Are lymphoid follicles important in the pathogenesis of chronic obstructive pulmonary disease?

American Journal of Respiratory and Critical Care Medicine

Volumn 188, Issue 3, 2013, Pages 267-269

  Hansbro, Philip M ^a   Knight, Darryl A ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; B CELL MATURATION ANTIGEN; CXCL13 CHEMOKINE; CXCL9 CHEMOKINE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MACROPHAGE INFLAMMATORY PROTEIN 3BETA;

B LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHRONIC INFLAMMATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL FEATURE; DENDRITIC CELL; EDITORIAL; GENE EXPRESSION; HUMAN; INFLAMMATORY CELL; LUNG LAVAGE; LYMPH FOLLICLE; MACROPHAGE; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RISK ASSESSMENT;

ANIMALS; CHEMOKINE CXCL13; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RNA, MESSENGER; SMOKE; SMOKING; TOBACCO;

EID: 84881121048     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201306-1073ED     Document Type: Editorial

References (15)

1. World Health Organization. Chronic obstructive pulmonary disease (COPD). Fact Sheet 315. Geneva, Switzerland: World Health Organization; 2012 [accessed 2013 July 17]. Available from: Http://www. who.int/respiratory/copd/en/
2. Vlahos R, Bozinovski S, Gualano RC, Ernst M, Anderson GP. Modelling COPD in mice. Pulm Pharmacol Ther 2006;19:12-17.
3. Keely S, Talley NJ, Hansbro PM. Pulmonary-intestinal cross-talk in mucosal inflammatory disease. Mucosal Immunol 2012;5:7-18.
4. Calverley PM, Anderson JA, Celli B, Ferguson GT, Jenkins C, Jones PW, Yates JC, Vestbo J; TORCH investigators. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med 2007;356:775-789.
5. Hsu AC, See HV, Hansbro PM, Wark PA. Innate immunity to influenza in chronic airways diseases. Respirology 2012;17:1166-1175.
6. Yang IA, Fong KM, Sim EH, Black PN, Lasserson TJ. Inhaled corticosteroids for stable chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2007;(2):CD002991.
7. Bracke KR, Verhamme FM, Seys LJ, Bantsimba-Malanda C, Cunoosamy DM, Herbst R, Hammad H, Lambrecht BN, Joos GF, Brusselle GG. Role of CXCL13 in cigarette smoke-induced lymphoid follicle formation and COPD. Am J Respir Crit Care Med 2013;188:343-355.
8. van der Strate BW, Postma DS, Brandsma CA, Melgert BN, Luinge MA, GeerlingsM, Hylkema MN, van den Berg A, TimensW, Kerstjens HA. Cigarette smoke-induced emphysema: A role for the B cell? Am J Respir Crit Care Med 2006;173:751-758.
9. Bracke KR, D'hulst AI, Maes T, Moerloose KB, Demedts IK, Lebecque S, Joos GF, Brusselle GG. Cigarette smoke-induced pulmonary inflammation and emphysema are attenuated in CCR6-deficient mice. J Immunol 2006;177:4350-4359.
10. Saetta M, Di Stefano A, Turato G, Facchini FM, Corbino L, Mapp CE, Maestrelli P, Ciaccia A, Fabbri LM. CD81 T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998;157:822-826.
11. Ansel KM, Ngo VN, Hyman PL, Luther SA, Förster R, Sedgwick JD, Browning JL, Lipp M, Cyster JG. A chemokine-driven positive feedback loop organizes lymphoid follicles. Nature 2000;406: 309-314.
12. O'Connor BP, Raman VS, Erickson LD, Cook WJ, Weaver LK, Ahonen C, Lin LL, Mantchev GT, Bram RJ, Noelle RJ. BCMA is essential for the survival of long-lived bone marrow plasma cells. J ExpMed 2004;199:91-98.
13. D'hulst AI, Maes T, Bracke KR, Demedts IK, Tournoy KG, Joos GF, Brusselle GG. Cigarette smoke-induced pulmonary emphysema in scidmice. Is the acquired immune system required? Respir Res 2005;6:147-160.
14. Gaschler GJ, Skrtic M, Zavitz CC, Lindahl M, Onnervik PO, Murphy TF, Sethi S, Stämpfli MR. Bacteria challenge in smoke-exposed mice exacerbates inflammation and skews the inflammatory profile. Am J Respir Crit Care Med 2009;179:666-675.
15. Beckett EL, Stevens RL, Jarnicki AG, Kim RY, Hanish I, Hansbro NG, Deane A, Keely S, Horvat JC, Yang M, et al. A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis. J Allergy Clin Immunol 2013;131: 752-762.