Determination of drug release kinetics from nanoparticles: Overcoming pitfalls of the dynamic dialysis method

Molecular Pharmaceutics

Volumn 10, Issue 8, 2013, Pages 3076-3089

  Modi, Sweta ^a,b   Anderson, Bradley D ^a  

^a University of Kentucky   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

drug delivery systems; dynamic dialysis; lipid bilayers; liposomes; mathematical models; membrane binding; partition coefficient; permeability

Indexed keywords

1,2 DIMYRISTOYL SN GLYCERO SN GLYCERO 3 PHOSPHOCHOLINE; 1,2 DISTEAROYL SN GLYCERO 3 PHOSPHATIDYLCHOLINE; 7 TERT BUTYLDIMETHYLSILYL 10 HYDROXYCAMPTOTHECIN; AR 67; CAMPTOTHECIN DERIVATIVE; DEXAMETHASONE; DIPALMITOYLPHOSPHATIDYLCHOLINE; LIPID; LIPOSOME; NANOPARTICLE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; DIALYSIS; DIALYSIS MEMBRANE; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG TRANSPORT; DYNAMIC DIALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS; LIGHT SCATTERING; LIPID ANALYSIS; LIPID BILAYER; MATHEMATICAL MODEL; MEMBRANE BINDING; MEMBRANE PERMEABILITY; MEMBRANE TRANSPORT; NANOTECHNOLOGY; PARTICLE SIZE; PARTITION COEFFICIENT; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

DEXAMETHASONE; DRUG DELIVERY SYSTEMS; KINETICS; LIPID BILAYERS; LIPOSOMES; MODELS, THEORETICAL; NANOPARTICLES;

EID: 84881334214     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400154a     Document Type: Article

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