24:4783-91.
    • (2006) J Clin Oncol , vol.24 , pp. 4783-4791
    • Hecht, J.L.1    Mutter, G.L.2
  • 7
    • 0014541472 scopus 로고
    • Estrogen replacement therapy
    • Acken HS Jr. Estrogen replacement therapy. Obstet Gynecol 1969;34: 46-9.
    • (1969) Obstet Gynecol , vol.34 , pp. 46-49
    • Acken Jr., H.S.1
  • 8
    • 0015831422 scopus 로고
    • Hypertrophy and hyperplasia in the mouse uterus after oestrogen treatment: An autoradiographic study
    • Martin L, Finn CA, Trinder G. Hypertrophy and hyperplasia in the mouse uterus after oestrogen treatment: an autoradiographic study. J Endocrinol 1973;56:133-44.
    • (1973) J Endocrinol , vol.56 , pp. 133-144
    • Martin, L.1    Finn, C.A.2    Trinder, G.3
  • 10
    • 18844398206 scopus 로고
    • Iatrogenic endometrial patterns
    • Charles D. Iatrogenic endometrial patterns. J Clin Pathol 1964;17: 205-12.
    • (1964) J Clin Pathol , vol.17 , pp. 205-212
    • Charles, D.1
  • 11
    • 76249116000 scopus 로고    scopus 로고
    • Role of progesterone in endometrial cancer
    • Kim JJ, Chapman-Davis E. Role of progesterone in endometrial cancer. Semin Reprod Med 2010;28:81-90.
    • (2010) Semin Reprod Med , vol.28 , pp. 81-90
    • Kim, J.J.1    Chapman-Davis, E.2
  • 12
    • 34548700355 scopus 로고    scopus 로고
    • Hormone therapy in advanced and recurrent endometrial cancer: A systematic review
    • Decruze SB, Green JA. Hormone therapy in advanced and recurrent endometrial cancer: a systematic review. Int J Gynecol Cancer 2007; 17:964-78.
    • (2007) Int J Gynecol Cancer , vol.17 , pp. 964-978
    • Decruze, S.B.1    Green, J.A.2
  • 14
    • 77956819536 scopus 로고    scopus 로고
    • Treatment for advanced and recurrent endometrial carcinoma: Combined modalities
    • Rauh-Hain JA, Del Carmen MG. Treatment for advanced and recurrent endometrial carcinoma: combined modalities. Oncologist 2010;15: 852-61.
    • (2010) Oncologist , vol.15 , pp. 852-861
    • Rauh-Hain, J.A.1    Del Carmen, M.G.2
  • 15
    • 15844426173 scopus 로고    scopus 로고
    • Role of stromal-epithelial interactions in hormonal responses
    • Cunha GR, Cooke PS, Kurita T. Role of stromal-epithelial interactions in hormonal responses. Arch Histol Cytol 2004;67:417-34.
    • (2004) Arch Histol Cytol , vol.67 , pp. 417-434
    • Cunha, G.R.1    Cooke, P.S.2    Kurita, T.3
  • 16
    • 84857762219 scopus 로고    scopus 로고
    • Epithelial progesterone receptor exhibits pleiotropic roles in uterine development and function
    • Franco HL, Rubel CA, Large MJ, Wetendorf M, Fernandez-Valdivia R, Jeong JW, et al. Epithelial progesterone receptor exhibits pleiotropic roles in uterine development and function. FASEB J 2012;26:1218-27.
    • (2012) FASEB J , vol.26 , pp. 1218-1227
    • Franco, H.L.1    Rubel, C.A.2    Large, M.J.3    Wetendorf, M.4    Fernandez-Valdivia, R.5    Jeong, J.W.6
  • 17
    • 78049315333 scopus 로고    scopus 로고
    • Cell-autonomous activation of the PI3-kinase pathway initiates endometrial cancer from adult uterine epithelium
    • Memarzadeh S, Zong Y, Janzen DM, Goldstein AS, Cheng D, Kurita T, et al. Cell-autonomous activation of the PI3-kinase pathway initiates endometrial cancer from adult uterine epithelium. Proc Natl Acad Sci U S A 2010;107:17298-303.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 17298-17303
    • Memarzadeh, S.1    Zong, Y.2    Janzen, D.M.3    Goldstein, A.S.4    Cheng, D.5    Kurita, T.6
  • 19
    • 33646739524 scopus 로고    scopus 로고
    • Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor
    • Xin L, Teitell MA, Lawson DA, Kwon A, Mellinghoff IK, Witte ON. Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor. Proc Natl Acad Sci U S A 2006;103:7789-94.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 7789-7794
    • Xin, L.1    Teitell, M.A.2    Lawson, D.A.3    Kwon, A.4    Mellinghoff, I.K.5    Witte, O.N.6
  • 20
    • 36649036989 scopus 로고    scopus 로고
    • Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor
    • Memarzadeh S, Xin L, Mulholland DJ, Mansukhani A,WuH, TeitellMA, et al. Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor. Cancer Cell 2007;12:572-85.
    • (2007) Cancer Cell , vol.12 , pp. 572-585
    • Memarzadeh, S.1    Xin, L.2    Mulholland, D.J.3    Mansukhani, A.4    Wu, H.5    Teitell, M.A.6
  • 22
    • 79958709933 scopus 로고    scopus 로고
    • Hypermethylation of the progesterone receptor A in constitutive antiprogestin- resistant mouse mammary carcinomas
    • Wargon V, Fernandez SV, Goin M, Giulianelli S, Russo J, Lanari C. Hypermethylation of the progesterone receptor A in constitutive antiprogestin- resistant mouse mammary carcinomas. Breast Cancer Res Treat 2011;126:319-32.
    • (2011) Breast Cancer Res Treat , vol.126 , pp. 319-332
    • Wargon, V.1    Fernandez, S.V.2    Goin, M.3    Giulianelli, S.4    Russo, J.5    Lanari, C.6
  • 23
    • 79952713255 scopus 로고    scopus 로고
    • A unique spectrum of somatic PIK3CA (p110alpha) mutations within primary endometrial carcinomas
    • Rudd ML, Price JC, Fogoros S, Godwin AK, Sgroi DC, Merino MJ, et al. A unique spectrum of somatic PIK3CA (p110alpha) mutations within primary endometrial carcinomas. Clin Cancer Res 2011;17:1331-40.
    • (2011) Clin Cancer Res , vol.17 , pp. 1331-1340
    • Rudd, M.L.1    Price, J.C.2    Fogoros, S.3    Godwin, A.K.4    Sgroi, D.C.5    Merino, M.J.6
  • 25
    • 33745289011 scopus 로고    scopus 로고
    • Regression of latent endometrial precancers by progestin infiltrated intrauterine device
    • Orbo A, Rise CE, Mutter GL. Regression of latent endometrial precancers by progestin infiltrated intrauterine device. Cancer Res 2006; 66:5613-7.
    • (2006) Cancer Res , vol.66 , pp. 5613-5617
    • Orbo, A.1    Rise, C.E.2    Mutter, G.L.3
  • 26
    • 1342300673 scopus 로고    scopus 로고
    • Involution of PTEN-null endometrial glands with progestin therapy
    • Zheng W, Baker HE, Mutter GL. Involution of PTEN-null endometrial glands with progestin therapy. Gynecol Oncol 2004;92:1008-13.
    • (2004) Gynecol Oncol , vol.92 , pp. 1008-1013
    • Zheng, W.1    Baker, H.E.2    Mutter, G.L.3
  • 27
    • 33847298630 scopus 로고    scopus 로고
    • Combined phospho-Akt and PTEN expressions associated with post-treatment hysterectomy after conservative progestin therapy in complex atypical hyperplasia and stage Ia, G1 adenocarcinoma of the endometrium
    • Minaguchi T, Nakagawa S, Takazawa Y, Nei T, Horie K, Fujiwara T, et al. Combined phospho-Akt and PTEN expressions associated with post-treatment hysterectomy after conservative progestin therapy in complex atypical hyperplasia and stage Ia, G1 adenocarcinoma of the endometrium. Cancer Lett 2007;248:112-22.
    • (2007) Cancer Lett , vol.248 , pp. 112-122
    • Minaguchi, T.1    Nakagawa, S.2    Takazawa, Y.3    Nei, T.4    Horie, K.5    Fujiwara, T.6
  • 28
    • 38049085766 scopus 로고    scopus 로고
    • Loss of phosphatase and tensin homologue deleted on chromosome 10 and phosphorylation of mammalian target of rapamycin are associated with progesterone refractory endometrial hyperplasia
    • Milam MR, Soliman PT, Chung LH, Schmeler KM, Bassett RL Jr, Broaddus RR, et al. Loss of phosphatase and tensin homologue deleted on chromosome 10 and phosphorylation of mammalian target of rapamycin are associated with progesterone refractory endometrial hyperplasia. Int J Gynecol Cancer 2008;18:146-51.
    • (2008) Int J Gynecol Cancer , vol.18 , pp. 146-151
    • Milam, M.R.1    Soliman, P.T.2    Chung, L.H.3    Schmeler, K.M.4    Bassett Jr., R.L.5    Broaddus, R.R.6
  • 29
    • 38749125159 scopus 로고    scopus 로고
    • Neither ovariectomy nor progestin treatment prevents endometrial neoplasia in pten+/ mice
    • Fyles A, Wood G, Li M, Manoukian AS, Gowing K, Khokha R, et al. Neither ovariectomy nor progestin treatment prevents endometrial neoplasia in pten+/ mice. Gynecol Oncol 2008;108:395-401.
    • (2008) Gynecol Oncol , vol.108 , pp. 395-401
    • Fyles, A.1    Wood, G.2    Li, M.3    Manoukian, A.S.4    Gowing, K.5    Khokha, R.6
  • 30
    • 79953295272 scopus 로고    scopus 로고
    • The synergistic effect of conditional Pten loss and oncogenic K-ras mutation on endometrial cancer development occurs via decreased progesterone receptor action
    • KimTH,WangJ, Lee KY, Franco HL, Broaddus RR, Lydon JP, et al. The synergistic effect of conditional Pten loss and oncogenic K-ras mutation on endometrial cancer development occurs via decreased progesterone receptor action. J Oncol 2010:139087.
    • (2010) J Oncol , pp. 139087
    • Kim, T.H.1    Wang, J.2    Lee, K.Y.3    Franco, H.L.4    Broaddus, R.R.5    Lydon, J.P.6
  • 31
    • 79956301068 scopus 로고    scopus 로고
    • Adenovirus mediated homozygous endometrial epithelial Pten deletion results in aggressive endometrial carcinoma
    • Joshi A, Ellenson LH. Adenovirus mediated homozygous endometrial epithelial Pten deletion results in aggressive endometrial carcinoma. Exp Cell Res 2011;317:1580-9.
    • (2011) Exp Cell Res , vol.317 , pp. 1580-1589
    • Joshi, A.1    Ellenson, L.H.2
  • 32
    • 84855909747 scopus 로고    scopus 로고
    • The epidemiology of endometrial and ovarian cancer
    • Cramer DW. The epidemiology of endometrial and ovarian cancer. Hematol Oncol Clin North Am 2012;26:1-12.
    • (2012) Hematol Oncol Clin North Am , vol.26 , pp. 1-12
    • Cramer, D.W.1
  • 33
    • 34347340589 scopus 로고    scopus 로고
    • Histologic alterations in endometrial hyperplasia and well-differentiated carcinoma treated with progestins
    • Wheeler DT, Bristow RE, Kurman RJ. Histologic alterations in endometrial hyperplasia and well-differentiated carcinoma treated with progestins. Am J Surg Pathol 2007;31:988-98.
    • (2007) Am J Surg Pathol , vol.31 , pp. 988-998
    • Wheeler, D.T.1    Bristow, R.E.2    Kurman, R.J.3
  • 34
    • 0021930760 scopus 로고
    • Effects of aging and obesity on aromatase activity of human adipose cells
    • Cleland WH, Mendelson CR, Simpson ER. Effects of aging and obesity on aromatase activity of human adipose cells. J Clin Endocrinol Metab 1985;60:174-7.
    • (1985) J Clin Endocrinol Metab , vol.60 , pp. 174-177
    • Cleland, W.H.1    Mendelson, C.R.2    Simpson, E.R.3
  • 36
    • 0026511556 scopus 로고
    • Oestrogen and progesterone receptor immunocytochemistry in human hyperplastic and neoplastic endometrium
    • Snijders MP, de Goeij AF, Koudstaal J, Thunnissen EB, de Haan J, Bosman FT. Oestrogen and progesterone receptor immunocytochemistry in human hyperplastic and neoplastic endometrium. J Pathol 1992;166:171-7.
    • (1992) J Pathol , vol.166 , pp. 171-177
    • Snijders, M.P.1    De Goeij, A.F.2    Koudstaal, J.3    Thunnissen, E.B.4    De Haan, J.5    Bosman, F.T.6
  • 37
    • 14844333582 scopus 로고    scopus 로고
    • Hormonal therapy of endometrial cancer
    • Markman M. Hormonal therapy of endometrial cancer. Eur J Cancer 2005;41:673-5.
    • (2005) Eur J Cancer , vol.41 , pp. 673-675
    • Markman, M.1
  • 38
    • 0033003177 scopus 로고    scopus 로고
    • Oral medroxyprogesterone acetate in the treatment of advanced or recurrent endometrial carcinoma: A dose-response study by the Gynecologic Oncology Group
    • Thigpen JT, Brady MF, Alvarez RD, Adelson MD, Homesley HD, Manetta A, et al. Oral medroxyprogesterone acetate in the treatment of advanced or recurrent endometrial carcinoma: a dose-response study by the Gynecologic Oncology Group. J Clin Oncol 1999;17: 1736-44.
    • (1999) J Clin Oncol , vol.17 , pp. 1736-1744
    • Thigpen, J.T.1    Brady, M.F.2    Alvarez, R.D.3    Adelson, M.D.4    Homesley, H.D.5    Manetta, A.6
  • 39
    • 33748666407 scopus 로고    scopus 로고
    • Generation of a mouse for conditional excision of progesterone receptor
    • Hashimoto-Partyka MK, Lydon JP, Iruela-Arispe ML. Generation of a mouse for conditional excision of progesterone receptor. Genesis 2006;44:391-5.
    • (2006) Genesis , vol.44 , pp. 391-395
    • Hashimoto-Partyka, M.K.1    Lydon, J.P.2    Iruela-Arispe, M.L.3
  • 40
    • 0031735444 scopus 로고    scopus 로고
    • Stromal progesterone receptors mediate the inhibitory effects of progesterone on estrogen-induced uterine epithelial cell deoxyribonucleic acid synthesis
    • Kurita T, Young P, Brody JR, Lydon JP, O'Malley BW, Cunha GR. Stromal progesterone receptors mediate the inhibitory effects of progesterone on estrogen-induced uterine epithelial cell deoxyribonucleic acid synthesis. Endocrinology 1998;139:4708-13.
    • (1998) Endocrinology , vol.139 , pp. 4708-4713
    • Kurita, T.1    Young, P.2    Brody, J.R.3    Lydon, J.P.4    O'Malley, B.W.5    Cunha, G.R.6
  • 41
    • 79951828774 scopus 로고    scopus 로고
    • The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2
    • Li Q, Kannan A, DeMayo FJ, Lydon JP, Cooke PS, Yamagishi H, et al. The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2. Science 2011;331:912-6.
    • (2011) Science , vol.331 , pp. 912-916
    • Li, Q.1    Kannan, A.2    Demayo, F.J.3    Lydon, J.P.4    Cooke, P.S.5    Yamagishi, H.6
  • 42
    • 0029934262 scopus 로고    scopus 로고
    • Methylation of estrogen and progesterone receptor gene 50 CpG islands correlates with lack of estrogen and progesterone receptor gene expression in breast tumors
    • Lapidus RG, Ferguson AT, Ottaviano YL, Parl FF, Smith HS, Weitzman SA, et al. Methylation of estrogen and progesterone receptor gene 50 CpG islands correlates with lack of estrogen and progesterone receptor gene expression in breast tumors. Clin Cancer Res 1996;2:805-10.
    • (1996) Clin Cancer Res , vol.2 , pp. 805-810
    • Lapidus, R.G.1    Ferguson, A.T.2    Ottaviano, Y.L.3    Parl, F.F.4    Smith, H.S.5    Weitzman, S.A.6
  • 43
    • 0035139039 scopus 로고    scopus 로고
    • Progesterone receptor B gene inactivation and CpG hypermethylation in human uterine endometrial cancer
    • Sasaki M, Dharia A, Oh BR, Tanaka Y, Fujimoto S, Dahiya R. Progesterone receptor B gene inactivation and CpG hypermethylation in human uterine endometrial cancer. Cancer Res 2001;61:97-102.
    • (2001) Cancer Res , vol.61 , pp. 97-102
    • Sasaki, M.1    Dharia, A.2    Oh, B.R.3    Tanaka, Y.4    Fujimoto, S.5    Dahiya, R.6
  • 44
    • 0025239785 scopus 로고
    • Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B
    • Kastner P, Krust A, Turcotte B, Stropp U, Tora L, Gronemeyer H, et al. Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J 1990;9:1603-14.
    • (1990) EMBO J , vol.9 , pp. 1603-1614
    • Kastner, P.1    Krust, A.2    Turcotte, B.3    Stropp, U.4    Tora, L.5    Gronemeyer, H.6
  • 47
    • 84866147755 scopus 로고    scopus 로고
    • Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian target of rapamycin complex 1
    • Tanwar PS, Kaneko-Tarui T, Zhang L, Tanaka Y, Crum CP, Teixeira JM. Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian target of rapamycin complex 1. PLoS Genet 2012;8:e1002906.
    • (2012) PLoS Genet , vol.8
    • Tanwar, P.S.1    Kaneko-Tarui, T.2    Zhang, L.3    Tanaka, Y.4    Crum, C.P.5    Teixeira, J.M.6
  • 49
    • 84860321700 scopus 로고    scopus 로고
    • Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
    • Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher- Sananikone E, et al. Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell 2012;149: 656-70.
    • (2012) Cell , vol.149 , pp. 656-670
    • Ying, H.1    Kimmelman, A.C.2    Lyssiotis, C.A.3    Hua, S.4    Chu, G.C.5    Fletcher-Sananikone, E.6


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