A Transgenic Tri-Modality Reporter Mouse

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Yan, Xinrui ^a   Ray, Pritha ^b   Paulmurugan, Ramasamy ^a   Tong, Ricky ^a   Gong, Yongquan ^a   Sathirachinda, Ataya ^a   Wu, Joseph C ^a,c   Gambhir, Sanjiv S ^a,c  

^a STANFORD UNIVERSITY   (United States)

^b TATA MEMORIAL HOSPITAL   (India)

^c STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; CELL SURVIVAL; CONTROLLED STUDY; EXPERIMENTAL MODEL; FEMALE; FLUC2 TDTOMATO TTK GENE; FLUORESCENCE IMAGING; FUSION GENE; GENE EXPRESSION REGULATION; HEART INFARCTION; HINDLIMB; IN VIVO STUDY; LASER DOPPLER FLOWMETRY; LIMB ISCHEMIA; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MOLECULAR IMAGING; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROMOTER REGION; REPORTER GENE; TRANSGENIC MOUSE;

EID: 84881229197     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0073580     Document Type: Article

References (37)

1. Yamada S, Terada K, Ueno Y, Sugiyama T, Seno M, et al. (2005) Differentiation of adult hepatic stem-like cells into pancreatic endocrine cells. Cell Transplant 14: 647-653. doi:10.3727/000000005783982738. PubMed: 16405075.
2. De Bari C, Dell'Accio F, Tylzanowski P, Luyten FP, (2001) Multipotent mesenchymal stem cells from adult human synovial membrane. Arthritis Rheum 44: 1928-1942. doi:10.1002/1529-0131(200108)44:8. PubMed: 11508446.
3. Ii M, Nishimura H, Iwakura A, Wecker A, Eaton E, et al. (2005) Endothelial progenitor cells are rapidly recruited to myocardium and mediate protective effect of ischemic preconditioning via "imported" nitric oxide synthase activity. Circulation. 111: 1114-1120. doi:10.1161/01.CIR.0000157144.24888.7E. PubMed: 15723985.
4. Li Z, Wu JC, Sheikh AY, Kraft D, Cao F, et al. (2007) Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. Circulation. 116: I46-I54. PubMed: 17846325.
5. Guzman R, Uchida N, Bliss TM, He D, Christopherson KK, et al. (2007) Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. Proc Natl Acad Sci U S A 104: 10211-10216. doi:10.1073/pnas.0608519104. PubMed: 17553967.
6. Contag CH, Jenkins D, Contag PR, Negrin RS, (2000) Use of reporter genes for optical measurements of neoplastic disease in vivo. Neoplasia. 2: 41-52. doi:10.1038/sj.neo.7900079. PubMed: 10933067.
7. Gambhir SS, Barrio JR, Phelps ME, lyer M, Namavari M,et al (1999) Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography. Proc Natl Acad Sci U S A 96: 2333-2338. doi:10.1073/pnas.96.5.2333. PubMed: 10051642.
8. Massoud TF, Gambhir SS, (2003) Molecular imaging in living subjects: Seeing fundamental biological processes in a new light. Genes Dev 17: 545-580. doi:10.1101/gad.1047403. PubMed: 12629038.
9. Wu JC, Chen IY, Sundaresan G, Min JJ, De A, et al. (2003) Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography. Circulation. 108: 1302-1305. doi:10.1161/01.CIR.0000091252.20010.6E. PubMed: 12963637.
10. Wu JC, Tseng JR, Gambhir SS, (2004) Molecular imaging of cardiovascular gene products. J Nucl Cardiol 11: 491-505. doi:10.1016/j.nuclcard.2004.04.004. PubMed: 15295418.
11. Naldini L, Blömer U, Gallay P, Ory D, Mulligan R, et al. (1996) In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science. 272: 263-267. doi:10.1126/science.272.5259.263. PubMed: 8602510.
12. Cao YA, Wagers AJ, Beilhack A, Dusich J, Bachmann MH, et al. (2004) Shifting foci of hematopoiesis during reconstitution from single stem cells. Proc Natl Acad Sci U S A 101: 221-226. doi:10.1073/pnas.2637010100. PubMed: 14688412.
13. Cao YA, Bachmann MH, Beilhack A, Yang Y, Tanaka M, et al. (2005) Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation. Transplantation. 80: 134-139. doi:10.1097/01.TP.0000164347.50559.A3. PubMed: 16003245.
14. Ray P, Wu AM, Gambhir SS, (2003) Optical bioluminescence and positron emission tomography imaging of a novel fusion reporter gene in tumor xenografts of living mice. Cancer Res 63: 1160-1165. PubMed: 12649169.
15. Ray P, De A, Min JJ, Tsien RY, Gambhir SS, (2004) Imaging tri-fusion multimodality reporter gene expression in living subjects. Cancer Res 64: 1323-1330. doi:10.1158/0008-5472.CAN-03-1816. PubMed: 14973078.
16. Ray P, Tsien R, Gambhir SS, (2007) Construction and validation of improved triple fusion reporter gene vectors for molecular imaging of living subjects. Cancer Res 67: 3085-3093. doi:10.1158/0008-5472.CAN-06-2402. PubMed: 17409415.
17. Gaikwad SM, Gunjal L, Junutula AR, Astanehe A, Gambhir SS, et al. (2013) Non-invasive imaging of Phosphoinositide-3-kinase-catalytic-subunit-alpha (PIK3CA) promoter modulation in small animal models. PLOS ONE. 8(2):: e55971. doi:10.1371/journal.pone.0055971. PubMed: 23393606.
18. Fridenshtein AI, (1982) Stromal bone marrow cells and the hematopoietic microenvironment. Arkh Patol 44: 3-11.
19. Sasaki M, Abe R, Fujita Y, Ando S, Inokuma D, et al. (2008) Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type. J Immunol 180: 2581-2587. PubMed: 18250469.
20. Martens TP, See F, Schuster MD, Sondermeijer HP, Hefti MM, et al. (2006) Mesenchymal lineage precursor cells induce vascular network formation in ischemic myocardium. Nat Clin Pract Cardiovasc Med 3 (Suppl 1) Suppl 1:: S18-S22. doi:10.1038/ncpcardio0404. PubMed: 16501624.
21. Wang H, Cao F, De A, Cao Y, Contag C, et al. (2009) Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging. Stem Cells. 27: 1548-1558. doi:10.1002/stem.81. PubMed: 19544460.
22. Arbab AS, Yocum GT, Kalish H, Jordan EK, Anderson SA, et al. (2004) Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI. Blood. 104: 1217-1223. doi:10.1182/blood-2004-02-0655. PubMed: 15100158.
23. Lee SW, Padmanabhan P, Ray P, Gambhir SS, Doyle T, et al. (2009) Stem cell-mediated accelerated bone healing observed with in vivo molecular and small animal imaging technologies in a model of skeletal injury. J Orthop Res 27: 295-302. doi:10.1002/jor.20736. PubMed: 18752273.
24. Niwa H, Yamamura K, Miyazaki J, (1991) Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene. 108: 193-199. doi:10.1016/0378-1119(91)90434-D. PubMed: 1660837.
25. Yaghoubi SS, Gambhir SS, (2006) Measuring herpes simplex virus thymidine kinase reporter gene expression in vitro. Nat Protoc 1: 2137-2142. doi:10.1038/nprot.2006.334. PubMed: 17487205.
26. Curtis A, Calabro K, Galarneau JR, Bigio IJ, Krucker T, (2011) Temporal variations of skin pigmentation in C57Bl/6 mice affect optical bioluminescence quantitation. Mol Imaging Biol 13(6):: 1114-1123. doi:10.1007/s11307-010-0440-8. PubMed: 20960234.
27. Okabe M, Ikawa M, Kominami K, Nakanishi T, Nishimune Y, (1997) 'Green mice' as a source of ubiquitous green cells. FEBS Lett 407: 313-319. doi:10.1016/S0014-5793(97)00313-X. PubMed: 9175875.
28. Moriya Y, Shibata Y, Abiko Y, Takiguchi H, (1990) [Change of beta-actin gene expression during culture on osteoblast-like cell line, MC3T3-E1]. Nichidai Koko Kagaku. 16: 347-353. PubMed: 2134946.
29. Degrève B, Johansson M, De Clercq E, Karlsson A, Balzarini J, (1998) Differential intracellular compartmentalization of herpetic thymidine kinases (TKs) in TK gene-transfected tumor cells: Molecular characterization of the nuclear localization signal of herpes simplex virus type 1 TK. J Virol 72: 9535-9543. PubMed: 9811686.
30. Cohen JL, Boyer O, Salomon B, Onclerco R, Depetris D, et al. (1998) Fertile homozygous transgenic mice expressing a functional truncated herpes simplex thymidine kinase delta TK gene. Transgenic Res 7: 321-330. doi:10.1023/A:1008893206208. PubMed: 9859221.
31. al-Shawi R, Burke J, Wallace H, Jones C, Harrison S, et al. (1991) The herpes simplex virus type 1 thymidine kinase is expressed in the testes of transgenic mice under the control of a cryptic promoter. Mol Cell Biol 11: 4207-4216. PubMed: 1712906.
32. Yaghoubi SS, Gambhir SS, (2006) PET imaging of herpes simplex virus type 1 thymidine kinase (HSV1-tk) or mutant HSV1-sr39tk reporter gene expression in mice and humans using [18F]FHBG. Nat Protoc 1: 3069-3075. PubMed: 17406570.
33. Yaghoubi SS, Jensen MC, Satyamurthy N, Budhiraja S, Paik D, et al. (2009) Noninvasive detection of therapeutic cytolytic T cells with 18F-FHBG PET in a patient with glioma. Nat Clin Pract Oncol 6(1):: 53-58. doi:10.1038/ncponc1278. PubMed: 19015650.
34. Kraitchman DL, Tatsumi M, Gilson WD, Ishimori T, Kedziorek D, et al. (2005) Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction. Circulation. 112: 1451-1461. doi:10.1161/CIRCULATIONAHA.105.537480. PubMed: 16129797.
35. Deuse T, Stubbendorff M, Tang-Quan K, Phillips N, Kay MA, et al. (2011) Immunogenicity and immunomodulatory properties of umbilical cord lining mesenchymal stem cells. Cell Transplant 20(5):: 655-667. doi:10.3727/096368910X536473. PubMed: 21054940.
36. van der Bogt KE, Sheikh AY, Schrepfer S, Hoyt G, Cao F, et al. (2008) Comparison of different adult stem cell types for treatment of myocardial ischemia. Circulation. 118: S121-S129. doi:10.1161/CIRCULATIONAHA.107.759480. PubMed: 18824743.
37. Swijnenburg RJ, Govaert JA, van der Bogt KE, Pearl JI, Huang M, et al. (2010) Timing of bone marrow cell delivery has minimal effects on cell viability and cardiac recovery following myocardial infarction. Circ Cardiovascular Imaging. 3(1):: 77-85. doi:10.1161/CIRCIMAGING.109.872085.