Meal conditions affect the absorption of supplemental vitamin D3 but not the plasma 25-hydroxyvitamin D response to supplementation

Journal of Bone and Mineral Research

Volumn 28, Issue 8, 2013, Pages 1778-1783

  Dawson Hughes, Bess ^a   Harris, Susan S ^a   Palermo, Nancy J ^a   Ceglia, Lisa ^a,b   Rasmussen, Helen ^a  

^a TUFTS UNIVERSITY   (United States)

^b TUFTS MEDICAL CENTER   (United States)

Author keywords

25(OH)D; absorption; dietary fat; meal conditions

Indexed keywords

25 HYDROXYVITAMIN D; CALCIUM; COLECALCIFEROL;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; DRUG ABSORPTION; DRUG RESPONSE; FAT CONTENT; FAT INTAKE; FEMALE; FOOD DRUG INTERACTION; GASTROINTESTINAL ABSORPTION; HUMAN; HUMAN EXPERIMENT; LIPID DIET; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NORMAL HUMAN; OUTCOME ASSESSMENT; RADIOIMMUNOASSAY; RANDOMIZED CONTROLLED TRIAL; VITAMIN BLOOD LEVEL; VITAMIN METABOLISM; VITAMIN SUPPLEMENTATION;

EID: 84881240532     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1896     Document Type: Article

References (22)

1. Lauridsen AL, Vestergaard P, Hermann AP, Brot C, Heickendorff L, Mosekilde L, Nexo E., Plasma concentrations of 25-hydroxy-vitamin D and 1,25-dihydroxy-vitamin D are related to the phenotype of Gc (vitamin D-binding protein): a cross-sectional study on 595 early postmenopausal women. Calcif Tissue Int. 2005; 77 (1): 15-22.
2. Bu FX, Armas L, Lappe J, Zhou Y, Gao G, Wang HW, Recker R, Zhao LJ., Comprehensive association analysis of nine candidate genes with serum 25-hydroxy vitamin D levels among healthy Caucasian subjects. Hum Genet. 2010; 128 (5): 549-56.
3. Fu L, Yun F, Oczak M, Wong BY, Vieth R, Cole DE., Common genetic variants of the vitamin D binding protein (DBP) predict differences in response of serum 25-hydroxyvitamin D [25(OH)D] to vitamin D supplementation. Clin Biochem. 2009; 42 (10-11): 1174-7.
4. Cheng JB, Motola DL, Mangelsdorf DJ, Russell DW., De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxilase. J Biol Chem. 2003; 278 (39): 38084-93.
5. Blum M, Dallal GE, Dawson-Hughes B., Body size and serum 25 hydroxy vitamin D response to oral supplements in healthy older adults. J Am Coll Nutr. 2008; 27 (2): 274-9.
6. Barger-Lux MJ, Heaney RP, Dowell S, Holick MF., Vitamin D and its major metabolites: serum levels after graded oral dosing in healthy men. Osteoporos Int. 1998; 8: 222-30.
7. Hollander D, Muralidhara KS, Zimmerman A., Vitamin D-3 intestinal absorption in vivo: influence of fatty acids, bile salts, and perfusate pH on absorption. Gut. 1978; 19 (4): 267-72.
8. Hollander D., Intestinal absorption of vitamins A, E, D, and K. J Lab Clin Med. 1981; 97 (4): 449-62.
9. Tangpricha V, Koutkia P, Rieke SM, Chen TC, Perez AA, Holick MF., Fortification of orange juice with vitamin D: a novel approach for enhancing vitamin D nutritional health. Am J Clin Nutr. 2003; 77 (6): 1478-83.
10. Mulligan GB, Licata A., Taking vitamin D with the largest meal improves absorption and results in higher serum levels of 25-hydroxyvitamin D. J Bone Miner Res. 2010; 25 (4): 928-30.
11. Raimundo FV, Faulhaber GA, Menegatti PK, Marques Lda S, Furlanetto TW., Effect of high- versus low-fat meal on serum 25-hydroxyvitamin D levels after a single oral dose of vitamin D: a single-blind, parallel, randomized trial. Int J Endocrinol. 2011; 2011: 809069.
12. Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and Calcium [Internet]., Ross AC, Taylor CL, Yaktine AL, Del Valle HB, editors. Dietary Reference Intakes for Calcium and Vitamin D. Washington (DC): National Academies Press (US); 2011. [cited 2013 Feb 19]. Available from:http://www.ncbi.nlm.nih.gov/books/NBK56070/Institute of Medicine.
13. Lo CW, Paris PW, Clemens TL, Nolan J, Holick MF., Vitamin D absorption in healthy subjects and in patients with intestinal malabsorption syndromes. Am J Clin Nutr. 1985; 42 (4): 644-9.
14. Block G, Woods M, Potosky A, Clifford C., Validation of a self-administered diet history questionnaire using multiple diet records. J Clin Epidemiol. 1990; 43 (12): 1327-35.
15. White J, Harris SS, Dallal GE, Dawson-Hughes B., Precision of single vs bilateral hip bone mineral density scans. J Clin Densitom. 2003; 6 (2): 159-62.
16. Rasmussen L, Oster-Jorgensen E, Qvist N, Hovendal CP, Kraglund K, Olsen O, Schaffalitzky de Muckadell OB, Rehfeld J, Pedersen SA., The effects of omeprazole on interdigestive motility and early postprandial levels of gastrin and secretin. Scand J Gastroenterol. 1992; 27 (2): 119-23.
17. Rasmussen L, Qvist N, Oster-Jorgensen E, Rehfeld JF, Holst JJ, Pedersen SA., A double-blind placebo-controlled study on the effects of omeprazole on gut hormone secretion and gastric emptying rate. Scand J Gastroenterol. 1997; 32 (9): 900-5.
18. Samloff IM, Secrist DM, Passaro E Jr., A study of the relationship between serum group I pepsinogen levels and gastric acid secretion. Gastroenterology. 1975; 69 (6): 1196-200.
19. Niramitmahapanya S, Harris SS, Dawson-Hughes B., Type of dietary fat is associated with the 25-hydroxyvitamin D3 increment in response to vitamin D supplementation. J Clin Endocrinol Metab. 2011; 96 (10): 3170-4.
20. Armas LA, Hollis BW, Heaney RP., Vitamin D2 is much less effective than vitamin D3 in humans. J Clin Endocrinol Metab. 2004; 89 (11): 5387-91.
21. Piper DW, Fenton BH., pH stability and activity curves of pepsin with special reference to their clinical importance. Gut. 1965; 6 (5): 506-8.
22. Masclee AA, Jansen JB, Driessen WM, Geuskens LM, Lamers CB., Effect of truncal vagotomy on cholecystokinin release, gallbladder contraction, and gallbladder sensitivity to cholecystokinin in humans. Gastroenterology. 1990; 98 (5 Pt 1): 1338-44.