Increased glutaredoxin-1 and decreased protein S-glutathionylation in sputum of asthmatics

European Respiratory Journal

Volumn 41, Issue 2, 2013, Pages 469-472

  Kuipers, Ine ^a   Louis, Renaud ^b   Manise, Maite ^b   Dentener, Mieke A ^a   Irvin, Charles G ^c   Janssen Heininger, Yvonne M W ^d   Brightling, Christopher E ^e   Wouters, Emiel F M ^a   Reynaert, Niki L ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF VERMONT   (United States)

^e UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAREDOXIN; GLUTAREDOXIN 1; GLUTATHIONE; UNCLASSIFIED DRUG;

ADULT; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; FEMALE; FORCED EXPIRATORY VOLUME; HOMEOSTASIS; HUMAN; LETTER; LUNG ALVEOLUS MACROPHAGE; MALE; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN S GLUTATHIONYLATION; SPUTUM LEVEL;

ADULT; ANTIOXIDANTS; ASTHMA; FEMALE; GENE EXPRESSION REGULATION; GLUTAREDOXINS; GLUTATHIONE; HUMANS; MALE; MIDDLE AGED; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN S; SMOKING; SPUTUM;

EID: 84873330660     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00115212     Document Type: Letter

References (9)

1. Reynaert NL. Glutathione biochemistry in asthma. Biochim Biophys Acta 2011; 1810: 1045-1051.
2. Xiong Y, Uys JD, Tew KD, et al. S-glutathionylation: from molecular mechanisms to health outcomes. Antioxid Redox Signal 2011; 15: 233-270.
3. Peltoniemi MJ, Rytila PH, Harju TH, et al. Modulation of glutaredoxin in the lung and sputum of cigarette smokers and chronic obstructive pulmonary disease. Respir Res 2006; 7: 133.
4. Reynaert NL, Wouters EF, Janssen-Heininger YM. Modulation of glutaredoxin-1 expression in a mouse model of allergic airway disease. Am J Respir Cell Mol Biol 2007; 36: 147-151.
5. Brightling CE. Sputum induction in asthma: A research technique or a clinical toolChest 2006; 129: 503-504.
6. Nagai K, Betsuyaku T, Konno S, et al. Diversity of protein carbonylation in allergic airway inflammation. Free Radic Res 2008; 42: 921-929.
7. Peltoniemi M, Kaarteenaho-Wiik R, Saily M, et al. Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-b in vitro and in interstitial lung diseases in vivo. Hum Pathol 2004; 35: 1000-1007.
8. Lundberg M, Fernandes AP, Kumar S, et al. Cellular and plasma levels of human glutaredoxin 1 and 2 detected by sensitive ELISA systems. Biochem Biophys Res Commun 2004; 319: 801-809.
9. Aesif SW, Anathy V, Guala AS, et al. Ablation of glutaredoxin-1 attenuates lipopolysaccharide-induced lung inflammation and alveolar macrophage activation. Am J Respir CellMol Biol 2011; 44: 491-499.