Hydroxytamoxifen interaction with human erythrocyte membrane and induction of permeabilization and subsequent hemolysis

Toxicology in Vitro

Volumn 15, Issue 6, 2001, Pages 615-622

  Cruz Silva, M M ^a   Madeira, V M C ^b   Almeida, L M ^a,b   Custodio J B A ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

4 Hydroxytamoxifen; Hemolysis; Human erythrocytes; Osmotic swelling; Oxidative stress; Tamoxifen

Indexed keywords

4 HYDROXYTAMOXIFEN; ALPHA TOCOPHEROL; HYDROXYTAMOXIFEN; POTASSIUM ION;

ARTICLE; CELL ISOLATION; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOLYSIS; DRUG EFFECT; EFFUSION; ERYTHROCYTE FRAGILITY; ERYTHROCYTE MEMBRANE; HEMOGLOBIN DETERMINATION; HEMOLYSIS; HEMOLYTIC ANEMIA; HUMAN; HUMAN CELL; INCUBATION TIME; OXIDATION; OXYGEN CONSUMPTION; POTASSIUM CELL LEVEL; POTASSIUM TRANSPORT; PROTEIN BINDING; PROTEIN SECRETION;

ADULT; ALPHA-TOCOPHEROL; CELL MEMBRANE PERMEABILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTE MEMBRANE; HEMOGLOBINS; HEMOLYSIS; HUMANS; MIDDLE AGED; OSMOTIC FRAGILITY; OXIDATIVE STRESS; OXYGEN CONSUMPTION; POTASSIUM; TAMOXIFEN;

EID: 0034754864     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(01)00079-0     Document Type: Article

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