Nucleotide exchange in mitochondria: Insight at a molecular level

Current Opinion in Structural Biology

Volumn 14, Issue 4, 2004, Pages 420-425

  Pebay Peyroula, Eva ^a   Brandolin, Gérard ^b  

^a INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^b Lab Biochim Biophysique Syst I   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE NUCLEOTIDE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; AMINO ACID DERIVATIVE; BACTERIAL PROTEIN; BACTERIORHODOPSIN; CARRIER PROTEIN; FUNGAL PROTEIN; MITOCHONDRIAL DNA; PROLINE DERIVATIVE; PROTEIN DERIVATIVE; TYROSINE DERIVATIVE;

ACCURACY; ALPHA HELIX; BINDING SITE; BIOCHEMISTRY; BIOFILTER; CONFORMATIONAL TRANSITION; CORRELATION ANALYSIS; CRYSTALLIZATION; CYTOSOL; DIMERIZATION; DNA BINDING; GENE TRANSLOCATION; GENETIC ANALYSIS; MEMBRANE BIOLOGY; MITOCHONDRIAL RESPIRATION; MOLECULAR INTERACTION; MOLECULAR MECHANICS; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; OXIDATION KINETICS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN TRANSPORT; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; YEAST;

DIMERIZATION; MITOCHONDRIA; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MODELS, MOLECULAR; NUCLEOTIDES; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 4143120198     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.sbi.2004.06.009     Document Type: Review

References (38)

1. J.E. Walker, and M.J. Runswick The mitochondrial transport protein superfamily J Bioenerg Biomembr 25 1993 435 446
2. F. Palmieri The mitochondrial transporter family (SLC25): physiological and pathological implications Pflugers Arch 447 2004 689 709 A review of current knowledge of the functional properties of mitochondrial carriers and their implication in human diseases.
3. J.E. Walker The mitochondrial transporter family Curr Opin Struct Biol 2 1992 519 526
4. M. Saraste, and J.E. Walker Internal sequence repeats and the path of polypeptide in mitochondrial ADP/ATP translocase FEBS Lett 144 1982 250 254
5. D.R. Nelson, C.M. Felix, and J.M. Swanson Highly conserved charge-pair networks in the mitochondrial carrier family J Mol Biol 277 1998 285 308
6. P. Jezek, and J. Jezek Sequence anatomy of mitochondrial anion carriers FEBS Lett 534 2003 15 25
7. M. Klingenberg Molecular aspects of the adenine nucleotide carrier from mitochondria Arch Biochem Biophys 270 1989 1 14
8. Vignais PV, Block MR, Boulay F, Brandolin G, Lauquin GJ-M: Molecular Aspects of Structure-function Relationships in Mitochondrial Adenine Nucleotide Carrier, vol II, edn G. Bengha: CRC Press; 1985.
9. C. Fiore, V. Trezeguet, A. Le Saux, P. Roux, C. Schwimmer, A.C. Dianoux, F. Noel, G.J. Lauquin, G. Brandolin, and P.V. Vignais The mitochondrial ADP/ATP carrier: structural, physiological and pathological aspects Biochimie 80 1998 137 150
10. T. Gropp, N. Brustovetsky, M. Klingenberg, V. Muller, K. Fendler, and E. Bamberg Kinetics of electrogenic transport by the ADP/ATP carrier Biophys J 77 1999 714 726
11. M.R. Block, G. Zaccai, G.J. Lauquin, and P.V. Vignais Small angle neutron scattering of the mitochondrial ADP/ATP carrier protein in detergent Biochem Biophys Res Commun 109 1982 471 477
12. H. Hackenberg, and M. Klingenberg Molecular weight and hydrodynamic parameters of the adenosine 5′-diphosphate/adenosine 5′-triphosphate carrier in TritonX-100 Biochemistry 19 1980 548 555
13. J. Abramson, I. Smirnova, V. Kasho, G. Verner, H.R. Kaback, and S. Iwata Structure and mechanism of the lactose permease of Escherichia coli Science 301 2003 610 615 On the basis of the crystal structure, the authors propose a mechanism by which lactose permease changes conformation upon ligand binding, therefore inducing the transport mechanism.
14. E. Pebay-Peyroula, C. Dahout-Gonzalez, R. Kahn, V. Trezeguet, G.J. Lauquin, and G. Brandolin Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside Nature 426 2003 39 44 The ADP/ATP carrier is the first member of the MCF for which the structure was solved at high resolution. It reveals a conformation adopted during the transport mechanism and explains the strong inhibition by CATR.
15. C. Dahout-Gonzalez, G. Brandolin, and E. Pebay-Peyroula Crystallization of the bovine ADP/ATP carrier is critically dependent upon the detergent-to-protein ratio Acta Crystallogr D Biol Crystallogr 59 2003 2353 2355 A new approach to crystallizing membrane proteins is described. The authors transposed a classical method for two-dimensional crystallization (elimination of detergent with biobeads in the presence of lipids) to three-dimensional crystallization.
16. D.R. Nelson, J.E. Lawson, M. Klingenberg, and M.G. Douglas Site-directed mutagenesis of the yeast mitochondrial ADP/ATP translocator. Six arginines and one lysine are essential J Mol Biol 230 1993 1159 1170
17. V. Muller, D. Heidkamper, D.R. Nelson, and M. Klingenberg Mutagenesis of some positive and negative residues occurring in repeat triad residues in the ADP/ATP carrier from yeast Biochemistry 36 1997 16008 16018
18. K.A. Denessiouk, and M.S. Johnson When fold is not important: a common structural framework for adenine and AMP binding in 12 unrelated protein families Proteins 38 2000 310 326
19. S.L. Moodie, J.B. Mitchell, and J.M. Thornton Protein recognition of adenylate: an example of a fuzzy recognition template J Mol Biol 263 1996 486 500
20. S. Heimpel, G. Basset, S. Odoy, and M. Klingenberg Expression of the mitochondrial ADP/ATP carrier in Escherichia coli. Renaturation, reconstitution, and the effect of mutations on 10 positive residues J Biol Chem 276 2001 11499 11506
21. V. Trézéguet, A. Le Saux, C. David, C. Gourdet, C. Fiore, A. Dianoux, G. Brandolin, and G.J. Lauquin A covalent tandem dimer of the mitochondrial ADP/ATP carrier is functional in vivo Biochim Biophys Acta 1457 2000 81 93
22. M. Hashimoto, E. Majima, S. Goto, Y. Shinohara, and H. Terada Fluctuation of the first loop facing the matrix of the mitochondrial ADP/ATP carrier deduced from intermolecular cross-linking of Cys56 residues by bifunctional dimaleimides Biochemistry 38 1999 1050 1056
23. Y. Huang, M.J. Lemieux, J. Song, M. Auer, and D.N. Wang Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli Science 301 2003 616 620 The structure of the glycerol-3-phosphate transporter (GlpT) reveals a translocation pore in the center of the protein formed by 12 transmembrane helices. Two arginines implicated in substrate binding are proposed to switch between the two sides of the membrane through helix movements induced by substrate binding.
24. E.R. Kunji, and M. Harding Projection structure of the atractyloside-inhibited mitochondrial ADP/ATP carrier of Saccharomyces cerevisiae J Biol Chem 278 2003 36985 36988
25. A. Harrenga, and H. Michel The cytochrome c oxidase from Paracoccus denitrificans does not change the metal center ligation upon reduction J Biol Chem 274 1999 33296 33299
26. E.R. Kunji The role and structure of mitochondrial carriers FEBS Lett 564 2004 239 244
27. H. Belrhali, P. Nollert, A. Royant, C. Menzel, J.P. Rosenbusch, E.M. Landau, and E. Pebay-Peyroula Protein, lipid and water organization in bacteriorhodopsin crystals: a molecular view of the purple membrane at 1.9 A resolution Structure Fold Des 7 1999 909 917
28. L.O. Essen Halorhodopsin: light-driven ion pumping made simple? Curr Opin Struct Biol 12 2002 516 522
29. A. Royant, P. Nollert, K. Edman, R. Neutze, E.M. Landau, E. Pebay-Peyroula, and J. Navarro X-ray structure of sensory rhodopsin II at 2.1-A resolution Proc Natl Acad Sci USA 98 2001 10131 10136
30. B. Van den Berg, W.M. Clemons Jr., I. Collinson, Y. Modis, E. Hartmann, S.C. Harrison, and T.A. Rapoport X-ray structure of a protein-conducting channel Nature 427 2004 36 44 The SecY structure revealed a constriction formed by hydrophobic residues in the middle of the protein through which a polypeptide can be translocated. The oligomeric state of the functional unit is discussed in light of the structure.
31. I.R. Booth, M.D. Edwards, and S. Miller Bacterial ion channels Biochemistry 42 2003 10045 10053 This paper reviews different classes of ion channels, and discusses ion selectivity, structural changes involved in opening and gating signals in the light of structural data.
32. K.A. Williams, and C.M. Deber Proline residues in transmembrane helices: structural or dynamic role? Biochemistry 30 1991 8919 8923
33. F.S. Cordes, J.N. Bright, and M.S. Sansom Proline-induced distortions of transmembrane helices J Mol Biol 323 2002 951 960
34. S. Subramaniam, and R. Henderson Molecular mechanism of vectorial proton translocation by bacteriorhodopsin Nature 406 2000 653 657
35. T. Okada, and K. Palczewski Crystal structure of rhodopsin: implications for vision and beyond Curr Opin Struct Biol 11 2001 420 426
36. H. Yamaguchi, J.N. Muth, M. Varadi, A. Schwartz, and G. Varadi Critical role of conserved proline residues in the transmembrane segment 4 voltage sensor function and in the gating of L-type calcium channels Proc Natl Acad Sci USA 96 1999 1357 1362
37. Y. Ri, J.A. Ballesteros, C.K. Abrams, S. Oh, V.K. Verselis, H. Weinstein, and T.A. Bargiello The role of a conserved proline residue in mediating conformational changes associated with voltage gating of Cx32 gap junctions Biophys J 76 1999 2887 2898
38. K. Beyer, and B. Nuscher Specific cardiolipin binding interferes with labeling of sulfhydryl residues in the adenosine diphosphate/adenosine triphosphate carrier protein from beef heart mitochondria Biochemistry 35 1996 15784 15790