The antiestrogen 4-hydroxytamoxifen protects against isotretinoin-induced permeability transition and bioenergetic dysfunction of liver mitochondria: Comparison with tamoxifen

Journal of Bioenergetics and Biomembranes

Volumn 45, Issue 4, 2013, Pages 383-396

  Silva, Filomena S G ^a,b   Ribeiro, Mariana P C ^a,b   Santos, Maria S ^a,c   Rocha Pereira, Petronila ^d,f   Santos Silva, Alice ^e,f   Custódio, José B A ^a,b,g  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF BEIRA INTERIOR   (Portugal)

^e UNIVERSITY OF PORTO   (Portugal)

^f UNIVERSITY OF PORTO   (Portugal)

^g Azinhaga de Santa Comba   (Portugal)

Author keywords

4 hydroxytamoxifen; Isotretinoin; Mitochondrial permeability transition; Oxidative phosphorylation system; Tamoxifen

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; AFIMOXIFENE; CYCLOSPORIN A; ISOTRETINOIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); TAMOXIFEN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOENERGY; CELL MEMBRANE DEPOLARIZATION; CELL PROTECTION; CONCENTRATION (PARAMETERS); ENERGY YIELD; LIVER MITOCHONDRION; LIVER TOXICITY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PROTEIN PHOSPHORYLATION; RAT;

RATTUS;

ANIMALS; ANTINEOPLASTIC AGENTS, HORMONAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CELL MEMBRANE PERMEABILITY; DISEASE MODELS, ANIMAL; DRUG INTERACTIONS; ENERGY METABOLISM; ESTROGEN RECEPTOR MODULATORS; ISOTRETINOIN; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, LIVER; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; OXIDATIVE PHOSPHORYLATION; RATS; RATS, WISTAR; TAMOXIFEN;

EID: 84881312135     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-013-9517-9     Document Type: Article

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