The iodide-transport-defect-causing mutation R124H: A δ-amino group at position 124 is critical for maturation and trafficking of the Na+/I- symporter

Journal of Cell Science

Volumn 126, Issue 15, 2013, Pages 3305-3313

  Paroder, Viktoriya ^a,c   Nicola, Juan P ^b   Ginter, Christopher S ^a,d   Carrasco, Nancy ^a,b  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MONTEFIORE MEDICAL CENTER   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Congenital iodide transport defect; Impaired intracellular trafficking; Membrane vesicles; Na+ I symporter (NIS); Plasma membrane targeting

Indexed keywords

IODIDE; SODIUM IODIDE SYMPORTER;

AMINO ACID SUBSTITUTION; ARTICLE; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; MEMBRANE VESICLE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; VIBRIO PARAHAEMOLYTICUS;

CONGENITAL IODIDE TRANSPORT DEFECT; IMPAIRED INTRACELLULAR TRAFFICKING; MEMBRANE VESICLES; NA+/I- SYMPORTER (NIS); PLASMA MEMBRANE TARGETING;

AMINO ACID SEQUENCE; ANIMALS; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; DOGS; HUMANS; IODIDES; MADIN DARBY CANINE KIDNEY CELLS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN FOLDING; PROTEIN TRANSPORT; STRUCTURE-ACTIVITY RELATIONSHIP; SYMPORTERS; TRANSFECTION;

EID: 84881157295     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.120246     Document Type: Article

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