The Q267E mutation in the sodium/iodide symporter (NIS) causes congenital iodide transport defect (ITD) by decreasing the NIS turnover number

Journal of Cell Science

Volumn 117, Issue 5, 2004, Pages 677-687

  De la Vieja, Antonio ^a   Ginter, Christopher S ^a   Carrasco, Nancy ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

ITD (iodide transport defect); Membrane proteins; NIS (sodium iodide symporter); Thyroid

Indexed keywords

COMPLEMENTARY DNA; MUTANT PROTEIN; SODIUM IODIDE SYMPORTER;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CATALYSIS; CELL STRAIN COS7; CONGENITAL HYPOTHYROIDISM; CONTROLLED STUDY; DNA ISOLATION; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; GENETIC CODE; GENETIC TRANSFECTION; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; WILD TYPE;

ALANINE; AMINO ACID SUBSTITUTION; ANIMALS; ASPARAGINE; BIOLOGICAL TRANSPORT; BIOTINYLATION; CELL LINE; CELL MEMBRANE; COS CELLS; GLUTAMIC ACID; GLUTAMINE; HUMANS; IODIDES; KINETICS; MUTATION, MISSENSE; SODIUM; SYMPORTERS; THYROID GLAND;

ANIMALIA; COMOCLADIA GLABRA;

EID: 1342305177     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.00898     Document Type: Article

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