Anti-VCAM-1 and anti-E-selectin SAINT-O-somes for selective delivery of siRNA into inflammation-activated primary endothelial cells

Molecular Pharmaceutics

Volumn 10, Issue 8, 2013, Pages 3033-3044

  Kowalski, Piotr S ^a   Lintermans, Lucas L ^a   Morselt, Henriëtte W M ^a   Leus, Niek G J ^a   Ruiters, Marcel H J ^a,b   Molema, Grietje ^a   Kamps, Jan A A M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b Synvolux Therapeutics   (Netherlands)

Author keywords

adhesion molecules; endothelium; liposomes; SAINT; siRNA delivery; Tumor Necrosis Factor

Indexed keywords

1 METHYL 4 (9 DIOLEYL)METHYL PYRIDINIUM CHLORIDE LIPOSOME; CADHERIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; LIPOSOME; MESSENGER RNA; RIBONUCLEASE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOTOXICITY; DEGRADATION; DOWN REGULATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; ENCAPSULATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES; E-SELECTIN; ENDOTHELIAL CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; LIPOSOMES; MALE; MICE; PARTICLE SIZE; RNA, SMALL INTERFERING; TUMOR NECROSIS FACTORS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84881343354     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp4001124     Document Type: Article

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