Molecular mechanisms, thermodynamics, and dissociation kinetics of knob-hole interactions in fibrin

Journal of Biological Chemistry

Volumn 288, Issue 31, 2013, Pages 22681-22692

  Kononova, Olga ^a,b   Litvinov, Rustem I ^c   Zhmurov, Artem ^a,b   Alekseenko, Andrey ^b   Cheng, Chia Ho ^a   Agarwal, Silvi ^a   Marx, Kenneth A ^a   Weisel, John W ^c   Barsegov, Valeri ^a,b  

^a University of Massachusetts Lowell   (United States)

^b MOSCOW INSTITUTE OF PHYSICS AND TECHNOLOGY   (Russian Federation)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTS; DISSOCIATION KINETICS; FIBRIN POLYMERIZATIONS; MOLECULAR MECHANISM; MOLECULAR PICTURES; STRUCTURAL MECHANISMS; THERMODYNAMIC PARAMETER;

DISSOCIATION; SCAFFOLDS; THERMODYNAMICS;

KNOBS;

FIBRIN; FIBRIN DEGRADATION PRODUCT; FIBRINOGEN; GHRP PROTEIN; GPRP PROTEIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION; KNOB HOLE INTERACTION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PH; PRIORITY JOURNAL; PROTEIN POLYMERIZATION; TEMPERATURE; THERMODYNAMICS;

A:A AND B:B KNOB-HOLE BONDS; BIOPHYSICS; DISSOCIATION KINETICS; FIBRIN; FIBRINOGEN; FREE ENERGY LANDSCAPE; MOLECULAR DYNAMICS; PROTEIN-PROTEIN INTERACTIONS;

FIBRIN; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; TEMPERATURE; THERMODYNAMICS;

EID: 84881230813     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.472365     Document Type: Article

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