Antioxidant, metal-binding and DNA-damaging properties of flavonolignans: A joint experimental and computational highlight based on 7-O-galloylsilybin

Chemico-Biological Interactions

Volumn 205, Issue 3, 2013, Pages 173-180

  Vacek, Jan ^a   Zatloukalová, Martina ^a   Desmier, Thomas ^b   Nezhodová, Veronika ^a   Hrbáč, Jan ^a   Kubala, Martin ^a   Křen, Vladimír ^c   Ulrichová, Jitka ^a   Trouillas, Patrick ^b,d  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b UNIVERSITY OF LIMOGES   (France)

^c INSTITUTE OF MICROBIOLOGY   (Czech Republic)

^d UNIVERSITY OF MONS   (Belgium)

Author keywords

Albumin; Antioxidants; DNA damage; Flavonolignans; Nucleic acids; Prooxidant effects

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 7 O ALLOYLSILYBIN; COPPER ION; DNA; FLAVONOLIGNAN; REACTIVE OXYGEN METABOLITE; SILIBININ; SILVER; SILVER CHLORIDE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL BOND; CHEMICAL MODIFICATION; CHEMOLUMINESCENCE; COMPLEX FORMATION; CONTROLLED STUDY; DENSITY FUNCTIONAL THEORY; DISSOCIATION; DNA CLEAVAGE; DNA DAMAGE; DNA MODIFICATION; DRUG STRUCTURE; ELECTROCHEMISTRY; ELECTROOXIDATION; ENTHALPY; EX VIVO STUDY; EXPERIMENTAL STUDY; GEL ELECTROPHORESIS; MAGNETIC SEPARATION; METAL BINDING; MOLECULAR ORBITAL ANALYSIS; OXIDATION; PH; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET SPECTROSCOPY;

ALBUMIN; ANTIOXIDANTS; DNA-DAMAGE; FLAVONOLIGNANS; NUCLEIC ACIDS; PROOXIDANT EFFECTS;

ANTIOXIDANTS; BIPHENYL COMPOUNDS; COPPER; DNA DAMAGE; ELECTROCHEMICAL TECHNIQUES; LUMINESCENT MEASUREMENTS; MOLECULAR DYNAMICS SIMULATION; PICRATES; SILYMARIN; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84881131251     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.07.006     Document Type: Article

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