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Volumn 8, Issue 7, 2013, Pages

FTY720 Treatment in the Convalescence Period Improves Functional Recovery and Reduces Reactive Astrogliosis in Photothrombotic Stroke

Author keywords

[No Author keywords available]

Indexed keywords

FINGOLIMOD; GLIAL FIBRILLARY ACIDIC PROTEIN; POSTSYNAPTIC DENSITY PROTEIN 95; SPHINGOSINE 1 PHOSPHATE; VASCULOTROPIN A;

EID: 84881130975     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070124     Document Type: Article
Times cited : (51)

References (44)
  • 1
    • 84872054233 scopus 로고    scopus 로고
    • Heart Disease and Stroke Statistics-2013 Update A Report From the American Heart Association
    • Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, et al. (2012) Heart Disease and Stroke Statistics-2013 Update A Report From the American Heart Association. Circulation 127: 143-152.
    • (2012) Circulation , vol.127 , pp. 143-152
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3    Benjamin, E.J.4    Berry, J.D.5
  • 3
    • 43249116466 scopus 로고    scopus 로고
    • A new penumbra: transitioning from injury into repair after stroke
    • Lo EH, (2008) A new penumbra: transitioning from injury into repair after stroke. Nature Medicine 14: 497-500.
    • (2008) Nature Medicine , vol.14 , pp. 497-500
    • Lo, E.H.1
  • 4
    • 70349327371 scopus 로고    scopus 로고
    • The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia
    • Czech B, Pfeilschifter W, Mazaheri-Omrani N, Strobel MA, Kahles T, et al. (2009) The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia. Biochemical and Biophysical Research Communications 389: 251-256.
    • (2009) Biochemical and Biophysical Research Communications , vol.389 , pp. 251-256
    • Czech, B.1    Pfeilschifter, W.2    Mazaheri-Omrani, N.3    Strobel, M.A.4    Kahles, T.5
  • 5
    • 79551495392 scopus 로고    scopus 로고
    • Fingolimod provides long-term protection in rodent models of cerebral ischemia
    • Wei Y, Yemisci M, Kim HH, Yung LM, Shin HK, et al. (2010) Fingolimod provides long-term protection in rodent models of cerebral ischemia. Annals of Neurology 69: 119-129.
    • (2010) Annals of Neurology , vol.69 , pp. 119-129
    • Wei, Y.1    Yemisci, M.2    Kim, H.H.3    Yung, L.M.4    Shin, H.K.5
  • 6
    • 77449106966 scopus 로고    scopus 로고
    • Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats
    • Hasegawa Y, Suzuki H, Sozen T, Rolland W, Zhang JH, (2010) Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats. Stroke 41: 368-374.
    • (2010) Stroke , vol.41 , pp. 368-374
    • Hasegawa, Y.1    Suzuki, H.2    Sozen, T.3    Rolland, W.4    Zhang, J.H.5
  • 7
    • 70449678738 scopus 로고    scopus 로고
    • Molecular dissection of reactive astrogliosis and glial scar formation
    • Sofroniew MV, (2009) Molecular dissection of reactive astrogliosis and glial scar formation. Trends in Neurosciences 32: 638-647.
    • (2009) Trends in Neurosciences , vol.32 , pp. 638-647
    • Sofroniew, M.V.1
  • 10
    • 33645744014 scopus 로고    scopus 로고
    • Role of matrix metalloproteinases in delayed cortical responses after stroke
    • Zhao BQ, Wang S, Kim HY, Storrie H, Rosen BR, et al. (2006) Role of matrix metalloproteinases in delayed cortical responses after stroke. Nature Medicine 12: 441-445.
    • (2006) Nature Medicine , vol.12 , pp. 441-445
    • Zhao, B.Q.1    Wang, S.2    Kim, H.Y.3    Storrie, H.4    Rosen, B.R.5
  • 11
    • 0034924474 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate induces proliferation of astrocytes: regulation by intracellular signalling cascades
    • Pebay A, Toutant M, Premont J, Calvo CF, Venance L, et al. (2001) Sphingosine-1-phosphate induces proliferation of astrocytes: regulation by intracellular signalling cascades. The European Journal of Neuroscience 13: 2067-2076.
    • (2001) The European Journal of Neuroscience , vol.13 , pp. 2067-2076
    • Pebay, A.1    Toutant, M.2    Premont, J.3    Calvo, C.F.4    Venance, L.5
  • 12
    • 0142241216 scopus 로고    scopus 로고
    • Common signaling pathways link activation of murine PAR-1, LPA, and S1P receptors to proliferation of astrocytes
    • Sorensen SD, Nicole O, Peavy RD, Montoya LM, Lee CJ, et al. (2003) Common signaling pathways link activation of murine PAR-1, LPA, and S1P receptors to proliferation of astrocytes. Molecular Pharmacology 64: 1199-1209.
    • (2003) Molecular Pharmacology , vol.64 , pp. 1199-1209
    • Sorensen, S.D.1    Nicole, O.2    Peavy, R.D.3    Montoya, L.M.4    Lee, C.J.5
  • 14
    • 84859111081 scopus 로고    scopus 로고
    • FTY720 improves functional recovery after spinal cord injury by primarily nonimmunomodulatory mechanisms
    • Norimatsu Y, Ohmori T, Kimura A, Madoiwa S, Mimuro J, et al. (2012) FTY720 improves functional recovery after spinal cord injury by primarily nonimmunomodulatory mechanisms. The American Journal of Pathology 180: 1625-1635.
    • (2012) The American Journal of Pathology , vol.180 , pp. 1625-1635
    • Norimatsu, Y.1    Ohmori, T.2    Kimura, A.3    Madoiwa, S.4    Mimuro, J.5
  • 16
    • 84863228490 scopus 로고    scopus 로고
    • Vamping: Stereology-based automated quantification of fluorescent puncta size and density
    • Dumitriu D, Berger SI, Hamo C, Hara Y, Bailey M, et al. (2012) Vamping: Stereology-based automated quantification of fluorescent puncta size and density. Journal of Neuroscience Methods 209: 97-105.
    • (2012) Journal of Neuroscience Methods , vol.209 , pp. 97-105
    • Dumitriu, D.1    Berger, S.I.2    Hamo, C.3    Hara, Y.4    Bailey, M.5
  • 17
    • 33750494335 scopus 로고    scopus 로고
    • LC-MS/MS-analysis of sphingosine-1-phosphate and related compounds in plasma samples
    • Schmidt H, Schmidt R, Geisslinger G, (2006) LC-MS/MS-analysis of sphingosine-1-phosphate and related compounds in plasma samples. Prostaglandins & other lipid mediators 81: 162-170.
    • (2006) Prostaglandins & Other Lipid Mediators , vol.81 , pp. 162-170
    • Schmidt, H.1    Schmidt, R.2    Geisslinger, G.3
  • 18
    • 41149147693 scopus 로고    scopus 로고
    • Rapid morphologic plasticity of peri-infarct dendritic spines after focal ischemic stroke
    • Brown CE, Wong C, Murphy TH, (2008) Rapid morphologic plasticity of peri-infarct dendritic spines after focal ischemic stroke. Stroke 39: 1286-1291.
    • (2008) Stroke , vol.39 , pp. 1286-1291
    • Brown, C.E.1    Wong, C.2    Murphy, T.H.3
  • 20
    • 79961030697 scopus 로고    scopus 로고
    • Disturbance of perineuronal nets in the perilesional area after photothrombosis is not associated with neuronal death
    • Karetko-Sysa M, Skangiel-Kramska J, Nowicka D, (2011) Disturbance of perineuronal nets in the perilesional area after photothrombosis is not associated with neuronal death. Experimental Neurology 231: 113-126.
    • (2011) Experimental Neurology , vol.231 , pp. 113-126
    • Karetko-Sysa, M.1    Skangiel-Kramska, J.2    Nowicka, D.3
  • 21
    • 25844487075 scopus 로고    scopus 로고
    • Apoptotic cell death progression after photothrombotic focal cerebral ischaemia: effects of the lipophilic iron chelator 2,2′-dipyridyl
    • Van Hoecke M, Prigent-Tessier A, Bertrand N, Prevotat L, Marie C, et al. (2005) Apoptotic cell death progression after photothrombotic focal cerebral ischaemia: effects of the lipophilic iron chelator 2,2′-dipyridyl. The European Journal of Neuroscience 22: 1045-1056.
    • (2005) The European Journal of Neuroscience , vol.22 , pp. 1045-1056
    • Van Hoecke, M.1    Prigent-Tessier, A.2    Bertrand, N.3    Prevotat, L.4    Marie, C.5
  • 22
    • 0027197190 scopus 로고
    • Semisynthetic sphingolipids prevent protein kinase C translocation and neuronal damage in the perifocal area following a photochemically induced thrombotic brain cortical lesion
    • Kharlamov A, Guidotti A, Costa E, Hayes R, Armstrong D, (1993) Semisynthetic sphingolipids prevent protein kinase C translocation and neuronal damage in the perifocal area following a photochemically induced thrombotic brain cortical lesion. The Journal of Neuroscience 13: 2483-2494.
    • (1993) The Journal of Neuroscience , vol.13 , pp. 2483-2494
    • Kharlamov, A.1    Guidotti, A.2    Costa, E.3    Hayes, R.4    Armstrong, D.5
  • 23
    • 0032706652 scopus 로고    scopus 로고
    • Neuroprotective effects of an antioxidant in cortical cerebral ischemia: prevention of early reduction of the apurinic/apyrimidinic endonuclease DNA repair enzyme
    • Chang YY, Fujimura M, Morita-Fujimura Y, Kim GW, Huang CY, et al. (1999) Neuroprotective effects of an antioxidant in cortical cerebral ischemia: prevention of early reduction of the apurinic/apyrimidinic endonuclease DNA repair enzyme. Neuroscience Letters 277: 61-64.
    • (1999) Neuroscience Letters , vol.277 , pp. 61-64
    • Chang, Y.Y.1    Fujimura, M.2    Morita-Fujimura, Y.3    Kim, G.W.4    Huang, C.Y.5
  • 24
    • 0027526541 scopus 로고
    • The effects of chlormethiazole and nimodipine on cortical infarct area after focal cerebral ischaemia in the rat
    • Snape MF, Baldwin HA, Cross AJ, Green AR, (1993) The effects of chlormethiazole and nimodipine on cortical infarct area after focal cerebral ischaemia in the rat. Neuroscience 53: 837-844.
    • (1993) Neuroscience , vol.53 , pp. 837-844
    • Snape, M.F.1    Baldwin, H.A.2    Cross, A.J.3    Green, A.R.4
  • 25
    • 84864275231 scopus 로고    scopus 로고
    • Photothrombosis-induced infarction of the mouse cerebral cortex is not affected by the Nrf2-activator sulforaphane
    • Porritt MJ, Andersson HC, Hou L, Nilsson A, Pekna M, et al. (2012) Photothrombosis-induced infarction of the mouse cerebral cortex is not affected by the Nrf2-activator sulforaphane. PloS one 7: e41090.
    • (2012) PloS One , vol.7
    • Porritt, M.J.1    Andersson, H.C.2    Hou, L.3    Nilsson, A.4    Pekna, M.5
  • 26
    • 79960301614 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate regulates matrix metalloproteinase-9 expression and breast cell invasion through S1P3-Galphaq coupling
    • Kim ES, Kim JS, Kim SG, Hwang S, Lee CH, et al. (2011) Sphingosine 1-phosphate regulates matrix metalloproteinase-9 expression and breast cell invasion through S1P3-Galphaq coupling. Journal of Cell Science 124: 2220-2230.
    • (2011) Journal of Cell Science , vol.124 , pp. 2220-2230
    • Kim, E.S.1    Kim, J.S.2    Kim, S.G.3    Hwang, S.4    Lee, C.H.5
  • 27
    • 33645742989 scopus 로고    scopus 로고
    • Remodeling of synaptic structures in the motor cortex following spinal cord injury
    • Kim BG, Dai HN, McAtee M, Vicini S, Bregman BS, (2006) Remodeling of synaptic structures in the motor cortex following spinal cord injury. Experimental Neurology 198: 401-415.
    • (2006) Experimental Neurology , vol.198 , pp. 401-415
    • Kim, B.G.1    Dai, H.N.2    McAtee, M.3    Vicini, S.4    Bregman, B.S.5
  • 28
    • 3843136369 scopus 로고    scopus 로고
    • A morphological correlate of synaptic scaling in visual cortex
    • Wallace W, Bear MF, (2004) A morphological correlate of synaptic scaling in visual cortex. The Journal of Neuroscience 24: 6928-6938.
    • (2004) The Journal of Neuroscience , vol.24 , pp. 6928-6938
    • Wallace, W.1    Bear, M.F.2
  • 29
    • 20444369248 scopus 로고    scopus 로고
    • Spine-neck geometry determines NMDA receptor-dependent Ca2+ signaling in dendrites
    • Noguchi J, Matsuzaki M, Ellis-Davies GC, Kasai H, (2005) Spine-neck geometry determines NMDA receptor-dependent Ca2+ signaling in dendrites. Neuron 46: 609-622.
    • (2005) Neuron , vol.46 , pp. 609-622
    • Noguchi, J.1    Matsuzaki, M.2    Ellis-Davies, G.C.3    Kasai, H.4
  • 30
    • 0024473444 scopus 로고
    • Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics
    • Harris KM, Stevens JK, (1989) Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics. The Journal of neuroscience: the official journal of the Society for Neuroscience 9: 2982-2997.
    • (1989) The Journal of Neuroscience: The Official Journal of the Society for Neuroscience , vol.9 , pp. 2982-2997
    • Harris, K.M.1    Stevens, J.K.2
  • 32
    • 70349675503 scopus 로고    scopus 로고
    • Implications of vascular endothelial growth factor for postischemic neurovascular remodeling
    • Hermann DM, Zechariah A, (2009) Implications of vascular endothelial growth factor for postischemic neurovascular remodeling. Journal of Cerebral Blood Flow and Metabolism 29: 1620-1643.
    • (2009) Journal of Cerebral Blood Flow and Metabolism , vol.29 , pp. 1620-1643
    • Hermann, D.M.1    Zechariah, A.2
  • 33
    • 79955399440 scopus 로고    scopus 로고
    • 17beta-estradiol increases astrocytic vascular endothelial growth factor (VEGF) in adult female rat hippocampus
    • Barouk S, Hintz T, Li P, Duffy AM, MacLusky NJ, et al. (2011) 17beta-estradiol increases astrocytic vascular endothelial growth factor (VEGF) in adult female rat hippocampus. Endocrinology 152: 1745-1751.
    • (2011) Endocrinology , vol.152 , pp. 1745-1751
    • Barouk, S.1    Hintz, T.2    Li, P.3    Duffy, A.M.4    MacLusky, N.J.5
  • 34
    • 2542528668 scopus 로고    scopus 로고
    • Temporal profile of matrix metalloproteinases and their inhibitors after spontaneous intracerebral hemorrhage: relationship to clinical and radiological outcome
    • Alvarez-Sabin J, Delgado P, Abilleira S, Molina CA, Arenillas J, et al. (2004) Temporal profile of matrix metalloproteinases and their inhibitors after spontaneous intracerebral hemorrhage: relationship to clinical and radiological outcome. Stroke 35: 1316-1322.
    • (2004) Stroke , vol.35 , pp. 1316-1322
    • Alvarez-Sabin, J.1    Delgado, P.2    Abilleira, S.3    Molina, C.A.4    Arenillas, J.5
  • 35
  • 36
    • 84865297437 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate modulates expression of vascular endothelial growth factor in human articular chondrocytes: a possible new role in arthritis
    • Masuko K, Murata M, Beppu M, Nakamura H, Kato T, et al. (2012) Sphingosine-1-phosphate modulates expression of vascular endothelial growth factor in human articular chondrocytes: a possible new role in arthritis. International Journal of Rheumatic Diseases 15: 366-373.
    • (2012) International Journal of Rheumatic Diseases , vol.15 , pp. 366-373
    • Masuko, K.1    Murata, M.2    Beppu, M.3    Nakamura, H.4    Kato, T.5
  • 37
    • 77951880587 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate induces human endothelial VEGF and MMP-2 production via transcription factor ZNF580: novel insights into angiogenesis
    • Sun HY, Wei SP, Xu RC, Xu PX, Zhang WC, (2010) Sphingosine-1-phosphate induces human endothelial VEGF and MMP-2 production via transcription factor ZNF580: novel insights into angiogenesis. Biochemical and Biophysical Research Communications 395: 361-366.
    • (2010) Biochemical and Biophysical Research Communications , vol.395 , pp. 361-366
    • Sun, H.Y.1    Wei, S.P.2    Xu, R.C.3    Xu, P.X.4    Zhang, W.C.5
  • 38
    • 34147095398 scopus 로고    scopus 로고
    • The immunosuppressant FTY720 inhibits tumor angiogenesis via the sphingosine 1-phosphate receptor 1
    • Schmid G, Guba M, Ischenko I, Papyan A, Joka M, et al. (2007) The immunosuppressant FTY720 inhibits tumor angiogenesis via the sphingosine 1-phosphate receptor 1. Journal of Cellular Biochemistry 101: 259-270.
    • (2007) Journal of Cellular Biochemistry , vol.101 , pp. 259-270
    • Schmid, G.1    Guba, M.2    Ischenko, I.3    Papyan, A.4    Joka, M.5
  • 40
    • 58149345610 scopus 로고    scopus 로고
    • Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain
    • Kimura A, Ohmori T, Kashiwakura Y, Ohkawa R, Madoiwa S, et al. (2008) Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain. Stroke 39: 3411-3417.
    • (2008) Stroke , vol.39 , pp. 3411-3417
    • Kimura, A.1    Ohmori, T.2    Kashiwakura, Y.3    Ohkawa, R.4    Madoiwa, S.5
  • 41
    • 0030961305 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum
    • Yatomi Y, Igarashi Y, Yang L, Hisano N, Qi R, et al. (1997) Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum. Journal of Biochemistry 121: 969-973.
    • (1997) Journal of Biochemistry , vol.121 , pp. 969-973
    • Yatomi, Y.1    Igarashi, Y.2    Yang, L.3    Hisano, N.4    Qi, R.5
  • 43
    • 80051991367 scopus 로고    scopus 로고
    • Sphingosine kinase 1 and sphingosine 1-phosphate receptor 3 are functionally upregulated on astrocytes under pro-inflammatory conditions
    • Fischer I, Alliod C, Martinier N, Newcombe J, Brana C, et al. (2011) Sphingosine kinase 1 and sphingosine 1-phosphate receptor 3 are functionally upregulated on astrocytes under pro-inflammatory conditions. PloS one 6: e23905.
    • (2011) PloS One , vol.6
    • Fischer, I.1    Alliod, C.2    Martinier, N.3    Newcombe, J.4    Brana, C.5
  • 44
    • 26844435654 scopus 로고    scopus 로고
    • Rodent models of focal stroke: size, mechanism, and purpose
    • Carmichael ST, (2005) Rodent models of focal stroke: size, mechanism, and purpose. NeuroRx 2: 396-409.
    • (2005) NeuroRx , vol.2 , pp. 396-409
    • Carmichael, S.T.1


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