The Curcumin Analog EF24 Targets NF-κB and miRNA-21, and Has Potent Anticancer Activity In Vitro and In Vivo

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Yang, Chuan He ^a   Yue, Junming ^a   Sims, Michelle ^a   Pfeffer, Lawrence M ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,5 BIS(2 FLUOROBENZYLIDENE) 4 PIPERIDINONE; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; KI 67 ANTIGEN; MICRORNA; MICRORNA 10A; MICRORNA 206; MICRORNA 21; MICRORNA 24; MICRORNA 26A; MICRORNA 29A; MICRORNA 30B; MICRORNA 345; MICRORNA 409; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; STAT PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL DESTRUCTION; CANCER INHIBITION; CANCER SURVIVAL; CCND1 GENE; CCNE1 GENE; CDK2 GENE; CDK4 GENE; CDK6 GENE; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG TARGETING; ENZYME INHIBITION; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LUNG METASTASIS; MALE; METASTASIS INHIBITION; MOUSE; NONHUMAN; ONCOGENE; PDCD4 GENE; PROSTATE CANCER; PTEN GENE; SURVIVAL TIME; TUMOR SUPPRESSOR GENE; TUMOR VOLUME; UPREGULATION;

EID: 84881342707     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071130     Document Type: Article

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