-
1
-
-
77951568703
-
Phosphoinositide signalling in cancer: beyond PI3K and PTEN
-
Bunney TD, Katan M, (2010) Phosphoinositide signalling in cancer: beyond PI3K and PTEN. Nat Rev Cancer 10: 342-352.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 342-352
-
-
Bunney, T.D.1
Katan, M.2
-
2
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
Vivanco I, Sawyers CL, (2002) The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2: 489-501.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
3
-
-
51849111556
-
PI3K pathway alterations in cancer: variations on a theme
-
Yuan TL, Cantley LC, (2008) PI3K pathway alterations in cancer: variations on a theme. Oncogene 27: 5497-5510.
-
(2008)
Oncogene
, vol.27
, pp. 5497-5510
-
-
Yuan, T.L.1
Cantley, L.C.2
-
4
-
-
28844448182
-
Oncogenic PI3K deregulates transcription and translation
-
Bader AG, Kang S, Zhao L, Vogt PK, (2005) Oncogenic PI3K deregulates transcription and translation. Nat Rev Cancer 5: 921-929.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 921-929
-
-
Bader, A.G.1
Kang, S.2
Zhao, L.3
Vogt, P.K.4
-
6
-
-
20044388328
-
PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas
-
Lee JW, Soung YH, Kim SY, Lee HW, Park WS, et al. (2005) PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene 24: 1477-1480.
-
(2005)
Oncogene
, vol.24
, pp. 1477-1480
-
-
Lee, J.W.1
Soung, Y.H.2
Kim, S.Y.3
Lee, H.W.4
Park, W.S.5
-
7
-
-
66149149812
-
PIK3CA amplification associates with resistance to chemotherapy in ovarian cancer patients
-
Kolasa IK, Rembiszewska A, Felisiak A, Ziolkowska-Seta I, Murawska M, et al. (2009) PIK3CA amplification associates with resistance to chemotherapy in ovarian cancer patients. Cancer Biol Ther 8: 21-26.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 21-26
-
-
Kolasa, I.K.1
Rembiszewska, A.2
Felisiak, A.3
Ziolkowska-Seta, I.4
Murawska, M.5
-
8
-
-
7444250290
-
Mutation of the PIK3CA gene in ovarian and breast cancer
-
Campbell IG, Russell SE, Choong DY, Montgomery KG, Ciavarella ML, et al. (2004) Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res 64: 7678-7681.
-
(2004)
Cancer Res
, vol.64
, pp. 7678-7681
-
-
Campbell, I.G.1
Russell, S.E.2
Choong, D.Y.3
Montgomery, K.G.4
Ciavarella, M.L.5
-
9
-
-
79959838081
-
Integrated genomic analyses of ovarian carcinoma
-
Network TCGA, (2011) Integrated genomic analyses of ovarian carcinoma. Nature 474: 609-615.
-
(2011)
Nature
, vol.474
, pp. 609-615
-
-
Network, T.C.G.A.1
-
10
-
-
73849152723
-
Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein
-
Abedini MR, Muller EJ, Bergeron R, Gray DA, Tsang BK (2009) Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein. Oncogene. 11-25.
-
(2009)
Oncogene
, pp. 11-25
-
-
Abedini, M.R.1
Muller, E.J.2
Bergeron, R.3
Gray, D.A.4
Tsang, B.K.5
-
11
-
-
4344600371
-
Chemoresistance in human ovarian cancer: the role of apoptotic regulators
-
Fraser M, Leung B, Jahani-Asl A, Yan X, Thompson WE, et al. (2003) Chemoresistance in human ovarian cancer: the role of apoptotic regulators. Reprod Biol Endocrinol 1: 66.
-
(2003)
Reprod Biol Endocrinol
, vol.1
, pp. 66
-
-
Fraser, M.1
Leung, B.2
Jahani-Asl, A.3
Yan, X.4
Thompson, W.E.5
-
12
-
-
42149102636
-
Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer
-
Astanehe A, Arenillas D, Wasserman WW, Leung PC, Dunn SE, et al. (2008) Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer. J Cell Sci 121: 664-674.
-
(2008)
J Cell Sci
, vol.121
, pp. 664-674
-
-
Astanehe, A.1
Arenillas, D.2
Wasserman, W.W.3
Leung, P.C.4
Dunn, S.E.5
-
13
-
-
46149106123
-
Transcriptional regulation of PIK3CA oncogene by NF-kappaB in ovarian cancer microenvironment
-
Yang N, Huang J, Greshock J, Liang S, Barchetti A, et al. (2008) Transcriptional regulation of PIK3CA oncogene by NF-kappaB in ovarian cancer microenvironment. PLoS One 3: e1758.
-
(2008)
PLoS One
, vol.3
-
-
Yang, N.1
Huang, J.2
Greshock, J.3
Liang, S.4
Barchetti, A.5
-
14
-
-
0037338436
-
Molecular imaging in living subjects: seeing fundamental biological processes in a new light
-
Massoud TF, Gambhir SS, (2003) Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev 17: 545-580.
-
(2003)
Genes Dev
, vol.17
, pp. 545-580
-
-
Massoud, T.F.1
Gambhir, S.S.2
-
15
-
-
33745253415
-
In vivo bioluminescence imaging of cord blood derived mesenchymal stem cell transplantation into rat myocardium
-
Min JJ, Ahn Y, Moon S, Kim YS, Park JE, et al. (2006) In vivo bioluminescence imaging of cord blood derived mesenchymal stem cell transplantation into rat myocardium. Ann Nucl Med 20: 165-170.
-
(2006)
Ann Nucl Med
, vol.20
, pp. 165-170
-
-
Min, J.J.1
Ahn, Y.2
Moon, S.3
Kim, Y.S.4
Park, J.E.5
-
16
-
-
0034753231
-
Monitoring gene therapy with reporter gene imaging
-
Ray P, Bauer E, Iyer M, Barrio JR, Satyamurthy N,et al. (2001) Monitoring gene therapy with reporter gene imaging. Semin Nucl Med 31: 312-320.
-
(2001)
Semin Nucl Med
, vol.31
, pp. 312-320
-
-
Ray, P.1
Bauer, E.2
Iyer, M.3
Barrio, J.R.4
Satyamurthy, N.5
-
17
-
-
9244250387
-
Multimodality in vivo molecular-genetic imaging
-
Doubrovin M, Serganova I, Mayer-Kuckuk P, Ponomarev V, Blasberg RG, (2004) Multimodality in vivo molecular-genetic imaging. Bioconjug Chem 15: 1376-1388.
-
(2004)
Bioconjug Chem
, vol.15
, pp. 1376-1388
-
-
Doubrovin, M.1
Serganova, I.2
Mayer-Kuckuk, P.3
Ponomarev, V.4
Blasberg, R.G.5
-
18
-
-
2942741151
-
Role of reporter gene imaging in molecular and cellular biology
-
Mayer-Kuckuk P, Menon LG, Blasberg RG, Bertino JR, Banerjee D, (2004) Role of reporter gene imaging in molecular and cellular biology. Biol Chem 385: 353-361.
-
(2004)
Biol Chem
, vol.385
, pp. 353-361
-
-
Mayer-Kuckuk, P.1
Menon, L.G.2
Blasberg, R.G.3
Bertino, J.R.4
Banerjee, D.5
-
19
-
-
53249155162
-
Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects
-
Ray P, De A, Patel M, Gambhir SS, (2008) Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects. Clin Cancer Res 14: 5801-5809.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5801-5809
-
-
Ray, P.1
De, A.2
Patel, M.3
Gambhir, S.S.4
-
20
-
-
34248169598
-
Construction and validation of improved triple fusion reporter gene vectors for molecular imaging of living subjects
-
Ray P, Tsien R, Gambhir SS, (2007) Construction and validation of improved triple fusion reporter gene vectors for molecular imaging of living subjects. Cancer Res 67: 3085-3093.
-
(2007)
Cancer Res
, vol.67
, pp. 3085-3093
-
-
Ray, P.1
Tsien, R.2
Gambhir, S.S.3
-
21
-
-
0037444158
-
Optical bioluminescence and positron emission tomography imaging of a novel fusion reporter gene in tumor xenografts of living mice
-
Ray P, Wu AM, Gambhir SS, (2003) Optical bioluminescence and positron emission tomography imaging of a novel fusion reporter gene in tumor xenografts of living mice. Cancer Res 63: 1160-1165.
-
(2003)
Cancer Res
, vol.63
, pp. 1160-1165
-
-
Ray, P.1
Wu, A.M.2
Gambhir, S.S.3
-
22
-
-
33645079671
-
In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery
-
Cao F, Lin S, Xie X, Ray P, Patel M, et al. (2006) In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. Circulation 113: 1005-1014.
-
(2006)
Circulation
, vol.113
, pp. 1005-1014
-
-
Cao, F.1
Lin, S.2
Xie, X.3
Ray, P.4
Patel, M.5
-
23
-
-
28444432657
-
Visualization of a primary anti-tumor immune response by positron emission tomography
-
Shu CJ, Guo S, Kim YJ, Shelly SM, Nijagal A, et al. (2005) Visualization of a primary anti-tumor immune response by positron emission tomography. Witte ONProc Natl Acad Sci U S A 102(48): 17412-17417.
-
(2005)
Witte ONProc Natl Acad Sci U S A
, vol.102
, Issue.48
, pp. 17412-17417
-
-
Shu, C.J.1
Guo, S.2
Kim, Y.J.3
Shelly, S.M.4
Nijagal, A.5
-
24
-
-
37549025341
-
Multimodality imaging of T-cell hybridoma trafficking in collagen-induced arthritic mice: image-based estimation of the number of cells accumulating in mouse paws
-
Yaghoubi SS, Creusot RJ, Ray P, Fathman CG, Gambhir SS, (2007) Multimodality imaging of T-cell hybridoma trafficking in collagen-induced arthritic mice: image-based estimation of the number of cells accumulating in mouse paws. J Biomed Opt 12: 064025.
-
(2007)
J Biomed Opt
, vol.12
, pp. 064025
-
-
Yaghoubi, S.S.1
Creusot, R.J.2
Ray, P.3
Fathman, C.G.4
Gambhir, S.S.5
-
25
-
-
77955640606
-
Fluorescent proteins and their applications in imaging living cells and tissues
-
Chudakov DM, Matz MV, Lukyanov S, Lukyanov KA, (2010) Fluorescent proteins and their applications in imaging living cells and tissues. Physiol Rev 90: 1103-1163.
-
(2010)
Physiol Rev
, vol.90
, pp. 1103-1163
-
-
Chudakov, D.M.1
Matz, M.V.2
Lukyanov, S.3
Lukyanov, K.A.4
-
26
-
-
77951985351
-
Illuminating plant biology: using fluorescent proteins for high-throughput analysis of protein localization and function in plants
-
DeBlasio SL, Sylvester AW, Jackson D, (2010) Illuminating plant biology: using fluorescent proteins for high-throughput analysis of protein localization and function in plants. Brief Funct Genomics 9: 129-138.
-
(2010)
Brief Funct Genomics
, vol.9
, pp. 129-138
-
-
DeBlasio, S.L.1
Sylvester, A.W.2
Jackson, D.3
-
27
-
-
0037418882
-
Development and use of fluorescent protein markers in living cells
-
Lippincott-Schwartz J, Patterson GH, (2003) Development and use of fluorescent protein markers in living cells. Science 300: 87-91.
-
(2003)
Science
, vol.300
, pp. 87-91
-
-
Lippincott-Schwartz, J.1
Patterson, G.H.2
-
28
-
-
1242338786
-
Imaging tri-fusion multimodality reporter gene expression in living subjects
-
Ray P, De A, Min JJ, Tsien RY, Gambhir SS, (2004) Imaging tri-fusion multimodality reporter gene expression in living subjects. Cancer Res 64: 1323-1330.
-
(2004)
Cancer Res
, vol.64
, pp. 1323-1330
-
-
Ray, P.1
De, A.2
Min, J.J.3
Tsien, R.Y.4
Gambhir, S.S.5
-
29
-
-
44449109239
-
Improving the photostability of bright monomeric orange and red fluorescent proteins
-
Shaner NC, Lin MZ, McKeown MR, Steinbach PA, Hazelwood KL, et al. (2008) Improving the photostability of bright monomeric orange and red fluorescent proteins. Nat Methods 5: 545-551.
-
(2008)
Nat Methods
, vol.5
, pp. 545-551
-
-
Shaner, N.C.1
Lin, M.Z.2
McKeown, M.R.3
Steinbach, P.A.4
Hazelwood, K.L.5
-
30
-
-
0345256652
-
Cisplatin: mode of cytotoxic action and molecular basis of resistance
-
Siddik ZH, (2003) Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 22: 7265-7279.
-
(2003)
Oncogene
, vol.22
, pp. 7265-7279
-
-
Siddik, Z.H.1
-
31
-
-
0032776201
-
Paclitaxel sensitivity correlates with p53 status and DNA fragmentation, but not G2/M accumulation
-
Rakovitch E, Mellado W, Hall EJ, Pandita TK, Sawant S, et al. (1999) Paclitaxel sensitivity correlates with p53 status and DNA fragmentation, but not G2/M accumulation. Int J Radiat Oncol Biol Phys 44: 1119-1124.
-
(1999)
Int J Radiat Oncol Biol Phys
, vol.44
, pp. 1119-1124
-
-
Rakovitch, E.1
Mellado, W.2
Hall, E.J.3
Pandita, T.K.4
Sawant, S.5
-
32
-
-
79953792757
-
Cisplatin -induced Toxicological Effects in Relation to the Endogenous Tissue Glutathione Level in Tumor-Bearing Mice
-
Prasad SB, Rosangkima G, Khyynriam D, (2006) Cisplatin-induced Toxicological Effects in Relation to the Endogenous Tissue Glutathione Level in Tumor-Bearing Mice. Asian J Exp Sci, Vol 20: 55-68.
-
(2006)
Asian J Exp Sci, Vol
, vol.20
, pp. 55-68
-
-
Prasad, S.B.1
Rosangkima, G.2
Khyynriam, D.3
-
33
-
-
0043240182
-
Ovarian cancer: strategies for overcoming resistance to chemotherapy
-
Agarwal R, Kaye SB, (2003) Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat Rev Cancer 3: 502-516.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 502-516
-
-
Agarwal, R.1
Kaye, S.B.2
-
34
-
-
33846872771
-
Reporter gene imaging of protein-protein interactions in living subjects
-
Massoud TF, Paulmurugan R, De A, Ray P, Gambhir SS, (2007) Reporter gene imaging of protein-protein interactions in living subjects. Curr Opin Biotechnol 18: 31-37.
-
(2007)
Curr Opin Biotechnol
, vol.18
, pp. 31-37
-
-
Massoud, T.F.1
Paulmurugan, R.2
De, A.3
Ray, P.4
Gambhir, S.S.5
-
35
-
-
33749844245
-
Noninvasive optical tracking of red fluorescent protein-expressing cancer cells in a model of metastatic breast cancer
-
Winnard PT Jr, Kluth JB, Raman V, (2006) Noninvasive optical tracking of red fluorescent protein-expressing cancer cells in a model of metastatic breast cancer. Neoplasia 8: 796-806.
-
(2006)
Neoplasia
, vol.8
, pp. 796-806
-
-
Winnard Jr., P.T.1
Kluth, J.B.2
Raman, V.3
-
36
-
-
0035963277
-
Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity
-
Giannakakou P, Robey R, Fojo T, Blagosklonny MV, (2001) Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity. Oncogene 20: 3806-3813.
-
(2001)
Oncogene
, vol.20
, pp. 3806-3813
-
-
Giannakakou, P.1
Robey, R.2
Fojo, T.3
Blagosklonny, M.V.4
|