메뉴 건너뛰기




Volumn 97, Issue 16, 2013, Pages 7505-7516

Enhanced butanol production in Clostridium acetobutylicum ATCC 824 by double overexpression of 6-phosphofructokinase and pyruvate kinase genes

Author keywords

6 phosphofructokinase; ATP; Clostridium acetobutylicum; NADH; Pyruvate kinase

Indexed keywords

6-PHOSPHOFRUCTOKINASE; CLOSTRIDIUM ACETOBUTYLICUM; CLOSTRIDIUM ACETOBUTYLICUM ATCC 824; ETHANOL CONCENTRATIONS; FED-BATCH FERMENTATION; INTRACELLULAR CONCENTRATION; NADH; PYRUVATE KINASE;

EID: 84881255612     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-013-5075-7     Document Type: Article
Times cited : (75)

References (35)
  • 1
    • 1642324901 scopus 로고    scopus 로고
    • Transcriptional Analysis of spo0A Overexpression in Clostridium acetobutylicum and Its Effect on the Cell's Response to Butanol Stress
    • DOI 10.1128/JB.186.7.1959-1971.2004
    • Alsaker KV, Spitzer TR, Papoutsakis ET (2004) Transcriptional analysis of spo0A overexpression in Clostridium acetobutylicum and its effect on the cell's response to butanol stress. J Bacteriol 186:1959-1971. doi: 10.1128/JB.186.7.1959-1971.2004 (Pubitemid 38381183)
    • (2004) Journal of Bacteriology , vol.186 , Issue.7 , pp. 1959-1971
    • Alsaker, K.V.1    Spitzer, T.R.2    Papoutsakis, E.T.3
  • 2
    • 83055188821 scopus 로고    scopus 로고
    • Metabolome remodeling during the acidogenic-solventogenic transition in Clostridium acetobutylicum
    • 21948824 10.1128/AEM.05374-11 1:CAS:528:DC%2BC3MXhs1GqtrbJ
    • Amador-Noguez D, Brasg IA, Feng X, Roquet N, Rabinowitz JD (2011) Metabolome remodeling during the acidogenic-solventogenic transition in Clostridium acetobutylicum. Appl Environ Microbiol 77:7984-7997
    • (2011) Appl Environ Microbiol , vol.77 , pp. 7984-7997
    • Amador-Noguez, D.1    Brasg, I.A.2    Feng, X.3    Roquet, N.4    Rabinowitz, J.D.5
  • 3
    • 0025760959 scopus 로고
    • Isolation and characterization of Clostridium acetobutylicum mutants with enhanced amylolytic activity
    • 1722664 1:CAS:528:DyaK3MXmtVarur4%3D
    • Annous BA, Blaschek HP (1991) Isolation and characterization of Clostridium acetobutylicum mutants with enhanced amylolytic activity. Appl Environ Microbiol 57:2544-2548
    • (1991) Appl Environ Microbiol , vol.57 , pp. 2544-2548
    • Annous, B.A.1    Blaschek, H.P.2
  • 5
    • 0031802836 scopus 로고    scopus 로고
    • Cloning, sequence, and expression of the phosphofructokinase gene of Clostridium acetobutylicum ATCC 824 in Escherichia coli
    • DOI 10.1007/s002849900330
    • Belouski E, Watson DE, Bennett GN (1998) Cloning, sequence, and expression of the phosphofructokinase gene of Clostridium acetobutylicum ATCC 824 in Escherichia coli. Curr Microbiol 37:17-22 (Pubitemid 28285647)
    • (1998) Current Microbiology , vol.37 , Issue.1 , pp. 17-22
    • Belouski, E.1    Watson, D.E.2    Bennett, G.N.3
  • 6
    • 84869014233 scopus 로고    scopus 로고
    • Targeted mutagenesis of the Clostridium acetobutylicum acetone-butanol-ethanol fermentation pathway
    • 22982601 10.1016/j.ymben.2012.09.001 1:CAS:528:DC%2BC38Xhs1Cjs7rP
    • Cooksley CM, Zhang Y, Wang H, Redl S, Winzer K, Minton NP (2012) Targeted mutagenesis of the Clostridium acetobutylicum acetone-butanol-ethanol fermentation pathway. Metab Eng 14:630-641
    • (2012) Metab Eng , vol.14 , pp. 630-641
    • Cooksley, C.M.1    Zhang, Y.2    Wang, H.3    Redl, S.4    Winzer, K.5    Minton, N.P.6
  • 7
    • 0033156380 scopus 로고    scopus 로고
    • Metabolic Flux Analysis Elucidates the Importance of the Acid-Formation Pathways in Regulating Solvent Production by Clostridium acetobutylicum
    • DOI 10.1006/mben.1999.0118, PII S1096717699901180
    • Desai RP, Harris LM, Welker NE, Papoutsakis ET (1999) Metabolic flux analysis elucidates the Importance of the acid-formation pathways in regulating solvent production by Clostridium acetobutylicum. Metab Eng 1:206-213 (Pubitemid 129499377)
    • (1999) Metabolic Engineering , vol.1 , Issue.3 , pp. 206-213
    • Desai, R.P.1    Harris, L.M.2    Welker, N.E.3    Papoutsakis, E.T.4
  • 8
    • 41349120749 scopus 로고    scopus 로고
    • Fermentative butanol production: Bulk chemical and biofuel
    • DOI 10.1196/annals.1419.009, Incredible Anaerobes From Physiology to Genomics to Fuels
    • Dürre P (2008) Fermentative butanol production bulk chemical and biofuel. Ann NY Acad Sci 1125:353-362. doi: 10.1196/annals.1419.009 (Pubitemid 351451155)
    • (2008) Annals of the New York Academy of Sciences , vol.1125 , pp. 353-362
    • Durre, P.1
  • 9
    • 0022397098 scopus 로고
    • The internal pH of clostridium acetobutylicum and its effect on the shift from acid to solvent formation
    • DOI 10.1007/BF00414766
    • Gottwald M, Gottschalk G (1985) The internal pH of Clostridium acetobutylicum and its effect on the shift from acid to solvent formation. Arch Microbiol 143:42-46 (Pubitemid 16240262)
    • (1985) Archives of Microbiology , vol.143 , Issue.1 , pp. 42-46
    • Gottwald, M.1    Gottschalk, G.2
  • 10
    • 0029846031 scopus 로고    scopus 로고
    • Genetic manipulation of acid formation pathways by gene inactivation in Clostridium acetobutylicum ATCC 824
    • Green EM, Boynton ZL, Harris LM, Rudolph FB, Papoutsakis ET, Bennett GN (1996) Genetic manipulation of acid formation pathways by gene inactivation in Clostridium acetobutylicum ATCC 824. Microbiol 142:2079-2086 (Pubitemid 26288080)
    • (1996) Microbiology , vol.142 , Issue.8 , pp. 2079-2086
    • Green, E.M.1    Boynton, Z.L.2    Harris, L.M.3    Rudolph, F.B.4    Papoutsakis, E.T.5    Bennett, G.N.6
  • 11
    • 0034606690 scopus 로고    scopus 로고
    • Characterization of recombinant strains of the Clostridium acetobutylicum butyrate kinase inactivation mutant: Need for new phenomenological models for solventogenesis and butanol inhibition?
    • DOI 10.1002/(SICI)1097-0290(20000105)67:1<1::AID-BIT1>3.0.CO;2-G
    • Harris LM, Desai RP, Welker NE, Papoutsakis ET (2000) Characterization of recombinant strains of the Clostridium acetobutylicum butyrate kinase inactivation mutant: need for new phenomenological models for solventogenesis and butanol inhibition? Biotechnol Bioeng 67:1-11 (Pubitemid 30029420)
    • (2000) Biotechnology and Bioengineering , vol.67 , Issue.1 , pp. 1-11
    • Harris, L.M.1    Desai, R.P.2    Welker, N.E.3    Papoutsakis, E.T.4
  • 12
    • 0021261020 scopus 로고
    • Intermediary metabolism in Clostridium acetobutylicum: Levels of enzymes involved in the formation of acetate and butyrate
    • Hartmanis MGN, Gatenbeck S (1984) Intermediary metabolism in Clostridium acetobutylicum: levels of enzymes involved in the formation of acetate and butyrate. Appl Environ Microbiol 47:1277-1283 (Pubitemid 14112155)
    • (1984) Applied and Environmental Microbiology , vol.47 , Issue.6 , pp. 1277-1283
    • Hartmanis, M.G.N.1    Gatenbeck, S.2
  • 13
    • 0344363060 scopus 로고
    • Comparison between in vivo and in vitro enzyme activities in continuous and batch fermentations of Clostridium acetobutylicum
    • 10.1007/BF00255364
    • Hüsemann MHW, Papoutsakis ET (1989) Comparison between in vivo and in vitro enzyme activities in continuous and batch fermentations of Clostridium acetobutylicum. Appl Microbiol Biotechnol 30:585-595
    • (1989) Appl Microbiol Biotechnol , vol.30 , pp. 585-595
    • Hüsemann, M.H.W.1    Papoutsakis, E.T.2
  • 14
    • 84868374643 scopus 로고    scopus 로고
    • Enhanced Butanol Production Obtained by Reinforcing the Direct Butanol-Forming Route in Clostridium acetobutylicum
    • 10.1128/mBio.00314-12 10.1128/mBio.00314-12
    • Jang Y, Lee JY, Lee J, Park JH, Im JA, Eom M, Lee J, Lee S, Song H, Cho J (2012) Enhanced Butanol Production Obtained by Reinforcing the Direct Butanol-Forming Route in Clostridium acetobutylicum. mBio 3(5):1-9. doi: 10.1128/mBio.00314-12
    • (2012) MBio , vol.3 , Issue.5 , pp. 1-9
    • Jang, Y.1    Lee, J.Y.2    Lee, J.3    Park, J.H.4    Im, J.A.5    Eom, M.6    Lee, J.7    Lee, S.8    Song, H.9    Cho, J.10
  • 15
    • 0022970603 scopus 로고
    • Acetone-butanol fermentation revisited
    • Jones DT, Woods DR (1986) Acetone-butanol fermentation revisited. Microbiol Rev 50(4):484-524 (Pubitemid 17202900)
    • (1986) Microbiological Reviews , vol.50 , Issue.4 , pp. 484-524
    • Jones, D.T.1    Woods, D.R.2
  • 16
    • 84859950774 scopus 로고    scopus 로고
    • ATP drives direct photosynthetic production of 1-butanol in cyanobacteria
    • 22474341 10.1073/pnas.1200074109 1:CAS:528:DC%2BC38Xmt12mt7k%3D
    • Lan EI, Liao JC (2012) ATP drives direct photosynthetic production of 1-butanol in cyanobacteria. Proc Natl Acad Sci 109:6018-6023
    • (2012) Proc Natl Acad Sci , vol.109 , pp. 6018-6023
    • Lan, E.I.1    Liao, J.C.2
  • 19
    • 80052625837 scopus 로고    scopus 로고
    • Metabolic engineering of Clostridium acetobutylicum: Recent advances to improve butanol production
    • 21377350 10.1016/j.copbio.2011.01.011
    • Lütke-Eversloh T, Bahl H (2011) Metabolic engineering of Clostridium acetobutylicum: recent advances to improve butanol production. Curr Opin Biotechnol 22:634-647
    • (2011) Curr Opin Biotechnol , vol.22 , pp. 634-647
    • Lütke-Eversloh, T.1    Bahl, H.2
  • 20
    • 84872665471 scopus 로고    scopus 로고
    • Thiolase engineering for enhanced butanol production in Clostridium acetobutylicum
    • 23096577 10.1002/bit.24758 1:CAS:528:DC%2BC38XhsF2qsrzN
    • Mann MS, Lütke-Eversloh T (2013) Thiolase engineering for enhanced butanol production in Clostridium acetobutylicum. Biotechnol Bioeng 110:887-897
    • (2013) Biotechnol Bioeng , vol.110 , pp. 887-897
    • Mann, M.S.1    Lütke-Eversloh, T.2
  • 21
    • 84865750105 scopus 로고    scopus 로고
    • Over-expression of stress protein-encoding genes helps Clostridium acetobutylicum to rapidly adapt to butanol stress
    • 22618238 10.1007/s10529-012-0951-2 1:CAS:528:DC%2BC38Xht1OmtbjJ
    • Mann MS, Dragovic Z, Schirrmacher G, Lütke-Eversloh T (2012) Over-expression of stress protein-encoding genes helps Clostridium acetobutylicum to rapidly adapt to butanol stress. Biotechnol Lett 34:1643-1649
    • (2012) Biotechnol Lett , vol.34 , pp. 1643-1649
    • Mann, M.S.1    Dragovic, Z.2    Schirrmacher, G.3    Lütke-Eversloh, T.4
  • 22
    • 77954604280 scopus 로고    scopus 로고
    • Proteome reference map and comparative proteomic analysis between a wild type Clostridium acetobutylicum DSM 1731 and its mutant with enhanced butanol tolerance and butanol yield
    • 20426490 10.1021/pr9012078 1:CAS:528:DC%2BC3cXmtFWisLs%3D
    • Mao S, Luo Y, Zhang T, Li J, Bao G, Zhu Y, Chen Z, Zhang Y, Li Y, Ma Y (2010) Proteome reference map and comparative proteomic analysis between a wild type Clostridium acetobutylicum DSM 1731 and its mutant with enhanced butanol tolerance and butanol yield. J proteome res 9:3046-3061
    • (2010) J Proteome Res , vol.9 , pp. 3046-3061
    • Mao, S.1    Luo, Y.2    Zhang, T.3    Li, J.4    Bao, G.5    Zhu, Y.6    Chen, Z.7    Zhang, Y.8    Li, Y.9    Ma, Y.10
  • 23
    • 0027477171 scopus 로고
    • In vivo methylation in Escherichia coli by the Bacillus subtilis phage φ3T I methyltransferase to protect plasmids from restriction upon transformation of Clostridium acetobutylicum ATCC 824
    • Mermelstein L, Papoutsakis E (1993) In vivo methylation in Escherichia coli by the Bacillus subtilis phage phi 3T I methyltransferase to protect plasmids from restriction upon transformation of Clostridium acetobutylicum ATCC 824. Appl Environ Microbiol 59:1077-1081 (Pubitemid 23096646)
    • (1993) Applied and Environmental Microbiology , vol.59 , Issue.4 , pp. 1077-1081
    • Mermelstein, L.D.1    Papoutsakis, E.T.2
  • 24
    • 0001606699 scopus 로고
    • Increased levels of ATP and NADH are associated with increased solvent production in continuous cultures of Clostridium acetobutylicum
    • 10.1007/BF00263849 1:CAS:528:DyaL1MXktVGru78%3D
    • Meyer CL, Papoutsakis ET (1989) Increased levels of ATP and NADH are associated with increased solvent production in continuous cultures of Clostridium acetobutylicum. Appl Microbiol Biotechnol 30:450-459
    • (1989) Appl Microbiol Biotechnol , vol.30 , pp. 450-459
    • Meyer, C.L.1    Papoutsakis, E.T.2
  • 25
    • 33747333106 scopus 로고
    • Use of dinitrosalicylic acid reagent for determination of reducing sugar
    • 10.1021/ac60147a030 1:CAS:528:DyaG1MXmtFKiuw%3D%3D
    • Miller GL (1959) Use of dinitrosalicylic acid reagent for determination of reducing sugar. Anal Chem 31:426-428
    • (1959) Anal Chem , vol.31 , pp. 426-428
    • Miller, G.L.1
  • 26
    • 0032934363 scopus 로고    scopus 로고
    • Regulation of the sol locus genes for butanol and acetone formation in Clostridium acetobutylicum ATCC 824 by a putative transcriptional repressor
    • Nair RV, Green EM, Watson DE, Bennett GN, Papoutsakis ET (1999) Regulation of the sol locus genes for butanol and acetone formation in Clostridium acetobutylicum ATCC 824 by a putative transcriptional repressor. J Bacteriol 181:319-330 (Pubitemid 29013686)
    • (1999) Journal of Bacteriology , vol.181 , Issue.1 , pp. 319-330
    • Nair, R.V.1    Green, E.M.2    Watson, D.E.3    Bennett, G.N.4    Papoutsakis, E.T.5
  • 27
    • 53049086510 scopus 로고    scopus 로고
    • Engineering solventogenic clostridia
    • 18760360 10.1016/j.copbio.2008.08.003 1:CAS:528:DC%2BD1cXht1SntL7P
    • Papoutsakis ET (2008) Engineering solventogenic clostridia. Curr Opin Biotechnol 19:420-429
    • (2008) Curr Opin Biotechnol , vol.19 , pp. 420-429
    • Papoutsakis, E.T.1
  • 28
    • 0035677893 scopus 로고    scopus 로고
    • Recent advances in ABE fermentation: Hyper-butanol producing Clostridium beijerinckii BA101
    • DOI 10.1038/sj.jim.7000114
    • Qureshi N, Blaschek H (2001) Recent advances in ABE fermentation: hyper-butanol producing Clostridium beijerinckii BA101. J Ind Microbiol Biotechnol 27:287-291 (Pubitemid 34044479)
    • (2001) Journal of Industrial Microbiology and Biotechnology , vol.27 , Issue.5 , pp. 287-291
    • Qureshi, N.1    Blaschek, H.P.2
  • 29
    • 84876397731 scopus 로고    scopus 로고
    • New options to engineer biofuel microbes: Development and application of a high-throughput screening system
    • 23524105 10.1016/j.ymben.2013.03.002 1:CAS:528:DC%2BC3sXmsVGiurY%3D
    • Scheel M, Lütke-Eversloh T (2013) New options to engineer biofuel microbes: development and application of a high-throughput screening system. Metab Eng 17:51-58
    • (2013) Metab Eng , vol.17 , pp. 51-58
    • Scheel, M.1    Lütke-Eversloh, T.2
  • 30
    • 79955611425 scopus 로고    scopus 로고
    • Driving forces enable high-titer anaerobic 1-butanol synthesis in Escherichia coli
    • 21398484 10.1128/AEM.03034-10 1:CAS:528:DC%2BC3MXhtVeju7fO
    • Shen CR, Lan EI, Dekishima Y, Baez A, Cho KM, Liao JC (2011) Driving forces enable high-titer anaerobic 1-butanol synthesis in Escherichia coli. Appl Environ Microbiol 77:2905-2915
    • (2011) Appl Environ Microbiol , vol.77 , pp. 2905-2915
    • Shen, C.R.1    Lan, E.I.2    Dekishima, Y.3    Baez, A.4    Cho, K.M.5    Liao, J.C.6
  • 31
    • 57049169148 scopus 로고    scopus 로고
    • Metabolic engineering of the non-sporulating, non-solventogenic Clostridium acetobutylicum strain M5 to produce butanol without acetone demonstrate the robustness of the acid-formation pathways and the importance of the electron balance
    • 10.1016/j.ymben.2008.07.005 18725313 10.1016/j.ymben.2008.07.005 1:CAS:528:DC%2BD1cXhsVKrt7jN
    • Sillers R, Chow A, Tracy B, Papoutsakis ET (2008) Metabolic engineering of the non-sporulating, non-solventogenic Clostridium acetobutylicum strain M5 to produce butanol without acetone demonstrate the robustness of the acid-formation pathways and the importance of the electron balance. Metab Eng 10:321-332. doi: 10.1016/j.ymben.2008.07.005
    • (2008) Metab Eng , vol.10 , pp. 321-332
    • Sillers, R.1    Chow, A.2    Tracy, B.3    Papoutsakis, E.T.4
  • 32
    • 58149268329 scopus 로고    scopus 로고
    • Aldehyde-alcohol dehydrogenase and/or thiolase overexpression coupled with CoA transferase downregulation lead to higher alcohol titers and selectivity in Clostridium acetobutylicum fermentations
    • 18726959 10.1002/bit.22058 1:CAS:528:DC%2BD1MXitlSj
    • Sillers R, Al-Hinai MA, Papoutsakis ET (2009) Aldehyde-alcohol dehydrogenase and/or thiolase overexpression coupled with CoA transferase downregulation lead to higher alcohol titers and selectivity in Clostridium acetobutylicum fermentations. Biotechnol Bioeng 102:38-49
    • (2009) Biotechnol Bioeng , vol.102 , pp. 38-49
    • Sillers, R.1    Al-Hinai, M.A.2    Papoutsakis, E.T.3
  • 34
    • 0041527249 scopus 로고    scopus 로고
    • Overexpression of groESL in Clostridium acetobutylicum results in increased solvent production and tolerance, prolonged metabolism, and changes in the cell's transcriptional program
    • DOI 10.1128/AEM.69.8.4951-4965.2003
    • Tomas CA, Welker NE, Papoutsakis ET (2003) Overexpression of groESL in Clostridium acetobutylicum results in increased solvent production and tolerance, prolonged metabolism, and changes in the cell's transcriptional program. Appl Environ Microbiol 69:4951-4965. doi: 10.1128/AEM.69.8.4951-4965. 2003 (Pubitemid 36992961)
    • (2003) Applied and Environmental Microbiology , vol.69 , Issue.8 , pp. 4951-4965
    • Tomas, C.A.1    Welker, N.E.2    Papoutsakis, E.T.3
  • 35
    • 84867579077 scopus 로고    scopus 로고
    • The redox-sensing protein Rex, a transcriptional regulator of solventogenesis in Clostridium acetobutylicum
    • 22576944 10.1007/s00253-012-4112-2 1:CAS:528:DC%2BC38XhsVOqsbrI
    • Wietzke M, Bahl H (2012) The redox-sensing protein Rex, a transcriptional regulator of solventogenesis in Clostridium acetobutylicum. Appl Microbiol Biotechnol 96:749-761
    • (2012) Appl Microbiol Biotechnol , vol.96 , pp. 749-761
    • Wietzke, M.1    Bahl, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.