메뉴 건너뛰기




Volumn 12, Issue 8, 2013, Pages 3801-3808

Enhanced green fluorescent protein transgenic expression in vivo is not biologically inert

Author keywords

3 ureidopropionate; EGFP; metabolism; metabonomics; transgene

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN;

EID: 84881135750     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr400567g     Document Type: Article
Times cited : (13)

References (48)
  • 2
    • 0035316371 scopus 로고    scopus 로고
    • A GFP-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse
    • Krestel, H. E.; Mayford, M. R.; Seeburg, P. H.; Sprengel, R. A GFP-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse Nucleic Acids Res. 2001, 29 (7) e39
    • (2001) Nucleic Acids Res. , vol.29 , Issue.7 , pp. 39
    • Krestel, H.E.1    Mayford, M.R.2    Seeburg, P.H.3    Sprengel, R.4
  • 5
    • 84865203983 scopus 로고    scopus 로고
    • A restricted cell population propagates glioblastoma growth after chemotherapy
    • Chen, J.; Li, Y. J.; Yu, T. S.; McKay, R. M.; Burns, D. K.; Kernie, S. G.; Parada, L. F. A restricted cell population propagates glioblastoma growth after chemotherapy Nature 2012, 488 (7412) 522
    • (2012) Nature , vol.488 , Issue.7412 , pp. 522
    • Chen, J.1    Li, Y.J.2    Yu, T.S.3    McKay, R.M.4    Burns, D.K.5    Kernie, S.G.6    Parada, L.F.7
  • 6
    • 0031663369 scopus 로고    scopus 로고
    • The green fluorescent protein
    • Tsien, R. Y. The green fluorescent protein Annu. Rev. Biochem. 1998, 67, 509-544
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 509-544
    • Tsien, R.Y.1
  • 7
    • 0028580734 scopus 로고
    • Wavelength mutations and posttranslational autoxidation of green fluorescent protein
    • Heim, R.; Prasher, D. C.; Tsien, R. Y. Wavelength mutations and posttranslational autoxidation of green fluorescent protein Proc. Natl. Acad. Sci. U.S.A. 1994, 91 (26) 12501-12504
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , Issue.26 , pp. 12501-12504
    • Heim, R.1    Prasher, D.C.2    Tsien, R.Y.3
  • 8
    • 5144222230 scopus 로고    scopus 로고
    • Neuronal co-expression of EGFP and β-galactosidase in mice causes neuropathology and premature death
    • Krestel, H. E.; Mihaljevic, A. L. A.; Hoffman, D. A.; Schneider, A. Neuronal co-expression of EGFP and β-galactosidase in mice causes neuropathology and premature death Neurobiol. Dis. 2004, 17 (2) 310-318
    • (2004) Neurobiol. Dis. , vol.17 , Issue.2 , pp. 310-318
    • Krestel, H.E.1    Mihaljevic, A.L.A.2    Hoffman, D.A.3    Schneider, A.4
  • 9
    • 0037367289 scopus 로고    scopus 로고
    • Adenoviral transduction of mouse hematopoietic stem cells
    • Bradfute, S. B.; Goodell, M. A. Adenoviral transduction of mouse hematopoietic stem cells Mol. Ther. 2003, 7 (3) 334-340
    • (2003) Mol. Ther. , vol.7 , Issue.3 , pp. 334-340
    • Bradfute, S.B.1    Goodell, M.A.2
  • 10
    • 2142808842 scopus 로고    scopus 로고
    • Intermingling versus clonal coherence during skeletal muscle development: Mosaicism in eGFP/nLacZ-labeled mouse chimeras
    • Eberhard, D.; Jockusch, H. Intermingling versus clonal coherence during skeletal muscle development: mosaicism in eGFP/nLacZ-labeled mouse chimeras Dev. Dyn. 2004, 230 (1) 69-78
    • (2004) Dev. Dyn. , vol.230 , Issue.1 , pp. 69-78
    • Eberhard, D.1    Jockusch, H.2
  • 11
    • 79951576930 scopus 로고    scopus 로고
    • The effect of excess expression of GFP in a novel heart-specific green fluorescence zebrafish regulated by nppa enhancer at early embryonic development
    • Huang, W.; Deng, Y.; Dong, W.; Yuan, W. Z.; Wan, Y. Q.; Mo, X. Y.; Li, Y. Q.; Wang, Z. Q.; Wang, Y. Q.; Ocorr, K.; Zhang, B.; Lin, S.; Wu, X. S. The effect of excess expression of GFP in a novel heart-specific green fluorescence zebrafish regulated by nppa enhancer at early embryonic development Mol. Biol. Rep. 2011, 38 (2) 793-799
    • (2011) Mol. Biol. Rep. , vol.38 , Issue.2 , pp. 793-799
    • Huang, W.1    Deng, Y.2    Dong, W.3    Yuan, W.Z.4    Wan, Y.Q.5    Mo, X.Y.6    Li, Y.Q.7    Wang, Z.Q.8    Wang, Y.Q.9    Ocorr, K.10    Zhang, B.11    Lin, S.12    Wu, X.S.13
  • 12
    • 0034106175 scopus 로고    scopus 로고
    • Transgenic expression of green fluorescence protein can cause dilated cardiomyopathy
    • Huang, W. Y.; Aramburu, J.; Douglas, P. S.; Izumo, S. Transgenic expression of green fluorescence protein can cause dilated cardiomyopathy Nat. Med. 2000, 6 (5) 482-483
    • (2000) Nat. Med. , vol.6 , Issue.5 , pp. 482-483
    • Huang, W.Y.1    Aramburu, J.2    Douglas, P.S.3    Izumo, S.4
  • 13
    • 0032812877 scopus 로고    scopus 로고
    • Immune response to green fluorescent protein: Implications for gene therapy
    • Stripecke, R.; Villacres, M. D.; Skelton, D. C.; Satake, N.; Halene, S.; Kohn, D. B. Immune response to green fluorescent protein: implications for gene therapy Gene Ther. 1999, 6 (7) 1305-1312
    • (1999) Gene Ther. , vol.6 , Issue.7 , pp. 1305-1312
    • Stripecke, R.1    Villacres, M.D.2    Skelton, D.C.3    Satake, N.4    Halene, S.5    Kohn, D.B.6
  • 14
    • 0032694577 scopus 로고    scopus 로고
    • 'Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
    • Nicholson, J. K.; Lindon, J. C.; Holmes, E. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data Xenobiotica 1999, 29 (11) 1181-1189
    • (1999) Xenobiotica , vol.29 , Issue.11 , pp. 1181-1189
    • Nicholson, J.K.1    Lindon, J.C.2    Holmes, E.3
  • 15
    • 33746309537 scopus 로고    scopus 로고
    • Metabonomics: A revolution in progress
    • Tang, H. R.; Wang, Y. L. Metabonomics: a revolution in progress Prog. Biochem. Biophys. 2006, 33 (5) 401-417
    • (2006) Prog. Biochem. Biophys. , vol.33 , Issue.5 , pp. 401-417
    • Tang, H.R.1    Wang, Y.L.2
  • 16
    • 0036083139 scopus 로고    scopus 로고
    • Orthogonal projections to latent structures (O-PLS)
    • Trygg, J.; Wold, S. Orthogonal projections to latent structures (O-PLS) J. Chemom. 2002, 16 (3) 119-128
    • (2002) J. Chemom. , vol.16 , Issue.3 , pp. 119-128
    • Trygg, J.1    Wold, S.2
  • 17
    • 0034775361 scopus 로고    scopus 로고
    • NMR and pattern recognition studies on the time-related metabolic effects of α-naphthylisothiocyanate on liver, urine, and plasma in the rat: An integrative metabonomic approach
    • Waters, N. J.; Holmes, E.; Williams, A.; Waterfield, C. J.; Farrant, R. D.; Nicholson, J. K. NMR and pattern recognition studies on the time-related metabolic effects of α-naphthylisothiocyanate on liver, urine, and plasma in the rat: an integrative metabonomic approach Chem. Res. Toxicol. 2001, 14 (10) 1401-1412
    • (2001) Chem. Res. Toxicol. , vol.14 , Issue.10 , pp. 1401-1412
    • Waters, N.J.1    Holmes, E.2    Williams, A.3    Waterfield, C.J.4    Farrant, R.D.5    Nicholson, J.K.6
  • 18
    • 80655138713 scopus 로고    scopus 로고
    • Dynamic metabolic response of mice to acute mequindox exposure
    • Zhao, X. J.; Huang, C. Y.; Lei, H. H.; Nie, X.; Tang, H. R.; Wang, Y. L. Dynamic metabolic response of mice to acute mequindox exposure J. Proteome Res. 2011, 10 (11) 5183-5190
    • (2011) J. Proteome Res. , vol.10 , Issue.11 , pp. 5183-5190
    • Zhao, X.J.1    Huang, C.Y.2    Lei, H.H.3    Nie, X.4    Tang, H.R.5    Wang, Y.L.6
  • 19
    • 0035107971 scopus 로고    scopus 로고
    • Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks
    • Holmes, E.; Nicholson, J. K.; Tranter, G. Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks Chem. Res. Toxicol. 2001, 14 (2) 182-191
    • (2001) Chem. Res. Toxicol. , vol.14 , Issue.2 , pp. 182-191
    • Holmes, E.1    Nicholson, J.K.2    Tranter, G.3
  • 21
    • 3042750616 scopus 로고    scopus 로고
    • Integration of transcriptomics and metabolomics for understanding of global responses to nutritional stresses in Arabidopsis thaliana
    • Hirai, M. Y.; Yano, M.; Goodenowe, D. B.; Kanaya, S.; Kimura, T.; Awazuhara, M.; Arita, M.; Fujiwara, T.; Saito, K. Integration of transcriptomics and metabolomics for understanding of global responses to nutritional stresses in Arabidopsis thaliana Proc. Natl. Acad. Sci. U.S.A. 2004, 101 (27) 10205-10210
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , Issue.27 , pp. 10205-10210
    • Hirai, M.Y.1    Yano, M.2    Goodenowe, D.B.3    Kanaya, S.4    Kimura, T.5    Awazuhara, M.6    Arita, M.7    Fujiwara, T.8    Saito, K.9
  • 22
    • 12344311533 scopus 로고    scopus 로고
    • A metabonomic strategy for the detection of the metabolic effects of chamomile (Matricaria recutita L.) ingestion
    • Wang, Y. L.; Tang, H. R.; Nicholson, J. K.; Hylands, P. J.; Sampson, J.; Holmes, E. A metabonomic strategy for the detection of the metabolic effects of chamomile (Matricaria recutita L.) ingestion J. Agric. Food. Chem. 2005, 53 (2) 191-196
    • (2005) J. Agric. Food. Chem. , vol.53 , Issue.2 , pp. 191-196
    • Wang, Y.L.1    Tang, H.R.2    Nicholson, J.K.3    Hylands, P.J.4    Sampson, J.5    Holmes, E.6
  • 27
    • 84866123760 scopus 로고    scopus 로고
    • Systems responses of rats to mequindox revealed by metabolic and transcriptomic profiling
    • Zhao, X. J.; Hao, F. H.; Huang, C. Y.; Rantalainen, M.; Lei, H. H.; Tang, H. R.; Wang, Y. L. Systems responses of rats to mequindox revealed by metabolic and transcriptomic profiling J. Proteome Res. 2012, 11 (9) 4712-4721
    • (2012) J. Proteome Res. , vol.11 , Issue.9 , pp. 4712-4721
    • Zhao, X.J.1    Hao, F.H.2    Huang, C.Y.3    Rantalainen, M.4    Lei, H.H.5    Tang, H.R.6    Wang, Y.L.7
  • 28
    • 65349128823 scopus 로고    scopus 로고
    • An optimized buffer system for NMR-based urinary metabonomics with effective pH control, chemical shift consistency and dilution minimization
    • Xiao, C.; Hao, F.; Qin, X.; Wang, Y.; Tang, H. An optimized buffer system for NMR-based urinary metabonomics with effective pH control, chemical shift consistency and dilution minimization Analyst 2009, 134 (5) 916-25
    • (2009) Analyst , vol.134 , Issue.5 , pp. 916-925
    • Xiao, C.1    Hao, F.2    Qin, X.3    Wang, Y.4    Tang, H.5
  • 29
    • 77949803652 scopus 로고    scopus 로고
    • Combined NMR and LC-DAD-MS analysis reveals comprehensive metabonomic variations for three phenotypic cultivars of salvia miltiorrhiza bunge
    • Dai, H.; Xiao, C. N.; Liu, H. B.; Hao, F. H.; Tang, H. R. Combined NMR and LC-DAD-MS analysis reveals comprehensive metabonomic variations for three phenotypic cultivars of salvia miltiorrhiza bunge J. Proteome Res. 2010, 9 (3) 1565-1578
    • (2010) J. Proteome Res. , vol.9 , Issue.3 , pp. 1565-1578
    • Dai, H.1    Xiao, C.N.2    Liu, H.B.3    Hao, F.H.4    Tang, H.R.5
  • 30
    • 57149116166 scopus 로고    scopus 로고
    • CV-ANOVA for significance testing of PLS and OPLS (R) models
    • Eriksson, L.; Trygg, J.; Wold, S. CV-ANOVA for significance testing of PLS and OPLS (R) models J. Chemom. 2008, 22 (11-12) 594-600
    • (2008) J. Chemom. , vol.22 , Issue.1112 , pp. 594-600
    • Eriksson, L.1    Trygg, J.2    Wold, S.3
  • 32
    • 38749110011 scopus 로고    scopus 로고
    • Structure-based profiling of metabolites and isotopomers by NMR
    • Fan, T. W. M.; Lane, A. N. Structure-based profiling of metabolites and isotopomers by NMR Prog. Nucl. Magn. Reson. Spectrosc. 2008, 52 (2-3) 69-117
    • (2008) Prog. Nucl. Magn. Reson. Spectrosc. , vol.52 , Issue.23 , pp. 69-117
    • Fan, T.W.M.1    Lane, A.N.2
  • 34
    • 75749140577 scopus 로고    scopus 로고
    • Bidirectional correlation of NMR and capillary electrophoresis fingerprints: A new approach to investigating Schistosoma mansoni infection in a mouse model
    • Garcia-Perez, I.; Alves, A. C.; Angulo, S.; Li, J. V.; Utzinger, J.; Ebbels, T. M. D.; Legido-Quigley, C.; Nicholson, J. K.; Holmes, E.; Barbas, C. Bidirectional correlation of NMR and capillary electrophoresis fingerprints: a new approach to investigating Schistosoma mansoni infection in a mouse model Anal. Chem. 2010, 82 (1) 203-210
    • (2010) Anal. Chem. , vol.82 , Issue.1 , pp. 203-210
    • Garcia-Perez, I.1    Alves, A.C.2    Angulo, S.3    Li, J.V.4    Utzinger, J.5    Ebbels, T.M.D.6    Legido-Quigley, C.7    Nicholson, J.K.8    Holmes, E.9    Barbas, C.10
  • 36
    • 0013936167 scopus 로고
    • Codon-anticodon pairing:The wobble hypothesis
    • Crick, F. H. C. Codon-anticodon pairing:The wobble hypothesis J. Mol. Biol. 1966, 19 (2) 548-555
    • (1966) J. Mol. Biol. , vol.19 , Issue.2 , pp. 548-555
    • Crick, F.H.C.1
  • 37
    • 0034232357 scopus 로고    scopus 로고
    • The G center dot U wobble base pair - A fundamental building block of RNA structure crucial to RNA function in diverse biological systems
    • Varani, G.; McClain, W. H. The G center dot U wobble base pair-A fundamental building block of RNA structure crucial to RNA function in diverse biological systems EMBO Rep. 2000, 1 (1) 18-23
    • (2000) EMBO Rep. , vol.1 , Issue.1 , pp. 18-23
    • Varani, G.1    McClain, W.H.2
  • 41
    • 0035704168 scopus 로고    scopus 로고
    • The enhanced green fluorescent protein (eGFP) is minimally immunogenic in C57BL/6 mice
    • Skelton, D.; Satake, N.; Kohn, D. B. The enhanced green fluorescent protein (eGFP) is minimally immunogenic in C57BL/6 mice Gene Ther. 2001, 8 (23) 1813-1814
    • (2001) Gene Ther. , vol.8 , Issue.23 , pp. 1813-1814
    • Skelton, D.1    Satake, N.2    Kohn, D.B.3
  • 42
    • 0015806204 scopus 로고
    • Pyruvate-kinase-classes of regulatory isoenzymes in mammalian tissues
    • Carbonel., J.; Feliu, J. E.; Marco, R.; Sols, A. Pyruvate-kinase-classes of regulatory isoenzymes in mammalian tissues Eur. J. Biochem. 1973, 37 (1) 148-156
    • (1973) Eur. J. Biochem. , vol.37 , Issue.1 , pp. 148-156
    • Carbonel, J.1    Feliu, J.E.2    Marco, R.3    Sols, A.4
  • 43
    • 0014753328 scopus 로고
    • Regulation of liver pyruvate kinase and phosphoenolpyruvate crossroads
    • Llorente, P.; Marco, R.; Sols, A. Regulation of liver pyruvate kinase and phosphoenolpyruvate crossroads Eur. J. Biochem. 1970, 13 (1) 45-54
    • (1970) Eur. J. Biochem. , vol.13 , Issue.1 , pp. 45-54
    • Llorente, P.1    Marco, R.2    Sols, A.3
  • 44
    • 33748498327 scopus 로고
    • Studies on the mechanism of hydrogen transport in animal tissues VI. Inhibitor studies with succinic dehydrogenase
    • Potter, V. R.; DuBois, K. P. Studies on the mechanism of hydrogen transport in animal tissues VI. Inhibitor studies with succinic dehydrogenase J. Gen. Physiol. 1943, 26 (4) 391-404
    • (1943) J. Gen. Physiol. , vol.26 , Issue.4 , pp. 391-404
    • Potter, V.R.1    Dubois, K.P.2
  • 45
    • 0009732710 scopus 로고
    • Studies on succinate dehydrogenase: I. spectral properties of the purified enzyme and formation of enzyme-competitive inhibitor complexes
    • Dervartanian, D. V.; Veeger, C. Studies on succinate dehydrogenase: I. spectral properties of the purified enzyme and formation of enzyme-competitive inhibitor complexes Biochim. Biophys. Acta 1964, 92 (2) 233-247
    • (1964) Biochim. Biophys. Acta , vol.92 , Issue.2 , pp. 233-247
    • Dervartanian, D.V.1    Veeger, C.2
  • 46
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: Kyoto Encyclopedia of Genes and Genomes
    • Kanehisa, M.; Goto, S. KEGG: Kyoto Encyclopedia of Genes and Genomes Nucleic Acids Res. 2000, 28 (1) 27-30
    • (2000) Nucleic Acids Res. , vol.28 , Issue.1 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 48
    • 2342572271 scopus 로고    scopus 로고
    • Phospholipid biosynthesis in mammalian cells
    • Vance, J. E.; Vance, D. E. Phospholipid biosynthesis in mammalian cells Biochem. Cell Biol. 2004, 82 (1) 113-128
    • (2004) Biochem. Cell Biol. , vol.82 , Issue.1 , pp. 113-128
    • Vance, J.E.1    Vance, D.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.