Emerging mechanisms of glutathione-dependent chemistry in biology and disease

Journal of Cellular Biochemistry

Volumn 114, Issue 9, 2013, Pages 1962-1968

  Janssen Heininger, Yvonne M W ^a   Nolin, James D ^a   Hoffman, Sidra M ^a   Van Der Velden, Jos L ^a   Tully, Jane E ^a   Lahue, Karolyn G ^a   Abdalla, Sarah T ^a   Chapman, David G ^a   Reynaert, Niki L ^b   Van Der Vliet, Albert ^a   Anathy, Vikas ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

BIOTIN SWITCH; GLUTAREDOXIN 1; PROTEIN S GLUTATHIONYLATION; REDOX

Indexed keywords

CYSTEINE; GLUTATHIONE; THIOL;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN; OXIDATION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROCESSING;

EID: 84881384073     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24551     Document Type: Article

References (50)

1. Aesif SW, Anathy V, Havermans M, Guala AS, Ckless K, Taatjes DJ, Janssen-Heininger YM,. 2009. In situ analysis of protein S-glutathionylation in lung tissue using glutaredoxin-1-catalyzed cysteine derivatization. Am J Pathol 175: 36-45.
2. Altenhofer S, Kleikers PW, Radermacher KA, Scheurer P, Rob Hermans JJ, Schiffers P, Ho H, Wingler K, Schmidt HH,. 2012. The NOX toolbox: validating the role of NADPH oxidases in physiology and disease. Cell Mol Life Sci 69: 2327-2343.
3. Anathy V, Roberson E, Cunniff B, Nolin JD, Hoffman S, Spiess P, Guala AS, Lahue KG, Goldman D, Flemer S, van der Vliet A, Heintz NH, Budd RC, Tew KD, Janssen-Heininger YM,. 2012a. Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis. Mol Cell Biol 32: 3464-3478.
4. Anathy V, Roberson EC, Guala AS, Godburn KE, Budd RC, Janssen-Heininger YM,. 2012b. Redox-based regulation of apoptosis: S-glutathionylation as a regulatory mechanism to control cell death. Antioxid Redox Signal 16: 496-505.
5. Benhar M, Forrester MT, Hess DT, Stamler JS,. 2008. Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. Science 320: 1050-1054.
6. Bulleid NJ, Ellgaard L,. 2011. Multiple ways to make disulfides. Trends Biochem Sci 36: 485-492.
7. Chakravarthi S, Jessop CE, Bulleid NJ,. 2006. The role of glutathione in disulphide bond formation and endoplasmic-reticulum-generated oxidative stress. EMBO Rep 7: 271-275.
8. Chen K, Kirber MT, Xiao H, Yang Y, Keaney JF, Jr., 2008. Regulation of ROS signal transduction by NADPH oxidase 4 localization. J Cell Biol 181: 1129-1139.
9. Coppo L, Ghezzi P,. 2011. Thiol regulation of pro-inflammatory cytokines and innate immunity: protein S-thiolation as a novel molecular mechanism. Biochem Soc Trans 39: 1268-1272.
10. Dalle-Donne I, Rossi R, Giustarini D, Colombo R, Milzani A,. 2007. S-glutathionylation in protein redox regulation. Free Radic Biol Med 43: 883-898.
11. Edgar RS, Green EW, Zhao Y, van Ooijen G, Olmedo M, Qin X, Xu Y, Pan M, Valekunja UK, Feeney KA, Maywood ES, Hastings MH, Baliga NS, Merrow M, Millar AJ, Johnson CH, Kyriacou CP, O'Neill JS, Reddy AB,. 2012. Peroxiredoxins are conserved markers of circadian rhythms. Nature 485: 459-464.
12. Findlay VJ, Townsend DM, Morris TE, Fraser JP, He L, Tew KD,. 2006. A novel role for human sulfiredoxin in the reversal of glutathionylation. Cancer Res 66: 6800-6806.
13. Finkel T,. 2011. Signal transduction by reactive oxygen species. J Cell Biol 194: 7-15.
14. Finkelstein EI, Ruben J, Koot CW, Hristova M, van der Vliet A,. 2005. Regulation of constitutive neutrophil apoptosis by the alpha,beta-unsaturated aldehydes acrolein and 4-hydroxynonenal. Am J Physiol Lung Cell Mol Physiol 289: L1019-L1028.
15. Hess DT, Stamler JS,. 2012. Regulation by S-nitrosylation of protein post-translational modification. J Biol Chem 287: 4411-4418.
16. Hoffman SM, Tully JE, Lahue KG, Anathy V, Nolin JD, Guala AS, van der Velden JL, Ho YS, Aliyeva M, Daphtary N, Lundblad LK, Irvin CG, Janssen-Heininger YM,. 2012. Genetic ablation of glutaredoxin-1 causes enhanced resolution of airways hyperresponsiveness and mucus metaplasia in mice with allergic airways disease. Am J Physiol Lung Cell Mol Physiol 303: L528-L538.
17. Jacob C,. 2011. Redox signalling via the cellular thiolstat. Biochem Soc Trans 39: 1247-1253.
18. Janssen-Heininger YM, Mossman BT, Heintz NH, Forman HJ, Kalyanaraman B, Finkel T, Stamler JS, Rhee SG, van der Vliet A,. 2008. Redox-based regulation of signal transduction: principles, pitfalls, and promises. Free Radic Biol Med 45: 1-17.
19. Jeong W, Bae SH, Toledano MB, Rhee SG,. 2012. Role of sulfiredoxin as a regulator of peroxiredoxin function and regulation of its expression. Free Radic Biol Med 53: 447-456.
20. Klomsiri C, Karplus PA, Poole LB,. 2011. Cysteine-based redox switches in enzymes. Antioxid Redox Signal 14: 1065-1077.
21. Kuipers I, Louis R, Manise M, Dentener MA, Irvin CG, Janssen-Heininger YM, Brightling CE, Wouters EF, Reynaert NL,. 2013. Increased glutaredoxin-1 and decreased protein S-glutathionylation in sputum of asthmatics. Eur Respir J 41: 469-472.
22. Kuzin B, Roberts I, Peunova N, Enikolopov G,. 1996. Nitric oxide regulates cell proliferation during Drosophila development. Cell 87: 639-649.
23. Lee S, Kim SM, Lee RT,. 2013. Thioredoxin and thioredoxin target proteins: from molecular mechanisms to functional significance. Antioxid Redox Signal 18: 1165-1207.
24. Lillig CH, Berndt C, Holmgren A,. 2008. Glutaredoxin systems. Biochim Biophys Acta 1780: 1304-1317.
25. Mahmood DF, Abderrazak A, Khadija EH, Simmet T, Rouis M,. 2013. The thioredoxin system as a therapeutic target in human health and disease. Antioxid Redox Signal Feb 26 [Epub ahead of print].
26. Manevich Y, Fisher AB,. 2005. Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism. Free Radic Biol Med 38: 1422-1432.
27. Marcos V, Zhou Z, Yildirim AO, Bohla A, Hector A, Vitkov L, Wiedenbauer EM, Krautgartner WD, Stoiber W, Belohradsky BH, Rieber N, Kormann M, Koller B, Roscher A, Roos D, Griese M, Eickelberg O, Doring G, Mall MA, Hartl D,. 2010. CXCR2 mediates NADPH oxidase-independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation. Nat Med 16: 1018-1023.
28. Marino SM, Gladyshev VN,. 2012. Analysis and functional prediction of reactive cysteine residues. J Biol Chem 287: 4419-4425.
29. Mieyal JJ, Gallogly MM, Qanungo S, Sabens EA, Shelton MD,. 2008. Molecular mechanisms and clinical implications of reversible protein S-glutathionylation. Antioxid Redox Signal 10: 1941-1988.
30. Nguyen VD, Saaranen MJ, Karala AR, Lappi AK, Wang L, Raykhel IB, Alanen HI, Salo KE, Wang CC, Ruddock LW,. 2011. Two endoplasmic reticulum PDI peroxidases increase the efficiency of the use of peroxide during disulfide bond formation. J Mol Biol 406: 503-515.
31. Oakley FD, Abbott D, Li Q, Engelhardt JF,. 2009a. Signaling components of redox active endosomes: the redoxosomes. Antioxid Redox Signal 11: 1313-1333.
32. Oakley FD, Smith RL, Engelhardt JF,. 2009b. Lipid rafts and caveolin-1 coordinate interleukin-1beta (IL-1beta)-dependent activation of NFkappaB by controlling endocytosis of Nox2 and IL-1beta receptor 1 from the plasma membrane. J Biol Chem 284: 33255-33264.
33. Paul BD, Snyder SH,. 2012. H(2)S signalling through protein sulfhydration and beyond. Nat Rev Mol Cell Biol 13: 499-507.
34. Peltoniemi MJ, Rytila PH, Harju TH, Soini YM, Salmenkivi KM, Ruddock LW, Kinnula VL,. 2006. Modulation of glutaredoxin in the lung and sputum of cigarette smokers and chronic obstructive pulmonary disease. Respir Res 7: 133.
35. Rahman I, Kode A, Biswas SK,. 2006. Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method. Nat Protoc 1: 3159-3165.
36. Resh MD,. 2006. Palmitoylation of ligands, receptors, and intracellular signaling molecules. Sci STKE 2006: re14.
37. Reynaert NL, Ckless K, Guala AS, Wouters EF, van der Vliet A, Janssen-Heininger YM,. 2006. In situ detection of S-glutathionylated proteins following glutaredoxin-1 catalyzed cysteine derivatization. Biochim Biophys Acta 1760: 380-387.
38. Reynaert NL, Wouters EF, Janssen-Heininger YM,. 2007. Modulation of glutaredoxin-1 expression in a mouse model of allergic airway disease. Am J Respir Cell Mol Biol 36: 147-151.
39. Rossi A, Kapahi P, Natoli G, Takahashi T, Chen Y, Karin M, Santoro MG,. 2000. Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. Nature 403: 103-108.
40. Rutkevich LA, Williams DB,. 2012. Vitamin K epoxide reductase contributes to protein disulfide formation and redox homeostasis within the endoplasmic reticulum. Mol Biol Cell 23: 2017-2027.
41. Seo YH, Carroll KS,. 2009. Profiling protein thiol oxidation in tumor cells using sulfenic acid-specific antibodies. Proc Natl Acad Sci USA 106: 16163-16168.
42. Seo YH, Carroll KS,. 2011. Quantification of protein sulfenic acid modifications using isotope-coded dimedone and iododimedone. Angew Chem Int Ed Engl 50: 1342-1345.
43. Sham D, Wesley UV, Hristova M, van der Vliet A,. 2013. ATP-mediated transactivation of the epidermal growth factor receptor in airway epithelial cells involves DUOX1-dependent oxidation of Src and ADAM17. PLoS ONE 8: e54391.
44. Stroher E, Millar AH,. 2012. The biological roles of glutaredoxins. Biochem J 446: 333-348.
45. Tavender TJ, Springate JJ, Bulleid NJ,. 2010. Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum. EMBO J 29: 4185-4197.
46. Townsend DM, Manevich Y, He L, Hutchens S, Pazoles CJ, Tew KD,. 2009. Novel role for glutathione S-transferase pi. Regulator of protein S-glutathionylation following oxidative and nitrosative stress. J Biol Chem 284: 436-445.
47. Winterbourn CC, Hampton MB,. 2008. Thiol chemistry and specificity in redox signaling. Free Radic Biol Med 45: 549-561.
48. Xiong Y, Uys JD, Tew KD, Townsend DM,. 2011. S-glutathionylation: from molecular mechanisms to health outcomes. Antioxid Redox Signal 15: 233-270.
49. Yoo SK, Freisinger CM, LeBert DC, Huttenlocher A,. 2012. Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish. J Cell Biol 199: 225-234.
50. Zito E, Melo EP, Yang Y, Wahlander A, Neubert TA, Ron D,. 2010. Oxidative protein folding by an endoplasmic reticulum-localized peroxiredoxin. Mol Cell 40: 787-797.