-
2
-
-
78951496001
-
Variants in MHC, LCE and IL12B have epistatic effects on psoriasis risk in Chinese population
-
Zheng HF, Zuo XB, Lu WS, et al. Variants in MHC, LCE and IL12B have epistatic effects on psoriasis risk in Chinese population. J Dermatol Sci 2011; 61: 124-128.
-
(2011)
J Dermatol Sci
, vol.61
, pp. 124-128
-
-
Zheng, H.F.1
Zuo, X.B.2
Lu, W.S.3
-
3
-
-
45349094509
-
IFN-regulatory factor 5 gene variants interact with the class i MHC locus in the Swedish psoriasis population
-
Sanchez FO, Linga Reddy MV, Mallbris L, Sakuraba K, Stahle M, Alarcon-Riquelme ME,. IFN-regulatory factor 5 gene variants interact with the class I MHC locus in the Swedish psoriasis population. J Invest Dermatol. 2008; 128: 1704-1709.
-
(2008)
J Invest Dermatol.
, vol.128
, pp. 1704-1709
-
-
Sanchez, F.O.1
Linga Reddy, M.V.2
Mallbris, L.3
Sakuraba, K.4
Stahle, M.5
Alarcon-Riquelme, M.E.6
-
4
-
-
79959664445
-
HLA-C, CSTA and DS12346 susceptibility alleles confer over 100-fold increased risk of developing psoriasis: Evidence of gene interaction
-
Vasilopoulos Y, Sagoo GS, Cork MJ, Walters K, Tazi-Ahnini R,. HLA-C, CSTA and DS12346 susceptibility alleles confer over 100-fold increased risk of developing psoriasis: evidence of gene interaction. J Hum Genet 2011; 56: 423-427.
-
(2011)
J Hum Genet
, vol.56
, pp. 423-427
-
-
Vasilopoulos, Y.1
Sagoo, G.S.2
Cork, M.J.3
Walters, K.4
Tazi-Ahnini, R.5
-
5
-
-
59149106117
-
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways
-
Nair RP, Duffin KC, Helms C, et al. Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet 2009; 41: 199-204.
-
(2009)
Nat Genet
, vol.41
, pp. 199-204
-
-
Nair, R.P.1
Duffin, K.C.2
Helms, C.3
-
6
-
-
78049347495
-
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
-
Strange A, Capon F, Spencer CC, et al. A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet 2010; 42: 985-990.
-
(2010)
Nat Genet
, vol.42
, pp. 985-990
-
-
Strange, A.1
Capon, F.2
Spencer, C.C.3
-
7
-
-
78049343768
-
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
-
Ellinghaus E, Ellinghaus D, Stuart PE, et al. Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. Nat Genet 2010; 42: 991-995.
-
(2010)
Nat Genet
, vol.42
, pp. 991-995
-
-
Ellinghaus, E.1
Ellinghaus, D.2
Stuart, P.E.3
-
8
-
-
48249089671
-
Association analysis of the skin barrier gene cystatin A at the PSORS5 locus in psoriatic patients: Evidence for interaction between PSORS1 and PSORS5
-
Vasilopoulos Y, Walters K, Cork MJ, Duff GW, Sagoo GS, Tazi-Ahnini R,. Association analysis of the skin barrier gene cystatin A at the PSORS5 locus in psoriatic patients: evidence for interaction between PSORS1 and PSORS5. Eur J Hum Genet 2008; 16: 1002-1009.
-
(2008)
Eur J Hum Genet
, vol.16
, pp. 1002-1009
-
-
Vasilopoulos, Y.1
Walters, K.2
Cork, M.J.3
Duff, G.W.4
Sagoo, G.S.5
Tazi-Ahnini, R.6
-
9
-
-
33646417072
-
The IL-23/IL-17 axis in inflammation
-
Iwakura Y, Ishigame H,. The IL-23/IL-17 axis in inflammation. J Clin Invest 2006; 116: 1218-1222.
-
(2006)
J Clin Invest
, vol.116
, pp. 1218-1222
-
-
Iwakura, Y.1
Ishigame, H.2
-
10
-
-
77449161010
-
Genetic evidence for involvement of the IL23 pathway in Thai psoriatics
-
Nair RP, Stuart PE, Kullavanijaya P, Tejasvi T, Voorhees JJ, Elder JT,. Genetic evidence for involvement of the IL23 pathway in Thai psoriatics. Arch Dermatol Res 2010; 302: 139-143.
-
(2010)
Arch Dermatol Res
, vol.302
, pp. 139-143
-
-
Nair, R.P.1
Stuart, P.E.2
Kullavanijaya, P.3
Tejasvi, T.4
Voorhees, J.J.5
Elder, J.T.6
-
11
-
-
67650255063
-
Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease
-
McGovern DP, Rotter JI, Mei L, et al. Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease. Inflamm Bowel Dis 2009; 15: 883-889.
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 883-889
-
-
McGovern, D.P.1
Rotter, J.I.2
Mei, L.3
-
12
-
-
78049329814
-
Association analyses identify six new psoriasis susceptibility loci in the Chinese population
-
Sun LD, Cheng H, Wang ZX, et al. Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet 2010; 42: 1005-1009.
-
(2010)
Nat Genet
, vol.42
, pp. 1005-1009
-
-
Sun, L.D.1
Cheng, H.2
Wang, Z.X.3
-
13
-
-
37349131221
-
Pathophysiology of psoriasis: Recent advances on IL-23 and Th17 cytokines
-
Fitch E, Harper E, Skorcheva I, Kurtz SE, Blauvelt A,. Pathophysiology of psoriasis: recent advances on IL-23 and Th17 cytokines. Curr Rheumatol Rep 2007; 9: 461-467.
-
(2007)
Curr Rheumatol Rep
, vol.9
, pp. 461-467
-
-
Fitch, E.1
Harper, E.2
Skorcheva, I.3
Kurtz, S.E.4
Blauvelt, A.5
-
14
-
-
59149096149
-
Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21
-
Zhang XJ, Huang W, Yang S, et al. Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. Nat Genet 2009; 41: 205-210.
-
(2009)
Nat Genet
, vol.41
, pp. 205-210
-
-
Zhang, X.J.1
Huang, W.2
Yang, S.3
-
15
-
-
0034973569
-
Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer
-
Ritchie MD, Hahn LW, Roodi N, et al. Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am J Hum Genet 2001; 69: 138-147.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 138-147
-
-
Ritchie, M.D.1
Hahn, L.W.2
Roodi, N.3
-
16
-
-
34247338434
-
A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction
-
Velez DR, White BC, Motsinger AA, et al. A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction. Genet Epidemiol 2007; 31: 306-315.
-
(2007)
Genet Epidemiol
, vol.31
, pp. 306-315
-
-
Velez, D.R.1
White, B.C.2
Motsinger, A.A.3
-
17
-
-
67349166946
-
Detecting gene-gene interactions that underlie human diseases
-
Cordell HJ,. Detecting gene-gene interactions that underlie human diseases. Nat Rev Genet 2009; 10: 392-404.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 392-404
-
-
Cordell, H.J.1
-
18
-
-
58549093348
-
Genetic variants of the IL-23R pathway: Association with psoriatic arthritis and psoriasis vulgaris, but no specific risk factor for arthritis
-
Huffmeier U, Lascorz J, Bohm B, et al. Genetic variants of the IL-23R pathway: association with psoriatic arthritis and psoriasis vulgaris, but no specific risk factor for arthritis. J Invest Dermatol 2009; 129: 355-358.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 355-358
-
-
Huffmeier, U.1
Lascorz, J.2
Bohm, B.3
-
19
-
-
57349093812
-
Investigation of association of the IL12B and IL23R genes with psoriatic arthritis
-
Filer C, Ho P, Smith RL, et al. Investigation of association of the IL12B and IL23R genes with psoriatic arthritis. Arthritis Rheum 2008; 58: 3705-3709.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3705-3709
-
-
Filer, C.1
Ho, P.2
Smith, R.L.3
-
20
-
-
33846608131
-
A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes
-
Cargill M, Schrodi SJ, Chang M, et al. A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet 2007; 80: 273-290.
-
(2007)
Am J Hum Genet
, vol.80
, pp. 273-290
-
-
Cargill, M.1
Schrodi, S.J.2
Chang, M.3
-
21
-
-
77951094127
-
Molecular dissection of psoriasis: Integrating genetics and biology
-
Elder JT, Bruce AT, Gudjonsson JE, et al. Molecular dissection of psoriasis: integrating genetics and biology. J Invest Dermatol 2010; 130: 1213-1226.
-
(2010)
J Invest Dermatol
, vol.130
, pp. 1213-1226
-
-
Elder, J.T.1
Bruce, A.T.2
Gudjonsson, J.E.3
-
22
-
-
77956404314
-
TNF, but not IL-6 and IL-17, is crucial for the development of T cell-independent psoriasis-like dermatitis in Il1rn-/- mice
-
Nakajima A, Matsuki T, Komine M, et al. TNF, but not IL-6 and IL-17, is crucial for the development of T cell-independent psoriasis-like dermatitis in Il1rn-/- mice. J Immunol 2010; 185: 1887-1893.
-
(2010)
J Immunol
, vol.185
, pp. 1887-1893
-
-
Nakajima, A.1
Matsuki, T.2
Komine, M.3
-
23
-
-
34247343295
-
Cytokine gene polymorphisms in Chinese patients with psoriasis
-
Chang YT, Chou CT, Yu CW, et al. Cytokine gene polymorphisms in Chinese patients with psoriasis. Br J Dermatol 2007; 156: 899-905.
-
(2007)
Br J Dermatol
, vol.156
, pp. 899-905
-
-
Chang, Y.T.1
Chou, C.T.2
Yu, C.W.3
-
24
-
-
34447512939
-
TNF polymorphisms in psoriasis: Association of psoriatic arthritis with the promoter polymorphism TNF-857 independent of the PSORS1 risk allele
-
Reich K, Huffmeier U, Konig IR, et al. TNF polymorphisms in psoriasis: association of psoriatic arthritis with the promoter polymorphism TNF-857 independent of the PSORS1 risk allele. Arthritis Rheum 2007; 56: 2056-2064.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2056-2064
-
-
Reich, K.1
Huffmeier, U.2
Konig, I.R.3
-
25
-
-
54149088214
-
Epistasis - The essential role of gene interactions in the structure and evolution of genetic systems
-
Phillips PC,. Epistasis - the essential role of gene interactions in the structure and evolution of genetic systems. Nat Rev Genet 2008; 9: 855-867.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 855-867
-
-
Phillips, P.C.1
-
26
-
-
79955533725
-
Tumor necrosis factor alpha inhibitors as immunomodulatory antirejection agents after intestinal transplantation
-
Gerlach UA, Koch M, Muller HP, Veltzke-Schlieker W, Neuhaus P, Pascher A,. Tumor necrosis factor alpha inhibitors as immunomodulatory antirejection agents after intestinal transplantation. Am J Transplant 2011; 11: 1041-1050.
-
(2011)
Am J Transplant
, vol.11
, pp. 1041-1050
-
-
Gerlach, U.A.1
Koch, M.2
Muller, H.P.3
Veltzke-Schlieker, W.4
Neuhaus, P.5
Pascher, A.6
-
27
-
-
79958044361
-
Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21
-
Hughes T, Kim-Howard X, Kelly JA, et al. Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21. Arthritis Rheum 2011; 63: 1689-1697.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1689-1697
-
-
Hughes, T.1
Kim-Howard, X.2
Kelly, J.A.3
-
28
-
-
77957714732
-
Clinical disease caused by Klebsiella in 2 unrelated patients with interleukin 12 receptor beta1 deficiency
-
Pedraza S, Lezana JL, Samarina A, et al. Clinical disease caused by Klebsiella in 2 unrelated patients with interleukin 12 receptor beta1 deficiency. Pediatrics 2010; 126: e971-976.
-
(2010)
Pediatrics
, vol.126
-
-
Pedraza, S.1
Lezana, J.L.2
Samarina, A.3
-
29
-
-
80855152742
-
Proinflammatory cytokines in peritonitis
-
Badiu DC, Paunescu V, Aungurenci A, Pasarica D,. Proinflammatory cytokines in peritonitis. J Med Life 2011; 4: 158-162.
-
(2011)
J Med Life
, vol.4
, pp. 158-162
-
-
Badiu, D.C.1
Paunescu, V.2
Aungurenci, A.3
Pasarica, D.4
-
30
-
-
77952783111
-
Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients
-
Vijayanand P, Durkin K, Hartmann G, et al. Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients. J Immunol 2010; 184: 4568-4574.
-
(2010)
J Immunol
, vol.184
, pp. 4568-4574
-
-
Vijayanand, P.1
Durkin, K.2
Hartmann, G.3
-
31
-
-
36849036211
-
IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner
-
Wei L, Laurence A, Elias KM, O'Shea JJ,. IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner. J Biol Chem 2007; 282: 34605-34610.
-
(2007)
J Biol Chem
, vol.282
, pp. 34605-34610
-
-
Wei, L.1
Laurence, A.2
Elias, K.M.3
O'Shea, J.J.4
-
32
-
-
40749156754
-
Identification of cellular pathways of 'type 1,' Th17 T cells, and TNF- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis
-
Haider AS, Lowes MA, Suarez-Farinas M, et al. Identification of cellular pathways of 'type 1,' Th17 T cells, and TNF- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis. J Immunol 2008; 180: 1913-1920.
-
(2008)
J Immunol
, vol.180
, pp. 1913-1920
-
-
Haider, A.S.1
Lowes, M.A.2
Suarez-Farinas, M.3
-
33
-
-
34547188748
-
IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou L, Ivanov II, Spolski R, et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 2007; 8: 967-974.
-
(2007)
Nat Immunol
, vol.8
, pp. 967-974
-
-
Zhou, L.1
Ivanov, I.I.2
Spolski, R.3
-
34
-
-
69449095507
-
IL-17-producing CD8 + T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines
-
Ortega C, Fernandez AS, Carrillo JM, et al. IL-17-producing CD8 + T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines. J Leukoc Biol 2009; 86: 435-443.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 435-443
-
-
Ortega, C.1
Fernandez, A.S.2
Carrillo, J.M.3
-
35
-
-
77958469463
-
Detecting, characterizing, and interpreting nonlinear gene-gene interactions using multifactor dimensionality reduction
-
Moore JH,. Detecting, characterizing, and interpreting nonlinear gene-gene interactions using multifactor dimensionality reduction. Adv Genet 2010; 72: 101-116.
-
(2010)
Adv Genet
, vol.72
, pp. 101-116
-
-
Moore, J.H.1
|