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Volumn 162, Issue 6, 2010, Pages 1172-1179

Advice on the safe introduction and continued use of isotretinoin in acne in the U.K. 2010

Author keywords

Adverse effects; Depression; Isotretinoin; Pregnancy prevention plan; Safe use; Teratogen

Indexed keywords

ANTIBIOTIC AGENT; BEXAROTENE; ETRETINATE; ISOTRETINOIN; RETINOL;

EID: 77952712238     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2010.09836.x     Document Type: Review
Times cited : (79)

References (52)
  • 1
    • 33748693116 scopus 로고    scopus 로고
    • Disorders of the sebaceous glands
    • Burns, D.A. Breathnach, S.M. Cox, N.H. Griffiths, C.E.M. eds7th edn.
    • Cunliffe WJ, Simpson N. Disorders of the sebaceous glands. In : Rook's Textbook of Dermatology (Burns DA, Breathnach SM, Cox NH, Griffiths CEM, eds 7th edn.
    • Rook's Textbook of Dermatology
    • Cunliffe, W.J.1    Simpson, N.2
  • 4
    • 0034806094 scopus 로고    scopus 로고
    • Safety issues in isotretinoin therapy
    • Hanson N, Leachman S. Safety issues in isotretinoin therapy. Semin Cutan Med Surg 2001 20 : 166 183.
    • (2001) Semin Cutan Med Surg , vol.20 , pp. 166-183
    • Hanson, N.1    Leachman, S.2
  • 5
    • 0032492276 scopus 로고    scopus 로고
    • Acne drug is linked to severe depression
    • Josefson D. Acne drug is linked to severe depression. BMJ 1998 316 : 723.
    • (1998) BMJ , vol.316 , pp. 723
    • Josefson, D.1
  • 6
    • 77952711754 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration. Available at. last accessed 28 March 2010)
    • U.S. Food and Drug Administration. iPLEDGE 2007 Update. Available at : http://www.fda.gov/Drugs/DrugSafety/ PostmarketDrugSafetyInformationforPatientsandProviders/ucm094306.htm (last accessed 28 March 2010).
    • IPLEDGE 2007 Update
  • 7
    • 0030807071 scopus 로고    scopus 로고
    • Roaccutane treatment guidelines: Results of an international survey
    • Cunliffe WJ, van de Kerkhof PCM, Caputo R et al. Roaccutane treatment guidelines: Results of an international survey. Dermatology 1997 194 : 351 357.
    • (1997) Dermatology , vol.194 , pp. 351-357
    • Cunliffe, W.J.1    Van De Kerkhof, P.C.M.2    Caputo, R.3
  • 8
    • 39049094170 scopus 로고    scopus 로고
    • Pitfalls of prescribing acne therapies including isotretinoin for pilots
    • Taibjee SM, Charles-Holmes R. Pitfalls of prescribing acne therapies including isotretinoin for pilots. Br J Dermatol 2007 158 : 653 655.
    • (2007) Br J Dermatol , vol.158 , pp. 653-655
    • Taibjee, S.M.1    Charles-Holmes, R.2
  • 9
    • 0027132550 scopus 로고
    • Isotretinoin therapy for acne vulgaris: A re-evaluation of the need for measurements of plasma lipids and liver function tests
    • Barth JH, Macdonald-Hull SP, Mark J et al. Isotretinoin therapy for acne vulgaris: A re-evaluation of the need for measurements of plasma lipids and liver function tests. Br J Dermatol 1993 129 : 704 707.
    • (1993) Br J Dermatol , vol.129 , pp. 704-707
    • Barth, J.H.1    MacDonald-Hull, S.P.2    Mark, J.3
  • 10
    • 0035040049 scopus 로고    scopus 로고
    • Analysis of laboratory data in acne patients treated with isotretinoin: Is there really a need to perform routine laboratory tests?
    • Alcalay J, Landau M, Zucker A. Analysis of laboratory data in acne patients treated with isotretinoin: is there really a need to perform routine laboratory tests? J Dermatolog Treat 2001 12 : 9 12.
    • (2001) J Dermatolog Treat , vol.12 , pp. 9-12
    • Alcalay, J.1    Landau, M.2    Zucker, A.3
  • 11
    • 33747616429 scopus 로고    scopus 로고
    • A population-based analysis of laboratory abnormalities during isotretinoin therapy for acne vulgaris
    • Zane LT, Leyden WA, Marqueling AL, Manos MM. A population-based analysis of laboratory abnormalities during isotretinoin therapy for acne vulgaris. Arch Dermatol 2006 142 : 1016 1022.
    • (2006) Arch Dermatol , vol.142 , pp. 1016-1022
    • Zane, L.T.1    Leyden, W.A.2    Marqueling, A.L.3    Manos, M.M.4
  • 12
    • 0037117563 scopus 로고    scopus 로고
    • High risk for hyperlipidemia and the metabolic syndrome after an episode of hypertriglyceridemia during 13-cis retinoic acid therapy for acne: A pharmacogenetic study
    • Rodondi N, Darioli R, Ramelet A et al. High risk for hyperlipidemia and the metabolic syndrome after an episode of hypertriglyceridemia during 13-cis retinoic acid therapy for acne: A pharmacogenetic study. Ann Intern Med 2002 136 : 582 589.
    • (2002) Ann Intern Med , vol.136 , pp. 582-589
    • Rodondi, N.1    Darioli, R.2    Ramelet, A.3
  • 13
    • 0015374613 scopus 로고
    • Pseudotumor cerebri, psychosis and hypervitaminosis A
    • Restak RM. Pseudotumor cerebri, psychosis and hypervitaminosis A. J Nerv Ment Dis 1972 155 : 72 5.
    • (1972) J Nerv Ment Dis , vol.155 , pp. 72-5
    • Restak, R.M.1
  • 14
    • 0024964494 scopus 로고
    • Depression induced by etretinate
    • Henderson CA, Highet AS. Depression induced by etretinate. BMJ 1989 298 : 964.
    • (1989) BMJ , vol.298 , pp. 964
    • Henderson, C.A.1    Highet, A.S.2
  • 15
    • 12144285316 scopus 로고    scopus 로고
    • Does isotretinoin cause depression and suicide?
    • Bremner JD. Does isotretinoin cause depression and suicide? Psychopharmacol Bull 2003 37 : 64 78.
    • (2003) Psychopharmacol Bull , vol.37 , pp. 64-78
    • Bremner, J.D.1
  • 17
    • 0032488783 scopus 로고    scopus 로고
    • Impaired locomotion and dopamine signaling in retinoid receptor mutant mice
    • Krezel W, Ghyselinck N, Samad TA et al. Impaired locomotion and dopamine signaling in retinoid receptor mutant mice. Science 1998 279 : 863 867.
    • (1998) Science , vol.279 , pp. 863-867
    • Krezel, W.1    Ghyselinck, N.2    Samad, T.A.3
  • 18
    • 21044448352 scopus 로고    scopus 로고
    • Functional brain imaging alterations in acne patients treated with isotretinoin
    • Bremner JD, Fani N, Ashraf A et al. Functional brain imaging alterations in acne patients treated with isotretinoin. Am J Psychiatry 2005 162 : 983 991.
    • (2005) Am J Psychiatry , vol.162 , pp. 983-991
    • Bremner, J.D.1    Fani, N.2    Ashraf, A.3
  • 19
    • 33747360179 scopus 로고    scopus 로고
    • Chronic administration of 13-cis-retinoic acid increases depression-related behavior in mice
    • O'Reilly KC, Shumake J, Gonzalez-Lima F et al. Chronic administration of 13-cis-retinoic acid increases depression-related behavior in mice. Neuropsychopharmacology 2006 31 : 1919 1927.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1919-1927
    • O'Reilly, K.C.1    Shumake, J.2    Gonzalez-Lima, F.3
  • 20
    • 24944558127 scopus 로고    scopus 로고
    • Chronic oral treatment with 13-cis-retinoic acid (isotretinoin) or all-trans-retinoic acid does not alter depression-like behaviors in rats
    • Ferguson SA, Cisneros FJ, Gough B et al. Chronic oral treatment with 13-cis-retinoic acid (isotretinoin) or all-trans-retinoic acid does not alter depression-like behaviors in rats. Toxicol Sci 2005 87 : 451 459.
    • (2005) Toxicol Sci , vol.87 , pp. 451-459
    • Ferguson, S.A.1    Cisneros, F.J.2    Gough, B.3
  • 24
    • 0025810786 scopus 로고
    • Acute depression from isotretinoin
    • Gatti S, Serri F. Acute depression from isotretinoin. J Am Acad Dermatol 1991 25 : 132.
    • (1991) J Am Acad Dermatol , vol.25 , pp. 132
    • Gatti, S.1    Serri, F.2
  • 25
    • 0028858250 scopus 로고
    • Depression associated with isotretinoin therapy
    • Byrne A, Hnatko G. Depression associated with isotretinoin therapy. Can J Psychiatry 1995 40 : 567.
    • (1995) Can J Psychiatry , vol.40 , pp. 567
    • Byrne, A.1    Hnatko, G.2
  • 27
    • 33745676108 scopus 로고    scopus 로고
    • Increased use of mental health services related to isotretinoin treatment: A 5-year analysis
    • Friedman T, Wohl Y, Knobler HY et al. Increased use of mental health services related to isotretinoin treatment: A 5-year analysis. Eur Neuropsychopharmacol 2006 16 : 413 416.
    • (2006) Eur Neuropsychopharmacol , vol.16 , pp. 413-416
    • Friedman, T.1    Wohl, Y.2    Knobler, H.Y.3
  • 28
    • 18544364941 scopus 로고    scopus 로고
    • Isotretinoin therapy and mood changes in adolescents with moderate to severe acne: A cohort study
    • Chia CY, Lane W, Chibnall J et al. Isotretinoin therapy and mood changes in adolescents with moderate to severe acne: A cohort study. Arch Dermatol 2005 141 : 557 560.
    • (2005) Arch Dermatol , vol.141 , pp. 557-560
    • Chia, C.Y.1    Lane, W.2    Chibnall, J.3
  • 30
    • 3342930436 scopus 로고    scopus 로고
    • A pilot study evaluating anxiety and depressive scores in acne patients treated with isotretinoin
    • Ferahbas A, Turan MT, Esel E et al. A pilot study evaluating anxiety and depressive scores in acne patients treated with isotretinoin. J Dermatolog Treat 2004 15 : 153 157.
    • (2004) J Dermatolog Treat , vol.15 , pp. 153-157
    • Ferahbas, A.1    Turan, M.T.2    Esel, E.3
  • 31
    • 34250863402 scopus 로고    scopus 로고
    • No association found between patients receiving isotretinoin for acne and the development of depression in a Canadian prospective cohort
    • Cohen J, Adams S, Patten S. No association found between patients receiving isotretinoin for acne and the development of depression in a Canadian prospective cohort. Can J Clin Pharmacol 2007 14 : 227 233.
    • (2007) Can J Clin Pharmacol , vol.14 , pp. 227-233
    • Cohen, J.1    Adams, S.2    Patten, S.3
  • 32
    • 33846807746 scopus 로고    scopus 로고
    • Incidence of depression related to isotretinoin treatment in 100 acne vulgaris patients
    • Kaymak Y, Kalay M, Ilter N et al. Incidence of depression related to isotretinoin treatment in 100 acne vulgaris patients. Psychol Rep 2006 99 : 897 906.
    • (2006) Psychol Rep , vol.99 , pp. 897-906
    • Kaymak, Y.1    Kalay, M.2    Ilter, N.3
  • 33
    • 0036436821 scopus 로고    scopus 로고
    • Prospective study of depressive symptoms and quality of life in acne vulgaris patients treated with isotretinoin compared to antibiotic and topical therapy
    • Ng CH, Tam MM, Celi E et al. Prospective study of depressive symptoms and quality of life in acne vulgaris patients treated with isotretinoin compared to antibiotic and topical therapy. Australas J Dermatol 2002 43 : 262 268.
    • (2002) Australas J Dermatol , vol.43 , pp. 262-268
    • Ng, C.H.1    Tam, M.M.2    Celi, E.3
  • 34
    • 33745625649 scopus 로고    scopus 로고
    • Isotretinoin and the controversy of psychiatric adverse effects
    • Strahan JE, Raimer S. Isotretinoin and the controversy of psychiatric adverse effects. Int J Dermatol 2006 45 : 789 799.
    • (2006) Int J Dermatol , vol.45 , pp. 789-799
    • Strahan, J.E.1    Raimer, S.2
  • 35
    • 0037766653 scopus 로고    scopus 로고
    • Isotretinoin use and subsequent depression and suicide: Presenting the evidence
    • Hull PR, D'Arcy C. Isotretinoin use and subsequent depression and suicide: Presenting the evidence. Am J Clin Dermatol 2003 4 : 493 505.
    • (2003) Am J Clin Dermatol , vol.4 , pp. 493-505
    • Hull, P.R.1    D'Arcy, C.2
  • 36
    • 23444434537 scopus 로고    scopus 로고
    • Depression and suicidal behavior in acne patients treated with isotretinoin: A systematic review
    • Marqueling AL, Zane LT. Depression and suicidal behavior in acne patients treated with isotretinoin: A systematic review. Semin Cutan Med Surg 2005 24 : 92 102.
    • (2005) Semin Cutan Med Surg , vol.24 , pp. 92-102
    • Marqueling, A.L.1    Zane, L.T.2
  • 37
    • 84894287603 scopus 로고    scopus 로고
    • Medicines and Healthcare Products Regulatory Agency. Available at. last accessed 17 December 2009)
    • Medicines and Healthcare Products Regulatory Agency. Download Drug Analysis Prints (DAPs). Available at : http://www.mhra.gov.uk/Onlineservices/ Medicines/Druganalysisprints/index.htm (last accessed 17 December 2009).
    • Download Drug Analysis Prints (DAPs)
  • 38
    • 0034816150 scopus 로고    scopus 로고
    • An analysis of reports of depression and suicide in patients treated with isotretinoin
    • DOI 10.1067/mjd.2001.117730
    • Wysowski DK, Pitts M, Beitz J. An analysis of reports of depression and suicide in patients treated with isotretinoin. J Am Acad Dermatol 2001 45 : 515 519. (Pubitemid 32917244)
    • (2001) Journal of the American Academy of Dermatology , vol.45 , Issue.4 , pp. 515-519
    • Wysowski, D.K.1    Pitts, M.2    Beitz, J.3
  • 39
    • 0033623285 scopus 로고    scopus 로고
    • Isotretinoin use and risk of depression, psychotic symptoms, suicide and attempted suicide
    • Jick SS, Kremers HM, Vasilakis-Scaramozza C. Isotretinoin use and risk of depression, psychotic symptoms, suicide and attempted suicide. Arch Dermatol 2000 136 : 1231 1236.
    • (2000) Arch Dermatol , vol.136 , pp. 1231-1236
    • Jick, S.S.1    Kremers, H.M.2    Vasilakis-Scaramozza, C.3
  • 40
    • 0032986676 scopus 로고    scopus 로고
    • The psychological and emotional impact of acne and the effect of treatment with isotretinoin
    • Kellett SC, Gawkrodger DJ. The psychological and emotional impact of acne and the effect of treatment with isotretinoin. Br J Dermatol 1999 140 : 273 282.
    • (1999) Br J Dermatol , vol.140 , pp. 273-282
    • Kellett, S.C.1    Gawkrodger, D.J.2
  • 41
    • 0023263529 scopus 로고
    • Reduced anxiety and depression in cystic acne patients after successful treatment with oral isotretinoin
    • Rubinow DR, Peck GL, Squillace KM, Gantt GG. Reduced anxiety and depression in cystic acne patients after successful treatment with oral isotretinoin. J Am Acad Dermatol 1987 17 : 25 32.
    • (1987) J Am Acad Dermatol , vol.17 , pp. 25-32
    • Rubinow, D.R.1    Peck, G.L.2    Squillace, K.M.3    Gantt, G.G.4
  • 42
    • 44849131178 scopus 로고    scopus 로고
    • Isotretinoin and the risk of depression in patients with acne vulgaris: A case-crossover study
    • Azoulay L, Blais L, Koren G et al. Isotretinoin and the risk of depression in patients with acne vulgaris: A case-crossover study. J Clin Psychiatry 2008 69 : 526 532.
    • (2008) J Clin Psychiatry , vol.69 , pp. 526-532
    • Azoulay, L.1    Blais, L.2    Koren, G.3
  • 43
    • 77949656073 scopus 로고    scopus 로고
    • Psychiatric reactions to isotretinoin in patients with bipolar disorder
    • Schaffer LC, Schaffer CB, Hunter S, Miller A. Psychiatric reactions to isotretinoin in patients with bipolar disorder. J Affect Disord 2010 122 : 306 308.
    • (2010) J Affect Disord , vol.122 , pp. 306-308
    • Schaffer, L.C.1    Schaffer, C.B.2    Hunter, S.3    Miller, A.4
  • 44
    • 12144285002 scopus 로고    scopus 로고
    • Affective psychosis following Accutane (isotretinoin) treatment
    • Barak Y, Wohl Y, Greenberg Y et al. Affective psychosis following Accutane (isotretinoin) treatment. Int Clin Psychopharmacol 2005 20 : 39 41.
    • (2005) Int Clin Psychopharmacol , vol.20 , pp. 39-41
    • Barak, Y.1    Wohl, Y.2    Greenberg, Y.3
  • 45
    • 4544357133 scopus 로고    scopus 로고
    • Adverse mood and behaviour change in young patients on systemic isotretinoin
    • Millard LG. Adverse mood and behaviour change in young patients on systemic isotretinoin. Br J Dermatol 1999 141 (Suppl. 55 16.
    • (1999) Br J Dermatol , vol.141 , Issue.SUPPL. 55 , pp. 16
    • Millard, L.G.1
  • 46
    • 0037303674 scopus 로고    scopus 로고
    • The association between depression and isotretinoin use in acne
    • Ng CH, Schweitzer I. The association between depression and isotretinoin use in acne. Aust NZ J Psychiatry 2003 37 : 78 84.
    • (2003) Aust NZ J Psychiatry , vol.37 , pp. 78-84
    • Ng, C.H.1    Schweitzer, I.2
  • 47
    • 0038304522 scopus 로고    scopus 로고
    • Overview of existing research and information linking isotretinoin (Accutane), depression, psychosis, and suicide
    • O'Donnell J. Overview of existing research and information linking isotretinoin (Accutane), depression, psychosis, and suicide. Am J Ther 2003 10 : 148 159.
    • (2003) Am J Ther , vol.10 , pp. 148-159
    • O'Donnell, J.1
  • 48
    • 33746122229 scopus 로고    scopus 로고
    • The British Association of Dermatologists isotretinoin questionnaire for patients: A useful clinical tool
    • McMullen E, Cox NH. The British Association of Dermatologists isotretinoin questionnaire for patients: A useful clinical tool. Clin Exp Dermatol 2006 31 : 713 714.
    • (2006) Clin Exp Dermatol , vol.31 , pp. 713-714
    • McMullen, E.1    Cox, N.H.2
  • 49
    • 0034758740 scopus 로고    scopus 로고
    • Suicide, depression and isotretinoin: Is there a causal link?
    • Jacobs DG, Deutsch NL, Brewer M. Suicide, depression and isotretinoin: is there a causal link? J Am Acad Dermatol 2001 45 : S168 75.
    • (2001) J Am Acad Dermatol , vol.45 , pp. 168-75
    • Jacobs, D.G.1    Deutsch, N.L.2    Brewer, M.3
  • 51
  • 52
    • 0037142885 scopus 로고    scopus 로고
    • Depression in medical patients
    • Peveler R, Carson A, Rodin G. Depression in medical patients. BMJ 2002 325 : 149 152.
    • (2002) BMJ , vol.325 , pp. 149-152
    • Peveler, R.1    Carson, A.2    Rodin, G.3


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