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Volumn 3, Issue 1, 2013, Pages 1-9

Beyond intracranial pressure: Optimization of cerebral blood flow, oxygen, and substrate delivery after traumatic brain injury

Author keywords

Brain oxygen; Cerebral blood flow; Cerebral metabolism; Cerebral microdialysis; Multimodal monitoring; Neuromonitoring; Transcranial doppler; Traumatic brain injury

Indexed keywords

ERYTHROPOIETIN; GLUCOSE; OXYGEN;

EID: 84881263654     PISSN: None     EISSN: 21105820     Source Type: Journal    
DOI: 10.1186/2110-5820-3-23     Document Type: Review
Times cited : (99)

References (75)
  • 2
    • 77952030603 scopus 로고    scopus 로고
    • Relationship of aggressive monitoring and treatment to improved outcomes in severe traumatic brain injury
    • Stein SC, Georgoff P, Meghan S, Mirza KL, El Falaky OM: Relationship of aggressive monitoring and treatment to improved outcomes in severe traumatic brain injury. J Neurosurg 2010, 112:1105-1112.
    • (2010) J Neurosurg , vol.112 , pp. 1105-1112
    • Stein, S.C.1    Georgoff, P.2    Meghan, S.3    Mirza, K.L.4    El Falaky, O.M.5
  • 4
    • 46849094295 scopus 로고    scopus 로고
    • Moderate and severe traumatic brain injury in adults
    • Maas AI, Stocchetti N, Bullock R: Moderate and severe traumatic brain injury in adults. Lancet Neurol 2008, 7:728-741.
    • (2008) Lancet Neurol , vol.7 , pp. 728-741
    • Maas, A.I.1    Stocchetti, N.2    Bullock, R.3
  • 5
    • 0026778284 scopus 로고
    • Blood pressure and intracranial pressure-volume dynamics in severe head injury: Relationship with cerebral blood flow
    • Bouma GJ, Muizelaar JP, Bandoh K, Marmarou A: Blood pressure and intracranial pressure-volume dynamics in severe head injury: relationship with cerebral blood flow. J Neurosurg 1992, 77:15-19.
    • (1992) J Neurosurg , vol.77 , pp. 15-19
    • Bouma, G.J.1    Muizelaar, J.P.2    Bandoh, K.3    Marmarou, A.4
  • 6
    • 77951535289 scopus 로고    scopus 로고
    • Effects of cerebrovascular pressure reactivity-guided optimization of cerebral perfusion pressure on brain tissue oxygenation after traumatic brain injury
    • Jaeger M, Dengl M, Meixensberger J, Schuhmann MU: Effects of cerebrovascular pressure reactivity-guided optimization of cerebral perfusion pressure on brain tissue oxygenation after traumatic brain injury. Crit Care Med 2010, 38:1343-1347.
    • (2010) Crit Care Med , vol.38 , pp. 1343-1347
    • Jaeger, M.1    Dengl, M.2    Meixensberger, J.3    Schuhmann, M.U.4
  • 7
    • 84862176168 scopus 로고    scopus 로고
    • Effect of osmotic agents on regional cerebral blood flow in traumatic brain injury
    • Scalfani MT, Dhar R, Zazulia AR, Videen TO, Diringer MN: Effect of osmotic agents on regional cerebral blood flow in traumatic brain injury. J Crit Care 2012, 27:526. e527-512.
    • (2012) J Crit Care , vol.27 , Issue.526
    • Scalfani, M.T.1    Dhar, R.2    Zazulia, A.R.3    Videen, T.O.4    Diringer, M.N.5
  • 11
    • 34547681749 scopus 로고    scopus 로고
    • Effects of hypervolemia and hypertension on regional cerebral blood flow, intracranial pressure, and brain tissue oxygenation after subarachnoid hemorrhage
    • quiz 1852
    • Muench E, Horn P, Bauhuf C, Roth H, Philipps M, Hermann P, Quintel M, Schmiedek P, Vajkoczy P: Effects of hypervolemia and hypertension on regional cerebral blood flow, intracranial pressure, and brain tissue oxygenation after subarachnoid hemorrhage. Crit Care Med 2007, 35:1844-1851. quiz 1852.
    • (2007) Crit Care Med , vol.35 , pp. 1844-1851
    • Muench, E.1    Horn, P.2    Bauhuf, C.3    Roth, H.4    Philipps, M.5    Hermann, P.6    Quintel, M.7    Schmiedek, P.8    Vajkoczy, P.9
  • 12
    • 78651313600 scopus 로고    scopus 로고
    • Incorporating a parenchymal thermal diffusion cerebral blood flow probe in bedside assessment of cerebral autoregulation and vasoreactivity in patients with severe traumatic brain injury
    • Rosenthal G, Sanchez-Mejia RO, Phan N, Hemphill JC 3rd, Martin C, Manley GT: Incorporating a parenchymal thermal diffusion cerebral blood flow probe in bedside assessment of cerebral autoregulation and vasoreactivity in patients with severe traumatic brain injury. J Neurosurg 2011, 114:62-70.
    • (2011) J Neurosurg , vol.114 , pp. 62-70
    • Rosenthal, G.1    Sanchez-Mejia, R.O.2    Phan, N.3    Hemphill 3rd, J.C.4    Martin, C.5    Manley, G.T.6
  • 14
    • 0030971953 scopus 로고    scopus 로고
    • Ultrastructural study of brain microvessels in patients with traumatic cerebral contusions
    • Vaz R, Sarmento A, Borges N, Cruz C, Azevedo I: Ultrastructural study of brain microvessels in patients with traumatic cerebral contusions. Acta Neurochir (Wien) 1997, 139:215-220.
    • (1997) Acta Neurochir (Wien) , vol.139 , pp. 215-220
    • Vaz, R.1    Sarmento, A.2    Borges, N.3    Cruz, C.4    Azevedo, I.5
  • 15
    • 18144435905 scopus 로고    scopus 로고
    • Morphological features in human cortical brain microvessels after head injury: A three-dimensional and immunocytochemical study
    • Rodriguez-Baeza A, Reina-de la Torre F, Poca A, Marti M, Garnacho A: Morphological features in human cortical brain microvessels after head injury: a three-dimensional and immunocytochemical study. Anat Rec A Discov Mol Cell Evol Biol 2003, 273:583-593.
    • (2003) Anat Rec a Discov Mol Cell Evol Biol , vol.273 , pp. 583-593
    • Rodriguez-Baeza, A.1    de la Reina-Torre, F.2    Poca, A.3    Marti, M.4    Garnacho, A.5
  • 16
    • 76349103537 scopus 로고    scopus 로고
    • Temporal profile of thrombogenesis in the cerebral microcirculation after traumatic brain injury in mice
    • Schwarzmaier SM, Kim SW, Trabold R, Plesnila N: Temporal profile of thrombogenesis in the cerebral microcirculation after traumatic brain injury in mice. J Neurotrauma 2010, 27:121-130.
    • (2010) J Neurotrauma , vol.27 , pp. 121-130
    • Schwarzmaier, S.M.1    Kim, S.W.2    Trabold, R.3    Plesnila, N.4
  • 18
    • 84856460295 scopus 로고    scopus 로고
    • The roles of cerebral blood flow, capillary transit time heterogeneity, and oxygen tension in brain oxygenation and metabolism
    • Jespersen SN, Ostergaard L: The roles of cerebral blood flow, capillary transit time heterogeneity, and oxygen tension in brain oxygenation and metabolism. J Cereb Blood Flow Metab 2012, 32:264-277.
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 264-277
    • Jespersen, S.N.1    Ostergaard, L.2
  • 19
    • 48149104081 scopus 로고    scopus 로고
    • Neuro-Intensive C, Emergency Medicine Section of the European Society of Intensive Care M: NICEM consensus on neurological monitoring in acute neurological disease
    • Andrews PJ, Citerio G, Longhi L, Polderman K, Sahuquillo J, Vajkoczy P, Neuro-Intensive C, Emergency Medicine Section of the European Society of Intensive Care M: NICEM consensus on neurological monitoring in acute neurological disease. Intensive Care Med 2008, 34:1362-1370.
    • (2008) Intensive Care Med , vol.34 , pp. 1362-1370
    • Andrews, P.J.1    Citerio, G.2    Longhi, L.3    Polderman, K.4    Sahuquillo, J.5    Vajkoczy, P.6
  • 22
    • 80053636952 scopus 로고    scopus 로고
    • Brain hypoxia is associated with short-term outcome after severe traumatic brain injury independently of intracranial hypertension and low cerebral perfusion pressure
    • discussion 1045
    • Oddo M, Levine JM, Mackenzie L, Frangos S, Feihl F, Kasner SE, Katsnelson M, Pukenas B, Macmurtrie E, Maloney-Wilensky E, et al: Brain hypoxia is associated with short-term outcome after severe traumatic brain injury independently of intracranial hypertension and low cerebral perfusion pressure. Neurosurgery 2011, 69:1037-1045. discussion 1045.
    • (2011) Neurosurgery , vol.69 , pp. 1037-1045
    • Oddo, M.1    Levine, J.M.2    Mackenzie, L.3    Frangos, S.4    Feihl, F.5    Kasner, S.E.6    Katsnelson, M.7    Pukenas, B.8    Macmurtrie, E.9    Maloney-Wilensky, E.10
  • 23
    • 0028855128 scopus 로고
    • The characteristics of laser-Doppler flowmetry for the measurement of regional cerebral blood flow
    • Fukuda O, Endo S, Kuwayama N, Harada J, Takaku A: The characteristics of laser-Doppler flowmetry for the measurement of regional cerebral blood flow. Neurosurgery 1995, 36:358-364.
    • (1995) Neurosurgery , vol.36 , pp. 358-364
    • Fukuda, O.1    Endo, S.2    Kuwayama, N.3    Harada, J.4    Takaku, A.5
  • 24
    • 77955658957 scopus 로고    scopus 로고
    • Laser-Doppler examination of the blood supply in pericranial flaps
    • Miles B, Davis S, Crandall C, Ellis E 3rd: Laser-Doppler examination of the blood supply in pericranial flaps. J Oral Maxillofac Surg 2010, 68:1740-1745.
    • (2010) J Oral Maxillofac Surg , vol.68 , pp. 1740-1745
    • Miles, B.1    Davis, S.2    Crandall, C.3    Ellis 3rd, E.4
  • 30
    • 33747137966 scopus 로고    scopus 로고
    • Time course of post-traumatic mitochondrial oxidative damage and dysfunction in a mouse model of focal traumatic brain injury: Implications for neuroprotective therapy
    • Singh IN, Sullivan PG, Deng Y, Mbye LH, Hall ED: Time course of post-traumatic mitochondrial oxidative damage and dysfunction in a mouse model of focal traumatic brain injury: implications for neuroprotective therapy. J Cereb Blood Flow Metab 2006, 26:1407-1418.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 1407-1418
    • Singh, I.N.1    Sullivan, P.G.2    Deng, Y.3    Mbye, L.H.4    Hall, E.D.5
  • 32
    • 0033973292 scopus 로고    scopus 로고
    • Intracranial hypertension and cerebral perfusion pressure: Influence on neurological deterioration and outcome in severe head injury. The Executive Committee of the International Selfotel Trial
    • Juul N, Morris GF, Marshall SB, Marshall LF: Intracranial hypertension and cerebral perfusion pressure: influence on neurological deterioration and outcome in severe head injury. The Executive Committee of the International Selfotel Trial. J Neurosurg 2000, 92:1-6.
    • (2000) J Neurosurg , vol.92 , pp. 1-6
    • Juul, N.1    Morris, G.F.2    Marshall, S.B.3    Marshall, L.F.4
  • 34
    • 34547743210 scopus 로고    scopus 로고
    • Guidelines for the management of severe traumatic brain injury. IX. Cerebral perfusion thresholds
    • Brain Trauma F, American Association of Neurological S, Congress of Neurological S, Joint Section on N, Critical Care AC
    • Brain Trauma F, American Association of Neurological S, Congress of Neurological S, Joint Section on N, Critical Care AC, Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, et al: Guidelines for the management of severe traumatic brain injury. IX. Cerebral perfusion thresholds. J Neurotrauma 2007, 24(Suppl 1):S59-S64.
    • (2007) J Neurotrauma , vol.24 , Issue.SUPPL. 1
    • Bratton, S.L.1    Chestnut, R.M.2    Ghajar, J.3    McConnell, H.F.F.4    Harris, O.A.5
  • 35
    • 33744536766 scopus 로고    scopus 로고
    • Continuous assessment of cerebrovascular autoregulation after traumatic brain injury using brain tissue oxygen pressure reactivity
    • Jaeger M, Schuhmann MU, Soehle M, Meixensberger J: Continuous assessment of cerebrovascular autoregulation after traumatic brain injury using brain tissue oxygen pressure reactivity. Crit Care Med 2006, 34:1783-1788.
    • (2006) Crit Care Med , vol.34 , pp. 1783-1788
    • Jaeger, M.1    Schuhmann, M.U.2    Soehle, M.3    Meixensberger, J.4
  • 36
    • 84865716516 scopus 로고    scopus 로고
    • The relationship between cerebral blood flow autoregulation and cerebrovascular pressure reactivity after traumatic brain injury
    • discussion 660-651
    • Budohoski KP, Czosnyka M, de Riva N, Smielewski P, Pickard JD, Menon DK, Kirkpatrick PJ, Lavinio A: The relationship between cerebral blood flow autoregulation and cerebrovascular pressure reactivity after traumatic brain injury. Neurosurgery 2012, 71:652-660. discussion 660-651.
    • (2012) Neurosurgery , vol.71 , pp. 652-660
    • Budohoski, K.P.1    Czosnyka, M.2    de Riva, N.3    Smielewski, P.4    Pickard, J.D.5    Menon, D.K.6    Kirkpatrick, P.J.7    Lavinio, A.8
  • 37
    • 0036213043 scopus 로고    scopus 로고
    • Continuous monitoring of cerebrovascular pressure reactivity allows determination of optimal cerebral perfusion pressure in patients with traumatic brain injury
    • Steiner LA, Czosnyka M, Piechnik SK, Smielewski P, Chatfield D, Menon DK, Pickard JD: Continuous monitoring of cerebrovascular pressure reactivity allows determination of optimal cerebral perfusion pressure in patients with traumatic brain injury. Crit Care Med 2002, 30:733-738.
    • (2002) Crit Care Med , vol.30 , pp. 733-738
    • Steiner, L.A.1    Czosnyka, M.2    Piechnik, S.K.3    Smielewski, P.4    Chatfield, D.5    Menon, D.K.6    Pickard, J.D.7
  • 38
    • 0036784843 scopus 로고    scopus 로고
    • Does tissue oxygen-tension reliably reflect cerebral oxygen delivery and consumption?
    • table of contents
    • Scheufler KM, Rohrborn HJ, Zentner J: Does tissue oxygen-tension reliably reflect cerebral oxygen delivery and consumption? Anesth Analg 2002, 95:1042-1048. table of contents.
    • (2002) Anesth Analg , vol.95 , pp. 1042-1048
    • Scheufler, K.M.1    Rohrborn, H.J.2    Zentner, J.3
  • 39
    • 0032101792 scopus 로고    scopus 로고
    • Correlations between brain tissue oxygen tension, carbon dioxide tension, pH, and cerebral blood flow-a better way of monitoring the severely injured brain?
    • Doppenberg EM, Zauner A, Bullock R, Ward JD, Fatouros PP, Young HF: Correlations between brain tissue oxygen tension, carbon dioxide tension, pH, and cerebral blood flow-a better way of monitoring the severely injured brain? Surg Neurol 1998, 49:650-654.
    • (1998) Surg Neurol , vol.49 , pp. 650-654
    • Doppenberg, E.M.1    Zauner, A.2    Bullock, R.3    Ward, J.D.4    Fatouros, P.P.5    Young, H.F.6
  • 40
    • 29344443755 scopus 로고    scopus 로고
    • Relationship between brain tissue oxygen tension and CT perfusion: Feasibility and initial results
    • Hemphill JC 3rd, Smith WS, Sonne DC, Morabito D, Manley GT: Relationship between brain tissue oxygen tension and CT perfusion: feasibility and initial results. AJNR Am J Neuroradiol 2005, 26:1095-1100.
    • (2005) AJNR Am J Neuroradiol , vol.26 , pp. 1095-1100
    • Hemphill 3rd, J.C.1    Smith, W.S.2    Sonne, D.C.3    Morabito, D.4    Manley, G.T.5
  • 41
    • 45149106869 scopus 로고    scopus 로고
    • Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury
    • Rosenthal G, Hemphill JC 3rd, Sorani M, Martin C, Morabito D, Obrist WD, Manley GT: Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury. Crit Care Med 2008, 36:1917-1924.
    • (2008) Crit Care Med , vol.36 , pp. 1917-1924
    • Rosenthal, G.1    Hemphill 3rd, J.C.2    Sorani, M.3    Martin, C.4    Morabito, D.5    Obrist, W.D.6    Manley, G.T.7
  • 45
    • 0038353624 scopus 로고    scopus 로고
    • Online assessment of brain tissue oxygen autoregulation in traumatic brain injury and subarachnoid hemorrhage
    • Soehle M, Jaeger M, Meixensberger J: Online assessment of brain tissue oxygen autoregulation in traumatic brain injury and subarachnoid hemorrhage. Neurol Res 2003, 25:411-417.
    • (2003) Neurol Res , vol.25 , pp. 411-417
    • Soehle, M.1    Jaeger, M.2    Meixensberger, J.3
  • 46
    • 34547775862 scopus 로고    scopus 로고
    • Guidelines for the management of severe traumatic brain injury. X. Brain oxygen monitoring and thresholds
    • Brain Trauma F, American Association of Neurological S, Congress of Neurological S, Joint Section on N, Critical Care AC
    • Brain Trauma F, American Association of Neurological S, Congress of Neurological S, Joint Section on N, Critical Care AC, Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, et al: Guidelines for the management of severe traumatic brain injury. X. Brain oxygen monitoring and thresholds. J Neurotrauma 2007, 24(Suppl 1):S65-S70.
    • (2007) J Neurotrauma , vol.24 , Issue.SUPPL. 1
    • Bratton, S.L.1    Chestnut, R.M.2    Ghajar, J.3    McConnell Hammond, F.F.4    Harris, O.A.5
  • 47
    • 33947499528 scopus 로고    scopus 로고
    • Transcranial Doppler ultrasound goal-directed therapy for the early management of severe traumatic brain injury
    • Ract C, Le Moigno S, Bruder N, Vigue B: Transcranial Doppler ultrasound goal-directed therapy for the early management of severe traumatic brain injury. Intensive Care Med 2007, 33:645-651.
    • (2007) Intensive Care Med , vol.33 , pp. 645-651
    • Ract, C.1    Le Moigno, S.2    Bruder, N.3    Vigue, B.4
  • 50
    • 77958196711 scopus 로고    scopus 로고
    • Cerebral hemodynamic effects of acute hyperoxia and hyperventilation after severe traumatic brain injury
    • Rangel-Castilla L, Lara LR, Gopinath S, Swank PR, Valadka A, Robertson C: Cerebral hemodynamic effects of acute hyperoxia and hyperventilation after severe traumatic brain injury. J Neurotrauma 2010, 27:1853-1863.
    • (2010) J Neurotrauma , vol.27 , pp. 1853-1863
    • Rangel-Castilla, L.1    Lara, L.R.2    Gopinath, S.3    Swank, P.R.4    Valadka, A.5    Robertson, C.6
  • 52
    • 84865275804 scopus 로고    scopus 로고
    • Brain tissue oxygen monitoring and hyperoxic treatment in patients with traumatic brain injury
    • Beynon C, Kiening KL, Orakcioglu B, Unterberg AW, Sakowitz OW: Brain tissue oxygen monitoring and hyperoxic treatment in patients with traumatic brain injury. J Neurotrauma 2012, 29:2109-2123.
    • (2012) J Neurotrauma , vol.29 , pp. 2109-2123
    • Beynon, C.1    Kiening, K.L.2    Orakcioglu, B.3    Unterberg, A.W.4    Sakowitz, O.W.5
  • 53
    • 78049279683 scopus 로고    scopus 로고
    • Erythropoietin 2nd cerebral protection after acute injuries: A double-edged sword?
    • Velly L, Pellegrini L, Guillet B, Bruder N, Pisano P: Erythropoietin 2nd cerebral protection after acute injuries: a double-edged sword? Pharmacol Ther 2010, 128:445-459.
    • (2010) Pharmacol Ther , vol.128 , pp. 445-459
    • Velly, L.1    Pellegrini, L.2    Guillet, B.3    Bruder, N.4    Pisano, P.5
  • 56
    • 12544249525 scopus 로고    scopus 로고
    • Translational neurochemical research in acute human brain injury: The current status and potential future for cerebral microdialysis
    • Hillered L, Vespa PM, Hovda DA: Translational neurochemical research in acute human brain injury: the current status and potential future for cerebral microdialysis. J Neurotrauma 2005, 22:3-41.
    • (2005) J Neurotrauma , vol.22 , pp. 3-41
    • Hillered, L.1    Vespa, P.M.2    Hovda, D.A.3
  • 59
    • 84858800370 scopus 로고    scopus 로고
    • Brain multimodality monitoring: An update
    • Oddo M, Villa F, Citerio G: Brain multimodality monitoring: an update. Curr Opin Crit Care 2012, 18:111-118.
    • (2012) Curr Opin Crit Care , vol.18 , pp. 111-118
    • Oddo, M.1    Villa, F.2    Citerio, G.3
  • 60
    • 84864839503 scopus 로고    scopus 로고
    • Neuromonitoring after major neurosurgical procedures
    • Messerer M, Daniel RT, Oddo M: Neuromonitoring after major neurosurgical procedures. Minerva Anestesiol 2012, 78:810-822.
    • (2012) Minerva Anestesiol , vol.78 , pp. 810-822
    • Messerer, M.1    Daniel, R.T.2    Oddo, M.3
  • 63
    • 33645318434 scopus 로고    scopus 로고
    • The implications of cerebral ischemia and metabolic dysfunction for treatment strategies in neurointensive care
    • Vespa PM: The implications of cerebral ischemia and metabolic dysfunction for treatment strategies in neurointensive care. Curr Opin Crit Care 2006, 12:119-123.
    • (2006) Curr Opin Crit Care , vol.12 , pp. 119-123
    • Vespa, P.M.1
  • 64
    • 0034981078 scopus 로고    scopus 로고
    • In vivo measurements of brain glucose transport using the reversible Michaelis-Menten model and simultaneous measurements of cerebral blood flow changes during hypoglycemia
    • Choi IY, Lee SP, Kim SG, Gruetter R: In vivo measurements of brain glucose transport using the reversible Michaelis-Menten model and simultaneous measurements of cerebral blood flow changes during hypoglycemia. J Cereb Blood Flow Metab 2001, 21:653-663.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 653-663
    • Choi, I.Y.1    Lee, S.P.2    Kim, S.G.3    Gruetter, R.4
  • 66
  • 67
    • 84861490565 scopus 로고    scopus 로고
    • Relationship between systemic glucose and cerebral glucose is preserved in patients with severe traumatic brain injury, but glucose delivery to the brain may become limited when oxidative metabolism is impaired: Implications for glycemic control
    • Magnoni S, Tedesco C, Carbonara M, Pluderi M, Colombo A, Stocchetti N: Relationship between systemic glucose and cerebral glucose is preserved in patients with severe traumatic brain injury, but glucose delivery to the brain may become limited when oxidative metabolism is impaired: implications for glycemic control. Crit Care Med 2012, 40:1785-1791.
    • (2012) Crit Care Med , vol.40 , pp. 1785-1791
    • Magnoni, S.1    Tedesco, C.2    Carbonara, M.3    Pluderi, M.4    Colombo, A.5    Stocchetti, N.6
  • 70
    • 0031034305 scopus 로고    scopus 로고
    • Brain lactate, not glucose, fuels the recovery of synaptic function from hypoxia upon reoxygenation: An in vitro study
    • Schurr A, Payne RS, Miller JJ, Rigor BM: Brain lactate, not glucose, fuels the recovery of synaptic function from hypoxia upon reoxygenation: an in vitro study. Brain Res 1997, 744:105-111.
    • (1997) Brain Res , vol.744 , pp. 105-111
    • Schurr, A.1    Payne, R.S.2    Miller, J.J.3    Rigor, B.M.4
  • 73
    • 0028082320 scopus 로고
    • Protection by lactate of cerebral function during hypoglycaemia
    • Maran A, Cranston I, Lomas J, Macdonald I, Amiel SA: Protection by lactate of cerebral function during hypoglycaemia. Lancet 1994, 343:16-20.
    • (1994) Lancet , vol.343 , pp. 16-20
    • Maran, A.1    Cranston, I.2    Lomas, J.3    Macdonald, I.4    Amiel, S.A.5
  • 75
    • 60449118292 scopus 로고    scopus 로고
    • Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients
    • Ichai C, Armando G, Orban JC, Berthier F, Rami L, Samat-Long C, Grimaud D, Leverve X: Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients. Intensive Care Med 2009, 35:471-479.
    • (2009) Intensive Care Med , vol.35 , pp. 471-479
    • Ichai, C.1    Armando, G.2    Orban, J.C.3    Berthier, F.4    Rami, L.5    Samat-Long, C.6    Grimaud, D.7    Leverve, X.8


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