Acetic acid inhibits nutrient uptake in Saccharomyces cerevisiae: Auxotrophy confounds the use of yeast deletion libraries for strain improvement

Applied Microbiology and Biotechnology

Volumn 97, Issue 16, 2013, Pages 7405-7416

  Ding, Jun ^a   Bierma, Jan ^a   Smith, Mark R ^a   Poliner, Eric ^b   Wolfe, Carole ^b   Hadduck, Alex N ^a   Zara, Severino ^c   Jirikovic, Mallori ^a   Van Zee, Kari ^a   Penner, Michael H ^a   Patton Vogt, Jana ^b   Bakalinsky, Alan T ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b DUQUESNE UNIVERSITY   (United States)

^c UNIVERSITY OF SASSARI   (Italy)

Author keywords

Acetic acid; ATP; Auxotrophy; Endocytosis; Nutrient uptake; Saccharomyces cerevisiae; Yeast deletion library

Indexed keywords

ACETIC ACID TREATMENT; AUXOTROPHY; ENDOCYTOSIS; FACILITATED DIFFUSIONS; GLUCOSE TRANSPORTERS; NUTRIENT UPTAKE; POTENTIAL INTERFERENCES; SACCHAROMYCES CEREVISIAE STRAINS;

ACETIC ACID; ACID RESISTANCE; ADENOSINETRIPHOSPHATE; AMINO ACIDS; ENCODING (SYMBOLS); GENE EXPRESSION; GLUCOSE; LIBRARIES; MOLECULAR BIOLOGY; NUTRIENTS; PH;

YEAST;

ACETIC ACID; ADENOSINE TRIPHOSPHATE; GLUCOSE; GLUCOSE TRANSPORTER; HISTIDINE; LEUCINE; LYSINE; PHOSPHATE; PROTON; TRYPTOPHAN; URACIL;

ACETIC ACID; FERMENTATION; GLUCOSE; NUTRIENT UPTAKE; PH; STRAIN; YEAST;

ARTICLE; AUXOTROPHY; CONTROLLED STUDY; DIFFUSION; GENE MUTATION; GROWTH INHIBITION; NONHUMAN; NUTRIENT; NUTRIENT UPTAKE; PH; SACCHAROMYCES CEREVISIAE; STRAIN IMPROVEMENT; YEAST;

ACETIC ACID; AMINO ACIDS; FERMENTATION; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; GLUCOSE; MEMBRANE TRANSPORT PROTEINS; PHOSPHATES; SACCHAROMYCES CEREVISIAE; URACIL;

SACCHAROMYCES CEREVISIAE;

EID: 84881220384     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-013-5071-y     Document Type: Article

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